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ARS Home » Midwest Area » Ames, Iowa » National Laboratory for Agriculture and The Environment » Agroecosystems Management Research » Research » Research Project #437440

Research Project: Inherent Variation in Oxidative Stress Measures in Breeding and Lactating Gilts and Correlation to Measures of Sow Lifetime Productivity

Location: Agroecosystems Management Research

Project Number: 5030-31000-006-51-T
Project Type: Trust Fund Cooperative Agreement

Start Date: Jul 1, 2020
End Date: Jul 31, 2022

Objective:
Determine the inherent variation in oxidative stress measures in gestating and lactating sows, and correlation to measures of sow lifetime productivity.

Approach:
Three groups of parity 0 gilts (60 each) will be evaluated for oxidative stress by obtaining blood at four critical periods during gestation and lactation: day 45 (baseline measures of oxidative stress status and confirmed pregnant), day -5 farrowing (critical time due to lowest reported alpha-tocopherol and highest reported DNA damage), day +5 farrowing (critical time relative to potential sow death loss during farrowing), and day +5 weaning (critical time relative to rebreeding). Each of these 60 sows will then be re-sampled at these same reproductive timepoints during the next two parities. Plasma will be measured for reactive oxygen species and antioxidant capacity using commercially available assay kits. All oxidative stress data will then be related to various measures of sow lifetime productivity.