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ARS Home » Pacific West Area » Davis, California » Western Human Nutrition Research Center » Obesity and Metabolism Research » Research » Research Project #426826

Research Project: Improving Public Health by Understanding Diversity in Diet, Body, and Brain Interactions

Location: Obesity and Metabolism Research

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

Blood levels of endocannabinoids, oxylipins, and metabolites are altered in hemodialysis patients Reprint Icon - (Peer Reviewed Journal)
Watkins, B.A., Friedman, A.N., Kim, J., Borkowski, K., Kaiser, S., Fiehn, O., Newman, J.W. 2022. Blood levels of endocannabinoids, oxylipins, and metabolites are altered in hemodialysis patients. International Journal of Molecular Sciences. 23(17). https://doi.org/10.3390/ijms23179781.

Obesogenic and diabetic effects of CD44 in mice are sexually dimorphic and dependent on genetic background Reprint Icon - (Peer Reviewed Journal)
VerHague, M., Albright, J., Barron, K., Kim, M., Bennett, B.J. 2022. Obesogenic and diabetic effects of CD44 in mice are sexually dimorphic and dependent on genetic background. Biology of Sex Differences. 13. Article 14. https://doi.org/10.1186/s13293-022-00426-2.

Dissecting the genetic architecture of cystatin C in diversity outbred mice Reprint Icon - (Peer Reviewed Journal)
Huda, N.M., Verhague, M., Albright, J., Smallwood, T., Bell, T., Que, E., Miller, D., Roshanravan, B., Allayee, H., Manuel De Villena, F., Bennett, B.J. 2020. Dissecting the genetic architecture of cystatin C in diversity outbred mice. Genes, Genomes, and Genomics. 10(7):2529-2541. https://doi.org/10.1534/g3.120.401275.

Comparative analysis of obesity-related cardiometabolic and renal biomarkers in human plasma and serum Reprint Icon - (Peer Reviewed Journal)
Rajan, M., Sotak, M., Barrenas, F., Shen, T., Borkowski, K., Ashton, N., Biorserud, C., Lindahl, T.L., Ramstrom, S., Scholl, M., Lindahl, P., Fiehn, O., Newman, J.W., Perkins, R., Wallenius, V., Lange, S., Borgeson, E. 2019. Comparative analysis of obesity-related cardiometabolic and renal biomarkers in human plasma and serum. Scientific Reports. 9. https://doi.org/10.1038/s41598-019-51673-0.

Acute hypercapnia/ischemia alters the esterification of arachidonic acid and docosahexaenoic acid epoxide metabolites in rat brain neutral lipids Reprint Icon - (Peer Reviewed Journal)
Otoki, Y., Metherel, A.H., Pedersen, T., Yang, J., Hammock, B.D., Bazinet, R.P., Newman, J.W., Taha, A.Y. 2019. Acute hypercapnia/ischemia alters the esterification of arachidonic acid and docosahexaenoic acid epoxide metabolites in rat brain neutral lipids. Lipids. 55(1):7-22. https://doi.org/10.1002/lipd.12197.

Prospective randomized controlled pilot study on the effects of almond consumption on skin lipids and wrinkles Reprint Icon - (Peer Reviewed Journal)
Foolad, N., Vaughn, A.R., Rybak, I., Burney, W., Chodur, G., Newman, J.W., Steinberg, F.M., Sivamani, R.K. 2019. Prospective randomized controlled pilot study on the effects of almond consumption on skin lipids and wrinkles. Phytotherapy Research. 33(12):3212-3217. https://doi.org/10.1002/ptr.6495.

Predicting the effects of supplemental EPA and DHA on the omega-3 index Reprint Icon - (Peer Reviewed Journal)
Walker, R.E., Harris Jackson, K., Tintle, N.L., Shearer, G.C., Bernasconi, A., Masson, S., Latini, R., Heydari, B., Kwong, R.Y., Flock, M., Kris-Etherton, P., Nedergaard Hedengran, A., Carney, R.M., Skulas-Ray, A., Gidding, S.S., Dewell, A., Gardner, C., Grenon, M.S., Sarter, B., Newman, J.W., Pedersen, T.L., Larson, M., Harris, W.S. 2019. Predicting the effects of supplemental EPA and DHA on the omega-3 index. American Journal of Clinical Nutrition. 110(4):1034-1040. https://doi.org/10.1093/ajcn/nqz161.

A Mediterranean-style eating pattern lower in lean red meat reduced plasma trimethylamine N-oxide in adults classified as overweight or obese Reprint Icon - (Abstract Only)
Gertz, E.R., Wang, Y., O'Connor, L., Campbell, W.W., Bennett, B.J. 2019. A Mediterranean-style eating pattern lower in lean red meat reduced plasma trimethylamine N-oxide in adults classified as overweight or obese. Meeting Abstract. 3(1). https://doi.org/10.1093/cdn/nzz044.P08-030-19.

A randomized controlled-feeding trial based on the Dietary Guidelines for Americans does not affect plasma trimethylamine N-oxide levels in women Reprint Icon - (Abstract Only)
Gertz, E.R., Krishnan, S., Peerson, J.M., Adams, S.H., Laugero, K.D., Newman, J.W., Keim, N.L., Bennett, B.J. 2019. A randomized controlled-feeding trial based on the Dietary Guidelines for Americans does not affect plasma trimethylamine N-oxide levels in women. Meeting Abstract. (3)1. https://doi.org/10.1093/cdn/nzz044.P08-031-19.

Oxylipins in triglyceride-rich lipoproteins of dyslipidemic subjects promote endothelial inflammation following a high fat meal Reprint Icon - (Peer Reviewed Journal)
Rajamani, A., Borkowski, K., Akre, S., Fernandez, A., Newman, J.W., Simon, S.I., Passerini, A.G. 2019. Oxylipins in triglyceride-rich lipoproteins of dyslipidemic subjects promote endothelial inflammation following a high fat meal. Scientific Reports. 9:8655. https://doi.org/10.1038/s41598-019-45005-5.

MS-based targeted metabolomics of eicosanoids and other oxylipins: analytical and inter-individual variabilities Reprint Icon - (Peer Reviewed Journal)
Gladine, C., Ostermann, A.I., Newman, J.W., Schebb, N.H. 2019. MS-based targeted metabolomics of eicosanoids and other oxylipins: analytical and inter-individual variabilities. Journal of Free Radical Biology and Medicine. 144:72-89. https://doi.org/10.1016/j.freeradbiomed.2019.05.012.

The role of the gut microbiome in predicting response to diet and the development of precision nutrition models. Part II: Results Reprint Icon - (Review Article)
Riley, H.L., Kable, M.E., Marco, M.L., Keim, N.L. 2019. The role of the gut microbiome in predicting response to diet and the development of precision nutrition models. Part II: Results. Advances in Nutrition. https://doi.org/10.1093/advances/nmz049.

Walnuts change lipoprotein composition suppressing TNFa-stimulated cytokine production by diabetic adipocyte Reprint Icon - (Peer Reviewed Journal)
Borkowski, K., Yim, S.J., Holt, R.R., Hackman, R.M., Keen, C.L., Newman, J.W., Shearer, G.C. 2019. Walnuts change lipoprotein composition suppressing TNFa-stimulated cytokine production by diabetic adipocyte. Journal of Nutritional Biochemistry. 68:51-58. https://doi.org/10.1016/j.jnutbio.2019.03.004.

Sexual dimorphism of atherosclerosis and plasma lipids: Analysis of complex traits in a diversity outbred F1 mouse population Reprint Icon - (Abstract Only)
Sexual dimorphism of atherosclerosis and plasma lipids: Analysis of complex traits in a diversity outbred F1 mouse population. Meeting Abstract. (39)1. https://doi.org/10.1161/atvb.39.suppl_1.154.

Atherosclerosis susceptibility in the collaborative cross Reprint Icon - (Abstract Only)
Rindy, A., Yam, P., Albright, J., Verhauge, M., Bennett, B.J. 2019. Atherosclerosis susceptibility in the collaborative cross. Arteriosclerosis Thrombosis and Vascular Biology. 38(1). https://doi.org/10.1161/atvb.38.suppl_1.643.

microRNA-146a-5p association with the cardiometabolic disease risk factor TMAO Reprint Icon - (Peer Reviewed Journal)
Coffey, A.R., Smallwood, T.L., Albright, J., Hua, K., Kanke, M., Pomp, D., Bennett, B.J., Sethupathy, P. 2019. microRNA-146a-5p association with the cardiometabolic disease risk factor TMAO. Physiological Genomics. 51(2):59-71. https://doi.org/10.1152/physiolgenomics.00079.2018.

Impact of post-collection freezing delay on the reliability of serum metabolomics in samples reflecting the California mid-term pregnancy biobank Reprint Icon - (Peer Reviewed Journal)
La Frano, M.R., Carmichael, S.L., Ma, C., Hardley, M., Shen, T., Wong, R., Rosales, L., Borlowski, K., Pedersen, T.L., Shaw, G., Stevenson, D.K., Fiehn, O., Newman, J.W. 2018. Impact of post-collection freezing delay on the reliability of serum metabolomics in samples reflecting the California mid-term pregnancy biobank. Metabolomics. 14:151. https://doi.org/10.1007/s11306-018-1450-9.

Diet quality for sodium and vegetables mediate effects of whole food diets on 8-week changes in stress load Reprint Icon - (Peer Reviewed Journal)
Soltani, H., Keim, N.L., Laugero, K.D. 2018. Diet quality for sodium and vegetables mediate effects of whole food diets on 8-week changes in stress load. Nutrients. 10(11):1606. https://doi.org/10.3390/nu10111606.

Does exercise alter gut microbial composition? A systematic review Reprint Icon - (Review Article)
Mitchell, C.M., Davy, B.M., Hulver, M.W., Neilson, A.P., Bennett, B.J., Davy, K.P. 2019. Does exercise alter gut microbial composition? A systematic review. Medicine and Science in Sports and Exercise. 51(1):160-167. https://doi.org/10.1249/MSS.0000000000001760.

Diet induced-obesity and weight loss alter bile acid profiles and gene expression in insulin target tissues Reprint Icon - (Peer Reviewed Journal)
Lafrano, M.R., Hernandez-Carretero, A., Weber, N., Borkowski, K., Pedersen, T.L., Newman, J.W., Osborn, O. 2018. Diet induced-obesity and weight loss alter bile acid profiles and gene expression in insulin target tissues. Nutrition Research. 46:11-21. https://doi.org/10.1016/j.nutres.2017.07.006.

Structural equation modeling of food craving across the menstrual cycle using behavioral, neuroendocrine, and metabolic factors Reprint Icon - (Peer Reviewed Journal)
Krishnan, S., Tryon, R.R., Agrawal, K., Welch, L.C., Horn, W.F., Newman, J.W., Keim, N.L. 2018. Structural equation modeling of food craving across the menstrual cycle using behavioral, neuroendocrine, and metabolic factors. Physiology and Behavior. 195:28-36. https://doi.org/10.1016/j.physbeh.2018.07.011.

Non-invasive profiling of sweat-derived lipid mediators for cutaneous research Reprint Icon - (Review Article)
Agrawal, K., Sivamani, R., Newman, J.W. 2018. Non-invasive profiling of sweat-derived lipid mediators for cutaneous research. Skin Research and Technology. 58:188-195. https://doi: 10.1194/jlr.M071738.

Oral ibuprofen differentially affects plasma and sweat lipid mediator profiles in healthy adult males Reprint Icon - (Peer Reviewed Journal)
Agrawal, K., Bosviel, R., Piccolo, B.D., Newman, J.W. 2018. Oral ibuprofen differentially affects plasma and sweat lipid mediator profiles in healthy adult males. Prostaglandins & Other Lipid Mediators. 137:1-8. https://doi.org/10.1016/j.prostaglandins.2018.05.009.

Effects of atopic dermatitis and gender on sebum lipid mediator and fatty acid profiles Reprint Icon - (Peer Reviewed Journal)
Agrawal, K., Hassoun, L.A., Foolad, N., Pedersen, T.L., Sivamani, R.K., Newman, J.W. 2018. Effects of atopic dermatitis and gender on sebum lipid mediator and fatty acid profiles. Prostaglandins Leukotrienes and Essential Fatty Acids. 134:7-16. https://doi:10.1016/j.plefa.2018.05.001.

Impact of an 8-week controlled feeding trial based on the Dietary Guidelines for Americans on cardiometabolic health indices Reprint Icon - (Peer Reviewed Journal)
Krishnan, S., Adams, S.H., Allen, L.H., Laugero, K.D., Newman, J.W., Stephensen, C.B., Burnett, D.J., Witbracht, M.G., Welch, L.C., Que, E.S., Keim, N.L. 2018. Impact of an 8-week controlled feeding trial based on the Dietary Guidelines for Americans on cardiometabolic health indices. American Journal of Clinical Nutrition. 108(2):266-278. https://doi.org/10.1093/ajcn/nqy113.

Plasma fatty acid ethanolamides are associated with postprandial triglycerides, ApoCIII and ApoE in humans consuming high fructose corn syrup-sweetened beverage Reprint Icon - (Peer Reviewed Journal)
Price, C.A., Argueta, D.A., Medici, V., Bremer, A.A., Lee, V., Nunez, M.V., Chen, G.X., Keim, N.L., Havel, P.J., Stanhope, K.L., Dipatrizio, N.V. 2018. Plasma fatty acid ethanolamides are associated with postprandial triglycerides, ApoCIII and ApoE in humans consuming high fructose corn syrup-sweetened beverage. American Journal of Physiology - Endocrinology and Metabolism. 315(2):E141-E149. https://doi.org/10.1152/ajpendo.00406.2017.

A clear difference emerges in hormone patterns following a standard mid-day meal in regular breakfast eating or breakfast skipping young women Reprint Icon - (Peer Reviewed Journal)
Forester, S.M., Widaman, A.M., Krishnan, S., Witbracht, M.G., Horn, W.F., Laugero, K.D., Keim, N.L. 2018. A clear difference emerges in hormone patterns following a standard mid-day meal in regular breakfast eating or breakfast skipping young women. Journal of Nutrition. 148(5):658-692. https://doi.org/10.1093/jn/nxy020.

A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction Reprint Icon - (Peer Reviewed Journal)
Killion, E.A., Reeves, A.R., El Azzouny, M.A., Yan, Q., Surujon, D., Griffin, J.D., Bowman, T.A., Wang, C., Matthan, N.R., Klett, E.L., Kong, D., Newman, J.W., Han, X., Lee, M., Coleman, R.A., Greenberg, A.S. 2018. A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction. Molecular Metabolism. 9:43-46. https://doi.org/10.1016/j.molmet.2018.01.012.

Adropin: an endocrine link between the biological clock and cholesterol homeostasis. Reprint Icon - (Peer Reviewed Journal)
Ghoshal, S., Stevens, J.R., Billon, C., Giradet, C., Situala, S., Leon, A.S., Rao, D., Skinner, J.S., Rankinen, T., Bouchard, C., Nunez, M.V., Stanhope, K.L., Howatt, D.A., Daugherty, A., Zhang, J., Schuelke, M., Weiss, E.P., Burris, T.P., Havel, P.J., Butler, A.A., Bennett, B.J., Sethupathy, P. 2017. Adropin: an endocrine link between the biological clock and cholesterol homeostasis. Molecular Metabolism. 8:51-64. https://doi.org/10.1016/j.molmet.2017.12.002.

Improving metabolic health through precision dietetics in mice Reprint Icon - (Peer Reviewed Journal)
Barrington, W.T., Wulfridge, P., Gunaratna, R.T., Rojas, C.M., Howe, S.Y., Perry, A., Hua, K., Hansen, K.D., Fuchs-Young, R., Bennett, B.J., Pomp, D., Feinberg, A.P., Threadgill, D.W. 2018. Improving metabolic health through precision dietetics in mice. Genetics. 208:399-417. https://doi.org/10.1534/genetics.117.300536.

Abnormal lipoprotein oxylipins in metabolic syndrome and partial correction by omega-3 fatty acids Reprint Icon - (Peer Reviewed Journal)
Shearer, G.C., Borkowski, K., Puumala, S.L., Harris, W.S., Pedersen, T.L., Newman, J.W. 2017. Abnormal lipoprotein oxylipins in metabolic syndrome and partial correction by omega-3 fatty acids. Prostaglandins Leukotrienes and Essential Fatty Acids. 128:1-10. https://doi.org/10.1016/j.plefa.2017.10.006.

Lack of myeloid Fatp1 increases atherosclerotic lesion size in Ldlr-/- mice Reprint Icon - (Peer Reviewed Journal)
Liyang, Z., Cozzo, A.J., Johnson, A.R., Christensen, T., Freemerman, A.J., Bear, J.E., Rotty, J.D., Bennett, B.J., Makowski, L. 2017. Lack of myeloid Fatp1 increases atherosclerotic lesion size in Ldlr-/- mice. Atherosclerosis. 266:182-189. https://doi.org/10.1016/j.atherosclerosis.2017.10.009.

Effects of stimulation technique, anatomical region and time on human sweat lipid mediator profiles. Reprint Icon - (Peer Reviewed Journal)
Agrawal, K., Waller, J.D., Pedersen, T.L., Newman, J.W. 2017. Effects of stimulation technique, anatomical region and time on human sweat lipid mediator profiles. Prostaglandins & Other Lipid Mediators. 134:84-92. https://doi.org/10.1016/j.prostaglandins.2017.09.007.

Systems genetics identifies a co-regulated module of liver microRNAs associated with plasma LDL cholesterol in murine diet-induced dyslipidemia Reprint Icon - (Peer Reviewed Journal)
Coffey, A.R., Smallwood, T.L., Albright, J., Hua, K., Kanke, M., Pomp, D., Bennett, B.J., Sethupathy, P. 2017. Systems genetics identifies a co-regulated module of liver microRNAs associated with plasma LDL cholesterol in murine diet-induced dyslipidemia. PLoS Genetics. 49(11):618-629. https://doi.org/10.1152/physiolgenomics.00050.2017.

Emotion-Based cognition in mice is differentially influenced by dose and chemical form of dietary docosahexaenoic acid Reprint Icon - (Peer Reviewed Journal)
Laugero, K.D., Adkins, Y.C., Kelley, D.S., Mackey, B.E. 2017. Emotion-Based cognition in mice is differentially influenced by dose and chemical form of dietary docosahexaenoic acid. Nutrients. 9(9):993. https://doi.org/10.3390/nu9090993.

Infant cortisol concentrations do not differ by group in a randomized controlled trial of lipid based nutrient supplements among mothers and infants in Malawi Reprint Icon - (Peer Reviewed Journal)
Stewart, C.P., Oaks, B.M., Ashorn, P., Dewey, K.G., Laugero, K.D. 2017. Infant cortisol concentrations do not differ by group in a randomized controlled trial of lipid based nutrient supplements among mothers and infants in Malawi . Journal of Nutrition. doi: 10.1186:s12884.015.0793.8.

Obesity-induced changes in lipid mediators persist after weight loss Reprint Icon - (Peer Reviewed Journal)
Hernandez-Carretero, A., Weber, N., La Frano, M.R., Ying, M., Lantero Rodriguez, J., Sears, D.D., Wallenius, V., Borgeson, E., Newman, J.W., Osborn, O. 2017. Obesity-induced changes in lipid mediators persist after weight loss. International Journal of Obesity. 46:11-21. https://doi.org/10.1016/j.nutres.2017.07.006.

Associations among fatty acids, desaturase and elongase, and insulin resistance in children Reprint Icon - (Peer Reviewed Journal)
Beccarelil, L.M., Scheer, R.E., Newman, J.W., Borkowska, A.G., Gray, I.J., Linnell, J.D., Keen, C., Young, H. 2017. Associations among fatty acids, desaturase and elongase, and insulin resistance in children. Journal of American College of Nutrition. 37:44-50. https://doi.org/10.1080/07315724.2017.1347908.

Oleocanthal-rich extra virgin olive oil demonstrates acute anti-platelet effects in healthy men in a randomized trial - (Peer Reviewed Journal)
Agrawal, K., Melliou, E., Li, X., Pedersen, T.L., Wang, S.C., Magiatis, P., Newman, J.W., Holt, R.R. 2017. Oleocanthal-rich extra virgin olive oil demonstrates acute anti-platelet effects in healthy men in a randomized trial. Journal of Functional Foods. 36:84-93. doi: 10.1016/j.jff.2017.06.046.

Prebiotic milk oligosaccharides prevent development of obese phenotype, impairment of gut permeability, and microbial dysbiosis in high fat-fed mice Reprint Icon - (Peer Reviewed Journal)
Hamilton, K.M., Ronveaux, C.C., Rust, B., Newman, J.W., Hawley, M., Barile, D., Mills, D., Raybould, H.E. 2017. Prebiotic milk oligosaccharides prevent development of obese phenotype, impairment of gut permeability, and microbial dysbiosis in high fat-fed mice. American Journal of Physiology - Gastrointestinal and Liver Physiology. 312:G474–G487. https://doi.org/10.1152/ajpgi.00427.2016.

A potential tool for clinicians; evaluating a computer-led dietary assessment method in overweight and obese women during weight loss - (Peer Reviewed Journal)
Widaman, A., Keim, N.L., Burnett, D.D., Miller, B., Witbract, M.G., Widaman, K.F., Laugero, K.D. 2017. A potential tool for clinicians; evaluating a computer-led dietary assessment method in overweight and obese women during weight loss. Nutrients. doi: 10.3390:nu9030218.

Insulin induces a shift in lipid and primary carbon metabolites in a model of fasting-induced insulin resistance - (Peer Reviewed Journal)
Olmstead, K.I., Lafrano, M.R., Fahrmann, J., Grapov, D., Viscarra, J.A., Newman, J.W., Oliver, F., Crocker, D.E., Filipp, F.V., Ortiz, R.M. 2017. Insulin induces a shift in lipid and primary carbon metabolites in a model of fasting-induced insulin resistance. Metabolomics. 13:60. doi: 10.1007/s11306-017-1186-y.

The effects of moderate whole grain consumption on fasting glucose and lipids, gastrointestinal symptoms, and microbiota - (Peer Reviewed Journal)
Cooper, D.N., Kable, M.E., Marco, M.L., De Leon, A., Rust, B.M., Baker, J.E., Horn, W.F., Burnett, D., Keim, N.L. 2017. The effects of moderate whole grain consumption on fasting glucose and lipids, gastrointestinal symptoms, and microbiota. Nutrients. 9(2):173. doi: 10.3390/nu9020173.

Metabolic perturbations of postnatal growth restriction and hyperoxia-induced pulmonary hypertension in a bronchopulmonary dysplasia model Reprint Icon - (Peer Reviewed Journal)
La Frano, M.R., Fahrmann, J.F., Grapov, D., Fiehn, O., Pedersen, T.L., Newman, J.W., Underwood, M.A., Steinhorn, R.H., Wedgwood, S. 2017. Metabolic perturbations of postnatal growth restriction and hyperoxia-induced pulmonary hypertension in a bronchopulmonary dysplasia model. Metabolomics. 13:32. https://doi.org/10.1007/s11306-017-1170-6.

Metabolic perturbations of postnatal growth restriction and hyperoxia-induced pulmonary hypertension in a bronchopulmonary dysplasia model - (Peer Reviewed Journal)
La Frano, M.R., Fahrmann, J.F., Grapov, D., Fiehn, O., Pedersen, T.L., Newman, J.W., Underwood, M.A., Steinhorn, R.H., Wedgwood, S. 2017. Metabolic perturbations of postnatal growth restriction and hyperoxia-induced pulmonary hypertension in a bronchopulmonary dysplasia model. Metabolomics. 32:13.

Late-pregnancy salivary cortisol concentrations of Ghanaian women participating in a randomized controlled trial of prenatal lipid-based nutrient supplements Reprint Icon - (Peer Reviewed Journal)
Oakes, B.M., Laugero, K.D., Stewart, C.P., Adu-Afarwuah, S., Lartey, A., Ashorn, P., Vosti, S., Dewey, K.G. 2016. Late-pregnancy salivary cortisol concentrations of Ghanaian women participating in a randomized controlled trial of prenatal lipid-based nutrient supplements. Journal of Nutrition. 146(2):343-352. https://doi.org/10.3945/jn.115.219576.

Sweat lipid mediator profiling: a non-invasive approach for cutaneous research - (Abstract Only)
Agrawal, K., Hassoun, L., Notay, M., Foolad, N., Sivamani, R.K., Newman, J.W. 2016. Inflammatory Mediator Profiling in Sweat: A Potential Noninvasive Diagnostic for Inflammatory Skin Diseases. Meeting Abstract. LIPID MAPS Annual Meeting 2016, May 17-18, 2016, La Jolla, CA.

Estradiol, SHBG and leptin interplay with food craving and intake across the menstrual cycle - (Peer Reviewed Journal)
Krishnan, S., Tyron, R.R., Horn, W.F., Welch, L., Keim, N.L. 2016. Estradiol, SHBG and leptin interplay with food craving and intake across the menstrual cycle. Physiology and Behavior. 165:304-312. doi: 10.1016/j.physbeh.2016.08.010.

Circulating levels of endocannabinoids and oxylipins altered by dietary lipids in older women are likely associated with previously identified gene targets - (Peer Reviewed Journal)
Watkins, B.A., Kim, J., Kenny, A., Pedersen, T.L., Pappan, K.L., Newman, J.W. 2016. Circulating levels of endocannabinoids and oxylipins altered by dietary lipids in older women are likely associated with previously identified gene targets. BBA Molecular and Cell Biology of Lipids. 1861(11). doi: 10.1016/j.bbalip.2016.07.007.

Perinatal triphenyl phosphate exposure accelerates type 2 diabetesonset and increases adipose accumulation in UCD-type 2 diabetesmellitus rats - (Peer Reviewed Journal)
Green, A.J., Graham, J.L., Gonzalez, E.A., Lafrano, M.R., He, G., Pertopoulou, S.E., Park, J., Denison, M., Newman, J.W. 2016. Perinatal exposure to the flame retardant triphenyl phosphate accelerates the onset of type 2 diabetes and causes adipose accumulation in UCD-type 2 diabetes mellitus rats. Reproductive Toxicology. pii: S0890-6238(16)30266-0. doi: 10.1016/j.reprotox.2016.07.009.

Using a lipidomics approach for nutritional phenotyping in response to a test meal containing gamma-linolenic acid - (Peer Reviewed Journal)
Cajka, T., Davis, R., Austin, K.J., Newman, J.W., German, J., Fiehn, O., Smilowitz, J.T. 2016. Using a lipidomics approach for nutritional phenotyping in response to a test meal containing gamma-linolenic acid. Journal of Proteome Research. 12:127. doi: 10.1007/s11306-016-1075-9.

Plasma fatty acids, oxylipins, and risk of myocardial infarction: the Singapore Chinese health study - (Peer Reviewed Journal)
Sun, Y., Koh, H.W., Choi, H., Koh, W., Yuan, J., Newman, J.W., Su, J., Fang, J., Ong, C., Van Dam, R.M. 2016. Plasma fatty acids, oxylipins, and risk of myocardial infarction: the Singapore Chinese health study. Journal of Lipid Research. 57:1300-1307.

Association between plasma endocannabinoids and appetite in hemodialysis patients: a pilot study - (Peer Reviewed Journal)
Freidman, A.N., Kim, J., Kaiser, S., Pedersen, T., Newman, J.W., Watkins, B.A. 2016. Association between plasma endocannabinoids and appetite in hemodialysis patients: a pilot study. American Journal of Kidney Diseases. 36(7):658-662. doi: 10.1016/j.nutres.2016.03.009.

A randomized placebo controlled trial of ibuprofen for respiratory syncytial infection in a bovine model study - (Peer Reviewed Journal)
Walsh, P., Behrens, N., Crvallo Chaigneau, F.R., Mcelligot, H., Agrawal, K., Newman, J.W., Andersen, M., Gershwin, L.J. 2016. A randomized placebo controlled trial of ibuprofen for respiratory syncytial infection in a bovine model study. PLoS One. 11(4):e0152913. doi: 10.1371/journal.pone.0152913.

The value of anthropometric indices for identifying women with features of metabolic syndrome - (Abstract Only)
Welch, L.C., Horn, W.F., Krishnan, S., Kishimura, K.M., Que, E.S., Holguin, E., Keim, N.L. 2016. The value of anthropometric indices for identifying women with features of metabolic syndrome. Meeting Abstract. Experimental Biology 2016, San Diego, CA, April 2-6, 2016..

The genetic architecture of coronary artery disease: current knowledge and future opportunities - (Review Article)
Hartiala, J., Schwartzman, W.S., Gabbay, J., Ghazalpour, A., Bennett, B.J., Allayee, H. 2017. The genetic architecture of coronary artery disease: current knowledge and future opportunities. Current Atherosclerosis Reports. 19(2):6. doi: 10.1007/s11883-017-0641-6.

Maternal cortisol and stress are associated with birth outcomes, but are not affected by lipid-based micronutrient supplements during pregnancy: an analysis of data from a randomized controlled trial in rural Malawi - (Peer Reviewed Journal)
Stewart, C.P., Oakes, B.M., Laugero, K.D., Ashorn, U., Harjunmaa, U., Kumwenda, C., Chaima, D., Maleta, K., Ashorn, P., Dewey, K.G. 2015. Maternal cortisol and stress are associated with birth outcomes, but are not affected by lipid-based micronutrient supplements during pregnancy: an analysis of data from a randomized controlled trial in rural Malawi. BMC Pregnancy & Childbirth. 15:346. doi: 10.1186/s12884-015-0793-8.

Bile Acid Responses in Methane and Non-Methane Producers to Standard Breakfast Meals - (Abstract Only)
Rust, B., La Frano, M., Newman, J.W., Agrawal, K., Horn, W.F., Welch, L., Marco, M., Martin, R., Keim, N.L. 2016. Bile Acid Responses in Methane and Non-Methane Producers to Standard Breakfast Meals. Meeting Abstract. Experimental Biology 2016, San Diego, CA April 2-6, 2016.

Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice - (Peer Reviewed Journal)
Midtbø, L.K., Borkowska, A.G., Bernhard, A., Rønnevik, A.K., Lock, E., Fitzgerald, M.L., Torstensen, B.E., Liaset, B., Brattelid, T., Pedersen, T.L., Newman, J.W., Kristiansen, K., Madsen, L. 2015. Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice. Journal of Nutritional Biochemistry. 26(6):585-595. doi: 10.1016/j.jnutbio.2014.12.005.

The elusive endogenous adipogenic PPARy agonists: lining up the suspects - (Review Article)
Hallenborg, P., Petersen, R.K., Newman, J.W., Madsen, L., Kristiansen, K. 2015. The elusive endogenous adipogenic PPARy agonists: lining up the suspects. Cell Metabolism. 61:149-162. doi: 10.1016/j.plipres.2015.11.002.

Comparison of the Effects of a Sweetened Beverage Intervention on Self-Selected Food Intake - (Abstract Only)
Widaman, A.M., Stanhope, K.L., Chen, G.X., Medici, V., Bremer, A.A., Lee, V., Nunez, M.V., Havel, P.J., Keim, N.L. 2016. Comparison of the Effects of a Sweetened Beverage Intervention on Self-Selected Food Intake. Meeting Abstract. Experimental Biology 2016, April 2-6, 2016, San Diego, CA.

Dietary Adherence Monitoring Tool for Free-living, Controlled Feeding Studies - (Abstract Only)
Burnett, D.J., Peerson, J.M., Miller, B., Welch, L.C., Witbract, M.G., Krishnan, S., Keim, N.L. 2016. Dietary Adherence Monitoring Tool for Free-living, Controlled Feeding Studies. Meeting Abstract. Experimental Biology 2016, San Diego, CA April 2-6, 2016.

Menstrual cycle hormones, food intake, and cravings - (Abstract Only)
Krishnan, S., Tyron, R., Welch, L., Horn, W.F., Keim, N.L. 2016. Menstrual cycle hormones, food intake, and cravings. Meeting Abstract. Experimental Biology 2016, April 2-6, 2016, San Diego, CA.

Relationship between Human Gut Microbiota and Interleukin 6 Levels in Overweight and Obese Adults - (Abstract Only)
Cooper, D., Kim, E., Marco, M., Rust, B., Welch, L., Horn, W.F., Freytag, T.L., Martin, R., Keim, N.L. 2016. Relationship between Human Gut Microbiota and Interleukin 6 Levels in Overweight and Obese Adults. Meeting Abstract. Experimental Biology 2016, April 2-6, 2016, San Diego, CA..

Effects of Extra Virgin Olive Oil (EVOO) Oleocanthal and Oleacein Content on Platelet Reactivity in Healthy Adults - (Abstract Only)
Holt, R.R., Agarwal, K., Li, X., Melliou, E., Pedersen, T., Wang, S., Flynn, D., Magiatis, P., Newman, J.W. 2016. Effects of Extra Virgin Olive Oil (EVOO) Oleocanthal and Oleacein Content on Platelet Reactivity in Healthy Adults. Meeting Abstract. Experimental Biology 2016, San Diego CA Apr. 2-6.

Vitamin B-12 treatment of asymptomatic, deficient, elderly Chileans improves conductivity in myelinated periphreal nerves, but high serum folate impairs vitamin B-12 status response assessed by the combined indicator of.. - (Peer Reviewed Journal)
Brito, A., Miller, J.W., Green, R., Fedosov, S.N., Harvey, D., Shahab-Ferdows, S., Verdugo, R., Sanchez, H., Albala, C., Uauay, R., Allen, L.H. 2016. Vitamin B-12 treatment of asymptomatic, deficient, elderly Chileans improves conductivity in myelinated periphreal nerves, but high serum folate impairs vitamin B-12 status response assessed by the combined indicator of vitamin B-12 status. American Journal of Clinical Nutrition. 103:250-257. doi: 10.3945/ajcn.115.116509.

The impact of micronutrient supplementation in alcohol-exposed pregnancies on information processing skills in Ukrainian infants - (Peer Reviewed Journal)

Dietary DHA reduced downstream endocannabinoid and inflammatory gene expression, epididymal fat mass, and improved aspects of glucose use in muscle in C57BL/6J mice - (Peer Reviewed Journal)
Kim, J., Carlson, M.E., Kuchel, G.A., Newman, J.W., Watkins, B.A. 2015. Dietary DHA reduced downstream endocannabinoid and inflammatory gene expression, epididymal fat mass, and improved aspects of glucose use in muscle in C57BL/6J mice. International Journal of Obesity. 40:129–37; doi: 10.1038/ijo.2015.135.

Does whole grain consumption alter gut microbiota and satiety? - (Peer Reviewed Journal)
Cooper, D.N., Martin, R.J., Keim, N.L. 2015. Does whole grain consumption alter gut microbiota and satiety? Healthcare. 3(2)364-392. doi: 10.3390/healthcare3020364.

Mutations in durum wheat SBEII genes conferring increased amylose and resistant starch affect grain yield components, semolina and pasta quality and fermentation responses in rats - (Peer Reviewed Journal)
Hazard, B., Zhang, X., Naemeh, R., Hamilton, K.M., Rust, B., Raybould, H.E., Newman, J.W., Martin, R., Dubcovsky, J. 2015. Mutations in durum wheat SBEII genes conferring increased amylose and resistant starch affect grain yield components, semolina and pasta quality and fermentation responses in rats. Crop Science. 55(6):2813–2825. doi: 10.2135/cropsci2015.03.0179.

Molecular dynamic simulations reveal the structural determinants of fatty acid binding to oxy-myoglobin - (Peer Reviewed Journal)
Chintapalli, S.V., Bhardwaj, G., Patel, R., Shah, N., Anishkin, A., Von Rossum, D.B., Patterson, R.L., Adams, S.H. 2015. Molecular dynamic simulations reveal the structural determinants of fatty acid binding to oxy-myoglobin. PLoS One. 10(6):e0128496. doi: 10.1371/journal.pone.0128496.

Long-chain acylcarnitines activate cell stress and myokine release in C2C12 myotubes: calcium-dependent and independent effects Reprint Icon - (Peer Reviewed Journal)
McCoin, C.S., Knotts, T.A., Ono-Moore, K.D., Oort, P.J., Adams, S.H. 2015. Long-chain acylcarnitines activate cell stress and myokine release in C2C12 myotubes: calcium-dependent and independent effects. American Journal of Physiology. 308 (11): E990-E1000. DOI: 10.1152/ajpendo.00602.2014.

Excessive sugar consumption may be a difficult habit to break: a view from the brain and body Reprint Icon - (Peer Reviewed Journal)
Tryon, M.S., Stanhope, K.L., Epel, E.S., Mason, A.E., Brown, R., Medici, V., Havel, P.J., Laugero, K.D. 2015. Excessive sugar consumption may be a difficult habit to break: a view from the brain and body. Journal of Clinical Endocrinology and Metabolism. 100(6):2239-2247. https://doi.org/10.1210/jc.2014-4353.

A dose-response of consuming high fructose corn syrup-sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults - (Peer Reviewed Journal)
Stanhope, K.L., Medici, V., Bremer, A.A., Lee, V., Lam, H.D., Nunez, M.V., Chen, G.X., Keim, N.L., Havel, P.J. 2015. A dose-response of consuming high fructose corn syrup-sweetened beverages on lipid/lipoprotein risk factors for cardiovascular disease in young adults. American Journal of Clinical Nutrition. 101(6):1144-1154. doi: 10.3945/ajcn.114.100461.

Acute treatment with XMetA activates hepatic insulin receptors and lowers blood glucose in normal mice - (Peer Reviewed Journal)
Bedinger, D.H., Kieffer, D.A., Goldfine, I.D., Roell, M.K., Adams, S.H. 2015. Acute treatment with XMetA activates hepatic insulin receptors and lowers blood glucose in normal mice. Journal of Cellular Biochemistry. 116(9):2109-2119. doi: 10.1002/jcb.25168.

Identifying nutrients that are under-reported by an automated 24-hour dietary recall method in overweight and obese women after weight loss - (Abstract Only)
Widaman, A.M., Burnett, D.J., Miller, B., Witbract, M., Keim, N.L., Laugero, K.D. 2015. Identifying nutrients that are under-reported by an automated 24-hour dietary recall method in overweight and obese women after weight loss. Meeting Abstract. 2015 Academy of Nutrition & Dietetics Annual Meeting , Nashville TN, October 3-6, 2015.

A novel approach to identify optimal metabotypes of elongase and desaturase activities in prevention of acute coronary syndrome Reprint Icon - (Peer Reviewed Journal)
Tintle, N.L., Newman, J.W., Shearer, G.C. 2015. A novel approach to identify optimal metabotypes of elongase and desaturase activities in prevention of acute coronary syndrome. Metabolomics. 11(1):1-11. doi: 10.1007/s11306-015-0787-6.

Fructose and high fructose corn syrup - (Book / Chapter)
Keim, N.L., Stanhope, K.L., Havel, P.J. 2016. Fructose and high fructose corn syrup. In: Caballero, B., editor. Encyclopedia of Food and Health. Academic Press. p. 119-124.

Differential pathway coupling efficiency of the activated insulin receptor drives signaling selectivity by XMetA, an allosteric partial agonist antibody - (Peer Reviewed Journal)
Bedinger, D.H., Goldfine, I.D., Corbin, J.A., Roell, M.K., Adams, S.H. 2015. Differential pathway coupling efficiency of the activated insulin receptor drives signaling selectivity by XMetA, an allosteric partial agonist antibody. Journal of Pharmacology and Experimental Therapeutics. 353(1):35-43. doi: 10.1124/jpet.114.221309.

Short chain fatty acid production and glucose responses by methane producers - (Abstract Only)
Rust, B., Gray, I.J., Keifer, D., Newman, J.W., Cooper, D., Welch, L., Horn, W.F., Marco, M., Pelkman, C., Keim, N.L. 2014. Short chain fatty acid production and glucose responses by methane producers. Meeting Abstract. Experimental Biology Meeting, Boston MA, March 28-April 1, 2015.

Does mere exposure mediate sensitivity to bitter taste on consumer liking and acceptability of whole grain foods? - (Abstract Only)
De Leon, A., Giovanni, M., Horn, W.F., Burnett, D., Keim, N.L. 2015. Does mere exposure mediate sensitivity to bitter taste on consumer liking and acceptability of whole grain foods?. Meeting Abstract. Experimental Biology 2015, Boston, MA March 28 – April 1, 2015.

A resistant starch fiber diet ameliorates oxidative stress, inflammation, and progression of chronic kidney disease (CKD) - (Peer Reviewed Journal)

Breakfast skippers display a disrupted cortisol rhythm and elevated blood pressure - (Peer Reviewed Journal)
Whitbracht, M.G., Keim, N.L., Forester, S., Widaman, A., Laugero, K.D. 2015. Breakfast skippers display a disrupted cortisol rhythm and elevated blood pressure. Physiology and Behavior. 140:215-221. doi:10.1016/j.physbeh.2014.12.044.

Association Between Barriers and Facilitators to Meeting the Dietary Guidelines for Americans and Body Weight Status: The HEALTH Study - (Peer Reviewed Journal)

Whey protein supplementation does not alter plasma branched-chained amino acid profiles but results in unique metabolomics patterns in obese women enrolled in an 8-week weight loss trial - (Peer Reviewed Journal)
Piccolo, B.D., Comerford, K.B., Karakas, S.E., Knotts, T.A., Fiehn, O., Adams, S.H. 2015. Whey protein supplementation does not alter plasma branched-chained amino acid profiles but results in unique metabolomics patterns in obese women enrolled in an 8-week weight loss trial. Journal of Nutrition. 145(4):691-700. doi: 10.3945/jn.114.203943.

Chronic stress is associated with indicators of diet quality in habitual breakfast skippers - (Peer Reviewed Journal)
Widaman, A.M., Witbracht, M.G., Forester, S.M., Laugero, K.D., Keim, N.L. 2016. Chronic stress is associated with indicators of diet quality in habitual breakfast skippers. Journal of the Academy of Nutrition and Dietetics. 116(11):1776-1784. doi: 10.1016/j.jand.2016.03.016.

High amylose resistant starch diet ameliorates oxidative stress, inflammation, and progression of chronic kidney disease (CKD) - (Abstract Only)
Liu, S., Nazer-Tehrani, S., Farzaneh, S.H., Lau, W.L., Khazaeli, M., Adams, S.H., Kieffer, D.A., Martin, R., Vaziri, N.D. 2014. High amylose resistant starch diet ameliorates oxidative stress, inflammation, and progression of chronic kidney disease (CKD). PLoS One. 9(12):e114881. DOI: 10.1371/journal.pone.0114881.

Branched-chain amino acids in metabolic signaling and insulin resistance - (Peer Reviewed Journal)
Lynch, C.J., Adams, S.H. 2014. Branched-chain amino acids in metabolic signaling and insulin resistance. Nature Reviews Endocrinology. 10(12):723-736. doi: 10.1038/nrendo.2014.171.

Temporal metabolomic responses of cultured HepG2 liver cells to high fructose and high glucose exposures - (Peer Reviewed Journal)
Meissen, J.K., Hirahatake, K.M., Adams, S.H., Fiehn, O. 2014. Temporal metabolomic responses of cultured HepG2 liver cells to high fructose and high glucose exposures . Metabolomics. 11(3):707-721, DOI:10.1007/S11306-014-0729-8.

Dietary whole grain-microbiota interactions: insights into mechanisms for human health - (Peer Reviewed Journal)
Keim, N.L., Martin, R.J. 2015. Dietary whole grain-microbiota interactions: insights into mechanisms for human health. Advances in Nutrition. 5:556–557. doi: 10.3945/an.114.006536.

Perinatal exposure to the pesticide DDT impairs energy expenditure and metabolism in adult female mice - (Peer Reviewed Journal)
La Merrill, M., Karey, E., Moshier, E., Lindtner, C., La Frano, M., Newman, J.W., Buettner, C. 2014. Perinatal exposure to the pesticide DDT impairs energy expenditure and metabolism in adult female mice. PLoS One. 9(7):e103337. doi: 10.1371/journal.pone.0103337.

High dose simvastatin exhibits enhanced lipid lowering effects relative to simvastatin/ezetimibe combination therapy - (Peer Reviewed Journal)
Snowden, S.G., Grapov, D., Nygren, H., Settergren, M., D'Alexandri, F.L., Haeggstrom, J.Z., Hyotylainen, T., Oresic, M., Pedersen, T.L., Newman, J.W., Pernow, J., Wheelock, C.E. 2014. High dose simvastatin exhibits enhanced lipid lowering effects relative to simvastatin/ezetimibe combination therapy. Circulation: Cardiovascular Genetics. 7:955-964. doi: 10.1161/CIRCGENETICS.114.000606.

Impact of a UCP3 Loss-of-Function Polymorphism on the Plasma Metabolomic Profile in Obese African-American Women - (Peer Reviewed Journal)
Piccolo, B.D., Grapov, D., Adams, S.H., Hoppel, C., Garvey, W., Fiehn, O., Harper, M., Newman, J.W. 2010. Impact of a UCP3 Loss-of-Function Polymorphism on the Plasma Metabolomic Profile in Obese African-American Women. Journal of Federation of American Societies for Experimental Biology. https://doi.org/10.1371/journal.pone.0015234.s002.