1a. Objectives (from AD-416):
Potatoes are widely used throughout the world as a staple food. Recently, their role in the diet has been questioned, particularly in relation to glycemia and the risk of developing type 2 diabetes mellitus. We challenge that notion, and propose that consuming potatoes as part of a mixed meal can be a healthy adjunct to lifestyle modification for reducing risk markers of cardiometabolic disease. In order to test this hypothesis, we will carry out a controlled feeding trial with overweight/obese volunteers in which we will compare potatoes containing high or low amounts of resistant starch to other commonly consumed carbohydrate sources in a lifestyle modification program. We will assess the effects of those treatments on biomarkers of cardiometabolic risk: blood glucose responses, insulin sensitivity, lipids and inflammatory markers. These studies will be carried out at the USDA Grand Forks Human Nutrition Research Center (GFHNRC).
1b. Approach (from AD-416):
Our primary objective is to compare the cardiometabolic effects of potato consumption to those of commonly consumed carbohydrate sources on glucose tolerance in overweight and obese, glucose intolerant men and women participating in a lifestyle intervention program. We hypothesize that consumption of potatoes is a healthy adjunct to lifestyle intervention in overweight and obese glucose intolerant adults. Our specific aims include: (1) to evaluate of the effects of the consumption of potatoes (high or low resistant starch) vs. commonly consumed carbohydrate sources on glucose tolerance; and (2) to determine the extent to which potato consumption alters markers of lipid metabolism and inflammation in the context of a lifestyle intervention program.
3. Progress Report:
Advertisements were placed in the Dakota Student, UND Newsletter, Grand Forks Herald, and Around the Forks Newsletter. We are trying to place ads in the Grand Forks Air Force Base newsletter. Flyers were printed and dispersed to retail outlets in the area. We also featured the study at the health fair held at the Alerus Center. We also explored television and internet advertisements. 65 individuals completed the online application. Of those, 9 subjects completed the study in the first group, 9 subjects are currently in the second group, 2 people didn’t show for their information meeting, 14 declined to participate, 4 did not reply, 7 had a BMI > 39.9, 1 had a blood glucose > 125 mg/dl, 3 were disqualified due to medications, 1 person was disqualified due to surgery, 1 person was disqualified due to a medical issue, 2 dropped out after starting the meals, 8 are on the list for the next group and 4 are doing other studies. ARS PI monitoring activities to evaluate research progress included: phone calls/ conference calls, email communications, discussions at professional conferences/ meetings, and review of Accomplishment Report.