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ARS Home » Plains Area » College Station, Texas » Southern Plains Agricultural Research Center » Food and Feed Safety Research » Research » Research Project #429791

Research Project: Understanding Salmonella in the Peripheral Lymph Nodes of Cattle and Implementation of Intervention Strategies

Location: Food and Feed Safety Research

Project Number: 3091-32000-033-04-S
Project Type: Non-Assistance Cooperative Agreement

Start Date: Sep 1, 2016
End Date: Aug 31, 2021

Objective:
The objective of the research is to further the understanding of uptake and elimination of Salmonella in the peripheral lymph nodes of cattle, and conduct rapid and well-controlled evaluation of potential intervention strategies designed to prevent Salmonella infection of the lymph node or promote its elimination.

Approach:
New methods of experimental inoculation of the peripheral lymph nodes (PLN), developed at Texas Tech University, will be examined against current USDA methods. The best inoculation techniques will then be used to further the understanding of the uptake of Salmonella by the PLN and evaluate factors affecting this uptake, such as hormones produced in response to seasonal changes and stress. Further potential evaluation strategies will also be screened prior to field studies.