Research Project: Elucidating Phytonutrient Bioavailability, Health Promoting Effects and Mechanisms of Existing/Emerging Foods and Beverages

Location: Diet, Genomics and Immunology Laboratory

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Impact of roasting on javamide-I/-II in Arabica and Robusta coffee beans - (Peer Reviewed Journal)
Park, J.B., Peters, R.C., Novotny Dura, J. 2023. Impact of roasting on javamide-I/-II in Arabica and Robusta coffee beans. Food Chemistry. 412:135586. https://doi.org//10.1016/j.foodchem.2023.135586.

The NCCC Report to Congress: Prevention in People with Prediabetes - (Peer Reviewed Journal)
Boltri, J., Tracer, H., Strogatz, D., Schumacher, P., Fukagawa, N.K., Shell, D., Wu, S., Idzik, S., Herman, W., Powell, C. 2023. The NCCC Report to Congress: Prevention in people with prediabetes. Diabetes Care. 46(2):e39-e50. https://doi.org/10.2337/dc22-0620.

The national clinical care commission report to congress: recommendations to better leverage federal policies and programs to prevent and control diabetes - (Peer Reviewed Journal)
Schillinger, D., Bullock, A., Powell, C., Fukagawa, N.K., Greenlee, C.M., Towne, J., Gonzalvo, J.D., Lopata, A.M., Cook IV, W., Herman, W.H., Albright, A., Bolen, S., Boltri, J.M., Chong, W., Conlin, P.R., Dokun, A., Hawkins, M., Idzik, S., Leake, E., Linder, B., Marx, B., Schumacher, P., Shell, D., Strogatz, D., Tracer, H., Wu, S. 2023. The National Clinical Care Commission Report to Congress: Recommendations to better leverage federal policies and programs to prevent and control diabetes. Diabetes Care. 46(2):255-261. https://doi.org/10.2337/dc22-1587.

Individual variabilities in adipose stem cell proliferation, gene expression and responses to lipopolysaccharide stimulation - (Peer Reviewed Journal)
Yasmin, R., Pham, Q., Fukagawa, N.K., Wang, T.T. 2022. Individual variabilities in adipose stem cell proliferation, gene expression and responses to lipopolysaccharide stimulation. International Journal of Molecular Sciences. 23:12534. https://doi.org/10.3390/ijms232012534.

Leveraging Federal Programs for Population-Level Diabetes Prevention and Control: Recommendations from the National Clinical Care Commission - (Peer Reviewed Journal)
Schillinger, D., Bullock, A., Powell, C., Fukagawa, N.K., Greenlee, C., Towne, J., Gonzalvo, J.D., Lopata, A.M., Cook Iv, W.J., Herman, W.H. 2023. Leveraging federal programs for population-level diabetes prevention and control: Recommendations from the National Clinical Care Commission. Diabetes Care. 46(2):e24-e38. https://doi.org/10.2337/dc22-0619.

Valuing the Diversity of Research Methods to Advance Nutrition Science - (Peer Reviewed Journal)
Mattes, R., Rowe, S., Ohlhorst, S., Brown, A., Brown, A., Hoffman, D., Liska, D., Feskens, E., Dhillon, J., Tucker, K., Epstein, L., Neufeld, L., Kelley, M., Fukagawa, N.K. 2022. Valuing the diversity of research methods to advance nutrition science. Advances in Nutrition. https://doi.org/10.1093/advances/nmac043.

Finding a cell-permeable compound to inhibit inflammatory cytokines: Uptake, biotransformation, and anti-cytokine activity of javamide-I/-II esters - (Peer Reviewed Journal)
Park, J.B. 2022. Finding a cell-permeable compound to inhibit inflammatory cytokines: Uptake, biotransformation, and anti-cytokine activity of javamide-I/-II esters. Life Sciences. 291:120280. https://doi.org/10.1016/j.lfs.2021.120280.

In vivo effects of coffee containing javamide-I/-II on body weight, LDL, HDL, total cholesterol, triglycerides, leptin, adiponectin, C-reactive protein, sE-selectin, TNF-alpha, and MCP-1 - (Peer Reviewed Journal)
Park, J.B. 2021. In vivo effects of coffee containing javamide-I/-II on body weight, LDL, HDL, total cholesterol, triglycerides, leptin, adiponectin, C-reactive protein, sE-selectin, TNF-alpha, and MCP-1. Current Developments in Nutrition. 6(1). https://doi.org/10.1093/cdn/nzab145.

Soybean callus - a potential source of tocopherols - (Peer Reviewed Journal)
Muresan, L., Clapa, D., Rusu, T., Wang, T.Y., Park, J.B. 2021. Soybean callus - a potential source of tocopherols. Plants. 10:2571. https://doi.org/10.3390/plants10122571.

Effects of differences in resistant starch content of rice on intestinal microbial composition - (Peer Reviewed Journal)
Wan, J., Wu, Y., Pham, Q., Li, R.W., Yu, L., Chen, M., Boue, S.M., Yokoyama, W., Li, B., Wang, T.T.Y. 2021. Effects of differences in resistant starch content of rice on intestinal microbial composition. Journal of Agricultural and Food Chemistry. 69(28):8017-8027. https://doi.org/10.1021/acs.jafc.0c07887.

Managing Regulatory Requirements in Clinical Nutrition Randomized Controlled Trials: A mini-review and commentary - (Other)

Transcriptomic analysis of Androgen-dependent Human Prostate Cancer LNCaP Cells and its Tumor Xenograft to elucidate the components and mechanisms contributed by tumor environment - (Peer Reviewed Journal)
Yu, L., Li, R.W., Huang, H., Pham, Q., Yu, L., Wang, T.T.Y. 2021. Transcriptomic analysis of LNCaP tumor xenograft to elucidate the components and mechanisms contributed by tumor environment as targets for dietary prostate cancer prevention studies. Nutrients. 13(3):1000. https://doi.org/10.3390/nu13031000.

Disability-adjusted life years (DALYs) due to chronic and hidden hunger under food system evolution with climate change and adaptation to 2050 - (Peer Reviewed Journal)
Fukagawa, N.K., Sulser, T.B., Beach, R., Dunston, S., Wiebe, K. 2021. Disability-adjusted life years (DALYs) due to chronic and hidden hunger under food system evolution with climate change and adaptation to 2050. American Journal of Clinical Nutrition. https://doi.org/10.1093/ajcn/nqab101.

Ultrafine Particles Altered Gut Microbial Population and Metabolic Profiles in a Sex-Specific Manner in an Obese Mouse Model - (Peer Reviewed Journal)
Yang, K., Xu, M., Cao, J., Qi, Z., Rahman, M., Holmen, B.A., Fukagawa, N.K., Zhu, J. 2021. Ultrafine particles altered gut microbial population and metabolic profiles in a sex-specific manner in an obese mouse model. Nature Scientific Reports. 11. Article 6906. https://doi.org/10.1038/s41598-021-85784-4.

Chemical composition of tomato seed flours, and their radical scavenging, anti-inflammatory and gut microbiota modulating properties - (Peer Reviewed Journal)
Choe, U., Sun, J., Bailoni, E., Chen, P., Li, Y., Goa, B., Wang, T.T., Rao, J., Yu, L. 2021. Chemical composition of tomato seed flours, and their radical scavenging, anti-inflammatory and gut microbiota modulating properties. Molecules. 26(5):1478. https://doi.org/10.3390/molecules26051478.

Dietary Indole-3-carbinol alleviated spleen enlargement, enhanced IgG response in C3H/HeN mice infected with Citrobacter rodentium - (Peer Reviewed Journal)
Wu, Y., Wang, J., He, Q., Yu, L., Pham, Q., Cheung, L., Zhang, Z., Kim, Y.S., Smith, A.D., Wang, T.T. 2020. Dietary Indole-3-carbinol alleviated spleen enlargement, enhanced IgG response in C3H/HeN mice infected with Citrobacter rodentium. Nutrients. 12(10)3148. https://doi.org/10.3390/nu12103148.

Potential impacts of soil tillage system on isoflavone concentration of soybean as functional food ingredients - (Peer Reviewed Journal)
Muresan, L., Clapa, D., Borsal, O., Teodor, R., Wang, T.T., Park, J.B. 2020. Potential impacts of soil tillage system on isoflavone concentration of soybean as functional food ingredients. Land. 9(10):386. https://doi.org/10.3390/land9100386.

U.S. Documentation and Regulation of Human Nutrition Randomized Controlled Trials - (Peer Reviewed Journal)
Weaver, C., Fukagawa, N.K., Liska, D., Mattes, R.D., Matuszek, G., Nieves, J.W., Shapses, S.A., Snestelaar, L.G. 2020. U.S. documentation and regulation of human nutrition randomized controlled trials. Advances in Nutrition. https://doi.org/10.1093/advances/nmaa118.

Potential biomarkers for early detection of 3-MCPD dipalmitate exposure in Sprague Dawley rats - (Peer Reviewed Journal)
Huang, G., Wu, Y., Liu, M., Sun, X., Lu, W., Gao, B., Wang, T.T., Yu, L. 2020. Potential biomarkers for early detection of 3-MCPD dipalmitate exposure in Sprague Dawley rats. Journal of Agricultural and Food Chemistry. 68(35):9594-9602. https://doi.org/10.1021/acs.jafc.0c03474.

Kahweol Found in Coffee Inhibits IL-2 Production Via Suppressing the Phosphorylations of ERK and c-Fos in Lymphocytic Jurkat Cells - (Peer Reviewed Journal)
Park, J.B. 2020. Kahweol found in coffee inhibits IL-2 production via suppressing the phosphorylations of ERK and c-Fos in lymphocytic jurkat cells. Journal of Dietary Supplement. 18{1-11). https://doi.org/10.1080/19390211.2020.1784347.

Javamide-II inhibits IL-6 without significant impact on TNF-alpha and IL-1beta in macrophage-like cells - (Peer Reviewed Journal)
Park, J.B., Peters, R.C., Pham, Q., Wang, T.T. 2020. Javamide-II inhibits IL-6 without significant impact on TNF-alpha and IL-1beta in macrophage-like cells. BioMedical Journal. 8(6);138. https://doi.org/10.3390/biomedicines8060138.

Indole-3-carbinol inhibits Citrobacter rodentium infection through multiple pathways including reduction of bacterial adhesion and enhancement of cytotoxic T cell activity - (Peer Reviewed Journal)
Wu, Y., He, Q., Yu, L., Pham, Q., Cheung, L., Kim, Y.S., Wang, T.T., Smith, A.D. 2020. Indole-3-carbinol inhibits Citrobacter rodentium infection through multiple pathways including reduction of bacterial adhesion and enhancement of cytotoxic T cell activity. Nutrients. 12(4):917. https://doi.org/doi: 10.3390/nu12040917.

Chemical composition of cold-pressed blackberry seed flour extract and its potential health-beneficial properties - (Peer Reviewed Journal)
Choe, U., Li, Y., Gao, B., Yu, L., Wang, T.T., Sun, J., Chen, P., Yu, L. 2020. Chemical composition of cold-pressed blackberry seed flour extract and its potential health-beneficial properties. Food Science and Nutrition. 8(2):1215-1225. https://doi.org/10.1002/fsn3.1410.

Dietary fiber isolated from sweet potato residues promotes healthy gut microbiome profile - (Peer Reviewed Journal)
Lu, M., Li, X., Zhou, S., Wang, T.T., Zhou, S., Yang, K., Li, Y., Tian, J., Wang, J. 2020. Dietary fiber isolated from sweet potato residues promotes healthy gut microbiome profile. Food and Function. 11, 689-699. https://doi.org/10.1039/c9fo01009b.

Effects of rice with different amounts of resistant starch on mice fed a high-fat diet: attenuation of adipose weight gain - (Peer Reviewed Journal)
Wan, J., Wu, Y., Pham, Q., Yu, L., Chen, M., Boue, S.M., Yokoyama, W.H., Li, B., Wang, T.T. 2019. Effects of rice with different amounts of resistant starch on mice fed a high-fat diet: attenuation of adipose weight gain. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/acs.jafc.9b05505.

Rice: Importance for Global Nutrition - (Proceedings)
Fukagawa, N.K., Ziska, L.H. 2019. Rice: Importance for Global Nutrition. Journal of Nutritional Science and Vitaminology. 65:S2-S3. https://doi.org/10.3177/jnsv.65.S2.