Project Number: 5030-32000-106-11-N
Project Type: Nonfunded Cooperative Agreement
Start Date: Feb 1, 2012
End Date: Jan 31, 2013
Determine if there is a correlation between bovine viral diarrhea virus (BVDV) neutralizing antibodies and protection against BVDV exposure in vaccinated calves.
Angus beef calves raised under production conditions will be vaccinated with a commercial bovine viral diarrhea virus (BVDV) vaccine. Calves with low, mid range, or high levels of serum neutralizing antibodies following vaccination will be selected. Selected calves will be transferred to the National Animal Disease Center and challenged with a high virulence BVDV. This will be done to determine the level of neutralizing antibodies required for protection.