Research Project: Vision, Aging, and Nutrition

Location: Jean Mayer Human Nutrition Research Center On Aging

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Too sweet: problems of protein glycation in the eye - (Review Article)
Bejarano, E., Taylor, A. 2018. Too sweet: problems of protein glycation in the eye. Experimental Eye Research. 178:255-262. https://doi.org/10.1016/j.exer.2018.08.017.

Stabilization of p27Kip1/CDKN1B by UBCH7/UBE2L3 catalyzed ubiquitinylation: a new paradigm in cell-cycle control - (Peer Reviewed Journal)
Whitcomb, E., Tsai, Y., Basappa, J., Liu, K., Le Feuvre, A., Weissman, A.M., Taylor, A. 2018. Stabilization of p27Kip1/CDKN1B by UBCH7/UBE2L3 catalyzed ubiquitinylation: a new paradigm in cell-cycle control. Journal of Federation of American Societies for Experimental Biology. https://doi.org/10.1096/fj.201800960R.

Studies of advanced glycation end products and oxidation biomarkers for type 2 diabetes - (Peer Reviewed Journal)
Chiu, C., Rabbani, N., Rowan, S., Chang, M., Sawyer, S., Hu, F.B., Willett, W.C., Thornalley, P., Anwar, A., Bar, L., Kang, J.H., Taylor, A. 2018. Studies of advanced glycation end products and oxidation biomarkers for type 2 diabetes. Biofactors. https://doi.org/10.1002/biof.1423.

The role of microbiota in retinal disease - (Review Article)
Rowan, S., Taylor, A. 2018. The role of microbiota in retinal disease. Advances in Experimental Medicine and Biology. p. 429-435. https://doi.org/10.1007/978-3-319-75402-4_53.

Gut microbiota modify risk for dietary glycemia-induced age-related macular degeneration - (Other)
Rowan, S., Taylor, A. 2018. Gut microbiota modify risk for dietary glycemia-induced age-related macular degeneration. Gut Microbes. 21:1-6. https://doi.org/10.1080/19490976.2018.1435247.

Glycemically stressed Nrf2-null mice develop features of age-related macular degeneration and diabetic retinopathy - (Abstract Only)
Rowan, S., Jiang, S., Moreira-Neto, C., Chang, M., Smith, D.E., Waheed, N.K., Taylor, A. 2018. Glycemically stressed Nrf2-null mice develop features of age-related macular degeneration and diabetic retinopathy [abstract]. Investigative Ophthalmology and Visual Science. 59(9) Abstract No. 2440.

Diet, metabolomics, microbiome, and proteolytic processes related to retinal diseases - (Abstract Only)
Taylor, A. 2018. Diet, metabolomics, microbiome, and proteolytic processes related to retinal diseases [abstract]. Association for Research in Vision and Ophthalmology 2018. 59(9):2974.

Involvement of a gut-retina axis in protection against dietary glycemia induced age-related macular degeneration - (Peer Reviewed Journal)
Rowan, S., Jiang, S., Korem, T., Szymanski, J., Chang, M., Szelog, J., Cassalman, C., Dasuri, K., Mcguire, C., Nagai, R., Du, X., Brownlee, M., Rabbani, N., Thornalley, P.J., Baleja, J.D., Deik, A., Pierce, K.A., Scott, J.M., Clish, C.B., Smith, D.E., Weinberger, A., Avnit-Sagi, T., Lotan-Pompan, M., Segal, E., Taylor, A. 2017. Involvement of a gut-retina axis in protection against dietary glycemia induced age-related macular degeneration. Proceedings of the National Academy of Sciences. 114(22):E4472-E4481. https://doi.org/10.1073/pnas.1702302114.

Visualization of dietary patterns and their associations with age-related macular degeneration - (Peer Reviewed Journal)
Chiu, C., Chang, M., Li, T., Gensler, G., Taylor, A. 2017. Visualization of dietary patterns and their associations with age-related macular degeneration. Investigative Ophthalmology and Visual Science. doi: 10.1167/iovs.16-20454.

Contribution of the Nurses' Health Study to the epidemiology of cataract, age-related macular degeneration, and glaucoma - (Peer Reviewed Journal)
Kang, J.H., Wu, J., Cho, E., Ogata, S., Jacques, P.F., Taylor, A., Chiu, C., Wiggs, J.L., Seddon, J.M., Hankinson, S.E., Schaumberg, D.A., Pasquale, L.R. 2016. Contribution of the Nurses' Health Study to the epidemiology of cataract, age-related macular degeneration, and glaucoma. American Journal of Public Health. 106(9):1684-1689. https://doi.org/10.2105/AJPH.2016.303317.

Disassembly of the lens fiber cell nucleus to create a clear lens: the p27 descent - (Review Article)
Rowan, S., Chang, M., Reznikov, N., Taylor, A. 2016. Disassembly of the lens fiber cell nucleus to create a clear lens: the p27 descent. Experimental Eye Research. 156:72-78. doi: 10.1016/j.exer.2016.02.011.

Unfolded-protein response-associated stabilization of p27(Cdkn1b) interferes with lens fiber cell denucleation, leading to cataract - (Peer Reviewed Journal)
Lei, L., Whitcomb, E., Jiang, S., Chang, M., Gu, Y., Duncan, M.K., Cvekl, A., Want, W., Limi, S., Reneker, L.W., Shang, F., Du, L., Taylor, A. 2016. Unfolded-protein response-associated stabilization of p27(Cdkn1b) interferes with lens fiber cell denucleation, leading to cataract. Journal of Federation of American Societies for Experimental Biology. 30(3):1087-1095. doi: 10.1096/fj.15-278036.

Gene-diet interactions in age-related macular degeneration - (Book / Chapter)
Rowan, S., Taylor, A. 2015. Gene-diet interactions in age-related macular degeneration. In: Bowes Rickman, C., editor. Advances in Experimental Medicine and Biology: Reginal Degenerative Diseases. Switzerland: Springer International. p.95-101. doi: 10.1007/978-3-319-17121-0_14

Dietary glycemia as a determinant of health and longevity - (Review Article)
Whitcomb, E.A., Chiu, C., Taylor, A. 2015. Dietary glycemia as a determinant of health and longevity. Molecular Aspects of Medicine. 46:14-20. http://dx.doi.org/10.1016/j.mam.2015.08.005.

Altered ubiquitin causes perturbed calcium homeostasis, hyperactivation of calpain, dysregulated differentiation, and cataract - (Peer Reviewed Journal)
Liu, K., Lyu, L., Chin, D., Gao, J., Sun, X., Shang, F., Caceres, A., Chang, M., Rowan, S., Peng, J., Mathias, R., Kasahara, H., Jiang, S., Taylor, A. 2015. Altered ubiquitin causes perturbed calcium homeostasis, hyperactivation of calpain, dysregulated differentiation, and cataract. Proceedings of the National Academy of Sciences. 112(4):1071-1076. https://doi.org/10.1073/pnas.1404059112.