Research Project: Immune, Molecular, and Ecological Approaches for Attenuating GI Nematode Infections of Ruminants

Location: Animal Parasitic Diseases Laboratory

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Infection, genetics, and evolution of Trichinella: Historical insights and applications - (Peer Reviewed Journal)
Bilska-Zajak, E., Thompson, P.C., Rosenthal, B.M., Rozycki, M., Cencek, T. 2021. Infection, genetics, and evolution of Trichinella: Historical insights and applications. Infection, Genetics and Evolution. 95:105080. https://doi.org/10.1016/j.meegid.2021.105080.

FcRn-targeted mucosal vaccination protects the respiratory tract from influenza virus infection - (Peer Reviewed Journal)

Genetic evidence substantiates transmission of Trichinella spiralis from one swine farm to another - (Peer Reviewed Journal)
Bilska-Zajac, E., Tonanzi, D., Pozio, E., Rozycki, M., Cencek, T., Thompson, P.C., Rosenthal, B.M., La Rosa, G. 2021. Genetic structure uniformity substantiates transmission of Trichinella spiralis from one swine farm to another. Parasites & Vectors. 14:359. https://doi.org/10.1186/s13071-021-04861-9.

Repeated, drug-truncated infections with Ostertagia ostertagi elicit strong humoral and cell-mediated immune responses - (Peer Reviewed Journal)
Tuo, W., Zarlenga, D.S., Bakshi, M., Vinyard, B.T. 2021. Repeated, drug-truncated infections with Ostertagia ostertagi elicit strong humoral and cell-mediated immune responses. Veterinary Parasitology. 296:109510. https://doi.org/10.1016/j.vetpar.2021.109510.

A simple method for identifying and quantifying gastrointestinal nematodes of cattle - (Peer Reviewed Journal)
Zarlenga, D.S., Barone, C., Hebert, D.A., Santin, M., Newcomb, H. 2021. A simple method for identifying and quantifying gastrointestinal nematodes of cattle. Parasitology Research. 120(12):3979-3986. https://doi.org/10.1007/s00436-021-07340-3.

Ostertagia ostertagi mediates early host immune responses via macrophage and Toll like receptor pathways - (Peer Reviewed Journal)
Bakshi, M., Hebert, D.A., Gulbronson, C., Bauchan, G.R., Tuo, W., Zarlenga, D.S. 2021. Ostertagia ostertagi mediates early host immune responses via macrophage and Toll like receptor pathways. Infection and Immunity. 1-42. https://doi.org/10.1128/IAI.00017-21.

Gastrointestinal parasites of a reintroduced semi-wild Plains bison (Bison bison bison) herd: Examining effects of demographic variation, deworming treatments, and management strategy - (Peer Reviewed Journal)
Wiese, J.D., Caven, A.J., Zarlenga, D.S., Topliff, C.L. 2021. Gastrointestinal parasites of a reintroduced semi-wild Plains bison (Bison bison bison) herd: Examining effects of demographic variation, deworming treatments, and management strategy. International Journal of Parasitology. 14:216-227. https://doi.org/10.1016/j.ijppaw.2021.02.004.

Divergence at mitochondrial and ribosomal loci indicates the split between Asian and European populations of Trichinella spiralis occurred prior to swine domestication - (Peer Reviewed Journal)
Thompson, P.C., Bilzka-Zajac, E., Zarlenga, D.S., Mingyuan, L., Cencek, T., Rozyicki, M., Rosenthal, B.M. 2021. Divergence at mitochondrial and ribosomal loci indicates the split between Asian and European populations of Trichinella spiralis occurred prior to swine domestication. Infection, Genetics and Evolution. 88(104705). https://doi.org/10.1016/j.meegid.2021.104705.

Trichinella species and genotypes - (Review Article)
Zarlenga, D.S., Thompson, P.C., Pozio, E. 2020. Trichinella species and genotypes. Research in Veterinary Science. 133:289-296. https://doi.org/10.1016/j.rvsc.2020.08.012.

Assessing the evolutionary persistence of ecological relationships: a review and preview - (Review Article)
Hecht, L.B., Thompson, P.C., Rosenthal, B.M. 2020. Assessing the evolutionary persistence of ecological relationships: a review and preview. Infection, Genetics and Evolution. 84(1-11). https://doi.org/10.1016/j.meegid.2020.104441.

Editorial: Immunoparasitology: A unique interplay between host and pathogen - (Peer Reviewed Journal)
Suo, X., Wu, Z., Lillehoj, H.S., Tuo, W. 2020. Editorial: Immunoparasitology: A unique interplay between host and pathogen. Frontiers in Immunology. 11:880. https://doi.org/10.3389/fimmu.2020.00880.

Immunoproteomic and mass spectrometric analysis of Eimeria acervulina antigens recognized by antisera from chickens infected with E. acervulina, E. tenella or E. necatrix - (Peer Reviewed Journal)
Liu, J., Tuo, W., Wu, X., Xiong, J., Yu, E., Yin, C., Ma, Z., Liu, L. 2020. Immunoproteomic and mass spectrometric analysis of Eimeria acervulina antigens recognized by antisera from chickens infected with E. acervulina, E. tenella or E. necatrix. Veterinary Parasitology. 13:93. https://doi.org/10.1186/s13071-020-3965-y.

Wild ruminants as reservoirs of domestic livestock gastrointestinal nematodes - (Peer Reviewed Journal)
Barone, C.D., Wit, J., Gilleard, J.S., Hoberg, E.P., Zarlenga, D.S. 2020. Wild ruminants as reservoirs of domestic livestock gastrointestinal nematodes. Veterinary Parasitology. https://doi.org/10.1016/j.vetpar.2020.109041.

Characterization of IL-10-producing neutrophils in cattle infected with Ostertagia ostertagi - (Peer Reviewed Journal)
Li, L., Si, H., Wu, S., Mendez, J.O., Zarlenga, D.S., Tuo, W., Xiao, Z. 2019. Characterization of IL-10 producing neutrophils in cattle infected with Ostertagia ostertagi. Scientific Reports. 9:20292. https://doi.org/10.1038/s41598-019-56824-x.

Recommendations for genotyping Trichinella muscle stage larvae - (Peer Reviewed Journal)
Pozio, E., Zarlenga, D.S. 2019. Recommendations for genotyping Trichinella muscle stage larvae. Food and Waterborne Parasitology. 15:e00033. https://doi.org/10.1016/j.fawpar.2018.e00033.

TRPV4 is dispensable for the development of airway allergic asthma - (Peer Reviewed Journal)
Palaniyandi, S., Rajendrakumar, A.M., Periasamy, S., Goswami, R., Tuo, W., Zhu, X., Rahaman, S.O. 2019. TRPV4 is dispensable for the development of airway allergic asthma. Laboratory Investigation. https://doi.org/10.1038/s41374-019-0305-y.

Bovine neutrophils form extracellular traps in response to the gastrointestinal parasite Ostertagia ostertagi - (Peer Reviewed Journal)
Mendez, J., Sun, D., Tuo, W., Zhengguo, X. 2018. Bovine neutrophils form extracellular traps in response to the gastrointestinal parasite Ostertagia ostertagi. Scientific Reports. 8:17598. https://doi.org/10.1038/s41598-018-36070-3

A tale of three kingdoms: members of the Phylum Nematoda independently acquired the detoxifying enzyme cyanase through horizontal gene transfer from plants and bacteria - (Peer Reviewed Journal)
Zarlenga, D.S., Mitreva, M., Thompson, P., Tyagi, R., Tuo, W., Hoberg, E.P. 2018. A tale of three kingdoms: members of the Phylum Nematoda independently acquired the detoxifying enzyme cyanase through horizontal gene transfer from plants and bacteria. Parasitology. 146(4):445-452. https://doi.org/10.1017/S0031182018001701.

Museum metabarcoding: A novel method revealing gut helminth communities of small mammals across space and time - (Peer Reviewed Journal)
Greiman, S., Cook, J., Tkach, V., Hoberg, E.P., Menning, D., Hope, A., Sonsthagen, S., Talbot, S. 2018. Museum metabarcoding: A novel method revealing gut helminth communities of small mammals across space and time. International Journal for Parasitology. 48(13):1061-1070. https://doi.org/10.1016/j.ijpara.2018.08.001.

Host use dynamics in a heterogeneous fitness landscape generates oscillations and diversification - (Peer Reviewed Journal)
Braga, M.P., Araujo, S.B., Agosta, S., Brooks, D., Hoberg, E.P., Nylin, S., Janz, N., Boeger, W.A. 2018. Host use dynamics in a heterogeneous fitness landscape generates oscillations and diversification. Evolution. https://doi.org/10.1111/evo.13557.

Diversity of gastrointestinal helminths in Dall's sheep and the negative association of the abomasal nematode, Marshallagia marshalli, with fitness indicators - (Peer Reviewed Journal)
Aleuy, O., Ruckstuhl, K., Hoberg, E.P., Veitch, A., Simmons, N., Kutz, S. 2018. Diversity of gastrointestinal helminths in Dall's sheep and the negative association of the abomasal nematode, Marshallagia marshalli, with fitness indicators. International Journal for Parasitology. 13:3. https://doi.org/10.1371/journal.pone.0192825

Embracing colonizations: A new paradigm for species association dynamics - (Peer Reviewed Journal)
Nylin, S., Agosta, S., Bensch, S., Boeger, W.A., Braga, M., Brooks, D.R., Forister, M.L., Hamback, P.A., Hoberg, E.P., Nyman, T., Schapers, A., Stigall, A. 2018. Embracing colonizations: A new paradigm for species association dynamics. Trends in Ecology and Evolution. 33(1):4-14. https://doi.org/10.1016/j.tree.2017.10.005

A new worm infiltrating the human cornea: A report of 3 cases - (Peer Reviewed Journal)
Mcburney-Lin, S., Khorram, D., Gee, S., Hoberg, E.P., Klassen-Fischer, M., Neafie, R. 2018. A new worm infiltrating the human cornea: A report of 3 cases. Journal of Ophthalmology. 9:124-130. doi:10.1016/j.ajoc.2018.01.013

The Beringian Coevolution Project: Holistic collections of mammals and associated parasites reveal novel perspectives on changing environments in the north - (Peer Reviewed Journal)
Cook, J.A., Galbreath, K.E., Bell, K.C., Campbell, M.L., Carriere, S., Colella, J.P., Dawson, N.G., Dunnum, J.L., Eckerlin, R.P., Geriman, S.E., Fedorov, V., Haas, G.M., Haukisalmi, V., Henttonen, H., Hope, A.G., Jackson, D., Jung, T., Koehler, A., Kinsella, M., Krejsa, D., Kutz, S.J., Liphardt, S., Macdonald, S.O., Malaney, J.L., Makarikov, A., Martin, J., Mclean, B., Mulders, R., Batsaikhan, N., Talbot, S.L., Tkach, V., Tsvetkova, A., Toman, H.M., Waltari, E., Whitman, J., Hoberg, E.P. 2016. The Beringian Coevolution Project: Holistic collections of mammals and associated parasites reveal novel perspectives on changing environments in the north. Arctic Science. doi.org/10.1139/as-2016-0042.