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ARS Home » Research » Publications at this Location » Publication #163548
Title: PASSIVE PROTECTION AGAINST TWO EIMERIA SPECIES IN CHICKENS BY ORALLY ADMINISTERED ANTIBODIES SPECIFIC FOR A SINGLE EIMERIA PROTEIN

Author
item Lillehoj, Hyun
item NGYYEN, SA - GHEN CORP. JAPAN
item DONAHUE, JOHN - GHEN CORP. JAPAN
item YOKOHAMA, A - GHEN CORP. JA[AM
item KODAMA, Y - GHEN CORP. JAPAN

Submitted to: American Veterinary Medical Association Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 2/20/2004
Publication Date: 7/20/2004
Citation: Lillehoj, H.S., Ngyyen, S.Y., Donahue, J.P., Yokohama, A.H., Kodama, Y. 2004. Passive protection against two eimeria species in chickens by orally administered antibodies specific for a single eimeria protein. American Veterinary Medical Association Abstract p. 21.

Interpretive Summary:

Technical Abstract: The protective effect of chicken egg antibody (IgY) powder prepared from hens hyperimmunized with a recombinant protein (3-1E) from Eimeria acervulina merozoites was evaluated. . The 3 treatment groups were given feed containing 0.1, 1 and 10% of the IgY powder, respectively. The chickens were orally challenged with 103 E. tenella or 5 × 103 E. acervulina oocysts. The best results were observed in the groups which received 10% of IgY powder and the oocyst production was significantly reduced. Significant improvement in body weight gain was also seen. The results indicate that the passive immunization of chickens with antigen-specific IgY powder is a promising method to confer protection against coccidiosis.