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United States Department of Agriculture

Agricultural Research Service

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Research Project: Assessing Accuracy of Intra-Family Genome Breeding Values Using Restriction-Site Associated DNA (RAD) SNPs in Rainbow Trout

Location: Cool and Cold Water Aquaculture Research

Project Number: 8082-31000-012-02-S
Project Type: Non-Assistance Cooperative Agreement

Start Date: May 1, 2013
End Date: Sep 30, 2016

To evaluate the potential of intra-family genomic selection for bacterial cold water disease (BCWD) resistance in rainbow trout using RAD (Restriction-site associated DNA) SNP (single nucleotide polymorphism) genotyping of historic samples from the NCCCWA 2005 and 2007 brood year families that were previously phenotyped for BCWD resistance.

We will use RAD SNPs to genotype the 2005 brood-year parents and phenotyped offspring from eight families and their siblings that were used as breeders in 2007, which will allow us to generate genomic estimated breeding values (GEBV) for the 2007 breeders. We will then compare the GEBV ranking of the breeders within each family to the ranking based on the actual performance from progeny testing that was done in 2007 and will calculate correlations for each family (i.e. accuracy of GEBV). High correlations will indicate that the intra-family genomic selection can improve the efficiency of selection for BCWD resistance in rainbow trout, and through simulations we will be able to calculate predicted genetic gain from using predicted animal’s GEBV to select breeders rather than randomly selecting breeders from the top performing families.

Last Modified: 10/17/2017
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