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United States Department of Agriculture

Agricultural Research Service

Kevin Welch
Res Toxclgst


Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Serum toxicokinetics after intravenous and oral dosing of larkspur toxins in goats - (Peer Reviewed Journal)
Welch, K.D., Gardner, D.R., Stonecipher, C.A., Green, B.T., Pfister, J.A. 2017. Serum toxicokinetics after intravenous and oral dosing of larkspur toxins in goats. Toxicon. 133:91-94. doi: 10.1016/j.toxicon.2017.05.008.
Anagyrine desensitization of peripheral nicotinic acetylcholine receptors. A potential biomarker of quinolizidine alkaloid teratogenesis in cattle. - (Peer Reviewed Journal)
Green, B.T., Lee, S.T., Welch, K.D., Cook, D. 2017. Anagyrine desensitization of peripheral nicotinic acetylcholine receptors. A potential biomarker of quinolizidine alkaloid teratogenesis in cattle.. Research in Veterinary Science. 115:195-200. doi: 10.1016/j.rvsc.2017.04.019.
Changes in the rumen bacterial microbiome of cattle exposed to ponderosa pine needles - (Peer Reviewed Journal)
Welch, K.D., Stonecipher, C.A., Gardner, D.R., Cook, D., Pfister, J.A. 2017. Changes in the rumen bacterial microbiome of cattle exposed to ponderosa pine needles. Journal of Animal Science. 95:2314–2322. doi: 10.2527/jas2016.1228.
Administering multiple doses of a non N-(methylsuccinimido) anthranoyllycoctonine (MSAL)-containing tall larkspur (Delphinium occidentale) to cattle - (Peer Reviewed Journal)
Welch, K.D., Stonecipher, C.A., Green, B.T., Gardner, D.R., Cook, D., Pfister, J.A. 2017. Administering multiple doses of a non N-(methylsuccinimido) anthranoyllycoctonine (MSAL)-containing tall larkspur (Delphinium occidentale) to cattle. Toxicon. 128:46-49. doi: 10.1016/j.toxicon.2017.01.020.
A survey of swainsonine content in Swainsona species - (Peer Reviewed Journal)
Cook, D., Gardner, D.R., Welch, K.D., Allen, J.G. 2017. A survey of swainsonine content in Swainsona species. The Australian Rangeland Journal. 39:213-218. doi: 10.1071/RJ16088.
USDA-ARS Poisonous Plant Research Laboratory: History and current research on western North American rangelands - (Peer Reviewed Journal)
Pfister, J.A., Cook, D., Panter, K.E., Welch, K.D., James, L.F. 2016. USDA-ARS Poisonous Plant Research Laboratory: History and current research on western North American rangelands. Rangelands. 38(5):241-249.
Natural toxins of plant origin (phytotoxins) - ()
Welch, K.D., Lee, S.T., Cook, D., Green, B.T., Panter, K.E. 2017. Natural toxins of plant origin (phytotoxins). In: Witczak, A., Sikorski, Z.E., editors. Toxins and other harmful compounds in foods (chemical & functional properties of food components series). 1st edition. Boca Raton, FL: CRC Press. p. 7-52.
Comparison of the serum toxicokinetics of larkspur toxins in cattle, sheep and goats Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Gardner, D.R., Green, B.T., Stonecipher, C.A., Cook, D., Pfister, J.A. 2016. Comparison of the serum toxicokinetics of larkspur toxins in cattle, sheep and goats. Toxicon. 119:270-273.
Activation and desensitization of peripheral muscle and neuronal nicotinic acetylcholine receptors by selected, naturally-occurring pyridine alkaloids Reprint Icon - (Peer Reviewed Journal)
Green, B.T., Lee, S.T., Welch, K.D., Cook, D., Kem, W.R. 2016. Activation and desensitization of peripheral muscle and neuronal nicotinic acetylcholine receptors by selected, naturally-occurring pyridine alkaloids. Toxins. doi: 10.1016/j.toxicon.2015.09.015.
Impacts of toxic plants on the welfare of grazing livestock - ()
Pfister, J.A., Green, B.T., Welch, K.D., Provenza, F.D., Cook, D. 2016. Impacts of toxic plants on the welfare of grazing livestock. In:Villalba, J.J., editor. Animal Welfare in Extensive Production Systems. Sheffield, U.K.:5m Publishing. p. 78-102.
Is there a difference between exposures to one or two plant toxins? - (Abstract Only)
Welch, K.D. 2016. Is there a difference between exposures to one or two plant toxins?. American Society of Animal Science Annual Meeting. pp. 128 - https://asas.confex.com/asas/jam2016/webprogram/Paper15285.html.
Resistance to toxic plants: The right animal in the right pasture at the right time - (Abstract Only)
Green, B.T., Welch, K.D., Keele, J.W., Mcdaneld, T.G., Pfister, J.A. 2016. Resistance to toxic plants: The right animal in the right pasture at the right time. American Society of Animal Science Annual Meeting. 128 - https://asas.confex.com/asas/jam2016/webprogram/Paper15551.html.
A screen for Swainsonine in select North American Astragalus species - (Peer Reviewed Journal)
Cook, D., Gardner, D.R., Pfister, J.A., Lee, S.T., Welch, K.D., Welsh, S.L. 2017. A screen for Swainsonine in select North American Astragalus species. Chemistry and Biodiversity. 14(4):e1600364. doi: 10.1002/cbdv.201600364.
The effect of co-administration of death camas (Zigadenus spp.) and low larkspur (Delphinium spp.) in cattle Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Green, B.T., Gardner, D.R., Stonecipher, C.A., Pfister, J.A., Cook, D. 2016. The effect of co-administration of death camas (Zigadenus spp.) and low larkspur (Delphinium spp.) in cattle. Toxins. doi: 10.3390/toxins8010021.
The non-competitive blockade of GABAA receptors by an aqueous extract of water hemlock (Cicuta douglassi) tubers Reprint Icon - (Peer Reviewed Journal)
Green, B.T., Goulart, C., Welch, K.D., Pfister, J.A., Mccollum, I.J., Gardner, D.R. 2015. The non-competitive blockade of GABAA receptors by an aqueous extract of water hemlock (Cicuta douglassi) tubers. Toxicon. 108:11-14.
An evaluation of the toxicity of white snakeroot (Ageratina altissima) and rayless goldenrod (Isocoma pluriflora) in a lactating mouse model - (Peer Reviewed Journal)
Differences between Angus and Holstein cattle in the Lupinus leucophyllus induced inhibition of fetal activity Reprint Icon - (Peer Reviewed Journal)
Green, B.T., Panter, K.E., Lee, S.T., Welch, K.D., Pfister, J.A., Gardner, D.R., Stegelmeier, B.L., Davis, T.Z. 2015. Differences between Angus and Holstein cattle in the Lupinus leucophyllus induced inhibition of fetal activity. Toxicon. 106:1-6.
Adverse effects of larkspur (Delphinium spp.) on cattle Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Cook, D., Green, B.T., Gardner, D.R., Pfister, J.A., Mcdaneld, T.G., Panter, K.E. 2015. Adverse effects of larkspur (Delphinium spp.) on cattle. Agriculture. 5:456-474.
The effect of administering multiple doses of tall larkspur (Delphinium barbeyi) to cattle Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Green, B.T., Gardner, D.R., Cook, D., Pfister, J.A. 2015. The effect of administering multiple doses of tall larkspur (Delphinium barbeyi) to cattle. Journal of Animal Science. 93(8):4181-4188.
Effects of Juniperus species and stage of maturity on nutritional, in vitro digestibility, and plant secondary compound characteristics - (Peer Reviewed Journal)
Stewart, W.C., Whitney, T.R., Scholljegerdes, E.J., Naumann, H.D., Cherry, N.M., Muir, J., Lambert, B., Walker, J.W., Adams, R.P., Welch, K.D., Gardner, D.R., Estell, R.E. 2015. Effects of Juniperus species and stage of maturity on nutritional, in vitro digestibility, and plant secondary compound characteristics. Journal of Animal Science. 93:4034-4047.
Effects of juniperus species and stage of maturity on nutritional, in vitro digestibility, and plant secondary compound characteristics Reprint Icon - (Peer Reviewed Journal)
Stewart, W.C., Whitney, R.R., Scholljegerdes, E.J., Naumann, H.D., Cherry, N.M., Muir, J.P., Lambert, B.T., Walker, J.W., Adams, R.P., Welch, K.D., Gardner, D.R., Estell, R.E. 2015. Effects of juniperus species and stage of maturity on nutritional, in vitro digestibility, and plant secondary compound characteristics. Journal of Animal Science. 93(8):4034-4047.
The effect of multiple plant toxins on livestock - (Proceedings)
Welch, K.D., Green, B.T., Panter, K.E., Gardner, D.R., Pfister, J.A., Cook, D. 2015. The effect of multiple plant toxins on livestock. International Symposium on Poisonous Plants. 9:25-30.
Species susceptibility to locoweed poisoning and evaluation of chicks as a small animal model of poisoning - (Proceedings)
Stegelmeier, B.L., Davis, T.Z., Welch, K.D., Green, B.T., Gardner, D.R., Lee, S.T., Pfister, J.A., Cook, D., Panter, K.E. 2015. Species susceptibility to locoweed poisoning and evaluation of chicks as a small animal model of poisoning. International Symposium on Poisonous Plants. 9:126-129.
Pine needle abortion in cattle update: Metabolite detection in sera and fetal fluids from abortion case samples - (Proceedings)
Gardner, D.R., Panter, K.E., Aduriz, G., Snider, D., Welch, K.D., Stegelmeier, B.L. 2015. Pine needle abortion in cattle update: Metabolite detection in sera and fetal fluids from abortion case samples. International Symposium on Poisonous Plants. 9:301-306.
The clearance of delphinium alkaloids from the serum of cattle - (Proceedings)
Green, B.T., Welch, K.D., Gardner, D.R., Davis, T.Z., Stegelmeier, B.L., Lee, S.T. 2015. The clearance of delphinium alkaloids from the serum of cattle. International Symposium on Poisonous Plants. 9:296-306.
Agonist mediated fetal muscle-type nicotinic acetylcholine receptor desensitization - (Proceedings)
Green, B.T., Lee, S.T., Welch, K.D., Panter, K.E., Mccollum, I.J. 2015. Agonist mediated fetal muscle-type nicotinic acetylcholine receptor desensitization. International Symposium on Poisonous Plants. 9:296-300.
A monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and cyclopamine derivatives - (Proceedings)
Lee, S.T., Panter, K.E., Gardner, D.R., Green, B.T., Welch, K.D. 2015. A monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and cyclopamine derivatives. International Symposium on Poisonous Plants. 9:207-211.
Evaluation of the seasonal and annual abortifacient risk of western juniper trees on Oregon rangelands: Abortion risk of western juniper trees Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Parsons, C., Gardner, D.R., Deboodt, T., Shreder, P., Cook, D., Pfister, J.A., Panter, K.E. 2015. Evaluation of the seasonal and annual abortifacient risk of western juniper trees on Oregon rangelands: Abortion risk of western juniper trees. Rangelands. 37(4):139-143.
Safety concerns of herbal products and traditional Chinese herbal medicines: Dehydopyrrolizidine alkaloids and aristolochic acid - ()
Stegelmeier, B.L., Brown, A., Welch, K.D. 2015. Safety concerns of herbal products and traditional Chinese herbal medicines: Dehydopyrrolizidine alkaloids and aristolochic acid. Journal of Applied Toxicology. doi: 10.1002/jat.3192.
Safety concerns of herbal products and traditional Chinese herbal medicines: Dehydropyrrolizidine alkaloids and aristolochic acid Reprint Icon - (Peer Reviewed Journal)
Stegelmeier, B.L., Brown, A.W., Welch, K.D. 2015. Safety concerns of herbal products and traditional Chinese herbal medicines: Dehydropyrrolizidine alkaloids and aristolochic acid. Journal of Applied Toxicology. 35(12):1433-1437.
The serum concentrations of lupine alkaloids in orally-dosed Holstein cattle Reprint Icon - (Peer Reviewed Journal)
Green, B.T., Lee, S.T., Welch, K.D., Gardner, D.R., Stegelmeier, B.L., Davis, T.Z. 2015. The serum concentrations of lupine alkaloids in orally-dosed Holstein cattle. Research in Veterinary Science. 100:239-244.
The relative toxicity of Delphinium stachydeum in mice and cattle Reprint Icon - (Peer Reviewed Journal)
Cook, D., Welch, K.D., Green, B.T., Gardner, D.R., Pfister, J.A., Constantino, J., Stonecipher, C.A. 2015. The relative toxicity of Delphinium stachydeum in mice and cattle. Toxicon. 99:36-43.
Development of a PCR-based method for detection of Delphinium species in poisoned cattle Reprint Icon - (Peer Reviewed Journal)
Cook, D., Pfister, J.A., Constantino, J., Roper, J.M., Gardner, D.R., Welch, K.D., Hammond, Z.J., Green, B.T. 2015. Development of a PCR-based method for detection of Delphinium species in poisoned cattle. Journal of Agricultural and Food Chemistry. 63:1120-1125.
The effect of western juniper on the estrous cycle in beef cattle Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Stonecipher, C.A., Gardner, D.R., Panter, K.E., Parsons, C., Deboodt, T., Johnson, B. 2015. The effect of western juniper on the estrous cycle in beef cattle. Research in Veterinary Science. 98:16-18.
The effect of intermittent dosing of Nicotiana glauca on teratogenesis in goats Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Panter, K.E., Lee, S.T., Gardner, D.R. 2015. The effect of intermittent dosing of Nicotiana glauca on teratogenesis in goats. Toxicon. 93:119-124.
A study on embryonic death in goats due to Nicotiana glauca ingestion Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Lee, S.T., Panter, K.E., Gardner, D.R. 2014. A study on embryonic death in goats due to Nicotiana glauca ingestion. Toxicon. 90:64-69.
Studies on the teratogenicity of anabasine in a rat model Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Lee, S.T., Panter, K.E., Gardner, D.R., Knoppel, E.L., Green, B.T., Hammond, C.K., Hammond, Z.J., Pfister, J.A. 2014. Studies on the teratogenicity of anabasine in a rat model. Toxicon. 87:32-37.
Cyclopamine: From cyclops lambs to cancer treatment Reprint Icon - (Peer Reviewed Journal)
Lee, S.T., Welch, K.D., Panter, K.E., Gardner, D.R., Garrossian, M., Chang, C.T. 2014. Cyclopamine: From cyclops lambs to cancer treatment. Journal of Agricultural and Food Chemistry. 62(30):7355-7362.
Teratogenic effects of Mimosa tenuiflora in a rat model and possible role of N-methyl and N,N-dimethyltryptamine Reprint Icon - (Peer Reviewed Journal)
Gardner, D.R., Riet-Correa, F., Lemos, D., Welch, K.D., Pfister, J.A., Panter, K.E. 2014. Teratogenic effects of Mimosa tenuiflora in a rat model and possible role of N-methyl and N,N-dimethyltryptamine. Journal of Agricultural and Food Chemistry. 62(30):7398-7401.
If one plant toxin is harmful to livestock, what about two? Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Green, B.T., Panter, K.E., Gardner, D.R., Pfister, J.A., Cook, D. 2014. If one plant toxin is harmful to livestock, what about two? Journal of Agricultural and Food Chemistry. 62(30):7363-7369.
Mitigation of larkspur poisoning on rangelands through the selection of cattle Reprint Icon - (Peer Reviewed Journal)
Green, B.T., Welch, K.D., Pfister, J.A., Chitko-Mckown, C.G., Gardner, D.R., Panter, K.E. 2014. Mitigation of larkspur poisoning on rangelands through the selection of cattle. Rangelands. 36(1):10-15.
Plant alkaloids that cause developmental defects through the disruption of cholinergic neurotransmission Reprint Icon - (Peer Reviewed Journal)
Green, B.T., Lee, S.T., Welch, K.D., Panter, K.E. 2013. Plant alkaloids that cause developmental defects through the disruption of cholinergic neurotransmission. Birth Defects Research Part C: Embryo Today: Reviews. 99:235-246.
Poisonous plants: Effects on embryo and fetal development Reprint Icon - (Peer Reviewed Journal)
Panter, K.E., Welch, K.D., Gardner, D.R., Green, B.T. 2013. Poisonous plants: Effects on embryo and fetal development. Birth Defects Research Part C: Embryo Today: Reviews. 99:223-234.
Physiological and serum biochemical changes associated with rayless goldenrod (Isocoma pluriflora) poisoning in goats Reprint Icon - (Peer Reviewed Journal)
Davis, T.Z., Green, B.T., Stegelmeier, B.L., Lee, S.T., Welch, K.D., Pfister, J.A. 2013. Physiological and serum biochemical changes associated with rayless goldenrod (Isocoma pluriflora) poisoning in goats. Toxicon. 76:247-254.
Evaluation of the respiratory elimination kinetics of selenate and Se-methylselenocysteine after oral administration in lambs Reprint Icon - (Peer Reviewed Journal)
Davis, T.Z., Stegelmeier, B.L., Green, B.T., Welch, K.D., Hall, J.O. 2013. Evaluation of the respiratory elimination kinetics of selenate and Se-methylselenocysteine after oral administration in lambs. Research in Veterinary Science. 95(3):1163-1168.
The effect of low larkspur (Delphinium spp.) co-administration on the acute toxicity of death camas (Zigadenus spp.) in sheep Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Green, B.T., Gardner, D.R., Stonecipher, C.A., Panter, K.E., Pfister, J.A., Cook, D. 2013. The effect of low larkspur (Delphinium spp.) co-administration on the acute toxicity of death camas (Zigadenus spp.) in sheep. Toxicon. 76:50-58.
Plant toxins that affect nicotinic acetylcholine receptors: A review Reprint Icon - (Peer Reviewed Journal)
Green, B.T., Welch, K.D., Panter, K.E., Lee, S.T. 2013. Plant toxins that affect nicotinic acetylcholine receptors: A review. Chemical Research in Toxicology. 26(8):1129-1138.
A toxicokinetic comparison of two species of low larkspur (Delphinium spp.) in cattle Reprint Icon - (Peer Reviewed Journal)
Green, B.T., Welch, K.D., Gardner, D.R., Stegelmeier, B.L., Lee, S.T. 2013. A toxicokinetic comparison of two species of low larkspur (Delphinium spp.) in cattle. Research in Veterinary Science. 95(2):612-615.
The role of the a7 subunit of the nicotinic acetylcholine receptor on motor coordination in mice treated with methyllcaconitine and anabasine - (Peer Reviewed Journal)
Welch, K.D., Pfister, J.A., Gardner, D.R., Green, B.T., Panter, K.E. 2013. The role of the a7 subunit of the nicotinic acetylcholine receptor on motor coordination in mice treated with methyllcaconitine and anabasine. Journal of Applied Toxicology. 33(9):1017-26.
Comparative oral dose toxicokinetics of selenium compounds commonly found in selenium accumulator plants Reprint Icon - (Peer Reviewed Journal)
Davis, T.Z., Stegelmeier, B.L., Welch, K.D., Pfister, J.A., Panter, K.E., Hall, J.O. 2013. Comparative oral dose toxicokinetics of selenium compounds commonly found in selenium accumulator plants. Journal of Animal Science. 91(9):4501-4509.
Piperidine, pyridine alkaloid inhibition of fetal movement in a day 40 pregnant goat model Reprint Icon - (Peer Reviewed Journal)
Green, B.T., Lee, S.T., Welch, K.D., Pfister, J.A., Panter, K.E. 2013. Piperidine, pyridine alkaloid inhibition of fetal movement in a day 40 pregnant goat model. Food and Chemical Toxicology. 58:8-13.
Stereoselective potencies and relative toxicities of y-Coniceine and N-Methylconiine enantiomers - (Peer Reviewed Journal)
Lee, S.T., Green, B.T., Welch, K.D., Jordan, G.T., Zhang, Q., Panter, K.E., Hughes, D., Cheng-Wei, T.C., Pfister, J.A., Gardner, D.R. 2013. Stereoselective potencies and relative toxicities of y-Coniceine and N-Methylconiine enantiomers. Chemical Research in Toxicology. 23:616-21.
Evaluation of the seasonal and annual abortifacient risk of western juniper trees on Oregon rangelands - (Peer Reviewed Journal)
Welch, K.D., Cook, D., Gardner, D.R., Parsons, C., Pfister, J.A., Panter, K.E. 2013. A comparison of the abortifacient risk of western juniper trees in Oregon. Rangelands. 37(4):139-143. DOI: 10.1016/j.rala.2015.05.005.
Effect of a nicotinic acetylcholine receptor agonists and antagonists on motor function in mice - (Peer Reviewed Journal)
Welch, K.D., Pfister, J.A., Lima, F.G., Green, B.T., Gardner, D.R. 2013. Effect of a nicotinic acetylcholine receptor agonists and antagonists on motor function in mice. Journal of Toxicology and Applied Pharmacology. 266(3): 366-74.
Norditerpene alkaloid concentrations in tissues and floral rewards of larkspurs and impacts on pollinators - (Peer Reviewed Journal)
Cook, D., Manson, J.S., Gardner, D.R., Welch, K.D., Irwin, R.E. 2013. Norditerpene alkaloid concentrations in tissues and floral rewards of larkspurs and impacts on pollinators. Biochemical Systematics and Ecology. 48: 123-31.
The role of the a7 subunit of the nicotinic acetylcholine receptor in the acute toxicosis of methyllycaconitine in mice. - (Peer Reviewed Journal)
Welch, K.D., Green, B.T., Panter, K.E., Pfister, J.A., Gardner, D.R. 2013. The role of the a7 subunit of the nicotinic acetylcholine receptor in the acute toxicosis of methyllycaconitine in mice. Journal of Applied Toxicology. 33(9):1011-6.
Influence of endophyte genotype on swainsonine concentrations in Oxytropis sericea Reprint Icon - (Peer Reviewed Journal)
Cook, D., Grum, D.S., Gardner, D.R., Welch, K.D., Pfister, J.A. 2013. Influence of endophyte genotype on swainsonine concentrations in Oxytropis sericea. Toxicon. 61:105-11.
Fetal-muscle type nicotinic acetylcholine receptor activation in TE-671 cells, and inhibition of fetal movement in a day 40 pregnant goat model by optical isomers of the piperidine alkaloid coniine - (Peer Reviewed Journal)
Green, B.T., Lee, S.T., Welch, K.D., Pfister, J.A., Panter, K.E. 2013. Fetal-muscle type nicotinic acetylcholine receptor activation in TE-671 cells, and inhibition of fetal movement in a day 40 pregnant goat model by optical isomers of the piperidine alkaloid coniine. Journal of Pharmacology and Experimental Therapeutics. 344:1-13.
A comparison of the metabolism of the abortifacient compounds from Ponderosa Pine needles in conditioned versus naive cattle Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Gardner, D.R., Pfister, J.A., Panter, K.E., Zieglar, J., Hall, J. 2012. A comparison of the metabolism of the abortifacient compounds from Ponderosa Pine needles in conditioned versus naive cattle. Journal of Animal Science. 90(12): 4611-7.
Veratrum-induced placental dysplasia in sheep - (Peer Reviewed Journal)
Welch, K.D., Panter, K.E., Stegelmeier, B.L., Lee, S.T., Gardner, D.R., Cook, D. 2012. Veratrum-induced placental dysplasia in sheep. International Journal of Poisonous Plant Research. 2:54-62.
Development of a monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and cyclopamine-KAAD - (Peer Reviewed Journal)
Lee, S.T., Panter, K.E., Gardner, D.R., Green, B.T., Welch, K.D., Zhang, J., Change, C.T. 2012. Development of a monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and cyclopamine-KAAD. Journal of Pharmaceutical and Biomedical Analysis. 66: 282-6.
Poisonous Plants of the United States Reprint Icon - ()
Panter, K.E., Welch, K.D., Gardner, D.R., Lee, S.T., Green, B.T., Pfister, J.A., Cook, D., Davis, T.Z., Stegelmeier, B.L. 2012. Poisonous Plants of the United States. In: Guptra, R.C., editor. Veterinary Toxicology: Basic and Clinical Principles. 2nd edition. Boston, MA: Academic Press. p. 1031-79.
The good and the bad of poisonous plants: An introduction to the USDA-ARS Poisonous Plant Research Laboratory - (Peer Reviewed Journal)
Welch, K.D., Panter, K.E., Gardner, D.R., Stegelmeier, B.L. 2012. The good and the bad of poisonous plants: An introduction to the USDA-ARS Poisonous Plant Research Laboratory. Journal of Medical Toxicology. 8(2): 153-9.
Influence of phenological stage on swainsonine concentrations and endophyte amounts in Oxytropis sericea - (Peer Reviewed Journal)
Cook, D., Shi, L., Gardner, D.R., Pfister, J.A., Grum, D.S., Welch, K.D., Ralphs, M.H. 2012. Influence of phenological stage on swainsonine concentrations and endophyte amounts in Oxytropis sericea. Journal of Chemical Ecology. 38(2): 195-203.
The effect of 7,8-methylenedioxylycoctonine-type diterpenoid alkaloids on the toxicity of tall larkspur (Delphinium spp.) in cattle Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Green, B.T., Gardner, D.R., Cook, D., Pfister, J.A., Panter, K.E. 2012. The effect of 7,8-methylenedioxylycoctonine-type diterpenoid alkaloids on the toxicity of tall larkspur (Delphinium spp.) in cattle. Journal of Animal Science. 90(7): 2394-401.
Toxicokinetics of norditerpenoid alkaloids from low larkspur (Delphinium andersonii) orally administered in cattle Reprint Icon - (Peer Reviewed Journal)
Green, B.T., Welch, K.D., Gardner, D.R., Stegelmeier, B.L., Pfister, J.A., Cook, D., Panter, K.E. 2012. Toxicokinetics of norditerpenoid alkaloids from low larkspur (Delphinium andersonii) orally administered in cattle. American Journal of Veterinary Research. 73(8): 1318-24.
Benzofuran ketone dosage-dependent rayless goldenrod (Isocoma pluriflora) toxicosis in a caprine model - (Peer Reviewed Journal)
Alkaloid profiling as an approach to differentiate Lupinus garfieldensis, Lupinus sabinianus, and Lupinus sericeus Reprint Icon - (Peer Reviewed Journal)
Cook, D., Lee, S.T., Pfister, J.A., Stonecipher, C.A., Welch, K.D., Green, B.T., Panter, K.E. 2011. Alkaloid profiling as an approach to differentiate Lupinus garfieldensis, Lupinus sabinianus, and Lupinus sericeus. Phytochemical Analysis. 23(3): 278-84.
Potentiation of the actions of acetylcholine, epibatidine, and nicotine by methyllycaconitine at fetal muscle-type nicotinic acetylcholine receptors - (Peer Reviewed Journal)
Green, B.T., Welch, K.D., Cook, D., Gardner, D.R. 2011. Potentiation of the actions of acetylcholine, epibatidine, and nicotine by methyllycaconitine at fetal muscle-type nicotinic acetylcholine receptors. European Journal of Pharmacology. 662(1-3):15-21.
Toxic plants - ()
Panter, K.E., Welch, K.D., Gardner, D.R. 2011. Toxic plants. In: Gupta, R.C., editor. Reproductive and Developmental Toxicology. San Diego, CA. Academic Press. p. 689-705.
The effects of methyllycaconitine on the response of TE-671 cells to acetylcholine and epibatidine Reprint Icon - (Abstract Only)
Green, B.T., Welch, K.D., Cook, D., Gardner, D.R. 2011. The effects of methyllycaconitine on the response of TE-671 cells to acetylcholine and epibatidine. FASEB Journal. 25: 798.5.
Effect of MDL-type alkaloids on tall larkspur toxicosis - ()
Welch, K.D., Gardner, D.R., Panter, K.E., Green, B.T., Cook, D., Pfister, J.A., Stegelmeier, B.L., Davis, T.Z. 2011. Effect of MDL-type alkaloids on tall larkspur toxicosis. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA: CAB International. 94:540-9. DOI: 10.1079/9781845938338.0540.
Toxic plants: Effects on reproduction and fetal and embryonic development in livestock - ()
Panter, K.E., Welch, K.D., Gardner, D.R. 2011. Toxic plants: Effects on reproduction and fetal and embryonic development in livestock. In: Gupta, R.C., editor. Reproductive and Developmental Toxicology. San Diego, CA: Academic Press. p. 689-704.
Comparison of the toxic effects of two duncecap larkspur (Delphinium occidentale) chemotypes in mice and cattle - (Peer Reviewed Journal)
Cook, D., Green, B.T., Welch, K.D., Gardner, D.R., Pfister, J.A., Panter, K.E. 2011. Comparison of the toxic effects of two duncecap larkspur (Delphinium occidentale) chemotypes in mice and cattle. American Journal of Veterinary Research. 72(5):706-14.
The acute toxicity of the Death camas (Zigadenus spp.) alkaloid zygacine in mice, including the effect of methyllycaconitine co-administration on zygacine toxicity - (Peer Reviewed Journal)
Welch, K.D., Panter, K.E., Gardner, D.R., Stegelmeier, B.L., Green, B.T., Pfister, J.A., Cook, D. 2011. The acute toxicity of the Death camas (Zigadenus spp.) alkaloid zygacine in mice, including the effect of methyllycaconitine co-administration on zygacine toxicity. Journal of Animal Science. 89(5):1650-7.
Swainsonine and endophyte relationships in Astragalus mollissimus and Astragalus lentiginosus - (Peer Reviewed Journal)
Cook, D., Gardner, D.R., Grum, D.S., Pfister, J.A., Ralphs, M.H., Welch, K.D., Green, B.T. 2011. Swainsonine and endophyte relationships in Astragalus mollissimus and Astragalus lentiginosus. Journal of Agricultural and Food Chemistry. 59(4):1281-7.
Water hemlock poisoning in cattle: Ingestion of immature Cicuta maculata seed as the probable cause Reprint Icon - (Peer Reviewed Journal)
Panter, K.E., Gardner, D.R., Stegelmeier, B.L., Welch, K.D., Holstege, D. 2011. Water hemlock poisoning in cattle: Ingestion of immature Cicuta maculata seed as the probable cause. Toxicon. 57(1):157-61. DOI:10.1016/j.toxicon.2010.11.009
Western juniper-induced abortions in beef cattle Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Gardner, D.R., Panter, K.E., Stegelmeier, B.L., Parsons, C., Pfister, J.A., Cook, D. 2011. Western juniper-induced abortions in beef cattle. International Journal of Poisonous Plant Research. 1(1):72-9.
Lupine-Induced 'Crooked Calf Disease' in Washington and Oregon: Identification of the alkaloid profiles of Lupinus sericeus, Lupinus sulphureus, and Lupinus leucophyllus - ()
Cook, D., Lee, S.T., Gardner, D.R., Pfister, J.A., Welch, K.D., Green, B.T., Davis, T.Z., Panter, K.E. 2011. Lupine-Induced 'Crooked Calf Disease' in Washington and Oregon: Identification of the alkaloid profiles of Lupinus sericeus, Lupinus sulphureus and Lupinus leucophyllus. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. 97:566-71.
Distribution of Delphinium occidentale chemotypes and their potential toxicity - ()
Cook, D., Gardner, D.R., Pfister, J.A., Welch, K.D., Green, B.T., Lee, S.T. 2011. Distribution of Delphinium occidentale chemotypes and their potential toxicity. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. p. 606-11.
A toxicokinetic comparison of norditerpenoid alkaloids from Delphinium barbeyi and D. glaucescens in cattle Reprint Icon - (Peer Reviewed Journal)
Green, B.T., Welch, K.D., Gardner, D.R., Stegelmeier, B.L., Pfister, J.A., Cook, D., Davis, T.Z. 2011. A toxicokinetic comparison of norditerpenoid alkaloids from Delphinium barbeyi and D. glaucescens in cattle. Journal of Applied Toxicology. 31(1):20-6. DOI 10.1002/jat.1563.
Determination of the relative toxicity of enantiomers with cell-based assays - ()
Green, B.T., Lee, S.T., Welch, K.D., Panter, K.E., Kem, W. 2011. Determination of the relative toxicity of enantiomers with cell-based assays. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. 100:581-7.
The physiological effects and toxicokinetics of tall larkspur (Delphinium barbeyi) alkaloids in cattle - ()
Green, B.T., Welch, K.D., Pfister, J.A., Cook, D., Stegelmeier, B.L., Lee, S.T., Gardner, D.R., Panter, K.E. 2011. The physiological effects and toxicokinetics of tall larkspur (Delphinium barbeyi) alkaloids in cattle. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. p. 557-65.
Acute toxicity of selenium compounds commonly found in selenium-accumulator plants - ()
Davis, T.Z., Stegelmeier, B.L., Green, B.T., Welch, K.D., Panter, K.E., Hall, J.O. 2011. Acute toxicity of selenium compounds commonly found in selenium-accumulator plants. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. 91:525-31.
The Actions of Piperidine Alkaloids at Fetal Muscle-Type and Autonomic-Type Nicotinic Acetylcholine Receptors Reprint Icon - (Abstract Only)
Green, B.T., Lee, S.T., Panter, K.E., Welch, K.D., Cook, D., Pfister, J.A., Kem, W.R. 2010. The Actions of Piperidine Alkaloids at Fetal Muscle-Type and Autonomic-Type Nicotinic Acetylcholine Receptors. Experimental Biology.
Plants teratogenic to livestock in the United States - ()
Panter, K.E., Welch, K.D., Lee, S.T., Gardner, D.R., Stegelmeier, B.L., Ralphs, M.H., Davis, T.Z., Green, B.T., Pfister, J.A., Cook, D. 2011. Plants teratogenic to livestock in the United States. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. 36:236-42.
Effect of MDL-Type alkaloids on tall larkspur toxicosis - ()
Dose-response evaluation of Veratrum californicum in sheep - ()
Welch, K.D., Lee, S.T., Gardner, D.R., Panter, K.E., Stegelmeier, B.L., Cook, D. 2011. Dose-Response evaluation of Veratrum californicum in sheep. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. 37:243-50.
Differences in ponderosa pine isocupressic acid concentrations across space and time - (Peer Reviewed Journal)
Cook, D., Gardner, D.R., Pfister, J.A., Panter, K.E., Stegelmeier, B.L., Lee, S.T., Welch, K.D., Green, B.T., Davis, T.Z. 2010. Differences in ponderosa pine isocupressic acid concentrations across space and time. Rangelands. 32(2):14-7.
Actions of Piperidine Alkaloid Teratogens at Fetal Nicotinic Acetylcholine Receptors. Reprint Icon - (Peer Reviewed Journal)
Green, B.T., Lee, S.T., Panter, K.E., Welch, K.D., Cook, D., Pfister, J.A., Kem, W.R. 2010. Actions of Piperidine Alkaloid Teratogens at Fetal Nicotinic Acetylcholine Receptors. Neurotoxicology and Teratology. 32:383-390. Published online at: http://dx.doi.org/10.1016/j.ntt.2010.01.011
The comparative pathology of locoweed poisoning in horses and other livestock - ()
Stegelmeier, B.L., Davis, T.Z., Welch, K.D., Green, B.T., Gardner, D.R., Lee, S.T., Ralphs, M.H., Pfister, J.A., Cook, D., Panter, K.E. 2011. The comparative pathology of locoweed poisoning in horses and other livestock. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. 48:309-10.
Swainsonine Concentrations and Endophyte Amounts of Undifilum oxytropis in Different Plant Parts of Oxytropis sericea Reprint Icon - (Peer Reviewed Journal)
Cook, D., Gardner, D.R., Ralphs, M.H., Pfister, J.A., Welch, K.D., Green, B.T. 2009. Swainsonine Concentrations and Endophyte Amounts of Undifilum oxytropis in Different Plant Parts of Oxytropis sericea. Journal of Chemical Ecology, Vol. 35(10):1272-1278. (www.springerlink.com) DOI 0.1007/s10886-009-9710-9
Solutions to locoweed poisoning in New Mexico and the Western United States - (Peer Reviewed Journal)
Graham, D., Creamer, R., Cook, D., Stegelmeier, B.L., Welch, K.D., Pfister, J.A., Panter, K.E., Cibils, A., Ralphs, M.H., Encinias, M., Mc Daniel, K., Thompson, D., Gardner, K. 2009. Solutions to locoweed poisoning in New Mexico and the Western United States. Rangelands. 31(6):3-8.
Quantitative PCR Method to Measure the Fungal Endopyte in Locoweeds Reprint Icon - (Peer Reviewed Journal)
Cook, D., Gardner, D.R., Welch, K.D., Roper, J.M., Ralphs, M.H., Green, B.T. 2009. Quantitative PCR Method to Measure the Fungal Endopyte in Locoweeds. Journal of Agricultural and Food Chemistry. 57:6050-6054
Influence of 7, 8-methylenedioxylycoctonine-type Alkaloids on the Toxic Effects Associated with Ingestion of Tall Larkspurs (Delphinium spp.)in Cattle Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Green, B.T., Gardner, D.R., Cook, D., Pfister, J.A., Stegelmeier, B.L., Panter, K.E., Davis, T.Z. 2010. Influence of 7, 8-methylenedioxylycoctonine-type Alkaloids on the Toxic Effects Associated with Ingestion of Tall Larkspurs (Delphinium spp.)in Cattle. American Journal of Veterinary Research. Vol 71, No 4, pp 487-492.
The Biogeographical Distribution of Duncecap Larkspur (Delphinium occidentale) Chemotypes and Their Potential Toxicity Reprint Icon - (Peer Reviewed Journal)
Cook, D., Gardner, D.R., Pfister, J.A., Welch, K.D., Green, B.T., Lee, S.T. 2009. The Biogeographical Distribution of Duncecap Larkspur (Delphinium occidentale) Chemotypes and Their Potential Toxicity. Journal of Chemical Ecology 35:6443-652
Cyclopamine-induced Synophthalmia in Sheep: Defining a Critical Window and Toxicokinetic Evaluation Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Panter, K.E., Lee, S.T., Gardner, D.R., Stegelmeier, B.L., Cook, D. 2009. Cyclopamine-induced Synophthalmia in Sheep: Defining a Critical Window and Toxicokinetic Evaluation. Journal of Applied Toxicology, 29:414-421. (www.interscience.wiley.com) DOI 10.1002/jat.1427
The Effect of Poisonous Range Plants on Abortions in Livestock Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Davis, T.Z., Panter, K.E., Pfister, J.A., Green, B.T. 2009. The Effect of Poisonous Range Plants on Abortions in Livestock. Rangelands, 31(1):28-34. http://www.bioone.org/doi/pdf/10.2111/1551-501X-31.1.45?
Locoweed Poisoning in Cattle Reprint Icon - (Peer Reviewed Journal)
Cook, D., Ralphs, M.H., Welch, K.D., Stegelmeier, B.L. 2009. Locoweed Poisoning in Cattle. Rangelands, 31(1):16-21. http://www.bioone.org/doi/pdf/10.2111/1551-501X-31.1.45?
Identifying Plant Poisoning in Livestock Reprint Icon - (Peer Reviewed Journal)
Stegelmeier, B.L., Green, B.T., Panter, K.E., Welch, K.D., Hall, J.O. 2009. Identifying Plant Poisoning in Livestock. Rangelands 31(1):5-9 http://www.bioone.org/doi/pdf/10.2111/1551-501X-31.1.45?
Lupine Induced "Crooked Calf Disease": The Last 20 Years Reprint Icon - (Peer Reviewed Journal)
Lee, S.T., Panter, K.E., Gay, C., Pfister, J.A., Ralphs, M.H., Gardner, D.R., Stegelmeier, B.L., Motteram, E., Cook, D., Welch, K.D., Green, B.T., Davis, T.Z. 2008. Lupine Induced "Crooked Calf Disease": The Last 20 Years. Rangelands. 30(6): 13-8.
Value of Plant Diversity for Diet Mixing and Sequencing in Herbivores Reprint Icon - (Peer Reviewed Journal)
Provenza, F.D., Villalba, J.J., Wiedmeier, R.W., Layman, T., Owens, J., Lisonbee, L., Clemensen, A., Welch, K.D., Gardner, D.R., Lee, S.T. 2009. Value of Plant Diversity for Diet Mixing and Sequencing in Herbivores. Rangelands. 31(1):45-49. DOI:10.2111/1551-501X-31.1.45
The Alkaloid Profiles of Lupinus sulphureus Reprint Icon - (Peer Reviewed Journal)
Cook, D., Lee, S.T., Gardner, D.R., Pfister, J.A., Welch, K.D., Green, B.T., Davis, T.Z., Panter, K.E. 2009. The Alkaloid Profiles of Lupinus sulphureus. Journal of Agriculture and Food Chemistry, 57(4):1646-1653.
Investigation of the Susceptibility of Various Strains of Mice to Methyllycaconitine Toxicosis Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Green, B.T., Panter, K.E., Gardner, D.R., Pfister, J.A., Cook, D., Stegelmeier, B.L. 2009. Investigation of the Susceptibility of Various Strains of Mice to Methyllycaconitine Toxicosis. Journal of Animal Science, 87:1558-1564. doi:102527/jas.2008-1577
Serum Elimination Profiles of Methyllycaconitine and Deltaline in Cattle Following Oral Administration of Larkspur (Delphinium barbeyi) Reprint Icon - (Peer Reviewed Journal)
Green, B.T., Welch, K.D., Gardner, D.R., Stegelmeier, B.L., Davis, T.Z., Cook, D., Lee, S.T., Pfister, J.A., Panter, K.E. 2009. Serum Elimination Profiles of Methyllycaconitine and Deltaline in Cattle Following Oral Administration of Larkspur (Delphinium barbeyi). American Journal of Veterinary Research, 70(7):926-931.
Steroselective Potencies and Relative Toxicities of Coniine Enantiomers - (Peer Reviewed Journal)
Lee, S.T., Green, B.T., Welch, K.D., Pfister, J.A., Panter, K.E. 2008. Steroselective Potencies and Relative Toxicities of Coniine Enantiomers. Chemical Research in Toxicology. 21(10): 2061-2064. DOI 10.1021/tx800229w
Effect of body condition on consumption of pine needles (Pinus ponderosa) by beef cows - (Peer Reviewed Journal)
Pfister, J.A., Panter, K.E., Gardner, D.R., Cook, D., Welch, K.D. 2008. Effect of body condition on consumption of pine needles (Pinus ponderosa) by beef cows. Journal of Animal Science. 86:3608-16. DOI: 10.2527/jas.2008-1000.
The effect of 7, 8-Methylenedioxylycoctonine -Type Diterpenoid Alkaloids on the Toxicity of Methyllycaconitine in Mice Reprint Icon - (Peer Reviewed Journal)
Welch, K.D., Panter, K.E., Gardner, D.R., Green, B.T., Pfister, J.A., Cook, D., Stegelmeier, B.L. 2008. The effect of 7, 8-Methylenedioxylycoctonine -Type Diterpenoid Alkaloids on the Toxicity of Ethyllycaconitine in Mice. Journal of Animal Science, J. Anim. Sci. 86:2761-2770.
Effects of Larkspur (Delphinium barbeyi) on Heart Rate and Electrically Evoked Electromyographic Response of the External Anal Sphincter in Cattle. Reprint Icon - (Peer Reviewed Journal)
Green, B.T., Pfister, J.A., Cook, D., Welch, K.D., Stegelmeier, B.L., Lee, S.T., Gardner, D.R., Knoppel, E.L., Panter, K.E. 2009. Effects of Larkspur (Delphinium barbeyi) on Heart Rate and Electrically Evoked Electromyographic Response of the External Anal Sphincter in Cattle. American Journal of Veterinary Research. 70(4):539-546
The effect of body condition on serum concentrations of two teratogenic alkaloids (anagyrine and ammodendrine) from Lupines (Lupinus spp.) that cause crooked calf disease. Reprint Icon - (Peer Reviewed Journal)
Lee, S.T., Panter, K.E., Pfister, J.A., Gardner, D.R., Welch, K.D. 2008. The Effect of Body Condition on Serum Concentrations of Two Teratogenic Alkaloids (Anagyrine and Ammodendrine) From Lupines (Lupinus spp.) That Cause Crooked Calf Disease. Journal of Animal Science. 86:2771-2778 doi:10.2527/jas.2007-0610.
The Effect of High Deltaline Concentration on the Toxicity of Methyllycaconitine in Mice - (Abstract Only)
Welch, K.D., Panter, K.E., Gardner, D.R., Green, B.T., Pfister, J.A., Cook, D. 2008. The Effect of High Deltaline Concentration on the Toxicity of Methyllycaconitine in Mice. International Society on Toxicology Meeting.
Last Modified: 05/23/2017
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