Location: Avian Disease and Oncology Research
Project Number: 5050-31320-009-13-A
Project Type: General Cooperative Agreement
Start Date: Sep 15, 2013
End Date: Sep 14, 2014
1) Improve the chicken genome sequence assembly, and 2) Enhance genetic resistance to Marek's disease in chicken.
To improve the chicken genome, we will (1) provide Red Jungle Fowl DNA to Washington School of Medicine at St. Louis for sequencing (PacBio, Moleculo, etc.) and (2) based on the information, develop genetic maps, especially for regions that are deficieint in genetic markers. To enhance genetic resistance to Marek's disease, we will use allele-specific expression in response to Marek's disease virus challenge to identify SNPs that will be used to genotype resource populations.