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ARS Home » Plains Area » Clay Center, Nebraska » U.S. Meat Animal Research Center » Nutrition and Environmental Management Research » Research » Research Project #433594

Research Project: Determining if Conventional Beef Cattle Production Practices Contribute to the Development of Antimicrobial Resistance

Location: Nutrition and Environmental Management Research

Project Number: 3040-31000-097-02-T
Project Type: Trust Fund Cooperative Agreement

Start Date: Oct 1, 2017
End Date: Sep 30, 2019

Objective:
The objectives of the research are to investigate environmental transfer of antimicrobial resistance in conventional beef cattle production systems, and to evaluate a novel direct fed microbial as an alternative to antibiotics.

Approach:
ARS investigators at USMARC will conduct studies with beef cattle in which cattle have been raised in the absence or presence of antimicrobials to determine the potential role that dietary and therapeutic antimicrobials may play in the dissemination of antibiotic resistance. ARS scientists will collect samples of cattle ruminal fluid and feces, feedlot surface materials, swabs of cattle hides, and runoff from feedlot pens, and monitor animal performance parameters relative to the production scheme. Samples will be monitored for antibiotic resistant E. coli and Enterococcus by USMARC scientist and a sub-sample provided to UNL for sequencing and antibiotic residue testing. ARS scientists will conduct a study in feedlot cattle to evaluate the benefits of a direct fed microbial to improving animal performance and reducing liver abscesses.