Research Project: Improving Public Health by Understanding Metabolic and Bio-Behavioral Effects of Following Recommendations in the Dietary Guidelines for Americans

Location: Obesity and Metabolism Research

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans - (Peer Reviewed Journal)
U-Din, M., De Mello, V.D., Tuomainen, M., Raiko, J., Niemi, T., Fromme, T., Klavus, A., Gautier, N., Haimilahti, K., Lehtonen, M., Kristiansen, K., Newman, J.W., Pietiläinen, K.H., Pihlajamäki, J., Amri, E., Klingenspor, M., Nuutila, P., Pirinen, E., Hanhineva, K., Virtanen, K.A. 2023. Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans. Cell Reports. 42(9). https://doi.org/10.1016/j.celrep.2023.113131.

The effects of prenatal and postnatal high-dose vitamin B-12 supplementation on human milk vitamin B-12: a randomized, double-blind, placebo-controlled trial in Tanzania - (Peer Reviewed Journal)
Wand, D., Shahab-Ferdows, S., Lweno, O.N., Hampel, D., Method, B., Yelverton, C.A., Nguyen, C.H., Aboud, S., Allen, L.H., Fawzi, W.W. 2023. The effects of prenatal and postnatal high-dose vitamin B-12 supplementation on human milk vitamin B-12: a randomized, double-blind, placebo-controlled trial in Tanzania. The American Journal of Clinical Nutrition. https://doi.org/10.1016/j.ajcnut.2023.07.023.

Adipocytes reprogram cancer cell metabolism by diverting glucose towards glycerol-3-phosphate thereby promoting metastasis - (Peer Reviewed Journal)
Mukherjee, A., Bezwada, D., Greco, F., Zandbergen, M., Shen, T., Chiang, C., Tasdemir, M., Fahrmann, J., Grapov, D., La Frano, M.R., Vu, H.S., Faubert, B., Newman, J.W., Mcdonnell, L.A., Nezi, L., Fiehn, O., Deberardinis, R., Lengyel, E. 2023. Adipocytes reprogram cancer cell metabolism by diverting glucose towards glycerol-3-phosphate thereby promoting metastasis. Cell Metabolism. https://doi.org/10.1038/s42255-023-00879-8.

Tai Chi exercise reduces circulating levels of inflammatory oxylipins in postmenopausal women with knee osteoarthritis: results from a pilot study - (Peer Reviewed Journal)
Shen, C., Newman, J.W., Elmassry, M.M., Borkowski, K., Chyu, M., Kahathuduwa, C., Neugebauer, V., Watkins, B.A. 2023. Tai Chi exercise reduces circulating levels of inflammatory oxylipins in postmenopausal women with knee osteoarthritis: results from a pilot study. Frontiers in Medicine. 10. https://doi.org/10.3389/fmed.2023.1210170.

The impacts of slc19a3 deletion and intestinal SLC19A3 insertion on thiamine distribution and brain metabolism in the mouse - (Peer Reviewed Journal)
Wen, A., Zhu, Y., Yee, S., Park, B., Giacomini, K.M., Greenberg, A.S., Newman, J.W. 2023. The impacts of slc19a3 deletion and intestinal SLC19A3 insertion on thiamine distribution and brain metabolism in the mouse. Metabolites. https://doi.org/10.3390/metabo13080885.

Human milk macronutrients and child growth and body composition in the first 2 years: a systematic review - (Peer Reviewed Journal)
Reyes, S.M., Brockway, M., Mcdermid, J.M., Chan, D., Granger, M., Refvik, R., Sidhu, K., Musse, S., Monnin, C., Lotoski, L., Geddes, D., Jehan, F., Kolsteren, P., Allen, L.H., Hampel, D., Eriksen, K.G., Rodriguez, N., Azad, M.B. 2023. Human milk macronutrients and child growth and body composition in the first 2 years: a systematic review. Advances in Nutrition. https://doi.org/10.1016/j.advnut.2023.06.005.

Dietary docosahexaenoic acid and glucose systemic metabolic changes in the mouse - (Peer Reviewed Journal)
Watkins, B., Newman, J.W., Kuchel, G.A., Fiehn, O., Kim, J. 2023. Dietary docosahexaenoic acid and glucose systemic metabolic changes in the mouse. Nutrients. 15(12). Article 2679. https://doi.org/10.3390/nu15122679.

Analysis of strain, sex, and diet-dependent modulation of gut microbiota reveals candidate keystone organisms driving microbial diversity in response to American and ketogenic diets - (Peer Reviewed Journal)
Salvador, A.C., Huda, N.M., Arends, D., Elsaddi, A.M., Gacasan, A.C., Brockmann, G.A., Valdar, W., Bennett, B.J., Threadgill, D.W. 2023. Analysis of strain, sex, and diet-dependent modulation of gut microbiota reveals candidate keystone organisms driving microbial diversity in response to American and ketogenic diets. Microbiome. 11(220). https://doi.org/10.1186/s40168-023-01588-w.

Integrative analysis of hepatic transcriptional profiles reveals genetic regulation of atherosclerosis in hyperlipidemic Diversity Outbred-F1 mice - (Peer Reviewed Journal)
Kim, M., Huda, N., Evans, L.W., Que, E., Gertz, E.R., Maeda-Smithies, N., Bennett, B.J. 2023. Integrative analysis of hepatic transcriptional profiles reveals genetic regulation of atherosclerosis in hyperlipidemic Diversity Outbred-F1 mice. Scientific Reports. 13. Article 9475. https://doi.org/10.1038/s41598-023-35917-8.

Improving anemia assessment in clinical and public health settings - (Peer Reviewed Journal)
Williams, A.M., Brown, K.H., Allen, L.H., Dary, O., Rawat, R., Moorthy, D., Suchdev, P.S. 2023. Improving anemia assessment in clinical and public health settings. Journal of Nutrition. https://doi.org/10.1016/j.tjnut.2023.05.032.

The effect of trimethoprim on thiamine absorption: A transporter-mediated drug-nutrient interaction - (Peer Reviewed Journal)
Vora, B., Wen, A., Yee, S., Trinh, K., Azimi, M., Green, E.A., Sirota, M., Greenberg, A.S., Newman, J.W., Giacomini, K.M. 2023. The effect of trimethoprim on thiamine absorption: A transporter-mediated drug-nutrient interaction. Clinical Pharmacology and Therapeutics. 114(2):381-392. https://doi.org/10.1002/cpt.2932.

Randomized crossover clinical trial of coenzyme Q10 and nicotinamide riboside in chronic kidney disease - (Peer Reviewed Journal)
Ahmadi, A., Begue, G., Valencia, A.P., Norman, J.E., Lidgard, B., Bennett, B.J., Van Doren, M.P., Marcinek, D.J., Fan, S., Prince, D.K., Gamboa, J., Himmelfarb, J., De Boer, I.H., Kestenbaum, B.R., Roshanravan, B. 2023. Randomized crossover clinical trial of coenzyme Q10 and nicotinamide riboside in chronic kidney disease. Journal of Clinical Investigation. 8(11). Article e167274. https://doi.org/10.1172/jci.insight.167274.

Several serum lipid metabolites are associated with relapse risk in pediatric-onset multiple sclerosis - (Peer Reviewed Journal)
Virupakshaiah, A., Ladakis, D., Nourbakhsh, B., Bhargava, P., Dilwali, S., Schoeps, V., Borkowski, K., Newman, J.W., Waubant, E. 2023. Several serum lipid metabolites are associated with relapse risk in pediatric-onset multiple sclerosis. Multiple Sclerosis Journal. 29(8). https://doi.org/10.1177/13524585231171517.

Investigating donor human milk composition globally to develop effective strategies for the nutritional care of preterm infants: Study protocol - (Peer Reviewed Journal)
Perrin, M.T., Mansen, K., Israel-Ballard, K., Richter, S., Bode, L., Hampel, D., Shahab-Ferdows, S., Allen, L.H., Cofre Maggio, F., Njuguna, E., Tran, H., Wesolowska, A. 2023. Investigating donor human milk composition globally to develop effective strategies for the nutritional care of preterm infants: Study protocol. PLOS ONE. 18(4). Article e0283846. https://doi.org/10.1371/journal.pone.0283846.

Chow diet in mouse aging studies: Nothing regular about it - (Review Article)
Lee, J., Purello, C., Booth, S.L., Bennett, B.J., Wiley, C., Korstanje, R. 2023. Chow diet in mouse aging studies: Nothing regular about it. GeroScience. 45:2079-2084. https://doi.org/10.1007/s11357-023-00775-9.

Prospective placebo-controlled assessment of spore-based probiotic supplementation on sebum production, skin barrier function, and acne - (Peer Reviewed Journal)
Rybak, I., Haas, K., Dhaliwal, S., Burney, W., Pourang, A., Sandhu, S.S., Maloh, J., Newman, J.W., Crawford, R., Sivamani, R.K. 2023. Prospective placebo-controlled assessment of spore-based probiotic supplementation on sebum production, skin barrier function, and acne. Journal of Clinical Medicine. 12(3). Article 895. https://doi.org/10.3390/jcm12030895.

Trimethylamine N-Oxide response to a mixed macronutrient tolerance test in a cohort of United States adults - (Peer Reviewed Journal)
James, K.L., Gertz, E.R., Kirschke-Schneide, C.P., Allayee, H., Huang, L., Kable, M.E., Newman, J.W., Stephensen, C.B., Bennett, B.J. 2023. Trimethylamine N-Oxide response to a mixed macronutrient tolerance test in a cohort of United States adults. International Journal of Molecular Sciences. 24(3). Article 2074. https://doi.org/10.3390/ijms24032074.

The association between plasma choline, growth and neurodevelopment among Malawian children aged 6-15 months enrolled in an egg intervention trial - (Peer Reviewed Journal)
Bragg, M., Prado, E., Caswell, B.L., Arnold, C., George, M., Oakes, L., Beckner, A., DeBolt, M., Bennett, B.J., Maleta, K., Stewart, C. 2022. The association between plasma choline, growth and neurodevelopment among Malawian children aged 6-15 months enrolled in an egg intervention trial. Maternal and Child Nutrition. 19(2). Article e13471. https://doi.org/10.1111/mcn.13471.

Editorial: Postprandial physiology - (Other)
Fiamonici, J., Newman, J.W., Brennan, L. 2022. Editorial: Postprandial physiology. Frontiers in Nutrition. 9. https://doi.org/10.3389/fnut.2022.1107480.

Ecologies, synergies, and biological systems shaping human milk composition—a report from Breastmilk Ecology and the Genesis of Infant Nutrition (BEGIN) Working Group 2 - (Peer Reviewed Journal)

Associations between maternal adiposity and appetite-regulating hormones in human milk are mediated through maternal circulating concentrations and might affect infant outcomes - (Peer Reviewed Journal)
Christensen, S.H., Lewis, J.I., Larnkjær, A., Frøkiær, H., Allen, L.H., Mølgaard, C., Michaelsen, K.F. 2022. Associations between maternal adiposity and appetite-regulating hormones in human milk are mediated through maternal circulating concentrations and might affect infant outcomes. Frontiers in Nutrition. 9. Article 1025439. https://doi.org/10.3389/fnut.2022.1025439.

Metabolite patterns associated with individual response to supervised exercise therapy in patients with intermittent claudication - (Peer Reviewed Journal)
Bellomo, T.R., Tsao, N.L., Johnston-Cox, H., Borkowski, K., Shakt, G., Judy, R., Moore, J., Ratcliffe, S., Fiehn, O., Floyd, T.F., Wehrli, F.W., Mohler, E., Newman, J.W., Damrauer, S.M. 2022. Metabolite patterns associated with individual response to supervised exercise therapy in patients with intermittent claudication. Journal of Vascular Science. 3:379-388. https://doi.org/10.1016/j.jvssci.2022.10.002.

The plasma oxylipin signature provides a deep phenotyping of metabolic syndrome complementary to the clinical criteria - (Peer Reviewed Journal)
Dalle, C., Tournayre, J., Mainka, M., Basiak-Rasala, A., Pétéra, M., Lefèvre-Arbogast, S., Dalloux-Chioccioli, J., Deschasaux-Tanguy, M., Lecuyer, L., Kesse-Guyot, E., Fezeu, L., Hercberg, S., Galan, P., Samieri, C., Zatonska, K., Calder, P.C., Hjorth, M., Astrup, A., Mazur, A., Bertand-Michel, J., Schebb, N.H., Szuba, A., Touvier, M., Newman, J.W., Gladine, C. 2022. The plasma oxylipin signature provides a deep phenotyping of metabolic syndrome complementary to the clinical criteria. International Journal of Molecular Sciences. 23(19). Article 11688. https://doi.org/10.3390/ijms231911688.

Adequate vitamin B12 and folate status of Norwegian vegans and vegetarians - (Peer Reviewed Journal)
Henjum, S., Groufh-Jacobsen, S., Allen, L.H., Raael, E., Israelsson, A., Shahab-Ferdows, S., Hampel, D. 2022. Adequate vitamin B12 and folate status of Norwegian vegans and vegetarians. British Journal of Nutrition. 129(12):2076-2083. https://doi.org/10.1017/S0007114522002987.

Increased risk of preterm delivery with high cortisol during pregnancy is modified by fetal sex: A cohort study - (Peer Reviewed Journal)
Oaks, B., Adu-Afarwuah, S., Ashorn, P., Larty, A., Laugero, K.D., Okronipa, H., Stewart, C., Dewey, K. 2022. Increased risk of preterm delivery with high cortisol during pregnancy is modified by fetal sex: A cohort study. BMC Pregnancy & Childbirth. 22. Article 727. https://doi.org/10.1186/s12884-022-05061-8.

Potential cardioprotective effects and lipid mediator differences in long-chain omega-3 polyunsaturated fatty acid supplemented mice given chemotherapy - (Peer Reviewed Journal)
Angelotti, A., Snoke, D., Ormiston, K., Cole, R., Borkowski, K., Newman, J.W., Orchard, T., Belury, M.A. 2022. Potential cardioprotective effects and lipid mediator differences in long-chain omega-3 polyunsaturated fatty acid supplemented mice given chemotherapy. Metabolites. 12(9). Article 782. https://doi.org/10.3390/metabo12090782.

Linoleate-rich safflower oil diet increases linoleate-derived bioactive lipid mediators in plasma, and brown and white adipose depots of healthy mice - (Peer Reviewed Journal)
Snoke, D., Angelotti, A., Borkowski, K., Cole, R., Newman, J.W., Belury, M.A. 2022. Linoleate-rich safflower oil diet increases linoleate-derived bioactive lipid mediators in plasma, and brown and white adipose depots of healthy mice. Metabolites. 12(8). Article 743. https://doi.org/10.3390/metabo12080743.

Gut microbiota and host genetics modulate the effect of diverse diet patterns on metabolic health - (Peer Reviewed Journal)
Huda, M.N., Salvador, A.C., Barrington, W.T., Gacasan, C.A., D'Souza, E.M., Deus Ramirez, L., Threadgill, D.W., Bennett, B.J. 2022. Gut microbiota and host genetics modulate the effect of diverse diet patterns on metabolic health. Frontiers in Nutrition. 9. Article 896348. https://doi.org/10.3389/fnut.2022.896348.

Altered macronutrient composition and genetics influence the complex transcriptional network associated with adiposity in the Collaborative Cross - (Peer Reviewed Journal)
Yam, P., VerHague, M., Albright, J., Gertz, E.R., Manuel-de-Villena, F., Bennett, B.J. 2022. Altered macronutrient composition and genetics influence the complex transcriptional network associated with adiposity in the Collaborative Cross. Genes and Nutrition. 17. Article 13. https://doi.org/10.1186/s12263-022-00714-x.

Chronic kidney disease is associated with attenuated plasma metabolome response to oral glucose tolerance testing - (Peer Reviewed Journal)
Ahmadi, A., Huda, M., Bennett, B.J., Gamboa, J., Zelnick, L., Smith, L.R., Chondronikola, M., Raftery, D., de Boer, I.H., Roshanrvan, B. 2022. Chronic kidney disease is associated with attenuated plasma metabolome response to oral glucose tolerance testing. Journal of Renal Nutrition. 33(2):316-325. https://doi.org/10.1053/j.jrn.2022.09.013.

Maternal mental health in late pregnancy and longitudinal changes in postpartum serum vitamin B-12, homocysteine, and milk B-12 concentration among Brazilian women - (Peer Reviewed Journal)
Batalha, M.A., dos Reis Costa, P.N., Ferreira, A.L., Freitas-Costa, N.C., Figueiredo, A.C., Shahab-Ferdows, S., Hampel, D., Allen, L.H., Perez-Escamilla, R., Kac, G. 2022. Maternal mental health in late pregnancy and longitudinal changes in postpartum serum vitamin B-12, homocysteine, and milk B-12 concentration among Brazilian women. Frontiers in Nutrition. 9. Article 923569. https://doi.org/10.3389/fnut.2022.923569.

Lipoxins reduce obesity-induced adipose tissue inflammation in 3D-cultured human adipocytes and explant cultures - (Peer Reviewed Journal)
Sotak, M., Rajan, M., Clark, M., Harms, M., Rani, A., Kraft, J.D., Tandio, D., Shen, T., Borkowski, K., Fiehn, O., Newman, J.W., Quiding-Jarbrink, M., Biorserud, C., Apelgren, P., Staalesen, T., Hagberg, C., Boucher, J., Wallenius, V., Lange, S., Borgeson, E. 2022. Lipoxins reduce obesity-induced adipose tissue inflammation in 3D-cultured human adipocytes and explant cultures. iScience. 25(7). Article 104602. https://doi.org/10.1016/j.isci.2022.104602.

Comprehensive analysis of B-vitamins in human milk - (Abstract Only)
Hampel, D., Shahab-Ferdows, S., Schulze, K., Allen, L.H. 2022. Comprehensive analysis of B-vitamins in human milk. Current Developments in Nutrition. 6(1). https://doi.org/10.1093/cdn/nzac063.008.

Multiassay nutritional metabolomics profiling of low vitamin A status versus adequacy is characterized by reduced plasma lipid mediators among lactating women in the Philippines: A pilot study - (Peer Reviewed Journal)
Johnson, C.M., Rosario, R., Brito, A., Agrawal, K., Fanter, R., Lietz, G., Haskell, M., Engle-Stone, R., Newman, J.W., La Frano, M.R. 2022. Multiassay nutritional metabolomics profiling of low vitamin A status versus adequacy is characterized by reduced plasma lipid mediators among lactating women in the Philippines: A pilot study. Nutrition Research. 104:118-127. https://doi.org/10.1016/j.nutres.2022.05.007.

Chicken liver and eggshell crackers as a safe and affordable animal source food for overcoming micronutrient deficits during pregnancy and lactation in Indonesia: A double-blind, randomised placebo-controlled trial - (Peer Reviewed Journal)
Diana, A., Rahmannia, S., Suhadi, Y.Z., Luftimas, D.E., Rizqi, H., Purnamasari, A.D., Jihadillah, A., Ansari, M.B., Haq, D.A., Pratiwi, A.N., Scott, S., Hampel, D., Allen, L.H., Haszard, J.J., Houghton, L.A., Gibson, R.S., Fahmida, U. 2022. Chicken liver and eggshell crackers as a safe and affordable animal source food for overcoming micronutrient deficits during pregnancy and lactation in Indonesia: A double-blind, randomised placebo-controlled trial (SISTIK growth study). Wellcome Open Research. 7. Article 167. https://doi.org/10.12688/wellcomeopenres.17879.1.

Estimating national and subnational nutrient intake distributions of global diets - (Peer Reviewed Journal)
Passarelli, S., Free, C.M., Allen, L.H., Batis, C., Beal, T., Biltoft-Jensen, A., Bromage, S., Cao, L., Castellanos-Guttierr, A., Christensen, T., Crispim, S.P., Dekkers, A., De Ridder, K., Kronsteiner-Gicevic, S., Lee, C., Li, Y., Moursi, M., Moyersoen, I., Schmidhuber, J., Shepon, A., Viana, D.F., Golden, C.D. 2022. Estimating national and subnational nutrient intake distributions of global diets. American Journal of Clinical Nutrition. Article nqac108. https://doi.org/10.1093/ajcn/nqac108.

Waking salivary cortisol associated with magnitude of cholesterol reduction in women fed a healthy whole-food diet for 8 weeks - (Peer Reviewed Journal)
Soltani, H., Keim, N.L., Laugero, K.D. 2022. Waking salivary cortisol associated with magnitude of cholesterol reduction in women fed a healthy whole-food diet for 8 weeks. Current Developments in Nutrition. 6(5). Article nzac083. https://doi.org/10.1093/cdn/nzac083.

The dose-response effects of consuming high fructose corn syrup-sweetened beverages on hepatic lipid content and insulin sensitivity in young adults - (Peer Reviewed Journal)
Sigala, D.M., Hieronimus, B., Medici, V., Lee, V., Nunez, M.V., Bremer, A.A., Cox, C.L., Price, C.A., Benyam, Y., Abdelhafez, Y., Mcgahan, J.P., Keim, N.L., Goran, M., Parcini, G., Tura, A., Sirlin, C.B., Chaudhari, A.J., Havel, P.J., Stanhope, K.L. 2022. The dose-response effects of consuming high fructose corn syrup-sweetened beverages on hepatic lipid content and insulin sensitivity in young adults. Nutrients. 14(8). Article 1648. https://doi.org/10.3390/nu14081648.

Daily supplementation of a multiple micronutrient powder improves folate but not thiamine, riboflavin, or vitamin B12 status among young Laotian children: A randomized controlled trial - (Peer Reviewed Journal)
Hinnouho, G., Hampel, D., Shahab-Ferdows, S., Barffour, M.A., McAnena, L., Arnold, C.D., Wessells, K., Kounnavong, S., Allen, L.H., Hess, S.Y. 2022. Daily supplementation of a multiple micronutrient powder improves folate but not thiamine, riboflavin, or vitamin B12 status among young Laotian children: A randomized controlled trial. European Journal of Nutrition. https://doi.org/10.1007/s00394-022-02890-3.

Assessing insulin sensitivity and postprandial triglyceridemic response phenotypes with a mixed macronutrient tolerance test - (Peer Reviewed Journal)
Newman, J.W., Krishnan, S., Borkowski, K., Adams, S.H., Stephensen, C.B., Keim, N.L. 2022. Assessing insulin sensitivity and postprandial triglyceridemic response phenotypes with a mixed macronutrient tolerance test. Frontiers in Nutrition. 9. Article 877696. https://doi.org/10.3389/fnut.2022.877696.

Diet, fecal microbiome, and trimethylamine N-oxide in a cohort of metabolically healthy United States adults - (Peer Reviewed Journal)
James, K.L., Gertz, E.R., Cervantes, E., Bonnel, E., Stephensen, C.B., Kable, M.E., Bennett, B.J. 2022. Diet, fecal microbiome, and trimethylamine N-oxide in a cohort of metabolically healthy United States adults. Nutrients. 14(7). Article 1376. https://doi.org/10.3390/nu14071376.

Plasma oxylipin profile discriminates ethnicities in subjects with non-alcoholic steatohepatitis: An exploratory analysis - (Peer Reviewed Journal)
Mazi, T.A., Borkowski, K., Fiehn, O., Bowlus, C.L., Sarkar, S., Matsukuma, K., Ali, M.R., Kieffer, D.A., Wan, Y.Y., Stanhope, K.L., Havel, P.J., Newman, J.W., Medici, V. 2022. Plasma oxylipin profile discriminates ethnicities in subjects with non-alcoholic steatohepatitis: An exploratory analysis. Metabolites. 12(2). Article 192. https://doi.org/10.3390/metabo12020192.

Satiety associated with calorie restriction and time-restricted feeding: Peripheral hormones - (Review Article)
Tacad, D.K., Tovar, A.P., Richardson, C.E., Horn, W.F., Krishnan, G.P., Keim, N.L., Krishnan, S. 2022. Satiety associated with calorie restriction and time-restricted feeding: Peripheral hormones. Advances in Nutrition. 13(3):792-820. https://doi.org/10.1093/advances/nmac014.

Pathways of parental influence on adolescent diet and obesity: A physiological stress-focused perspective - (Review Article)
Dimitratos, S.M., Swartz, J.R., Laugero, K.D. 2022. Pathways of parental influence on adolescent diet and obesity: A physiological stress-focused perspective. Nutrition Reviews. 80(70):1800-1810. Article nuac004. https://doi.org/10.1093/nutrit/nuac004.

Satiety associated with calorie restriction and time-restricted feeding: Central neuroendocrine integration - (Review Article)
Tacad, D.K., Tovar, A.P., Richardson, C.E., Horn, W.F., Keim, N.L., Krishnan, G.P., Krishnan, S. 2022. Satiety associated with calorie restriction and time-restricted feeding: Central neuroendocrine integration. Advances in Nutrition. 13(3):758-791. https://doi.org/10.1093/advances/nmac011.

The omega-3 index response to an 8 week randomized intervention containing three fatty fish meals per week is influenced by adiposity in overweight to obese women - (Peer Reviewed Journal)
Richardson, C.E., Krishnan, S., Gray, I.J., Keim, N.L., Newman, J.W. 2022. The omega-3 index response to an 8 week randomized intervention containing three fatty fish meals per week is influenced by adiposity in overweight to obese women. Frontiers in Nutrition. 9. Article 810003. https://doi.org/10.3389/fnut.2022.810003.

Almond consumption for 8 weeks altered host and microbial metabolism in comparison to a control snack in young adults - (Peer Reviewed Journal)
Dhillon, J., Newman, J.W., Fiehn, O., Ortiz, R.M. 2022. Almond consumption for 8 weeks altered host and microbial metabolism in comparison to a control snack in young adults. Journal of the American Nutrition Association. Article 2025168. https://doi.org/10.1080/07315724.2021.2025168.

Plasma choline concentration was not increased after a 6-month egg intervention in 6–9-Month-old Malawian children: results from a randomized controlled trial - (Peer Reviewed Journal)
Bragg, M.G., Prado, E.L., Arnold, C.D., Zyba, S.J., Maleta, K.M., Caswell, B.L., Bennett, B.J., Iannotti, L.L., Lutter, C.K., Stewart, C.P. 2022. Plasma choline concentration was not increased after a 6-month egg intervention among 6-9-month old Malawian children: Results from a randomized controlled trial. Current Developments in Nutrition. 6(2). Article nzab150. https://doi.org/10.1093/cdn/nzab150.

Peripherally administered amylin inhibits stress-like behaviors and enhances cognitive performance - (Peer Reviewed Journal)
Laugero, K.D., Tryon, M., Mack, C., Caldarone, B., Hanania, T., McGonigle, P., Roland, B., Parkes, D. 2021. Peripherally administered amylin inhibits stress-like behaviors and enhances cognitive performance. Physiology and Behavior. 244. Article 113668. https://doi.org/10.1016/j.physbeh.2021.113668.

B-vitamins and choline in human milk are not impacted by a preconception lipid-based nutrient supplement, but differ among three low-to-middle income settings – Findings from the women first trial - (Peer Reviewed Journal)
Young, B.E., Wescott, J., Kemp, J., Allen, L.H., Hampel, D., Garces, A.L., Figueroa, L., Goudar, S.S., Dhaded, S.M., Somannavar, M., Saleem, S., Ali, S.A., Hambridge, M., Krebs, N.F.,The Women First Working Group. 2021. B-vitamins and choline in human milk are not impacted by a preconception lipid-based nutrient supplement, but differ among three low-to-middle income settings – Findings from the women first trial. Frontiers in Nutrition. 8. Article 750680. https://doi.org/10.3389/fnut.2021.750680.

Adopting a Mediterranean-style eating pattern with low, but not moderate, unprocessed, lean red meat intake reduces fasting serum trimethylamine N-oxide (TMAO) in adults who are overweight or obese - (Peer Reviewed Journal)
Krishnan, S., O'Connor, L., Wang, Y., Gertz, E.R., Campbell, W.W., Bennett, B.J. 2021. Adopting a Mediterranean-style eating pattern with low, but not moderate, unprocessed, lean red meat intake reduces fasting serum trimethylamine N-oxide (TMAO) in adults who are overweight or obese. British Journal of Nutrition. https://doi.org/10.1017/S0007114521004694.

Resistant starch wheat increases PYY and decreases GIP but has no effect on self-reported perceptions of satiety - (Peer Reviewed Journal)
Hughes, R., Horn, W.F., Wen, A., Rust, B., Woodhouse, L.R., Newman, J.W., Keim, N.L. 2021. Resistant starch wheat increases PYY and decreases GIP but has no effect on self-reported perceptions of satiety. Appetite. 168. Article 105802. https://doi.org/10.1016/j.appet.2021.105802.

Improving LC-MS analysis of human milk B-vitamins by lactose removal - (Peer Reviewed Journal)
Hampel, D., Shahab-Ferdows, S., Newman, J.W., Allen, L.H. 2021. Improving LC-MS analysis of human milk B-vitamins by lactose removal. Journal of Chromatography B. 1183. Article 122968. https://doi.org/10.1016/j.jchromb.2021.122968.

Effects of a diet based on the Dietary Guidelines on vascular health and TMAO in women with cardiometabolic risk factors - (Peer Reviewed Journal)
Krishnan, S., Gertz, E.R., Adams, S.H., Newman, J.W., Pedersen, T.L., Keim, N.L., Bennett, B.J. 2021. Effects of a diet based on the Dietary Guidelines on vascular health and TMAO in women with cardiometabolic risk factors. Nutrition Metabolism and Cardiovascular Disease. 32(1):210-219. https://doi.org/10.1016/j.numecd.2021.09.013.

The mothers, infants, and lactation quality (MILQ) study: A multi-center collaboration - (Peer Reviewed Journal)
Allen, L.H., Hampel, D., Shahab-Ferdows, S., Andersson, M., Barros, E., Doel, A., Eriksen, K.G., Christensen, S., Islam, M., Kac, G., Keya, F.K., Michaelsen, K., Mucci, D., Njie, F., Peerson, J., Moore, S.E. 2021. The mothers, infants, and lactation quality (MILQ) study: A multi-center collaboration. Current Developments in Nutrition. 5(10). Article nzab116. https://doi.org/10.1093/cdn/nzab116.

Serum metabolomic biomarkers of perceptual speed in cognitively normal and mildly impaired subjects with fasting state stratification - (Peer Reviewed Journal)
Borkowski, K., Taha, A.Y., Pedersen, T.L., De Jager, P.L., Bennett, D.A., Arnold, M., Kaddurah-Daouk, R., Newman, J.W. 2021. Serum metabolomic biomarkers of perceptual speed in cognitively normal and mildly impaired subjects with fasting state stratification. Scientific Reports. 11. Article 18964. https://doi.org/10.1038/s41598-021-98640-2.

Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer’s disease - (Peer Reviewed Journal)
Borkowski, K., Pedersen, T.L., Seyfried, N.T., Lah, J.J., Levey, A.I., Hales, C.M., Dammer, E.B., Blach, C., Louie, G., Kaddurah-Daouk, R., Newman, J.W. 2021. Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer’s disease. Alzheimer's Research & Therapy. 13. Article 149. https://doi.org/10.1186/s13195-021-00893-6.

Four weeks of 16/8 time restrictive feeding in endurance trained male runners decreases fat mass, without affecting exercise performance - (Peer Reviewed Journal)
Tovar, A.P., Richardson, C.E., Keim, N.L., Van Loan, M.D., Davis, B., Casazza, G.A. 2021. Four weeks of 16/8 time restrictive feeding in endurance trained male runners decreases fat mass, without affecting exercise performance. Nutrients. 13(9). Article 2941. https://doi.org/10.3390/nu13092941.

Genetic and environmental influences on serum oxylipins, endocannabinoids, bile acids and steroids - (Peer Reviewed Journal)
Bermingham, K.M., Brennan, L., Segurado, R., Gray, I.J., Barron, R.E., Gibney, E.R., Ryan, M.F., Gibney, M.J., Newman, J.W., O'Sullivan, A.M. 2021. Genetic and environmental influences on serum oxylipins, endocannabinoids, bile acids and steroids. Prostaglandins Leukotrienes and Essential Fatty Acids. 173. Article 102338. https://doi.org/10.1016/j.plefa.2021.102338.

Oxylipin responses to fasting and insulin infusion in a large mammalian model of fasting-induced insulin resistance, the northern elephant seal - (Peer Reviewed Journal)
Wright, D.N., Katundu, K.G., Viscarra, J.A., Crocker, D.E., Newman, J.W., La Frano, M.R., Ortiz, R.M. 2021. Oxylipin responses to fasting and insulin infusion in a large mammalian model of fasting-induced insulin resistance, the northern elephant seal. American Journal of Physiology - Regulatory Integrative & Comparative Physiology. 321(4):R537-R546. https://doi.org/10.1152/ajpregu.00016.2021.

Association between physiological stress load and diet quality patterns differs between male and female adults - (Peer Reviewed Journal)
Dimitratos, S., Hercules, M., Stephensen, C.B., Cervantes, E., Laugero, K.D. 2021. Association between physiological stress load and diet quality patterns differs between male and female adults. Physiology and Behavior. 240. Article 113538. https://doi.org/10.1016/j.physbeh.2021.113538.

Consuming sucrose- or HFCS-sweetened beverages increases hepatic lipid and decreases insulin sensitivity in adults - (Peer Reviewed Journal)
Sigala, D.M., Hieronimus, B., Medici, V., Lee, V., Nunez, M.V., Bremer, A.A., Cox, C.L., Price, C.A., Benyam, Y., Chaudhari, A.J., Abdelhafez, Y., McGahan, J.P., Goran, M., Sirlin, C.B., Pacini, G., Tura, A., Keim, N.L., Havel, P.J., Stanhope, K.L. 2021. Consuming sucrose- or HFCS-sweetened beverages increases hepatic lipid and decreases insulin sensitivity in adults. Journal of Clinical Endocrinology and Metabolism. 106(11):3248-3264. https://doi.org/10.1210/clinem/dgab508.

Host lipidome and tuberculosis treatment failure - (Peer Reviewed Journal)
Shivakoti, R., Newman, J.W., Hanna, L.E., Queiroz, A.T., Borkowski, K., Gupte, A.N., Paradkar, M., Satyamurthi, P., Kulkarni, V., Selva, M., Pradhan, N., Shivakumar, S.V., Natarajan, S., Karunaianantham, R., Gupte, N., Thiruvengadam, K., Fiehn, O., Bharadwaj, R., Kagal, A., Gaikwad, S., Sangle, S., Golub, J.E., Andrade, B.B., Mave, V., Gupta, A., Padmapriyadarsini, C. 2022. Host lipidome and tuberculosis treatment failure. European Respiratory Journal. 59. Article 2004532. https://doi.org/10.1183/13993003.04532-2020.

Target product profiles for a micronutrient assessment tool and associated blood collection device for use in population-based surveys: An expert consensus - (Peer Reviewed Journal)
Smith, E.R., Lee, J., Allen, L.H., Boyle, D.S., Brindle, E., Craft, N.E., Dalmiya, N., Erhardt, J., Garrett, D., Jefferds, M., Kavishe, F., Killilea, D.W., Kung'U, J.K., Kurpad, A., Loechl, C.U., Moore, S.E., Namaste, S.M., Pfeiffer, C.M., Rohner, F., Schulze, K., Shaheen, N., Soofi, S., Winichagoon, P., Thomas, B., Osendarp, S., Rawat, R. 2021. Target product profiles for a micronutrient assessment tool and associated blood collection device for use in population-based surveys: An expert consensus. MedrXiv. https://doi.org/10.1101/2021.05.13.21257124.

Factors associated with longitudinal changes in B-vitamin and choline concentrations of human milk - (Peer Reviewed Journal)
Batalha, M.A., Ferreira, A.L., Freitas-Costa, N.C., Figueiredo, A.C., Carrilho, T.R., Shahab-Ferdows, S., Hampel, D., Allen, L.H., Perez-Escamilla, R., Kac, G. 2021. Factors associated with longitudinal changes in B-vitamin and choline concentrations of human milk. American Journal of Clinical Nutrition. 114(4):1560-1573. https://doi.org/10.1093/ajcn/nqab191.

Thiamine supplementation holds neurocognitive benefits for breastfed infants during the first year of life - (Peer Reviewed Journal)
Measelle, J.R., Baldwin, D.A., Gallant, J., Chan, K., Green, T.J., Wieringa, F.T., Borath, M., Sophonneary, P., Hampel, D., Shahab-Ferdows, S., Allen, L.H., Kroeun, H., Whitfield, K.C. 2021. Thiamine supplementation holds neurocognitive benefits for breastfed infants during the first year of life. Annals of the New York Academy of Sciences. https://doi.org/10.1111/nyas.14610.

Healthy eating index patterns in adults by sex and age predict cardiometabolic risk factors in a cross-sectional study - (Peer Reviewed Journal)
Artegoitia Etchev, V.M., Krishnan, S., Bonnel, E.L., Stephensen, C.B., Keim, N.L., Newman, J.W. 2021. Healthy eating index patterns in adults by sex and age predict cardiometabolic risk factors in a cross-sectional study. Biomed Central (BMC) Nutrition. 7. Article 30. https://doi.org/10.1186/s40795-021-00432-4.

Human milk metabolic profiling using Biocrates MxP® Quant 500 kit - (Abstract Only)
Hampel, D., Shahab-Ferdows, S., Kac, G., Allen, L.H. 2021. Human milk metabolic profiling using Biocrates MxP® Quant 500 kit. Current Developments in Nutrition. 5(2). https://doi.org/10.1093/cdn/nzab048_009.

Hepatic transcriptional profile reveals the role of diet and genetic backgrounds on metabolic traits in female progenitor strains of the Collaborative Cross - (Peer Reviewed Journal)
Kim, M., Huda, N., O'Connor, A., Albright, J., Durbin-Johnson, B., Bennett, B.J. 2021. Hepatic transcriptional profile reveals the role of diet and genetic backgrounds on metabolic traits in female progenitor strains of the Collaborative Cross. Physiological Genomics. 53(5):173-192. https://doi.org/10.1152/physiolgenomics.00140.2020.

Diet affects glycosylation of serum proteins in women at risk for cardiometabolic disease - (Peer Reviewed Journal)
Kim, T., Xie, Y., Li, Q., Artegoitia Etchev, V.M., Lebrilla, C., Keim, N.L., Adams, S., Krishnan, S. 2021. Diet affects glycosylation of serum proteins in women at risk for cardiometabolic disease. European Journal of Nutrition. 60:3727-3741. https://doi.org/10.1007/s00394-021-02539-7.

Ethnicity-specific alterations of plasma and hepatic lipidomic profiles are related to high NAFLD rate and severity in Hispanic Americans, a pilot study - (Peer Reviewed Journal)
Mazi, T.A., Borkowski, K., Newman, J.W., Fiehn, O., Bowlus, C., Srkar, S., Matsukuma, K., Ali, M.R., Kieffer, D.A., Wan, Y.Y., Stanhope, K.L., Havel, P.J., Medici, V. 2021. Ethnicity-specific alterations of plasma and hepatic lipidomic profiles are related to high NAFLD rate and severity in Hispanic Americans, a pilot study. Free Radical Biology and Medicine. https://doi.org/10.1101/2021.04.08.21254907.

Maternal postpartum deworming and infant milk intake: Secondary outcomes from a trial - (Peer Reviewed Journal)
Mofid, L.S., Casapia, M., Montresor, A., Rahme, E., Marquis, G.S., Vercruysse, J., Allen, L.H., Blouin, B., Razuri, H., Pezo, L., Gyorkos, T.W. 2021. Maternal postpartum deworming and infant milk intake: Secondary outcomes from a trial. Maternal and Child Nutrition. Article e13183. https://doi.org/10.1111/mcn.13183.

Low-dose thiamine supplementation of lactating Cambodian mothers improves human milk thiamine concentrations: a randomized controlled trial - (Peer Reviewed Journal)
Gallant, J., Chan, K., Green, T.J., Wieringa, F.T., Leemaqz, S., Ngik, R., Measelle, J.R., Baldwin, D., Mam, B., Sophonneary, P., Yelland, L.N., Hampel, D., Shahab-Ferdows, S., Allen, L.H., Jones, K.S., Koulman, A., Parkington, D., Meadows, S.R., Kroeun, H., Whitfield, K.C. 2021. Low-dose thiamine supplementation of lactating Cambodian mothers improves human milk thiamine concentrations: a randomized controlled trial. American Journal of Clinical Nutrition. 114(1):90-100. https://doi.org/10.1093/ajcn/nqab052.

Modulating the microbiota as a therapeutic intervention for Type 2 Diabetes - (Review Article)
Huda, N., Kim, M., Bennett, B.J. 2021. Modulating the microbiota as a therapeutic intervention for Type 2 Diabetes. Frontiers in Endocrinology. 12. Article 632335. https://doi.org/10.3389/fendo.2021.632335.

Gestational long-term hypoxia induces metabolomic reprogramming and phenotypic transformations in fetal sheep pulmonary arteries - (Peer Reviewed Journal)
Leslie, E., Lopez, V., Anti, N., Alvarez, R., Kafeero, I., Welsh, D.G., Romero, M., Kaushal, S., Johnson, C.M., Bosviel, R., Blazenovic, I., Song, R., Brito, A., La Frano, M.R., Zhang, L., Newman, J.W., Fiehn, O., Wilson, S. 2021. Gestational long-term hypoxia induces metabolomic reprogramming and phenotypic transformations in fetal sheep pulmonary arteries. American Journal of Physiology - Lung Cellular and Molecular Physiology. 320(5):L770-L784. https://doi.org/10.1152/ajplung.00469.2020.

Sequence meets function—Microbiota and cardiovascular disease - (Review Article)
Kim, M., Huda, N., Bennett, B.J. 2021. Sequence meets function—Microbiota and cardiovascular disease. Cardiovascular Research. https://doi.org/10.1093/cvr/cvab030.

Exogenous GLP-1 stimulates TCA cycle and suppresses gluconeogenesis and ketogenesis in late-fasted northern elephant seals pups - (Peer Reviewed Journal)
Dhillon, J., Viscarra, J.A., Newman, J.W., Fiehn, O., Crocker, D.E., Ortiz, R.M. 2021. Exogenous GLP-1 stimulates TCA cycle and suppresses gluconeogenesis and ketogenesis in late-fasted northern elephant seals pups. American Journal of Physiology - Regulatory Integrative & Comparative Physiology. 320(4):R393-R401. https://doi.org/10.1152/ajpregu.00211.2020.

N-3 PUFA improved post-menopausal depression induced by maternal separation and chronic mild stress through serotonergic pathway in rats – effect associated with lipid mediators - (Peer Reviewed Journal)
Choi, J., Borkowski, K., Newman, J.W., Park, Y. 2021. N-3 PUFA improved post-menopausal depression induced by maternal separation and chronic mild stress through serotonergic pathway in rats – effect associated with lipid mediators. Journal of Nutritional Biochemistry. 91. Article 108599. https://doi.org/10.1016/j.jnutbio.2021.108599.

Effects of consuming sugar-sweetened beverages for 2 weeks on 24-h circulating leptin profiles, ad libitum food intake and body weight in young adults - (Peer Reviewed Journal)
Sigala, D.M., Widaman, A., Herionimus, B., Nunez, M., Lee, V., Benyam, Y., Bremer, A.A., Medici, V., Havel, P., Stanhope, K.L., Keim, N.L. 2020. Effects of consuming sugar-sweetened beverages for 2 weeks on 24-h circulating leptin profiles, ad libitum food intake and body weight in young adults. Nutrients. 12(2). Article 3893. https://doi.org/10.3390/nu12123893.

Genetic background shapes phenotypic response to diet for adiposity in the Collaborative Cross - (Peer Reviewed Journal)
Yam, P., Albright, J., Verhague, M., Gertz, E.R., Pardo-Manuel De Vill, V., Bennett, B.J. 2021. Genetic background shapes phenotypic response to diet for adiposity in the Collaborative Cross. Frontiers in Genetics. 11. Article 615012. https://doi.org/10.3389/fgene.2020.615012.

Small-quantity lipid-based nutrient supplements do not affect plasma or milk retinol concentrations among Malawian mothers, or plasma retinol concentrations among young Malawian or Ghanaian children in two randomized trials - (Peer Reviewed Journal)
Haskell, M.J., Young, R., Lartey, A., Eyram Teiko Okronipa, H., Maleta, K., Ashorn, U., Jorgensen, J.M., Yue-Mei, F., Arnold, C., Allen, L.H., Per, A., Dewey, K.G. 2021. Small-quantity lipid-based nutrient supplements do not affect plasma or milk retinol concentrations among Malawian mothers, or plasma retinol concentrations among young Malawian or Ghanaian children in two randomized trials. Journal of Nutrition. 151(4):1029-1037. https://doi.org/10.1093/jn/nxaa439.

High-throughput analysis of water-soluble forms of choline and related metabolites in human milk by UPLC-MS/MS and its application - (Peer Reviewed Journal)
Hampel, D., Shahab-Ferdows, S., Nguyen, N., Gilberto, K., Allen, L.H. 2021. High-throughput analysis of water-soluble forms of choline and related metabolites in human milk by UPLC-MS/MS and its application. Frontiers in Nutrition. 7. Article 604570. https://doi.org/10.3389/fnut.2020.604570.

Plasma and serum oxylipin, endocannabinoid, bile acid, steroid, fatty acid and nonsteroidal anti-inflammatory drug quantification in a 96-well plate format - (Peer Reviewed Journal)
Pedersen, T.L., Gray, I.J., Newman, J.W. 2020. Plasma and serum oxylipin, endocannabinoid, bile acid, steroid, fatty acid and nonsteroidal anti-inflammatory drug quantification in a 96-well plate format. Analytica Chimica Acta. 1143:189-200. https://doi.org/10.1016/j.aca.2020.11.019.

Maternal plasma folate concentration is positively associated with serum total cholesterol and low-density lipoprotein across the three trimesters of pregnancy - (Peer Reviewed Journal)
Da Silva, M.T., Mujica-Coopman, M.F., Figueiredo, A.C., Hampel, D., Vieira, L.S., Farias, D.R., Shahab-Ferdows, S., Allen, L.H., Brito, A., Lamers, Y., Kac, G., Vaz, J.S. 2020. Maternal plasma folate concentration is positively associated with serum total cholesterol and low-density lipoprotein across the three trimesters of pregnancy. Scientific Reports. 10. Article 20141. https://doi.org/10.1038/s41598-020-77231-7.

Weight loss, but not dairy composition of diet, moderately affects satiety and postprandial gut hormone patterns in adults - (Peer Reviewed Journal)
Krishnan, S., Adams, S., Witbracht, M.G., Woodhouse, L.R., Piccolo, B.D., Thomas, A.P., Souza, E.C., Horn, W.F., Gertz, E.R., Van Loan, M.D., Keim, N.L. 2020. Weight loss, but not dairy composition of diet, moderately affects satiety and postprandial gut hormone patterns in adults. Journal of Nutrition. 151(1):245-254. https://doi.org/10.1093/jn/nxaa327.

Synergistic effects of fructose and glucose on lipoprotein risk factors for cardiovascular disease in young adults - (Peer Reviewed Journal)
Hieronimus, B., Medici, V., Bremer, A.A., Lee, V., Nunez, M.V., Sigala, D.M., Keim, N.L., Havel, P.J., Stanhope, K.L. 2020. Synergistic effects of fructose and glucose on lipoprotein risk factors for cardiovascular disease in young adults. Metabolism. 112. Article 154356. https://doi.org/10.1016/j.metabol.2020.154356.

Mid-gestation serum lipidomic profile associations with spontaneous preterm birth are influenced by body mass index - (Peer Reviewed Journal)
Borkowski, K., Newman, J.W., Aghaeepour, N., Mayo, J.A., Blazenovic, I., Fiehn, O., Stevenson, D.K., Shaw, G.M., Carmichael, S.L. 2020. Mid-gestation serum lipidomic profile associations with spontaneous preterm birth are influenced by body mass index. PLoS ONE. 15(11). Article e0239115. https://doi.org/10.1371/journal.pone.0239115.

Harmonized procedures lead to comparable quantification of total oxylipins across laboratories - (Peer Reviewed Journal)
Mainka, M., Dalle, C., Petera, M., Dalloux-Chioccioli, J., Kampschulte, N., Ostermann, A.I., Rothe, M., Bertrand-Michel, J., Newman, J.W., Gladine, C., Schebb, N.H. 2020. Harmonized procedures lead to comparable quantification of total oxylipins across laboratories. Journal of Lipid Research. 61(11):1424-1436. https://doi.org/10.1194/jlr.RA120000991.

Linoleic acid-rich oil supplementation increases total and high-molecular-weight adiponectin and alters plasma oxylipins in postmenopausal women with metabolic syndrome - (Peer Reviewed Journal)
Cole, R.M., Puchala, S., Ke, J., Abdel-Rasoul, M., Harlow, K., O'Donnell, B., Bradley, D., Andridge, R., Borkowski, K., Newman, J.W., Belury, M.A. 2020. Linoleic acid-rich oil supplementation increases total and high-molecular-weight adiponectin and alters plasma oxylipins in postmenopausal women with metabolic syndrome. Current Developments in Nutrition. 4(9). Article nzaa136. https://doi.org/10.1093/cdn/nzaa136.

Effects of dietary glucose and fructose on copper, iron, and zinc metabolism parameters in humans - (Peer Reviewed Journal)
Harder, N.H., Hieronimus, B., Stanhope, K.L., Shibata, N.M., Lee, V., Nunez, M.V., Keim, N.L., Bremer, A., Havel, P.J., Heffern, M.C., Medici, V. 2020. Effects of dietary glucose and fructose on copper, iron, and zinc metabolism parameters in humans. Nutrients. 12(9):2581. https://doi.org/10.3390/nu12092581.

Risk factors for anaemia among Ghanaian women and children vary by population group and climate zone - (Peer Reviewed Journal)
Petry, N., Wirth, J.P., Adu-Afarwuah, S., Wegmuller, R., Woodruff, B.A., Tanumihardjo, S.A., Bentil, H., Donkor, W.E., Williams, T.N., Shahab-Ferdows, S., Selenje, L., Mahama, A., Steiner-Asiedu, M., Rohner, F. 2020. Risk factors for anaemia among Ghanaian women and children vary by population group and climate zone. Maternal and Child Nutrition. 17(2). Article e13076. https://doi.org/10.1111/mcn.13076.

Genetic architecture modulates diet-induced hepatic mRNA and miRNA expression profiles in Diversity Outbred mice - (Peer Reviewed Journal)
Que, E.S., James, K.L., Coffey, A., Smallwood, T.L., Albright, J., Pomp, D., Sethupathy, P., Bennett, B.J. 2020. Genetic architecture modulates diet-induced hepatic mRNA and miRNA expression profiles in Diversity Outbred mice. Genetics. 216(1):241-259. https://doi.org/10.1534/genetics.120.303481.

Determining the genetic regulation of trimethylamine N-oxide in female diversity outbred mice - (Abstract Only)

High-fat diet–induced colonocyte dysfunction escalates microbiota-derived trimethylamine N-oxide - (Peer Reviewed Journal)
Yoo, W., Zieba, J.K., Foegeding, N.J., Torres, T.P., Shelton, C.D., Shealy, N.G., Byndloss, A.J., Cevallos, S.A., Gertz, E.R., Tiffany, C.R., Thomas, J., Litvak, Y., Nguyen, H., Olsan, E.E., Bennett, B.J., Rathmell, J.C., Major, A.S., Baumler, A.J., Byndloss, M.X. 2021. High-fat diet–induced colonocyte dysfunction escalates microbiota-derived trimethylamine N-oxide. Science. 373(6556):813-818. https://doi.org/10.1126/science.aba3683.

Metabolomics reveals altered hepatic bile acids, gut microbiome metabolites, and cell membrane lipids associated with marginal vitamin A deficiency in a Mongolian gerbil model - (Peer Reviewed Journal)
La Frano, M.R., Brito, A., Johnson, C.M., Wilhelmson, B., Gannon, B., Fanter, R.K., Pedersen, T.L., Tanumihardjo, S.A., Newman, J.W. 2020. Metabolomics reveals altered hepatic bile acids, gut microbiome metabolites, and cell membrane lipids associated with marginal vitamin A deficiency in a Mongolian gerbil model. Molecular Nutrition and Food Research. 64(13). https://doi.org/10.1002/mnfr.201901319.

Understanding the intersection of climate/environmental change, health, agriculture and improved nutrition: a case study on micronutrient nutrition and animal source foods - (Peer Reviewed Journal)
Raiten, D.J., Allen, L.H., Slavin, J.L., Mitloehner, F.M., Thoma, G.J., Haggerty, P.A., Finley, J.W. 2020. Understanding the intersection of climate/environmental change, health, agriculture and improved nutrition: a case study on micronutrient nutrition and animal source foods. Current Developments in Nutrition. 4(7). https://doi.org/10.1093/cdn/nzaa087.

Effects of inflammation and soluble epoxide hydrolase inhibition on oxylipin composition of very low-density lipoproteins in isolated perfused rat livers - (Peer Reviewed Journal)
Walker, R.E., Savinova, O.V., Pedersen, T.L., Newman, J.W., Shearer, G.C. 2021. Effects of inflammation and soluble epoxide hydrolase inhibition on oxylipin composition of very low-density lipoproteins in isolated perfused rat livers. Physiological Reports. 9(4). Article e14480. https://doi.org/10.14814/phy2.14480.

Trimethylamine-N-oxide (TMAO) is not associated with average daily inatke of red meat or TMAO precursor foods in a generally healthy population - (Abstract Only)
Kristen, J., Gertz, E.R., Stephensen, C.B., Bennett, B.J. 2020. Trimethylamine-N-oxide (TMAO) is not associated with average daily inatke of red meat or TMAO precursor foods in a generally healthy population. Current Developments in Nutrition. 4(2):37. https://doi.org/10.1093/cdn/nzaa040_037.

Sexual dimorphism of atherosclerosis by gut microbiome in a hyperlipidemic diversity outbred F1 mouse population - (Abstract Only)
Kim, M., Huda, N., Que, E.S., Gertz, E.R., Bennett, B.J. 2020. Sexual dimorphism of atherosclerosis by gut microbiome in a hyperlipidemic diversity outbred F1 mouse population. Current Developments in Nutrition. 4(2):1569. https://doi.org/10.1093/cdn/nzaa062_026.

Genetic background heavily impacts effects of diet on obesity in a collaborative cross population - (Abstract Only)
Verhague, M., Albright, J., Yam, P., Bennett, B.J. 2020. Genetic background heavily impacts effects of diet on obesity in a collaborative cross population. Current Developments in Nutrition. (4)2:1282. https://doi.org/10.1093/cdn/nzaa058_040.

Vitamin B12 is low in milk of early postpartum women in urban Tanzania, and was not significantly increased by high dose supplementation - (Peer Reviewed Journal)
Lweno, O.N., Sudfeld, C.R., Hertzmark, E., Manji, K.P., Aboud, S., Noor, R.A., Masanja, H., Salim, N., Shahab-Ferdows, S., Allen, L.H., Fawzi, W. 2020. Vitamin B12 is low in milk of early postpartum women in urban Tanzania, and was not significantly increased by high dose supplementation. Nutrients. 12(4). https://doi.org/10.3390/nu12040963.

Why the derivation of nutrient reference values should be harmonized and how it can be accomplished - (Peer Reviewed Journal)
Yaktine, A.L., King, J.C., Allen, L.H. 2020. Why the derivation of nutrient reference values should be harmonized and how it can be accomplished. Advances in Nutrition. https://doi.org/10.1093/advances/nmaa048.

Microbial modulation of host body composition and plasma metabolic profile - (Peer Reviewed Journal)
Huda, N.M., Winnike, J., Crowell, J., O'Connor, A., Bennett, B.J. 2020. Microbial modulation of host body composition and plasma metabolic profile. Scientific Reports. 10. https://doi.org/10.1038/s41598-020-63214-1.

Gestational high-altitude hypoxia and metabolomic reprogramming in pulmonary arteries from fetal sheep - (Abstract Only)
Leslie, E., Jones, B., Alvarez, R., Dasgupta, C., Fiehn, O., Bosviel, R., Newman, J.W., La Frano, M., Zhang, L., Wilson, S.M. 2020. Gestational high-altitude hypoxia and metabolomic reprogramming in pulmonary arteries from fetal sheep. Journal of Federation of American Societies for Experimental Biology. 34(S1). https://doi.org/10.1096/fasebj.2020.34.s1.03778.

Metabolome and microbiome alterations related to short-term feeding of a micronutrient-fortified, high-quality legume protein-based food product to stunted school age children: A randomized controlled pilot trial - (Peer Reviewed Journal)
Varkey, A., Devi, S., Mukhopadhyay, A., Kamat, N.G., Pauline, M., Dharmar, M., Holt, R., Allen, L.H., Thomas, T., Keen, C.I., Kurpad, A. 2020. Metabolome and microbiome alterations related to short-term feeding of a micronutrient-fortified, high-quality legume protein-based food product to stunted school age children: A randomized controlled pilot trial. Clinical Nutrition. https://doi.org/10.1016/j.clnu.2020.02.018.

Liking and acceptability of whole grains increases with a six-week exposure but preferences for foods varying in taste and fat content are not altered: a randomized controlled trial - (Peer Reviewed Journal)
De Leon, A., Burnett, D.J., Rust, B.M., Casperson, S.L., Horn, W.F., Keim, N.L. 2020. Liking and acceptability of whole grains increases with a six-week exposure but preferences for foods varying in taste and fat content are not altered: a randomized controlled trial. Current Developments in Nutrition. 4(3). https://doi.org/10.1093/cdn/nzaa023.

Challenges in designing and delivering diets and assessing adherence: A randomized controlled trial evaluating the 2010 Dietary Guidelines for Americans - (Peer Reviewed Journal)
Krishnan, S., Lee, F., Burnett, D.J., Kan, A., Bonnel, E.L., Allen, L.H., Adams, S.H., Keim, N.L. 2020. Challenges in designing and delivering diets and assessing adherence: A randomized controlled trial evaluating the 2010 Dietary Guidelines for Americans. Current Developments in Nutrition. 4(3). https://doi.org/10.1093/cdn/nzaa022.

Vitamin B12 concentrations in milk from Norwegian women during the six first months of lactation - (Peer Reviewed Journal)
Henjum, S., Manger, M., Hampel, D., Brantsæter, A.L., Shahab-Ferdows, S., Bastani, N.E., Strand, T.A., Refsum, H., Allen, L.H. 2020. Vitamin B12 concentrations in milk from Norwegian women during the six first months of lactation. European Journal of Clinical Nutrition. 74:749-756. https://doi.org/10.1038/s41430-020-0567-x.

Anemia, micronutrient deficiencies, malaria, hemoglobinopathies and malnutrition in young children and non-pregnant women in Ghana: Findings from a national survey - (Peer Reviewed Journal)
Wegmuller, R., Bentil, H., Wirth, J.P., Petry, N., Tanumihadrjo, S.A., Allen, L.H., Williams, T.N., Selenje, L., Mahama, A., Amaoful, E., Steiner-Asiedu, M., Adu-Afarwuah, S., Rohner, F. 2020. Anemia, micronutrient deficiencies, malaria, hemoglobinopathies and malnutrition in young children and non-pregnant women in Ghana: Findings from a national survey. PLoS ONE. 15(1). Article e0228258. https://doi.org/10.1371/journal.pone.0228258.

Amino acid digestibility of extruded chickpea and yellow pea protein is high and comparable in moderately stunted South Indian children with use of a dual stable isotope tracer method - (Peer Reviewed Journal)
Devi, S.K., Varkey, A., Dharmar, M., Holt, R.R., Allen, L.H., Sheshshayee, M.S., Preston, T., Keen, K.L., Kurpad, A. 2020. Amino acid digestibility of extruded chickpea and yellow pea protein is high and comparable in moderately stunted South Indian children with use of a dual stable isotope tracer method. Journal of Nutrition. 150(5):1178-1185. https://doi.org/10.1093/jn/nxaa004.

Ectopic expression of the Stabilin2 gene triggered by an intracisternal A particle (IAP) element in DBA/2J strain of mice - (Peer Reviewed Journal)
Maeda-Smithies, N., Hiller, S., Dong, S., Suk Kim, H., Bennett, B.J., Kayashima, Y. 2020. Ectopic expression of the Stabilin2 gene triggered by an intracisternal A particle (IAP) element in DBA/2J strain of mice. Mammalian Genome. 31:2-16. https://doi.org/10.1007/s00335-019-09824-1.

Low serum B12 concentrations are associated with low B12 dietary intake but not with Helicobacter pylori infection or abnormal gastric function in rural Mexican women - (Peer Reviewed Journal)
Anaya-Loyola, M.A., Brito, A., Vergara-Castaneda, H., Sosa, C., Rosado, J., Allen, L.H. 2019. Low serum B12 concentrations are associated with low B12 dietary intake but not with Helicobacter pylori infection or abnormal gastric function in rural Mexican women. Nutrients. 11(12):2922. https://doi.org/10.3390/nu11122922.

Alpha-Linolenic acid-enriched butter attenuated high fat diet-induced insulin resistance and inflammation by promoting bioconversion of n-3 PUFA and subsequent oxylipin formation - (Peer Reviewed Journal)
Fan, R., Kim, J., You, M., Giraud, D., Toney, A.M., Shin, S., Kim, S., Borkowski, K., Newman, J.W., Chung, S. 2019. Alpha-Linolenic acid-enriched butter attenuated high fat diet-induced insulin resistance and inflammation by promoting bioconversion of n-3 PUFA and subsequent oxylipin formation. Journal of Nutritional Biochemistry. 76. https://doi.org/10.1016/j.jnutbio.2019.108285.

Increasing dietary carbohydrate as part of a healthy whole food diet intervention dampens eight week changes in salivary cortisol and cortisol responsiveness - (Peer Reviewed Journal)
Soltani, H., Keim, N.L., Laugero, K.D. 2019. Increasing dietary carbohydrate as part of a healthy whole food diet intervention dampens eight week changes in salivary cortisol and cortisol responsiveness. Nutrients. 11(11). https://doi.org/10.3390/nu11112563.

Total water-soluble choline concentration does not differ in milk from vegan, vegetarian, and nonvegetarian lactating women - (Peer Reviewed Journal)
Perrin, M.T., Pawlak, R., Allen, L.H., Hampel, D. 2019. Total water-soluble choline concentration does not differ in milk from vegan, vegetarian, and nonvegetarian lactating women. Journal of Nutrition. 150(3):512-517. https://doi.org/10.1093/jn/nxz257.

Total water-soluble choline concentration does not differ in milk from vegan, vegetarian, and non-vegetarian lactating women - (Peer Reviewed Journal)
Perrin, M.T., Pawlak, R., Allen, L.H., Hampel, D. 2019. Total water-soluble choline concentration does not differ in milk from vegan, vegetarian, and non-vegetarian lactating women. Journal of Nutrition. 150(3):512-517. https://doi.org/10.1093/jn/nxz257.

Diesel exhaust particles dysregulate multiple immunological pathways in murine macrophages: Lessons from microarray and scRNA-seq technologies - (Peer Reviewed Journal)
Bhetraratana, M., Orozco, L.D., Hong, J., Diamante, G., Majid, S., Bennett, B.J., Ahn, I., Yang, X., Lusis, A.J., Araujo, J.A. 2019. Diesel exhaust particles dysregulate multiple immunological pathways in murine macrophages: Lessons from microarray and scRNA-seq technologies . Archives of Biochemistry and Biophysics. https://doi.org/10.1016/j.abb.2019.108116.

Luteal lipids regulate progesterone production and may modulate immune cell function during the estrous cycle and pregnancy - (Peer Reviewed Journal)
Hughes, C.H., Bosviel, R., Newman, J.W., Pate, J.L. 2019. Luteal lipids regulate progesterone production and may modulate immune cell function during the estrous cycle and pregnancy. Frontiers in Endocrinology. 10. https://doi.org/10.3389/fendo.2019.00662.

Changes in micronutrient and inflammation serum biomarker concentrations after a norovirus human challenge - (Peer Reviewed Journal)
Williams, A.M., Ladva, C.N., Leon, J.S., Lopman, B.A., Tangpricha, V., Whitehead, R.D., Armitage, A.E., Wray, K., Morovat, A., Pasricha, S., Thurnham, D., Tanumihardjo, S.A., Shahab-Ferdows, S., Allen, L.H., Flores-Ayala, R.C., Suchdev, P.S. 2019. Changes in micronutrient and inflammation serum biomarker concentrations after a norovirus human challenge. Journal of Nutrition. 110(6):1456-1464. https://doi.org/10.1093/ajcn/nqz201.

Validation and application of Biocrates AbsoluteIDQ® p180 targeted metabolomics kit using human milk - (Peer Reviewed Journal)
Hampel, D., Shahab-Ferdows, S., Hossain, M., Islam, M., Ahmed, T., Allen, L.H. 2019. Validation and application of Biocrates AbsoluteIDQ® p180 targeted metabolomics kit using human milk. Nutrients. 11(8):1733. https://doi.org/10.3390/nu11081733.

Cohort description of the Madagascar health and environmental research-antongil (MAHERY-Antongil) study in Madagascar - (Peer Reviewed Journal)
Golden, C.D., Borgerson, C., Rice, B.L., Allen, L.H., Anjaranirina, J.G., Barrett, C.B., Boateng, G., Gephart, J.A., Hampel, D., Hartl, D.L., Knippenberg, E., Myers, S.S., Ralalason, D.H., Ramihantaniarivo, H., Randriamady, H.J., Shahab-Ferdows, S., Vaitla, B., Volkman, S.K., Vonona, M.A. 2019. Cohort description of the Madagascar health and environmental research-antongil (MAHERY-Antongil) study in Madagascar. Frontiers in Nutrition. 6:109. https://doi.org/10.3389/fnut.2019.00109.

Effects of fructose or glucose on circulating apoCIII and triglyceride and cholesterol content of lipoprotein subfractions in humans - (Peer Reviewed Journal)
Hieronimus, B., Griffen, S.C., Keim, N.L., Bremer, A.A., Berglund, L., Nakajima, K., Havel, P.J., Stanhope, K. 2019. Effects of fructose or glucose on circulating apoCIII and triglyceride and cholesterol content of lipoprotein subfractions in humans. Journal of Clinical Medicine. 8(7):913. https://doi.org/10.3390/jcm8070913.

Endocannabinoid metabolome characterization of milk from Guatemalan women living in the Western Highlands - (Peer Reviewed Journal)
Gaitan, A.V., Wood, J.T., Solomons, N.W., Donohue, J.A., Ji, L., Liu, Y., Nikas, S.P., Zhang, F., Allen, L.H., Makriyannis, A., Lammi-Keefe, C.J. 2019. Endocannabinoid metabolome characterization of milk from Guatemalan women living in the Western Highlands. Current Developments in Nutrition. 3(6):1-6. https://doi.org/10.1093/cdn/nzz018.

Micronutrient intakes of lactating mothers and their association with breast milk concentrations and micronutrient adequacy of exclusively breastfed Indonesian infants - (Peer Reviewed Journal)
Daniels, L., Gibson, R.S., Diana, A., Haszard, J.J., Rahmannia, S., Luftimas, D.E., Hambel, D., Shahab-Ferdows, S., Reid, M., Melo, L., Lamers, Y., Allen, L.H., Houghton, L.A. 2019. Micronutrient intakes of lactating mothers and their association with breast milk concentrations and micronutrient adequacy of exclusively breastfed Indonesian infants. American Journal of Clinical Nutrition. 110(2):391-400. https://doi.org/10.1093/ajcn/nqz047.

Prenatal iron deficiency and replete iron status are associated with adverse birth outcomes, but associations differ in Ghana and Malawi - (Peer Reviewed Journal)
Oaks, B.M., Jorgensen, J.M., Baldiviez, L.M., Adu-Afarwuah, S., Maleta, K., Okronipa, H., Sadalaki, J., Lartey, A., Ashorn, P., Ashorn, U., Vosti, S., Allen, L.H., Dewey, K.G. 2019. Prenatal iron deficiency and replete iron status are associated with adverse birth outcomes, but associations differ in Ghana and Malawi. Journal of Nutrition. 149(3):513-521. https://doi.org/10.1093/jn/nxy278.

Effects of lipid-based nutrient supplements and infant and young child feeding counseling with or without improved water, sanitation, and hygiene (WASH) on anemia and micronutrient status: results from two cluster randomized - (Peer Reviewed Journal)
Stewart, C.P., Dewey, K.G., Lin, A., Pickering, A.J., Byrd, K.A., Jannat, K., Ali, S., Rao, G., Dentz, H.N., Kiprotich, M., Arnold, C.D., Arnold, B.F., Allen, L.H., Shahab-Ferdows, S., Ercumen, A., Grembi, J.A., Naser, A.M., Rahman, M., Unicomb, L., Colford, J.M., Luby, S.P., Null, C. 2019. Effects of lipid-based nutrient supplements and infant and young child feeding counseling with or without improved water, sanitation, and hygiene (WASH) on anemia and micronutrient status: results from two cluster randomized trials in Kenya and Bangladesh. American Journal of Clinical Nutrition. 109(1):148-164. https://doi.org/10.1093/ajcn/nqy239.

Vitamin B12 added as a fortificant to flour retains high bioavailability when baked in bread - (Peer Reviewed Journal)
Garrod, M.G., Buchholz, B.A., Miller, J.W., Haack, K.W., Green, R., Allen, L.H. 2018. Vitamin B12 added as a fortificant to flour retains high bioavailability when baked in bread. Nuclear Instruments and Methods in Physics Research. 438:136-140. https://doi.org/10.1016/j.nimb.2018.05.042.

A randomized controlled-feeding trial based on the Dietary Guidelines for Americans on cardiometabolic health indexes - (Peer Reviewed Journal)
Krishnan, S., Adams, S.H., Allen, L.H., Laugero, K.D., Newman, J.W., Stephensen, C.B., Burnett, D.J., Witbracht, M., Welch, L.C., Que, E.S., Keim, N.L. 2018. A randomized controlled-feeding trial based on the Dietary Guidelines for Americans on cardiometabolic health indexes. American Journal of Clinical Nutrition. 108(2):266-278. https://doi.org/10.1093/ajcn/nqy113.