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ARS Home » Midwest Area » Madison, Wisconsin » Vegetable Crops Research » Research » Research Project #435487

Research Project: Evaluation of Heavy Metals as Inadvertent Drivers of Insecticide Resistance Through Activation of Insecticide Detoxification Mechanisms

Location: Vegetable Crops Research

Project Number: 5090-21220-005-20-S
Project Type: Non-Assistance Cooperative Agreement

Start Date: Sep 15, 2018
End Date: Sep 14, 2019

Objective:
Characterize the potential for synergy between metal-based agro-chemicals and other fungicides, to impart cross-resistance on selected populations of the Colorado potato beetle.

Approach:
From populations of beetles collected in potato fields, we will further investigate genetic biomarkers for over-regulation of resistance mechanisms in select populations where we have known history of extreme resistance (eastern U.S.) in comparison to populations where insecticide susceptibility remains high (western U.S.). Further, the same genetic responses observed in ARS laboratory investigations might not be seen within populations obtained from other locations due to the evolution and heterogeneity of the insects, but we can use the extracted RNA for later RNAseq analyses to determine the over-expressed genes in future investigations.