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ARS Home » Northeast Area » Beltsville, Maryland (BHNRC) » Beltsville Human Nutrition Research Center » Methods and Application of Food Composition Laboratory » Research » Research Project #435822

Research Project: Total Proanthocyanidin (PAC) Content and A-type and B-type Ratios of Commercial Cranberry Dietary Supplements

Location: Methods and Application of Food Composition Laboratory

Project Number: 8040-52000-068-049-S
Project Type: Non-Assistance Cooperative Agreement

Start Date: Aug 31, 2019
End Date: Aug 30, 2023

Expanded food composition data and research focused in ongoing ARS programs will be established through studies on the changing composition of the U.S. food supply. Emerging nutrients of public health importance will be studied and data will be included in USDA food and dietary supplement composition databases. For this project, the objectives are to determine total proanthocyanidins (PACs) in cranberry dietary supplements and to determine the fraction of A-type linkages in the PAC oligomers.

PAC content will be determined in commercial cranberry products using 4-di-methylaminocinnamaldehyde (DMAC), high performance liquid chromatography (HPLC) and mass spectrometry (MS) methods. ARS will work with CPS to optimize methods of analysis and quality control protocols. Results for PAC content (including the ratio of A-type to B-type PACs) will be compared among methods and laboratories.