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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Virus and Prion Research » Research » Research Project #440677

Research Project: Elucidating the Pathobiology and Transmission of Transmissible Spongiform Encephalopathies

Location: Virus and Prion Research

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

The effect on prion incubation period after inoculation with dilutions within the dynamic range of ELISA absorbance - (Peer Reviewed Journal)

Combinatorial treatment of brain samples from sheep with scrapie using sodium percarbonate, sodium dodecyl sulfate, and proteinase K increases survival time in inoculated susceptible sheep Reprint Icon - (Peer Reviewed Journal)
Harm, T.A., Smith, J.D., Cassmann, E.D., Greenlee, J.J. 2022. Combinatorial treatment of brain samples from sheep with scrapie using sodium percarbonate, sodium dodecyl sulfate, and proteinase K increases survival time in inoculated susceptible sheep. Research in Veterinary Science. 152:497-503. https://doi.org/10.1016/j.rvsc.2022.09.002.

Comparison of protein hallmarks of ferroptosis in mice with prion disease - (Abstract Only)

Transmission of raccoon passaged chronic wasting disease agent to white-tailed deer Reprint Icon - (Peer Reviewed Journal)
Cassmann, E.D., Frese, A.J., Moore, S.J., Greenlee, J.J. 2022. Transmission of raccoon passaged chronic wasting disease agent to white-tailed deer. Viruses. 14(7). Article 1578. https://doi.org/10.3390/v14071578.

Exploring the possibility of CWD transmission through artificial insemination of semen from CWD positive bucks - (Trade Journal)
Cassmann, E.D., Greenlee, J.J. 2022. Exploring the possibility of CWD transmission through artificial insemination of semen from CWD positive bucks. North American Deer Farmer. p. 107-109.

Cattle with the EK211 PRNP polymorphism are susceptible to the H-type bovine spongiform encephalopathy agent from either E211K or wild type donors after oronasal inoculation Reprint Icon - (Abstract Only)
Greenlee, J.J., Cassmann, E.D., Moore, S., West Greenlee, H.M. 2022. Cattle with the EK211 PRNP polymorphism are susceptible to the H-type bovine spongiform encephalopathy agent from either E211K or wild type donors after oronasal inoculation. Prion 2022 Conference abstracts: pushing the boundaries. 16(1):150. https://doi.org/10.1080/19336896.2022.2091286.

Application of PMCA to understand CWD prion strains, species barrier and zoonotic potential Reprint Icon - (Abstract Only)
Pritzkow, S., Gorski, D., Ramirez, F., Wang, F., Telling, G.C., Greenlee, J.J., Benestad, S.L., Soto, C. 2022. Application of PMCA to understand CWD prion strains, species barrier and zoonotic potential. Prion 2022 Conference abstracts: pushing the boundaries. 16(1):209. https://doi.org/10.1080/19336896.2022.2091286.

ATYPRION project: assessing the zoonotic potential of interspecies transmission of CWD isolates to livestock (preliminary results) Reprint Icon - (Abstract Only)
Vidal, E., Espinosa, J., Giler, S., Ordonez, M., Cantero, G., Beringue, V., Greenlee, J.J., Torres, J. 2022. ATYPRION project: assessing the zoonotic potential of interspecies transmission of CWD isolates to livestock (preliminary results). Prion 2022 Conference abstracts: pushing the boundaries. 16(1):240. https://doi.org/10.1080/19336896.2022.2091286.

Generation of human chronic wasting disease in transgenic mice Reprint Icon - (Abstract Only)
Wang, Z., Qin, K., Camacho, M.V., Cali, I., Yuan, J., Shen, P., Gilliland, T., Shah, S., Gerasimenko, M., Tang, M., Rajamanickam, S., Yadati, A., Schonberger, L.B., Greenlee, J.J., Kong, Q., Mastrianni, J.A., Zou, W. 2022. Generation of human chronic wasting disease in transgenic mice. Prion 2022 Conference abstracts: pushing the boundaries. 16(1):243. https://doi.org/10.1080/19336896.2022.2091286.

The chronic wasting disease agent from white-tailed deer is highly infectious to humanized mice after passage through raccoons Reprint Icon - (Abstract Only)
Cassmann, E.D., Qi, X., Kong, Q., Greenlee, J.J. 2022. The chronic wasting disease agent from white-tailed deer is highly infectious to humanized mice after passage through raccoons. Prion 2022 Conference abstracts: pushing the boundaries. 16(1):120. https://doi.org/10.1080/19336896.2022.2091286.

The chronic wasting disease agent from white-tailed deer fails to adapt to sheep upon second passage Reprint Icon - (Abstract Only)
Frese, A.J., Cassmann, E.D., West Greenlee, H.M., Greenlee, J.J. 2022. The chronic wasting disease agent from white-tailed deer fails to adapt to sheep upon second passage. Prion 2022 Conference abstracts: pushing the boundaries. 16(1):144. https://doi.org/10.1080/19336896.2022.2091286.

Second passage of scrapie in white-tailed deer is discernable from chronic wasting disease Reprint Icon - (Abstract Only)
Lambert, Z., West Greenlee, H.M., Cassmann, E.D., Greenlee, J.J. 2022. Second passage of scrapie in white-tailed deer is discernable from chronic wasting disease. Prion 2022 Conference abstracts: pushing the boundaries. 16(1):181. https://doi.org/10.1080/19336896.2022.2091286.

Generation of human chronic wasting disease in transgenic mice - (Proceedings)
Wang, Z., Qin, K., Camacho, M.V., Cali, I., Yuan, J., Shen, P., Greenlee, J.J., Kong, Q., Mastrianni, J.A., Zou, W. 2022. Generation of human chronic wasting disease in transgenic mice. Proceedings of 10th Iberian Congress on Prions, May 19-20, 2022, Vila Real, Portugal.

Differential accumulation of misfolded prion strains in natural hosts of prion diseases Reprint Icon - (Review Article)
Lambert, Z., Greenlee, J.J., Cassmann, E.D., West Greenlee, H.M. 2021. Differential accumulation of misfolded prion strains in natural hosts of prion diseases. Viruses. 13(12). Article 2453. https://doi.org/10.3390/v13122453.

Attempted transmission of the CWD agent to deer with potentially resistant prion protein genotypes - (Trade Journal)
Greenlee, J.J., Cassmann, E.D. 2022. Attempted transmission of the CWD agent to deer with potentially resistant prion protein genotypes. North American Deer Farmer. p. 117.