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item Fayer, Ronald
item Xiao, U.
item Morgan, U.
item Trout, James
item Dubey, Jitender
item Lal, A.

Submitted to: American Society of Parasitology
Publication Type: Abstract Only
Publication Acceptance Date: 5/1/2001
Publication Date: 6/30/2001
Citation: Fayer, R., Xiao, U.M., Morgan, U.M., Trout, J.M., Dubey, J.P., Lal, A.A. 2001. Cryptosporidium Canis is Infectious for Dogs, Humans, and Cattle.[Meeting Abstract]. American Society of Parasitology, Albuquerque, New Mexico, June 30, 2001 - July 3, 2001.

Interpretive Summary:

Technical Abstract: Previous reports described a unique genotype of Cryptosporidium isolated from feces of dogs and humans, and referred to this as C. parvum canine genotype. Recently, this genotype has been identified as a new species and named C. canis. Oocysts of C. canis were obtained from both a dog and 2 humans (one HIV-positive and the other HIV-negative). Oocysts from both sources were morphologically indistinguishable from those of C. parvum. Oocysts from the dog were fed to a calf, mice, rats, rabbits, and guinea pigs; those from the humans were fed to a calf and guinea pigs. Unlike C. parvum genotype 1 (human genotype), C. canis oocysts were infectious for calves. Unlike C. parvum genotype 2 (bovine genotype), C canis oocysts were not infectious for mice, or the other mammalian species tested. Furthermore, C. canis oocysts were markedly different from all known species of Cryptosporidium based on sequence data for the 18S rDNA and HSP 70 gene.