Author
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Bannerman, Douglas |
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Wall, Robert |
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Submitted to: Information Systems for Biotechnology News Report
Publication Type: Popular Publication Publication Acceptance Date: 4/22/2005 Publication Date: 5/2/2005 Citation: Bannerman, D.D., Wall, R.J. 2005. A novel strategy for the prevention of Staphylococcus aureus-induced mastitis in dairy cows. Information Systems for Biotechnology(ISB)News Report. May 2005 Issue:1-4. Interpretive Summary: Technical Abstract: Mastitis is an inflammation of the mammary gland that most frequently develops in cows in response to intramammary bacterial infection. Mastitis remains one of the most prevalent and costly production diseases in dairy herds worldwide. Although management practices can reduce the incidence of mastitis, the ubiquitous nature of mastitis pathogens in the cow's environment precludes complete prevention through good management alone. Antimicrobial therapeutics for treating mastitis remain limited and are often sub-optimal. The development of new strategies for the prevention and/or treatment of mastitis continues to be a high priority among animal health initiatives. This article reviews a novel strategy for the prevention of Staphylococcus aureus-induced mastitis via the development of transgenic cattle that express lysostaphin in the mammary gland. |
