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Research Project: Distinct Regulatory Functions of the TRI6 and TRI10 Genes in DON Biosynthesis

Location: National Programs

Project Number: 0500-00053-004-34-G
Project Type: Grant

Start Date: Jun 1, 2017
End Date: May 31, 2021

Determine the functional relationship between TRI6 and TRI10 and characterize molecular mechanisms involved in the regulation of DON production by pH, nitrogen metabolism, and cAMP signaling.

Further characterize the interaction between TRI6 and TRI10. Identify the Tri10-binding sites and characterize its possible non-TF function in the toxisome. Use site-directly mutagenesis approach to determine the role of conserved PacC-binding sites in the TRI6 and TRI10 promoters.