Project Number: 8042-21220-251-07-S
Project Type: Non-Assistance Cooperative Agreement
Start Date: Sep 18, 2012
End Date: Sep 30, 2016
The objectives are to develop mutants of Streptomyces that are deficient in expression of three family-12 endoglucanases. Develop mutants of additional pathogenicity-related genes and to train scientists in Streptomyces mutagenesis.
Individual genes or gene fragments will be cloned and transferred to appropriate vectors for use in mutagenesis experiments. Tests will be conducted to determine the effect of mutagenesis on development of Streptomyces-induced common scab disease.