Project Number: 8072-42000-080-02-N
Project Type: Non-Funded Cooperative Agreement
Start Date: Aug 1, 2017
End Date: Jul 31, 2020
Develop an analytical technique capable of detecting antibiotic resistant signature ions directly from solution without any sample preparation. This technique would allow immediate antimicrobial resistance determination and have the ability to screen greater numbers of samples in comparison to established analytical techniques.
Experiments and data analysis on an aminoglycoside solution inoculated with a resistant bacterium. Following a short incubation time, the bacterium containing solution will be spun down just prior to laser vaporization to detect signature antibiotic resistant biomarkers and/or metabolites.