Research Project: Developing Mitigation Strategies for Poisonous Plants in Livestock Production Systems

Location: Poisonous Plant Research

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Geography and admixture shape the genome-scale phylogeny of North American Delphinium - (Peer Reviewed Journal)

Herbicide treatment of previously seeded rangeland on the Channeled Scablands of eastern Washington with indaziflam and imazapic - (Abstract Only)

Is hemp (Cannabis sativa) safe to feed pregnant sheep? - (Peer Reviewed Journal)
Green, B.T., Gardner, D.R., Stonecipher, C.A., Welch, K.D., Lee, S.T., Sullivan, T., Westmoreland, F.M., Cook, D. 2025. Is hemp (Cannabis sativa) safe to feed pregnant sheep?. Translational Animal Science. 9. Article txaf093. https://doi.org/10.1093/tas/txaf093.

An evaluation of the toxic norditerpenoid alkaloid content across Delphinium species, and their acute toxicities in a murine model - (Peer Reviewed Journal)
Welch, K.D., Gardner, D.R., Cook, D., Lee, S.T., Stonecipher, C.A., Green, B.T. 2025. An evaluation of the toxic norditerpenoid alkaloid content across Delphinium species, and their acute toxicities in a murine model. Chemistry and Biodiversity. Article e00779. https://doi.org/10.1002/cbdv.202500779.

Senecio pampeanus poisoning in beef cattle: Case report and toxicological evaluation - (Peer Reviewed Journal)
Ovelar, M.F., Garcia, J.A., Cook, D., Gardner, D., Stegelmeier, B.L., Diez de Ulzurrun, P., Tettamanti, A., Balbuena, D., Lita, E.V., Poo, J.I., Scioli, M.V., Canton, G.J. 2025. Senecio pampeanus poisoning in beef cattle: Case report and toxicological evaluation. Veterinary Research Communications. 49. Article 205. https://doi.org/10.1007/s11259-025-10768-y.

Evaluation of herbicides for Geyer larkspur (Delphinium geyeri) - (Peer Reviewed Journal)
Stonecipher, C.A., Welch, K.D., Derner, J.D., Gardner, D.R., Ransom, C., Cook, D. 2025. Evaluation of herbicides for Geyer larkspur (Delphinium geyeri). Weed Technology. 39. Article e72. https://doi.org/10.1017/wet.2025.35.

Oxalate nephropathy in cattle associated with the consumption of Megathyrsus maximus in Argentina - (Peer Reviewed Journal)
Avellaneda-Caceres, A., Lee, S.T., Ruiz, A., Sandoval, G.V., Colque-Caro, L.A., Cook, D., Aguirre, L.S., Uzal, F.A., Micheloud, J.F. 2025. Oxalate nephropathy in cattle associated with the consumption of Megathyrsus maximus in Argentina. Journal of Veterinary Diagnostic Investigation. https://doi.org/10.1177/10406387251336265.

Two unique cases of ponderosa pine needle-induced abortions - (Peer Reviewed Journal)
Welch, K.D., Dietz, M.A., Edmonds, S.E., Gardner, D.R., Cook, D. 2025. Two unique cases of ponderosa pine needle-induced abortions. Poisonous Plant Research. 8:23-28. https://doi.org/10.26077/a65e-3a11.

A case of milkweed poisoning in cattle in Colorado - (Peer Reviewed Journal)
Walck, R., Webb, B., Ensley, S., Cook, D. 2025. A case of milkweed poisoning in cattle in Colorado. Poisonous Plant Research. 8:31-36. https://doi.org/10.26077/13yr-nf86.

DNA data (genome skims and metabarcodes) paired with chemical data demonstrate utility for retrospective analysis of forage linked to fatal poisoning of cattle - (Peer Reviewed Journal)
Cook, D., Kocurek, B., Stonecipher, C.A., Welch, K.D., Gardner, D.R., Mammel, M., Reed, E., Ramachandran, P., Erickson, D., Commichaux, S., Ottesen, A. 2025. DNA data (genome skims and metabarcodes) paired with chemical data demonstrate utility for retrospective analysis of forage linked to fatal poisoning of cattle. Toxicon. 256. Article 108285. https://doi.org/10.1016/j.toxicon.2025.108285.

The rodent electronic nicotine delivery system: Apparatus for voluntary nose-only e-cigarette aerosol inhalation - (Peer Reviewed Journal)
Odum, A.L., Willis-Moore, M.E., Callister, K.T., Haynes, J.M., Frye, C.C.J., Scribner, L.N., Legaspi, D.N., Santos Da Silva, D., Olsen, A.L., Truscott, T.T., Alden, P.T., Bevins, R.A., Leventhal, A.M., Lee, S.T., Gomer, B., Benninghoff, A.D. 2025. The rodent electronic nicotine delivery system: Apparatus for voluntary nose-only e-cigarette aerosol inhalation. Journal of the Experimental Analysis of Behavior. 123(2):337-354. https://doi.org/10.1002/jeab.70005.

Intoxication of sheep by Astragalus arequipensis in northwestern Argentina - (Peer Reviewed Journal)
Marin, R.E., Gardner, D., Cook, D., Armien, A.G., Fortunato, R.H., Riet-Correa, F., Uzal, F.A. 2025. Intoxication of sheep by Astragalus arequipensis in northwestern Argentina. Journal of Veterinary Diagnostic Investigation. 37(2):375-379. https://doi.org/10.1177/10406387241311815.

Halogeton and greasewood poisoning in cattle and sheep in Utah - (Peer Reviewed Journal)
Kelly, E.J., Lee, S.T., Brown, A., Cook, D. 2025. Halogeton and greasewood poisoning in cattle and sheep in Utah. Poisonous Plant Research. 8:3-6. https://doi.org/10.26077/bd54-998b.

A review of intermittent poisoning to mitigate toxic plant-induced disease in livestock - (Review Article)
Stegelmeier, B.L., Davis, T.Z., Panter, K.E., Welch, K.D., Knoppel, E.L. 2024. A review of intermittent poisoning to mitigate toxic plant-induced disease in livestock. Veterinary Sciences. 12(1). Article 13. https://doi.org/10.3390/vetsci12010013.

A case of dallisgrass staggers in Oklahoma - (Peer Reviewed Journal)
Lee, S.T., Ozuna, G.C., Villasenor, A., Cook, D. 2024. A case of dallisgrass staggers in Oklahoma. Poisonous Plant Research. 7:29-33. https://doi.org/10.26077/256c-1d01.

The evaluation of earwax as a noninvasive specimen to determine livestock exposure to death camas (Zigadenus paniculatus) - (Peer Reviewed Journal)
Lee, S.T., Stonecipher, C.A., Welch, K.D., Cook, D. 2024. The evaluation of earwax as a noninvasive specimen to determine livestock exposure to death camas (Zigadenus paniculatus). Toxicon. 252. Article 108181. https://doi.org/10.1016/j.toxicon.2024.108181.

The actions of varenicline on alkaloids from Conium maculatum (poison hemlock), Lupinus sulphureus (sulphur lupine) and Nicotiana glauca (tree tobacco) - (Peer Reviewed Journal)
Green, B.T., Lee, S.T., Welch, K.D., Cook, D., Stonecipher, C.A. 2024. The actions of varenicline on alkaloids from Conium maculatum (poison hemlock), Lupinus sulphureus (sulphur lupine) and Nicotiana glauca (tree tobacco). Toxicon. 252. Article 108184. https://doi.org/10.1016/j.toxicon.2024.108184.

Case report: Investigating an outbreak of tremorgenic mycotoxicosis in beef cows on pasture in Mississippi due to ergot (Claviceps paspali) infection in dallisgrass (Paspalum dilatatum) - (Peer Reviewed Journal)
Jumper, W.I., Brown, C.C., Lee, S.T., Cook, D., Stilwell, J.M., Harvey, K.M. 2024. Case report: Investigating an outbreak of tremorgenic mycotoxicosis in beef cows on pasture in Mississippi due to ergot (Claviceps paspali) infection in dallisgrass (Paspalum dilatatum). Bovine Practitioner Journal. 58(2):59-68. https://doi.org/10.21423/bpj20249035.

The use of earwax to determine livestock exposure to teratogenic lupine - (Peer Reviewed Journal)
Stonecipher, C.A., Lee, S.T., Welch, K.D., Valles, K.R., Cook, D. 2024. The use of earwax to determine livestock exposure to teratogenic lupine. Toxicon. 248. Article 108053. https://doi.org/10.1016/j.toxicon.2024.108053.

Comparison of the acute toxicity of zygacine versus zygadenine - (Peer Reviewed Journal)
Welch, K.D., Gardner, D.R., Lee, S.T., Stonecipher, C.A., Cook, D. 2024. Comparison of the acute toxicity of zygacine versus zygadenine. Toxicon. 248. Article 108037. https://doi.org/10.1016/j.toxicon.2024.108037.

Extensive local geographic variation in locoweed toxin produced by a fungal endophyte - (Peer Reviewed Journal)
Davis, J.S., Scott, M., Cook, D., Gardner, D., Morse, G., Grillo, M. 2024. Extensive local geographic variation in locoweed toxin produced by a fungal endophyte. Journal of Chemical Ecology. 50:465-477. https://doi.org/10.1007/s10886-024-01529-3.

Comparison of sheep and goats to the acute toxic effects of foothill death camas - (Peer Reviewed Journal)
Welch, K.D., Lee, S.T., Stonecipher, C.A., Gardner, D., Cook, D. 2024. Comparison of sheep and goats to the acute toxic effects of foothill death camas. Poisonous Plant Research. 7:17-26. https://doi.org/10.26077/c444-bc12.

A review on mycotoxins and mycotoxicoses in ruminants and Equidae in South America - (Review Article)
Riet-Correa, F., Cook, D., Micheloud, J.F., Machado, M., Mendonca, F.S., Schild, A.L., Lemos, R.A. 2024. A review on mycotoxins and mycotoxicoses in ruminants and Equidae in South America. Toxicon. 247. Article 107827. https://doi.org/10.1016/j.toxicon.2024.107827.

Toxicosis from range lupine ingestion in a research herd of Rafter 7 Merino sheep - (Peer Reviewed Journal)
Weigler, B.J., Mandeville, W.F., Huber, S., Mccuin, G., Cartagena, F., Cook, D., Lee, S.T., Pritsos, C.A. 2024. Toxicosis from range lupine ingestion in a research herd of Rafter 7 Merino sheep. Poisonous Plant Research. 7:10-14. https://doi.org/10.26077/1a49-f0ef.

Japanese Yew (Taxus) poisoning of wild ungulates in Utah during the winter of 2022-2023 - (Peer Reviewed Journal)
Lee, S.T., Kelly, J., Stout, V., Lamb, S., Baldwin, T.J., Cook, D. 2024. Japanese Yew (Taxus) poisoning of wild ungulates in Utah during the winter of 2022-2023. Toxicon. 246. Article 107779. https://doi.org/10.1016/j.toxicon.2024.107779.

Cattle toxicity from woolly locoweed (Astragalus mollissimus): a case study in central New Mexico - (Peer Reviewed Journal)
Spackman, C., Stonecipher, C.A., Cook, D. 2024. Cattle toxicity from woolly locoweed (Astragalus mollissimus): a case study in central New Mexico. Poisonous Plant Research. 7:3-7.

Lupine-induced crooked calf syndrome: Mitigation through intermittent grazing management of cattle - (Peer Reviewed Journal)
Welch, K.D., Lee, S.T., Panter, K.E., Stegelmeier, B.L., Stonecipher, C.A., Cook, D. 2024. Lupine-induced crooked calf syndrome: Mitigation through intermittent grazing management of cattle. Translational Animal Science. 8. Article txae079. https://doi.org/10.1093/tas/txae079.

Acute death as a result of poisoning tropical (Bos taurus indicus) but not temperate (Bos taurus taurus) cattle after oral dosing with Lupinus leucophyllus (velvet lupine) - (Peer Reviewed Journal)
Green, B.T., Welch, K.D., Lee, S.T., Davis, T.Z., Stonecipher, C.A., Stegelmeier, B.L., Cook, D. 2024. Acute death as a result of poisoning tropical (Bos taurus indicus) but not temperate (Bos taurus taurus) cattle after oral dosing with Lupinus leucophyllus (velvet lupine). Toxicon. 242. Article 107706. https://doi.org/10.1016/j.toxicon.2024.107706.

Analysis of the mycotoxin levels and expression pattern of SWN genes at different time points in the fungus Slafractonia leguminicola - (Peer Reviewed Journal)
Das, S., Gardner, D.R., Cook, D., Creamer, R. 2024. Analysis of the mycotoxin levels and expression pattern of SWN genes at different time points in the fungus Slafractonia leguminicola. Microorganisms. 12(4). Article 670. https://doi.org/10.3390/microorganisms12040670.

Evaluation of the toxicological effects of Neltuma alpataco (Prosopis alpataco) pod alkaloid extract - (Peer Reviewed Journal)
Cholich, L., Pistan, M., Benitez, A.C., Torres, A., Garcia, E.N., Martinez, A., Gardner, D., Bustillo, S. 2024. Evaluation of the toxicological effects of Neltuma alpataco (Prosopis alpataco) pod alkaloid extract. Toxicon. 241. Article 107665. https://doi.org/10.1016/j.toxicon.2024.107665.

Supplementation with increasing doses of selenium associated with vitamin E in the treatment of bovines with enzootic hematuria - (Peer Reviewed Journal)
Moreira Jr., C.A., Oliveira, E.V., Cardoso, C.A., Miranda, M.B., Guedes, N.A., Burak, D.L., Pfister, J.A., Nunes, L.C. 2024. Supplementation with increasing doses of selenium associated with vitamin E in the treatment of bovines with enzootic hematuria. Pesquisa Veterinaria Brasileira. 44: Article e07349. https://doi.org/10.1590/1678-5150-PVB-7349.

Multiomics reveals mechanisms of Alternaria oxytropis inhibiting pathogenic fungi in Oxytropis ochrocephala - (Peer Reviewed Journal)
Fu, K., Schardl, C.L., Cook, D., Cao, X., Ling, N., He, C., Wu, D., Xue, L., Li, Y., Shi, Z. 2024. Multiomics reveals mechanisms of Alternaria oxytropis inhibiting pathogenic fungi in Oxytropis ochrocephala. Journal of Agricultural and Food Chemistry. 72(4):2397-2409. https://doi.org/10.1021/acs.jafc.3c09049.

Potential toxic effects produced by L-mimosine in the thyroid and reproductive systems. Evaluation in male rats - (Peer Reviewed Journal)
Gotardo, A.T., Dipe, V.V., de Almeida, E.R.M., Hueza, I.M., Pfister, J.A., Gorniak, S.L. 2021. Potential toxic effects produced by L-mimosine in the thyroid and reproductive systems. Evaluation in male rats. Toxicon. 203:121-128. https://doi.org/10.1016/j.toxicon.2021.10.003.