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United States Department of Agriculture

Agricultural Research Service

Related Topics

Research Project: A NOVEL MULTIVALENT VECTORED VACCINE AGAINST BVDV

Location: Ruminant Diseases and Immunology Research

Project Number: 5030-32000-106-08-T
Project Type: Trust

Start Date: Oct 6, 2011
End Date: Dec 31, 2013

Objective:
The purpose of this collaboration is to construct and test an alphavirus replicon particle vaccine that expresses the E2 regions of three different BVDV strains, one being a BVDV1a, one a BVDV1b, and one a BVDV2a.

Approach:
Construct an alphavirus replicon particle vaccine that expresses the E2 regions of three different BVDV strains, one being a BVDV1a, one a BVDV1b, and one a BVDV2a. This prototype vaccine would be administered to BVDV naïve calves and the immune response evaluated.

Last Modified: 2/23/2016
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