Submitted to: National Meeting of Institute of Food Technologists/Food Expo
Publication Type: Abstract only
Publication Acceptance Date: 6/1/2003
Publication Date: 7/1/2003
Citation: MANTHEY, J.A. PHYTOCHEMICALS AND THEIR BIOLOGICAL ACTIVITY FROM THE CITRUS PROCESSING WASTE STEAM. NATIONAL MEETING OF INSTITUTE OF FOOD TECHNOLOGISTS/FOOD EXPO. 2003. p. 45. Abstract No. 19-2. Interpretive Summary:
Technical Abstract: Citrus processing waste streams contain high amounts of the secondary natural products that normally occur in the peel. Two of the main classes of natural products that have attracted attention for their potential health-promoting properties include the phenolic compounds and the triterpenoid limonoids. Both classes of compounds occur primarily as glycosides. The phenolic compounds are comprised of several main chemical groups, including numerous flavonoids, hydroxycinnamates, and other conjugated phenolic species. Of the flavonoids, the polymethoxylated flavones have received attention as potential anticancer and antiinflammatory agents. These actions may be due to their inhibition of key enzymes involved in cell activation processes. New findings show that these compounds may also bind human adenosine receptors, and it is speculated that the biological actions of these compounds in mammals may be more complex than initially anticipated. The flavonoid glycosides have also been shown to exhibit anticarcinogenic as well as antiinflammatory actions. Some of these actions are based on their antioxidant properties which are strongly synergistic with vitamin C. The limonoids have been also studied for their anticancer actions. It is anticipated that the limonoids and flavonoids may exert biological actions via separate mechanisms, and synergy between these sets of compounds are likely. These findings provide a rationale for the development of new health-promoting based value added products from these compounds.