Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 11/1/2005
Publication Date: 12/1/2005
Citation: Laegreid, W.W., Clawson, M.L., Heaton, M.P. 2005. Use of bovine single nucleotide polymorphism markers for confirmation of identity and parentage [abstract]. United States Animal Health Association. p. 710. Interpretive Summary:
Technical Abstract: Development of animal identification systems for use in the event of livestock disease outbreaks and public health investigations has recently become a national priority. While various tagging, implant, and/or other technologies will form a sound basis for an identification system, they remain subject to error or fraud. Thus, a means to audit and verify the performance of identification systems will be required. DNA marker technology represents a promising means for confirming the identity and parentage of an animal because DNA is the only informative identification that 1) is integral to most parts of an animal, 2) remains stable throughout the life of the animal, and 3) provides a “code” unique to the animal. Compared with other types of DNA markers, single nucleotide polymorphisms (SNPs) are attractive because they are abundant, genetically stable, and amenable to high-throughput automated analysis. In cattle, the challenge has been to identify a minimal set of SNPs with sufficient power for use in a variety of popular breeds and crossbred populations. We report the development of a set of bovine SNP markers with high informativity in U.S. cattle populations and provide examples of their use in confirmation of identity or parentage in field situations.