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ARS Home » Southeast Area » Oxford, Mississippi » Natural Products Utilization Research » Research » Research Project #418914

Research Project: Mode of Action of Antidiabetic Activity, Identification of Bioactive Compound and Micropropagation of Serviceberry (Amelanchier Alnifolia)

Location: Natural Products Utilization Research

2011 Annual Report

1a. Objectives (from AD-416)
1. Identify mechanisms that mediate anti-diabetic effects of serviceberry extracts. 2. Isolate and identify the anti-diabetic constituent(s) from serviceberry. 3. Develop a robust micropropagation system for rapid germplasm multiplication, maintenance and storage. 4. Develop efficient organic production systems for serviceberry cultivation.

1b. Approach (from AD-416)
ARS contact scientist will identify anti-diabetic constituents from serviceberry through activity-guided fractionation using an assay that will be conducted at Auburn University, another collaborator in this project. ARS scientist will use various spectroscopic methods to identify the anti-diabetic constituent(s).

3. Progress Report
Serviceberry leaves have been extracted and fractionated following bioassay-guided fractionation. Subfractions have been tested for anti-diabetic activity. An active sub-fraction has been obtained. Isolation of the active anti-diabetic compound is currently being performed. Information concerning this research was monitored through emails and teleconferences.

4. Accomplishments