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Title: RECOMBINATION BETWEEN ALV-J AND ENDOGENOUS SUBGROUP E VIRUSES

Author
item Hunt, Henry
item Lupiani, Blanca
item Fadly, Aly

Submitted to: International Symposium On Alv J
Publication Type: Proceedings
Publication Acceptance Date: 6/5/2000
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: Two recombinant Avian leukosis subgroup J viruses, ADOL 5701A and ADOL 6803A, carrying a chimeric A/E envelope (subgroup A gp85 and subgroup E gp37) with J LTRs have been isolated and characterized. These viruses were identified by their ability to replicate in DF-1/J, a recombinant chicken embryo fibroblast (CEF) cell line expressing the subgroup J envelope that is resistant to subgroup J infection (C/J). The recombination creating these viruses occurred during the propagation of subgroup J viruses in CEF from the alv6 chicken line, a line that carries a replication defective recombinant endogenous virus possessing the same chimeric subgroup A/E envelope (RAV 0-A1).