Submitted to: Encyclopedia of Animal Science
Publication Type: Book / Chapter
Publication Acceptance Date: 11/30/2005
Publication Date: 3/27/2006
Citation: Nicholson, E.M., Richt, J.A. 2006. Transmissible spongiform encephalopathies: biology and disease. Encyclopedia of Animal Science [online]. 1(1). Available: http://www.dekker.com/sdek/abstract~db=enc~content=a713617944.
Technical Abstract: This review summarizes the basic concepts and terminology of TSE biology with particular attention paid to the more commonly occurring TSEs. It is important to note that while the basic principles remain constant across TSEs, significant differences exist between various TSE agents in different species necessitating study in natural hosts. Research on prion diseases is a rapidly evolving field involving scientists from a wide spectrum of basic and applied disciplines; ultimately, many aspects of prion diseases are still unknown, inconclusive and sometimes even controversial.