Submitted to: Electronic Publication
Publication Type: Other
Publication Acceptance Date: 6/12/2006
Publication Date: 9/16/2006
Citation: Jeha, G., Haymond, M.W. 2006. Treatment and complications of diabetic ketoacidosis in children. In: Rose, B.D., editors. UpToDate Online Journal [serial online]. Available: http://www.uptodate.com. Interpretive Summary:
Technical Abstract: Diabetic ketoacidosis (DKA) is the leading cause of morbidity and mortality in children with type 1 diabetes mellitus (DM), ranging from 0.15% to 0.31%. In addition, DKA also can occur in children with type 2 DM across many ethnic groups but particularly in obese African-American adolescents. The management of DKA in children, which is based upon the large collective experience of children with type 1 DM, will be reviewed here. There is limited experience in the management and outcomes of DKA in children with type 2 DM, although the same principles should apply. The clinical manifestations and diagnosis of DKA in children and the pathogenesis of DKA are discussed elsewhere.