GLOBAL GENE EXPRESSION ANALYSIS TO INVESTIGATE MUCOSAL IMMUNE RESPONSE TO AVIAN INFLUENZA IN KOREAN NATIVE CHICKEN BREEDS
Project Number: 1245-32000-097-06
Start Date: Aug 01, 2008
End Date: Jul 31, 2013
Thorough investigation of the immunogenetic responses involved in host-pathogen interactions in Avian Influenza will lead to better understanding of genetic countrol of host response to AI and the identification of immunogenetic mechanisms which will facilitate the development of novel vaccination strategies against AI.
APDL plans to apply avian cDNA intestinal IEL microarray (AVIELA) chips which were developed in the laboratory at BARC to characterize the differential immune response patterns of different genetic breeds of broiler chickens with different disease phenotypes.