Location: Virus and Prion Research
Project Number: 5030-32000-120-017-I
Project Type: Interagency Reimbursable Agreement
Start Date: Jul 17, 2017
End Date: Jul 16, 2019
Objective:
Identify viruses through the USDA Influenza A virus swine surveillance system for in vitro and in vivo characterization.
Approach:
From the sequence analysis of viruses isolated from the USDA IAV-S Surveillance, viruses with unique genetic characteristics will be selected for associated in vitro and in vivo study. Additionally, influenza A virus isolates may be identified through public health investigations of zoonotic transmission events or from the animal health sector for unusual phenotypes or evasion of vaccine immunity. The studies funded in this interagency agreement include in vivo and in vitro pathogenesis and transmission, antigenic characterization, or vaccine protection experiments.
