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United States Department of Agriculture

Agricultural Research Service


item Cheatham, Rachel
item Lieberman, Harris
item Das, Sai Krupa
item Saltzman, Edward
item Gilhooly, Cheryl
item Golden, Julie
item Roberts, Susan

Submitted to: Experimental Biology
Publication Type: Abstract Only
Publication Acceptance Date: 12/1/2005
Publication Date: 3/1/2006
Citation: Cheatham, R.A., Lieberman, H.R., Das, S., Saltzman, E., Gilhooly, C.L., Golden, J.K., Roberts, S. 2006. Effects of dietary glycemic load on mood during caloric restriction. Experimental Biology. 20:A426.

Interpretive Summary:

Technical Abstract: A 1-yr randomized hypocaloric trial tested the effects of high glycemic load (HG: 60% high glycemic index carbohydrate, 20% fat, 20% protein) and low glycemic load (LG: 40% lower glycemic index carbohydrate, 30% fat, 30% protein) diets on mood parameters in 28 healthy men and women (mean+/-SD, age 35+/-6y; BMI 27.6+/-1.4kg/m2). Subjects were randomized to the HG and LG diets, both at 30% caloric restriction. All food was provided for 6 mo, and then subjects were instructed to self-administer the same dietary patterns for a further 6mo. Self-reported mood was assessed with the Profile of Mood States (POMS), providing six sub-scales: tension-anxiety (T), depression-dejection (D), anger-hostility (A), fatigue-inertia (F), vigor-activity (V) and confusion-bewilderment (C). Using a mixed effects model with repeated measures at baseline, 1, 6 and 12 mo and controlling for weight loss, T differed over time in a manner dependent upon diet (time x diet p=0.046), with an overall decrease of T among the LG group. On post-hoc testing, the 0-6 mo difference scores for T (p=0.006) and D (p=0.033) varied between diets, with T and D decreasing on LG. The 1-yr difference score for F (p=0.011) differed between diets, with F decreasing on LG. These results suggest that consumption of the LG diet used in this study improves several mood parameters during caloric restriction, compared to consumption of a HG diet.

Last Modified: 06/24/2017
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