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Title: NET PORTAL APPEARANCE OF AMINO ACIDS AND GLUCOSE, AND ENERGY EXPENDITURE BY PORTAL VEIN-DRAINED ORGANS IN GROWING PIGS FED CASEIN AND CORNSTARCH BASED DIETS OR A WHEAT SHORTS BASED DIET

Author
item YIN, Y.
item HUANG, R.
item Yen, Jong Tseng
item LIBAO-MERCADO, A.J.
item DE LANGE, C.F.M.

Submitted to: Proceedings of the International Symposium on Digestive Physiology in Pigs
Publication Type: Proceedings
Publication Acceptance Date: 3/14/2003
Publication Date: 5/14/2003
Citation: YIN, Y.L., HUANG, R.L., YEN, J., LIBAO-MERCADO, A., DE LANGE, C. NET PORTAL APPEARANCE OF AMINO ACIDS AND GLUCOSE, AND ENERGY EXPENDITURE BY PORTAL VEIN-DRAINED ORGANS IN GROWING PIGS FED CASEIN AND CORNSTARCH BASED DIETS OR A WHEAT SHORTS BASED DIET. PROCEEDINGS OF THE INTERNATIONAL SYMPOSIUM ON DIGESTIVE PHYSIOLOGY IN PIGS, BANFF, ALBERTA, CANADA. VOLUME 2, PAGES 340-342. 2003.

Interpretive Summary:

Technical Abstract: Net appearance of amino acids (AA) and glucose in the portal vein and heat production in the portal vein drained visceral organs (PVDO) was investigated in a study with four growing pigs (average initial body weight 24 kg) fitted with catheters in the portal vein, ileal vein and carotid artery. The animals were fed a casein based diet (Cs) containing 8.5% casein, 67.2% cornstarch, or a wheat shorts based diet (Ws) containing 33.9% cornstarch and 45.0% wheat short. Diets were formulated to contain similar ratios of apparent ileal digestible lysine and threonine to DE. The experiment was conducted using a crossover design and included two experimental periods. Each period lasted 7 d with 1 d (d 7) of blood sampling. Daily feed allowance was maintained at 2.6 x maintenance DE requirements (110 Kcal of DE/kg of BW0.75) and offered in three equal meals daily (0800, 1600 and 2400h). Portal and arterial blood samples were obtained simultaneously at 0700h and hourly during the 8-h post-prandial period. Portal blood or blood plasma flow was measured using p-aminohippuric acid infused continuously into the ileal vein. The O2 consumption and CO2 production, and the net portal appearance of glucose were calculated from portal blood flow rate and porto-arterial whole blood concentration differences. Net AA appearance was based on blood plasma measurements. Net portal appearance of AA (% of intake) was lower (P<0.10) for WSs than SCs: arginine (24 vs 73), isoleucine (25 vs 54), leucine (22 vs 54), lysine (20 vs 53), methionine (24 vs 50), threonine (19 vs 39), valine (22 vs 54), alaline (99 vs 366), aspartic acid (3 vs 9), glutamic acid (-1 vs 9), glycine (44 vs 100), serine (24 vs 45). Dietary difference was greater for net portal absorption than for ileal amino acid digestibility. Net portal appearance of glucose was relatively high and did not differ between diets: 80.4% for Cs and 76.3% for Ws (P>0.10). Heat production in the PVDO during 8 h after feeding was 13.0 (Cs) and 16.1 (Ws) KJ/kgBW (SE 1.34; P>0.10). The PVDO consume a much greater proportion of dietary intake of AA than glucose. These data suggest that catabolism in PVDO dominates the first-pass metabolism of dietary AA of growing pigs and that there are substantial diet effects on this catabolism.