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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Virus and Prion Research » Research » Research Project #432741

Research Project: Characterization of Virus Isolates from the USDA Swine Influenza A Virus Surveillance System

Location: Virus and Prion Research

Project Number: 5030-32000-120-17-I
Project Type: Interagency Reimbursable Agreement

Start Date: Jul 17, 2017
End Date: Jul 16, 2019

Objective:
Identify viruses through the USDA Influenza A virus swine surveillance system for in vitro and in vivo characterization.

Approach:
From the sequence analysis of viruses isolated from the USDA IAV-S Surveillance, viruses with unique genetic characteristics will be selected for associated in vitro and in vivo study. Additionally, influenza A virus isolates may be identified through public health investigations of zoonotic transmission events or from the animal health sector for unusual phenotypes or evasion of vaccine immunity. The studies funded in this interagency agreement include in vivo and in vitro pathogenesis and transmission, antigenic characterization, or vaccine protection experiments.