Submitted to: Germplasm Release
Publication Type: Germplasm Release
Publication Acceptance Date: 9/11/2004
Publication Date: 10/2/2004
Citation: Connor, E.E. 2004. Physical mapping of eif4ebp1 and leprotl1 genes in cattle. Germplasm Release. Accession numbers BV209032-BV209035. Interpretive Summary: This is a Germplasm Release. No Interpretive Summary required.
Technical Abstract: Quantitative trait loci (QTL) associated with body condition of dairy cattle (dairy character) were identified by our laboratory within two regions of bovine chromosome 27 (BTA27); one QTL peak is within the 30-50 cM region of BTA27 and the second is positioned near the telomere. At present, we rely primarily on human-bovine comparative chromosome maps to identify positional candidate genes contributing to these QTL. Two genes, EIF4EBP1 and LEPROTL1, positioned on human chromosome 8 at 30-40 Mb were selected for radiation hybrid mapping in cattle to improve the human-bovine comparative map, particularly near the 40 cM region of BTA27. Sequence tagged sites were developed for each gene and sequences associated with these genes were submitted to the GenBank dbSTS database. GenBank Accession Nos. BV209032-BV209035