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ARS Home » Southeast Area » Oxford, Mississippi » Natural Products Utilization Research » Research » Research Project #430871

Research Project: Discovery and Development of Natural Products for Pharmaceutical and Agrichemical Applications II

Location: Natural Products Utilization Research

Project Number: 6060-41000-012-06-S
Project Type: Non-Assistance Cooperative Agreement

Start Date: May 2, 2016
End Date: Apr 30, 2021

Objective:
The overall goal of this project is to discover, develop and foster commercialization of new bioactive products as new pharmaceuticals or agrichemicals, and to identify, characterize and develop plants for production of pharmaceuticals or pesticides as potential alternative crops.

Approach:
(1) Development of strategies for rational collection of terrestrial, aquatic and marine plants, as well as microbes, as a source of novel bioactive natural products. (2) Discovery and development of novel pharmaceutically or agriculturally useful natural products from higher plants. (3) Identification and investigation of new mechanistic targets that may be used in the discovery of pesticides and antiinfective and anti-cancer agents. (4) Development of natural product-based approaches and technologies to overcome resistance to antibiotics and chemotherapeutic agents. (5) Investigations of selections, cloning, propagation, agronomics, cultivation, harvesting and processing of medicinal plants in relation to the chemistry of desired pharmaceutically or agriculturally useful natural products.