Project Number: 2030-42000-048-06-R
Project Type: Reimbursable
Start Date: Mar 1, 2010
End Date: Dec 31, 2014
To develop a panel of monoclonal antibodies that will be used to develop sensitive immunoassays for detection of multiple serotypes of botulinum neurotoxin.
Monoclonal anti-toxin antibodies for serotypes B and E will be developed using chemical cell fusion methods following immunization with toxoids, toxins, or recombinant peptides. In addition, antibodies to nontoxin associated proteins will be developed. The monoclonal antibodies will be supplied to DHS contractors and other collaborating federal laboratories in order to format sensitive immunoassays for toxin identification. Documents Reimbursable with U.S Department of Homeland Security. Log 40768. Formerly 5325-42000-043-06R (4/11).