Submitted to: Nature Reviews Genetics
Publication Type: Review article
Publication Acceptance Date: 7/25/2005
Publication Date: 9/1/2005
Citation: Krizek, B.A., Fletcher, J.C. 2005. Molecular mechanisms of flower development: an armchair guide. Nature Reviews Genetics. 6(9):688-698. Interpretive Summary:
Technical Abstract: An afternoon stroll through an English garden reveals the breathtaking beauty and enormous diversity of flowering plants. The extreme variation of flower morphologies, combined with the relative simplicity of floral structures and the wealth of floral mutants available, has made the flower an excellent model for studying developmental cell-fate specification, morphogenesis and tissue patterning. Recent molecular genetic studies have begun to reveal the transcriptional regulatory cascades that control early patterning events during flower formation, the dynamics of the gene-regulatory interactions, and the complex combinatorial mechanisms that create a distinct final floral architecture and form.