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ARS Home » Northeast Area » Boston, Massachusetts » Jean Mayer Human Nutrition Research Center On Aging » Research » Research Project #427211

Research Project: Molecular Targets of Tomato Carotenoids and their Metabolites in Cancer Prevention

Location: Jean Mayer Human Nutrition Research Center On Aging

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

Dietary tomato powder inhibits high fat diet-promoted hepatocellular carcinoma with alteration of gut microbiota in mice lacking carotenoid cleavage enzymes Reprint Icon - (Peer Reviewed Journal)
Xia, H., Liu, C., Li, C., Fu, M., Takahashi, S., Hu, K., Aizawa, K., Hiroyuki, S., Wu, G., Zhao, L., Wang, X. 2018. Dietary tomato powder inhibits high fat diet-promoted hepatocellular carcinoma with alteration of gut microbiota in mice lacking carotenoid cleavage enzymes. Cancer Prevention Research. https://doi.org/10.1158/1940-6207.CAPR-18-0188.

Carotenoids - (Book / Chapter)
Mernitz, H., Wang, X. 2016. Carotenoids. In: Schwab, M., editor. Encylopedia of Cancer. 3rd edition. Berlin, Germany: Springer-Verlag. p. 669-672.

Tobacco carcinogen (NNK) induces both lung cancer and non-alcoholic steatohepatitis and hepatocellular carcinomas in ferrets which can be attenuated by lycopene supplementation - (Peer Reviewed Journal)
Aizawa, K., Liu, C., Tang, S., Veeramachaneni, S., Hu, K., Smith, D.E., Wang, X. 2016. Tobacco carcinogen (NNK) induces both lung cancer and non-alcoholic steatohepatitis and hepatocellular carcinomas in ferrets which can be attenuated by lycopene supplementation. International Journal of Cancer. doi: 10.1002/ijc.3016.

Deletion of tumor progression locus 2 attenuates alcohol induced hepatic inflammation - (Peer Reviewed Journal)
Stice, C.P., Hussain, S., Liu, C., Ausman, L., Wang, X., Greenberg, A. 2016. Deletion of tumor progression locus 2 attenuates alcohol induced hepatic inflammation. Hepatobiliary Surgery and Nutrition. 5(1):29-37.

Tumor progression locus 2 ablation suppressed hepatocellular carcinoma development by inhibiting hepatic inflammation and steatosis in mice - (Peer Reviewed Journal)
Li, X., Liu, C., Ip, B.C., Hu, K., Smith, D.E., Greenberg, A., Wang, X. 2015. Tumor progression locus 2 ablation suppressed hepatocellular carcinoma development by inhibiting hepatic inflammation and steatosis in mice. Journal of Experimental and Clinical Cancer Research. 34:138. doi: 10.1186/s13046-015-0254-2.

Isocaloric pair-fed high-carbohydrate diet induced more hepatic steatosis and inflammation than high-fat diet mediated by miR- 34a/SIRT1 axis in mice - (Peer Reviewed Journal)
Li, X., Lian, F., Liu, C., Hu, K., Wang, X. 2015. Isocaloric pair-fed high-carbohydrate diet induced more hepatic steatosis and inflammation than high-fat diet mediated by miR- 34a/SIRT1 axis in mice. Scientific Reports. 5:16774. doi: 10.1038/srep16774.