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ARS Home » Northeast Area » Beltsville, Maryland (BARC) » Beltsville Agricultural Research Center » Animal Genomics and Improvement Laboratory » Research » Research Project #433338

Research Project: Improving Feed Efficiency and Environmental Sustainability of Dairy Cattle through Genomics and Novel Technologies

Location: Animal Genomics and Improvement Laboratory

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

Impact of parity differences on residual feed intake estimation in Holstein cows Reprint Icon - (Peer Reviewed Journal)
Cavani, L., Parker Gaddis, K.L., Baldwin, R.L., Santos, J.E., Koltes, J.E., Tempelman, R.J., Vandehaar, M.J., Caputo, M.J., White, H.M., Penagaricano, F., Weigel, K.A. 2023. Impact of parity differences on residual feed intake estimation in Holstein cows. Journal of Dairy Science Communications. https://doi.org/10.3168/jdsc.2022-0307.

Impact of epistasis effects on the accuracy of predicting phenotypic values of residual feed intake in U.S. Holstein cows Reprint Icon - (Peer Reviewed Journal)
Liang, Z., Prakapenka, D., Parker Gaddis, K.L., Vandehaar, M.J., Weigel, K.A., Tempelman, R.J., Koltes, J.E., Santos, J.P., White, H.M., Penagaricano, F., Baldwin, R.L., Da, Y. 2022. Impact of epistasis effects on the accuracy of predicting phenotypic values of residual feed intake in U.S. Holstein cows. Frontiers in Genetics. 13:1017490. https://doi.org/10.3389/fgene.2022.1017490.

Butyrate induces modifications of the CTCF-binding landscape in cattle cells Reprint Icon - (Peer Reviewed Journal)
Boschiero, C., Gao, Y., Baldwin, R.L., Ma, L., Li, C., Liu, G. 2022. Butyrate induces modifications of the CTCF-binding landscape in cattle cells. Biomolecules. 12(9):1177. https://doi.org/10.3390/biom12091177.

Predicting dry matter intake in Canadian Holstein dairy cattle using milk mid-infrared reflectance spectroscopy and other commonly available predictors via artificial neural networks Reprint Icon - (Peer Reviewed Journal)
Shadpour, S., Chud, T.C., Hailemariam, D., Oliveira, H.R., Plastow, G., Stothard, P., Lassen, J., Baldwin, R.L., Miglior, F., Baes, C., Tulpan, D., Schenkel, F.S. 2022. Predicting dry matter intake in Canadian Holstein dairy cattle using milk mid-infrared reflectance spectroscopy and other commonly available predictors via artificial neural networks. Journal of Dairy Science. 105(10):8257–8271. https://doi.org/10.3168/jds.2021-21297.

Multiple-trait random regression modeling of feed efficiency in US Holsteins Reprint Icon - (Peer Reviewed Journal)
Khanal, P., Parker Gaddis, K.L., Vandehaar, M., Weigel, K., White, H., Penagaricano, F., Koltes, J., Santos, J., Baldwin, R.L., Buchard, J., Durr, J., Templeton, R. 2022. Multiple-trait random regression modeling of feed efficiency in US Holsteins. Journal of Dairy Science. 105(7):5954-5971. https://doi.org/10.3168/jds.2021-21739.

Characterization of accessible chromatin regions in cattle rumen epithelial tissue during weaning Reprint Icon - (Peer Reviewed Journal)
Boschiero, C., Gao, Y., Baldwin, R.L., Ma, L., Liu, G.E., Li, C.-J. 2022. Characterization of accessible chromatin regions in cattle rumen epithelial tissue during weaning. Genes. 13:535. https://doi.org/10.3390/genes13030535.

Differential responses of abomasal transcriptome to Haemonchus contortus infection between Haemonchus-selected and Trichostrongylus-selected merino sheep Reprint Icon - (Peer Reviewed Journal)
Liu, J., Zhou, J., Zhao, S., Xu, X., Li, C., Li, L., Shen, T., Hunt, P.W., Zhang, R. 2022. Differential responses of abomasal transcriptome to Haemonchus contortus infection between Haemonchus-selected and Trichostrongylus-selected merino sheep. Parasitology International. 87:102539. https://doi.org/10.1016/j.parint.2022.102539.

Transcriptional reprogramming in rumen epithelium during the developmental transition of pre-ruminant to the ruminant in cattle Reprint Icon - (Peer Reviewed Journal)
Baldwin, R.L., Liu, M., Connor, E.E., Ramsay, T.G., Liu, G., Li, C. 2021. Transcriptional reprogramming in rumen epithelium during the developmental transition of pre-ruminant to the ruminant in cattle. Animals. 11(10):2870. https://doi.org/10.3390/ani11102870.

Synthetic alkaloid treatment influences the intestinal epithelium and mesenteric adipose transcriptome in Holstein steers Reprint Icon - (Peer Reviewed Journal)
McLean, K.J., Baldwin, R.L., Li, C., Klotz, J.L., Edwards, J.L., McLeod, K.R. 2020. Synthetic alkaloid treatment influences the intestinal epithelium and mesenteric adipose transcriptome in Holstein steers. Frontiers in Veterinary Science. 7. Article 615. https://doi.org/10.3389/fvets.2020.00615.

The profiling of DNA methylation and its regulation on divergent tenderness in Angus beef cattle Reprint Icon - (Peer Reviewed Journal)
Zhao, C., Ji, G., Carrillo, J.A., Li, Y., Tian, F., Baldwin, R.L., Zan, L., Song, J. 2020. The profiling of DNA methylation and its regulation on divergent tenderness in Angus beef cattle. Frontiers in Genetics. 11:939. https://doi.org/10.3389/fgene.2020.00939.

Establishment and transcriptomic analyses of a cattle rumen epithelial primary cells (REPC) culture by bulk and single-cell RNA sequencing to elucidate interactions of butyrate and rumen development Reprint Icon - (Peer Reviewed Journal)
Lin, S., Fang, L., Kang, X., Liu, S., Liu, M., Connor, E.E., Baldwin, R.L., Liu, G., Li, C. 2020. Establishment and transcriptomic analyses of a cattle rumen epithelial primary cells (REPC) culture by bulk and single-cell RNA sequencing to elucidate interactions of butyrate and rumen development. Heliyon. 6(6):e041123. https://doi.org/10.1016/j.heliyon.2020.e04112.

Epigenomic profiling of histone marks and CTCF binding sites in bovine rumen epithelial primary cells before and after butyrate treatment Reprint Icon - (Peer Reviewed Journal)
Kang, X., Liu, S., Fang, L., Lin, S., Liu, M., Baldwin, R.L., Liu, G., Li, C. 2020. Epigenomic profiling of histone marks and CTCF binding sites in bovine rumen epithelial primary cells before and after butyrate treatment. Data in Brief. 28:104983. https://doi.org/10.1016/j.dib.2019.104983.

Functional annotation of the cattle genome through systematic discovery and characterization of chromatin states and butyrate-induced variations Reprint Icon - (Peer Reviewed Journal)
Fang, L., Liu, S., Liu, M., Kang, X., Lin, S., Li, B., Connor, E.E., Baldwin, R.L., Tenesa, A., Ma, L., Liu, G., Li, C. 2019. Functional annotation of the cattle genome through systematic discovery and characterization of chromatin states and butyrate-induced variations. BMC Biology. 17(1):68. https://doi.org/10.1186/s12915-019-0687-8.

Transcriptomic profiling of duodenal epithelium reveals temporally dynamic impacts of direct duodenal starch-infusion during dry period of dairy cattle Reprint Icon - (Peer Reviewed Journal)
Li, C., Lin, S., Ranilla-Garcia, M.J., Baldwin, R.L. 2019. Transcriptomic profiling of duodenal epithelium reveals temporally dynamic impacts of direct duodenal starch-infusion during dry period of dairy cattle. Frontiers in Veterinary Science. 6:214. https://doi.org/10.3389/fvets.2019.00214.

Defining the optimal period length and stage of growth or lactation to estimate residual feed intake in dairy cows Reprint Icon - (Peer Reviewed Journal)
Connor, E.E., Hutchison, J.L., Van Tassell, C.P., Cole, J.B. 2019. Defining the optimal period length and stage of growth or lactation to estimate residual feed intake in dairy cows. Journal of Dairy Science. 102(7):6131–6143. https://doi.org/10.3168/jds.2018-15407.

Identification of a novel antisense RNA GHR-AS that regulates the expression of GHR in chichen Reprint Icon - (Peer Reviewed Journal)
Lin, S., Zhang, Z., Xie, T., Hu, B., Ruan, Z., Zhang, L., Li, C., Li, C.C., Nie, Q., Zhang, X. 2019. Identification of a novel antisense RNA GHR-AS that regulates the expression of GHR in chichen. RNA Biology. 14:1-13. https://doi.org/10.1080/15476286.2019.1572440.

Effect of milking frequency and alpha-tocopherol plus selenium supplementation on sheep milk lipid composition and oxidative stability Reprint Icon - (Peer Reviewed Journal)
Pulido, E., Fernandez, M., Prieto, N., Baldwin, R.L., Andres, S., Lopez, S., Giraldez, F.J. 2019. Effect of milking frequency and alpha-tocopherol plus selenium supplementation on sheep milk lipid composition and oxidative stability. Journal of Dairy Science. 102(4):3097-3109. https://doi.org/10.3168/jds.2018-15456.

Epigenetics and heritable phenotypic variations in livestock Reprint Icon - (Book / Chapter)
Lin, S., Fang, L., Li, C., Liu, G. 2019. Epigenetics and heritable phenotypic variations in livestock. In: Tollefsbol T. (editor). Transgenerational Epigenetics. 2nd edition. Amsterdam, Netherlands: Elsevier, p. 283-313

Global transcriptome analysis during adipogenic differentiation and involvement of Transthyretin gene in adipogenesis in cattle Reprint Icon - (Peer Reviewed Journal)
Cai, H., Li, M., Sun, X., Plath, M., Li, C., Lan, X., Lei, C., Huang, Y., Bai, Y., Qi, X., Lin, F., Chen, H. 2018. Global transcriptome analysis during adipogenic differentiation and involvement of Transthyretin gene in adipogenesis in cattle. Frontiers in Genetics. 9:463. https://doi.org/10.3389/fgene.2018.00463.

Integrative analysis of transcriptome and epigenome data enhances the understanding of the genetic basis underlying rumen development - (Abstract Only)

Transcriptomic impacts of rumen epithelium induced by butyrate infusion in dairy cattle in dry period - (Abstract Only)

Effect of consuming endophyte-infected fescue seed on transcript abundance in the mammary gland of lactating and dry cows, as assessed by RNA sequencing Reprint Icon - (Peer Reviewed Journal)
Capuco, A.V., Bickhart, D.M., Li, C., Clover, C.M., Choudhary, R., Grossi, P., Bertoni, G., Trevisi, E., Aiken, G.E., Mcleod, K.R., Baldwin, R.L. 2018. Effect of consuming endophyte-infected fescue seed on transcript abundance in the mammary gland of lactating and dry cows, as assessed by RNA sequencing. Journal of Dairy Science. 101(11):10478–10494. https://doi.org/10.3168/jds.2018-14735.

A progress report for the efficient dairy genome project - (Abstract Only)
Miglior, F., Baes, C., Canovas, A., Coffey, M., Connor, E.E., De Pauw, M., Goddard, E., Hailu, G., Lasson, J., Malchiodi, F., Osborne, V., Pryce, J.E., Sargolzaei, M., Schenkel, F., Wall, E., Wang, Z., Wegman, S., Wright, T., Stothard, P. 2018. A progress report for the efficient dairy genome project [abstract]. American Society of Animal Science and Canadian Society of Animal Science Annual Meeting. Paper No. 324.

Assembly and analysis of changes in transcriptomes of dairy cattle rumen epithelial during lactation and dry periods Reprint Icon - (Peer Reviewed Journal)
Baldwin, R.L., Li, C., Li, R.W. 2018. Assembly and analysis of changes in transcriptomes of dairy cattle rumen epithelial during lactation and dry periods. Agricultural Sciences. 9:619-638. https://doi.org/10.4236/as.2018.95043.

Common on-farm dietary and productions parameters may be used to discrimate between high and low efficiency lactating dairy cows - (Abstract Only)
Iwaniuk, M., Connor, E.E., Erdman, R.A. 2018. Common on-farm dietary and productions parameters may be used to discrimate between high and low efficiency lactating dairy cows [abstract]. In: Proceedings of the 32nd Annual Symposium of the Department of Animal and Avian Sciences, College Park, MD. p. 5-16.

Growth hormone receptor mutations related to individual dwarfism Reprint Icon - (Review Article)
Lin, S., Li, C., Li, C.Z., Zhang, X. 2018. Growth hormone receptor mutations related to individual dwarfism. International Journal of Molecular Sciences. 19(5):1433. https://doi.org/10.3390/ijms19051433.

Profiling of transcriptome responses of the intestinal epithelium to starch hydrolysate direct infusion using RNA-seq technology Reprint Icon - (Abstract Only)
Li, C., Baldwin, R.L. 2018. Profiling of transcriptome responses of the intestinal epithelium to starch hydrolysate direct infusion using RNA-seq technology. Journal of Animal Science. 96(Suppl_3):425. https://doi.org/10.1093/jas/sky404.931.

Transcriptomic impacts of rumen epithelium induced by butyrate infusion in dairy cattle in dry period Reprint Icon - (Peer Reviewed Journal)
Baldwin, R.L., Li, R.W., Jia, Y., Li, C. 2018. Transcriptomic impacts of rumen epithelium induced by butyrate infusion in dairy cattle in dry period. Gene Regulation and Systems Biology. 12:1–11. https://doi.org/10.1177/1177625018774798.