Submitted to: Veterinary Clinics of North America
Publication Type: Book / Chapter
Publication Acceptance Date: 9/29/2006
Publication Date: 10/20/2006
Citation: Stromberg, B.E., Gasbarre, L.C. 2006. Gastrointestinal nematode control programs. Veterinary Clinics of North America. 22:543-565.
Technical Abstract: Control strategies for nematode parasites rely on understanding the relationship between the parasites and their hosts. Specifically identification of crucial points of interaction in the environment provided by the host, including genetics and the immune response, as well as critical periods in the physical environment in which the eggs and larval stages must develop, provide the basis for these programs. Once these targets are identified and the interactions are understood, cost effective sustainable programs can be developed using currently available antiparasitic compounds. Resistance to the major classes of anthelmintic compounds requires that new approaches be considered, such as immunity and/or genetics of the host. Additionally, the efficacy of these compounds can be expanded with combination or concomitant use. There has also been an increased study of novel approaches that include fungi, and the use of elements such as copper and plant products. The goal of this chapter is to explore each of these areas to allow the reader to appreciate how various approaches may be developed and incorporated into an effective parasite control program.