1a. Objectives (from AD-416):
The objective of this cooperative research project is to jointly study avian influenza viruses, paramyxoviruses, pneumoviruses and other viral agents of poultry that potential can cross between birds and humans.
1b. Approach (from AD-416):
The studies will use immunological, virological, molecular, genetic, and pathological methodologies and animal models to study the pathogenesis, immunology, vaccine safety and efficacy, therapeutics and epidemiology of the viruses and infections they cause.
3. Progress Report:
This research is directly related to inhouse objective 3 -Identify genetic and biological determinants of avian influenza virus susceptibility and resistance in avian species and inhouse project 4 - Improve existing diagnostic tests and testing strategies for avian influenza virus surveillance, detection, and recovery from disease outbreaks. During FY2013, ARS provided the cooperator with one H7N9 avian influenza virus from China, two reassortant H5 and H7 vaccine viruses, and three H5N1 highly pathogenic avian influenza viruses (two from Vietnam and one from Egypt) to be used in vaccine studies.