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United States Department of Agriculture

Agricultural Research Service

Kevin Welch
Res Toxclgst


Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
USDA-ARS Poisonous Plant Research Laboratory: History and current research on western North American rangelands -
Comparison of the serum toxicokinetics of larkspur toxins in cattle, sheep and goats Reprint Icon -
Welch, K.D., Gardner, D.R., Green, B.T., Stonecipher, C.A., Cook, D., Pfister, J.A. 2016. Comparison of the serum toxicokinetics of larkspur toxins in cattle, sheep and goats. Toxicon. 119:270-273.
Activation and desensitization of peripheral muscle and neuronal nicotinic acetylcholine receptors by selected, naturally-occurring pyridine alkaloids Reprint Icon -
Green, B.T., Lee, S.T., Welch, K.D., Cook, D., Kem, W.R. 2016. Activation and desensitization of peripheral muscle and neuronal nicotinic acetylcholine receptors by selected, naturally-occurring pyridine alkaloids. Toxins. doi: 10.1016/j.toxicon.2015.09.015.
Impacts of toxic plants on the welfare of grazing livestock -
Pfister, J.A., Green, B.T., Welch, K.D., Provenza, F.D., Cook, D. 2016. Impacts of toxic plants on the welfare of grazing livestock. In:Villalba, J.J., editor. Animal Welfare in Extensive Production Systems. Sheffield, U.K.:5m Publishing. p. 78-102.
Is there a difference between exposures to one or two plant toxins? -
Welch, K.D. 2016. Is there a difference between exposures to one or two plant toxins?. American Society of Animal Science Annual Meeting. pp. 128 - https://asas.confex.com/asas/jam2016/webprogram/Paper15285.html.
Resistance to toxic plants: The right animal in the right pasture at the right time -
Green, B.T., Welch, K.D., Keele, J.W., Mcdaneld, T.G., Pfister, J.A. 2016. Resistance to toxic plants: The right animal in the right pasture at the right time. American Society of Animal Science Annual Meeting. 128 - https://asas.confex.com/asas/jam2016/webprogram/Paper15551.html.
The effect of co-administration of death camas (Zigadenus spp.) and low larkspur (Delphinium spp.) in cattle Reprint Icon -
Welch, K.D., Green, B.T., Gardner, D.R., Stonecipher, C.A., Pfister, J.A., Cook, D. 2016. The effect of co-administration of death camas (Zigadenus spp.) and low larkspur (Delphinium spp.) in cattle. Toxins. doi: 10.3390/toxins8010021.
The non-competitive blockade of GABAA receptors by an aqueous extract of water hemlock (Cicuta douglassi) tubers Reprint Icon -
Green, B.T., Goulart, C., Welch, K.D., Pfister, J.A., Mccollum, I.J., Gardner, D.R. 2015. The non-competitive blockade of GABAA receptors by an aqueous extract of water hemlock (Cicuta douglassi) tubers. Toxicon. 108:11-14.
An evaluation of the toxicity of white snakeroot (Ageratina altissima) and rayless goldenrod (Isocoma pluriflora) in a lactating mouse model -
Differences between Angus and Holstein cattle in the Lupinus leucophyllus induced inhibition of fetal activity Reprint Icon -
Green, B.T., Panter, K.E., Lee, S.T., Welch, K.D., Pfister, J.A., Gardner, D.R., Stegelmeier, B.L., Davis, T.Z. 2015. Differences between Angus and Holstein cattle in the Lupinus leucophyllus induced inhibition of fetal activity. Toxicon. 106:1-6.
Adverse effects of larkspur (Delphinium spp.) on cattle Reprint Icon -
Welch, K.D., Cook, D., Green, B.T., Gardner, D.R., Pfister, J.A., Mcdaneld, T.G., Panter, K.E. 2015. Adverse effects of larkspur (Delphinium spp.) on cattle. Agriculture. 5:456-474.
The effect of administering multiple doses of tall larkspur (Delphinium barbeyi) to cattle Reprint Icon -
Welch, K.D., Green, B.T., Gardner, D.R., Cook, D., Pfister, J.A. 2015. The effect of administering multiple doses of tall larkspur (Delphinium barbeyi) to cattle. Journal of Animal Science. 93(8):4181-4188.
Effects of Juniperus species and stage of maturity on nutritional, in vitro digestibility, and plant secondary compound characteristics -
Stewart, W.C., Whitney, T.R., Scholljegerdes, E.J., Naumann, H.D., Cherry, N.M., Muir, J., Lambert, B., Walker, J.W., Adams, R.P., Welch, K.D., Gardner, D.R., Estell, R.E. 2015. Effects of Juniperus species and stage of maturity on nutritional, in vitro digestibility, and plant secondary compound characteristics. Journal of Animal Science. 93:4034-4047.
Effects of juniperus species and stage of maturity on nutritional, in vitro digestibility, and plant secondary compound characteristics Reprint Icon -
Stewart, W.C., Whitney, R.R., Scholljegerdes, E.J., Naumann, H.D., Cherry, N.M., Muir, J.P., Lambert, B.T., Walker, J.W., Adams, R.P., Welch, K.D., Gardner, D.R., Estell, R.E. 2015. Effects of juniperus species and stage of maturity on nutritional, in vitro digestibility, and plant secondary compound characteristics. Journal of Animal Science. 93(8):4034-4047.
The effect of multiple plant toxins on livestock -
Welch, K.D., Green, B.T., Panter, K.E., Gardner, D.R., Pfister, J.A., Cook, D. 2015. The effect of multiple plant toxins on livestock. International Symposium on Poisonous Plants. 9:25-30.
Species susceptibility to locoweed poisoning and evaluation of chicks as a small animal model of poisoning -
Stegelmeier, B.L., Davis, T.Z., Welch, K.D., Green, B.T., Gardner, D.R., Lee, S.T., Pfister, J.A., Cook, D., Panter, K.E. 2015. Species susceptibility to locoweed poisoning and evaluation of chicks as a small animal model of poisoning. International Symposium on Poisonous Plants. 9:126-129.
Pine needle abortion in cattle update: Metabolite detection in sera and fetal fluids from abortion case samples -
Gardner, D.R., Panter, K.E., Aduriz, G., Snider, D., Welch, K.D., Stegelmeier, B.L. 2015. Pine needle abortion in cattle update: Metabolite detection in sera and fetal fluids from abortion case samples. International Symposium on Poisonous Plants. 9:301-306.
The clearance of delphinium alkaloids from the serum of cattle -
Green, B.T., Welch, K.D., Gardner, D.R., Davis, T.Z., Stegelmeier, B.L., Lee, S.T. 2015. The clearance of delphinium alkaloids from the serum of cattle. International Symposium on Poisonous Plants. 9:296-306.
Agonist mediated fetal muscle-type nicotinic acetylcholine receptor desensitization -
Green, B.T., Lee, S.T., Welch, K.D., Panter, K.E., Mccollum, I.J. 2015. Agonist mediated fetal muscle-type nicotinic acetylcholine receptor desensitization. International Symposium on Poisonous Plants. 9:296-300.
A monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and cyclopamine derivatives -
Lee, S.T., Panter, K.E., Gardner, D.R., Green, B.T., Welch, K.D. 2015. A monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and cyclopamine derivatives. International Symposium on Poisonous Plants. 9:207-211.
Evaluation of the seasonal and annual abortifacient risk of western juniper trees on Oregon rangelands: Abortion risk of western juniper trees Reprint Icon -
Welch, K.D., Parsons, C., Gardner, D.R., Deboodt, T., Shreder, P., Cook, D., Pfister, J.A., Panter, K.E. 2015. Evaluation of the seasonal and annual abortifacient risk of western juniper trees on Oregon rangelands: Abortion risk of western juniper trees. Rangelands. 37(4):139-143.
Safety concerns of herbal products and traditional Chinese herbal medicines: Dehydopyrrolizidine alkaloids and aristolochic acid -
Stegelmeier, B.L., Brown, A., Welch, K.D. 2015. Safety concerns of herbal products and traditional Chinese herbal medicines: Dehydopyrrolizidine alkaloids and aristolochic acid. Journal of Applied Toxicology. doi: 10.1002/jat.3192.
Safety concerns of herbal products and traditional Chinese herbal medicines: Dehydropyrrolizidine alkaloids and aristolochic acid -
Stegelmeier, B.L., Brown, A.W., Welch, K.D. 2015. Safety concerns of herbal products and traditional Chinese herbal medicines: Dehydropyrrolizidine alkaloids and aristolochic acid. Journal of Applied Toxicology. 35(12):1433-1437.
The serum concentrations of lupine alkaloids in orally-dosed Holstein cattle Reprint Icon -
Green, B.T., Lee, S.T., Welch, K.D., Gardner, D.R., Stegelmeier, B.L., Davis, T.Z. 2015. The serum concentrations of lupine alkaloids in orally-dosed Holstein cattle. Research in Veterinary Science. 100:239-244.
The relative toxicity of Delphinium stachydeum in mice and cattle -
Cook, D., Welch, K.D., Green, B.T., Gardner, D.R., Pfister, J.A., Constantino, J., Stonecipher, C.A. 2015. The relative toxicity of Delphinium stachydeum in mice and cattle. Toxicon. 99:36-43.
Development of a PCR-based method for detection of Delphinium species in poisoned cattle -
Cook, D., Pfister, J.A., Constantino, J., Roper, J.M., Gardner, D.R., Welch, K.D., Hammond, Z.J., Green, B.T. 2015. Development of a PCR-based method for detection of Delphinium species in poisoned cattle. Journal of Agricultural and Food Chemistry. 63:1120-1125.
The effect of western juniper on the estrous cycle in beef cattle Reprint Icon -
Welch, K.D., Stonecipher, C.A., Gardner, D.R., Panter, K.E., Parsons, C., Deboodt, T., Johnson, B. 2015. The effect of western juniper on the estrous cycle in beef cattle. Research in Veterinary Science. 98:16-18.
The effect of intermittent dosing of Nicotiana glauca on teratogenesis in goats -
Welch, K.D., Panter, K.E., Lee, S.T., Gardner, D.R. 2015. The effect of intermittent dosing of Nicotiana glauca on teratogenesis in goats. Toxicon. 93:119-124.
A study on embryonic death in goats due to Nicotiana glauca ingestion Reprint Icon -
Welch, K.D., Lee, S.T., Panter, K.E., Gardner, D.R. 2014. A study on embryonic death in goats due to Nicotiana glauca ingestion. Toxicon. 90:64-69.
Studies on the teratogenicity of anabasine in a rat model Reprint Icon -
Welch, K.D., Lee, S.T., Panter, K.E., Gardner, D.R., Knoppel, E.L., Green, B.T., Hammond, C.K., Hammond, Z.J., Pfister, J.A. 2014. Studies on the teratogenicity of anabasine in a rat model. Toxicon. 87:32-37.
Cyclopamine: From cyclops lambs to cancer treatment Reprint Icon -
Lee, S.T., Welch, K.D., Panter, K.E., Gardner, D.R., Garrossian, M., Chang, C.T. 2014. Cyclopamine: From cyclops lambs to cancer treatment. Journal of Agricultural and Food Chemistry. 62(30):7355-7362.
Teratogenic effects of Mimosa tenuiflora in a rat model and possible role of N-methyl and N,N-dimethyltryptamine Reprint Icon -
Gardner, D.R., Riet-Correa, F., Lemos, D., Welch, K.D., Pfister, J.A., Panter, K.E. 2014. Teratogenic effects of Mimosa tenuiflora in a rat model and possible role of N-methyl and N,N-dimethyltryptamine. Journal of Agricultural and Food Chemistry. 62(30):7398-7401.
If one plant toxin is harmful to livestock, what about two? Reprint Icon -
Welch, K.D., Green, B.T., Panter, K.E., Gardner, D.R., Pfister, J.A., Cook, D. 2014. If one plant toxin is harmful to livestock, what about two? Journal of Agricultural and Food Chemistry. 62(30):7363-7369.
Mitigation of larkspur poisoning on rangelands through the selection of cattle -
Green, B.T., Welch, K.D., Pfister, J.A., Chitko-Mckown, C.G., Gardner, D.R., Panter, K.E. 2014. Mitigation of larkspur poisoning on rangelands through the selection of cattle. Rangelands. 36(1):10-15.
Plant alkaloids that cause developmental defects through the disruption of cholinergic neurotransmission -
Green, B.T., Lee, S.T., Welch, K.D., Panter, K.E. 2013. Plant alkaloids that cause developmental defects through the disruption of cholinergic neurotransmission. Birth Defects Research Part C: Embryo Today: Reviews. 99:235-246.
Poisonous plants: Effects on embryo and fetal development -
Panter, K.E., Welch, K.D., Gardner, D.R., Green, B.T. 2013. Poisonous plants: Effects on embryo and fetal development. Birth Defects Research Part C: Embryo Today: Reviews. 99:223-234.
Physiological and serum biochemical changes associated with rayless goldenrod (Isocoma pluriflora) poisoning in goats -
Davis, T.Z., Green, B.T., Stegelmeier, B.L., Lee, S.T., Welch, K.D., Pfister, J.A. 2013. Physiological and serum biochemical changes associated with rayless goldenrod (Isocoma pluriflora) poisoning in goats. Toxicon. 76:247-254.
Evaluation of the respiratory elimination kinetics of selenate and Se-methylselenocysteine after oral administration in lambs -
Davis, T.Z., Stegelmeier, B.L., Green, B.T., Welch, K.D., Hall, J.O. 2013. Evaluation of the respiratory elimination kinetics of selenate and Se-methylselenocysteine after oral administration in lambs. Research in Veterinary Science. 95(3):1163-1168.
The effect of low larkspur (Delphinium spp.) co-administration on the acute toxicity of death camas (Zigadenus spp.) in sheep Reprint Icon -
Welch, K.D., Green, B.T., Gardner, D.R., Stonecipher, C.A., Panter, K.E., Pfister, J.A., Cook, D. 2013. The effect of low larkspur (Delphinium spp.) co-administration on the acute toxicity of death camas (Zigadenus spp.) in sheep. Toxicon. 76:50-58.
Plant toxins that affect nicotinic acetylcholine receptors: A review Reprint Icon -
Green, B.T., Welch, K.D., Panter, K.E., Lee, S.T. 2013. Plant toxins that affect nicotinic acetylcholine receptors: A review. Chemical Research in Toxicology. 26(8):1129-1138.
A toxicokinetic comparison of two species of low larkspur (Delphinium spp.) in cattle Reprint Icon -
Green, B.T., Welch, K.D., Gardner, D.R., Stegelmeier, B.L., Lee, S.T. 2013. A toxicokinetic comparison of two species of low larkspur (Delphinium spp.) in cattle. Research in Veterinary Science. 95(2):612-615.
The role of the a7 subunit of the nicotinic acetylcholine receptor on motor coordination in mice treated with methyllcaconitine and anabasine -
Welch, K.D., Pfister, J.A., Gardner, D.R., Green, B.T., Panter, K.E. 2013. The role of the a7 subunit of the nicotinic acetylcholine receptor on motor coordination in mice treated with methyllcaconitine and anabasine. Journal of Applied Toxicology. 33(9):1017-26.
Comparative oral dose toxicokinetics of selenium compounds commonly found in selenium accumulator plants -
Davis, T.Z., Stegelmeier, B.L., Welch, K.D., Pfister, J.A., Panter, K.E., Hall, J.O. 2013. Comparative oral dose toxicokinetics of selenium compounds commonly found in selenium accumulator plants. Journal of Animal Science. 91(9):4501-4509.
Piperidine, pyridine alkaloid inhibition of fetal movement in a day 40 pregnant goat model -
Green, B.T., Lee, S.T., Welch, K.D., Pfister, J.A., Panter, K.E. 2013. Piperidine, pyridine alkaloid inhibition of fetal movement in a day 40 pregnant goat model. Food and Chemical Toxicology. 58:8-13.
Stereoselective potencies and relative toxicities of y-Coniceine and N-Methylconiine enantiomers -
Lee, S.T., Green, B.T., Welch, K.D., Jordan, G.T., Zhang, Q., Panter, K.E., Hughes, D., Cheng-Wei, T.C., Pfister, J.A., Gardner, D.R. 2013. Stereoselective potencies and relative toxicities of y-Coniceine and N-Methylconiine enantiomers. Chemical Research in Toxicology. 23:616-21.
Evaluation of the seasonal and annual abortifacient risk of western juniper trees on Oregon rangelands -
Welch, K.D., Cook, D., Gardner, D.R., Parsons, C., Pfister, J.A., Panter, K.E. 2013. A comparison of the abortifacient risk of western juniper trees in Oregon. Rangelands. 37(4):139-143. DOI: 10.1016/j.rala.2015.05.005.
Effect of a nicotinic acetylcholine receptor agonists and antagonists on motor function in mice -
Welch, K.D., Pfister, J.A., Lima, F.G., Green, B.T., Gardner, D.R. 2013. Effect of a nicotinic acetylcholine receptor agonists and antagonists on motor function in mice. Journal of Toxicology and Applied Pharmacology. 266(3): 366-74.
Norditerpene alkaloid concentrations in tissues and floral rewards of larkspurs and impacts on pollinators -
Cook, D., Manson, J.S., Gardner, D.R., Welch, K.D., Irwin, R.E. 2013. Norditerpene alkaloid concentrations in tissues and floral rewards of larkspurs and impacts on pollinators. Biochemical Systematics and Ecology. 48: 123-31.
The role of the a7 subunit of the nicotinic acetylcholine receptor in the acute toxicosis of methyllycaconitine in mice. -
Welch, K.D., Green, B.T., Panter, K.E., Pfister, J.A., Gardner, D.R. 2013. The role of the a7 subunit of the nicotinic acetylcholine receptor in the acute toxicosis of methyllycaconitine in mice. Journal of Applied Toxicology. 33(9):1011-6.
Influence of endophyte genotype on swainsonine concentrations in Oxytropis sericea Reprint Icon -
Cook, D., Grum, D.S., Gardner, D.R., Welch, K.D., Pfister, J.A. 2013. Influence of endophyte genotype on swainsonine concentrations in Oxytropis sericea. Toxicon. 61:105-11.
Fetal-muscle type nicotinic acetylcholine receptor activation in TE-671 cells, and inhibition of fetal movement in a day 40 pregnant goat model by optical isomers of the piperidine alkaloid coniine -
Green, B.T., Lee, S.T., Welch, K.D., Pfister, J.A., Panter, K.E. 2013. Fetal-muscle type nicotinic acetylcholine receptor activation in TE-671 cells, and inhibition of fetal movement in a day 40 pregnant goat model by optical isomers of the piperidine alkaloid coniine. Journal of Pharmacology and Experimental Therapeutics. 344:1-13.
A comparison of the metabolism of the abortifacient compounds from Ponderosa Pine needles in conditioned versus naive cattle Reprint Icon -
Welch, K.D., Gardner, D.R., Pfister, J.A., Panter, K.E., Zieglar, J., Hall, J. 2012. A comparison of the metabolism of the abortifacient compounds from Ponderosa Pine needles in conditioned versus naive cattle. Journal of Animal Science. 90(12): 4611-7.
Veratrum-induced placental dysplasia in sheep -
Welch, K.D., Panter, K.E., Stegelmeier, B.L., Lee, S.T., Gardner, D.R., Cook, D. 2012. Veratrum-induced placental dysplasia in sheep. International Journal of Poisonous Plant Research. 2:54-62.
Development of a monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and cyclopamine-KAAD -
Lee, S.T., Panter, K.E., Gardner, D.R., Green, B.T., Welch, K.D., Zhang, J., Change, C.T. 2012. Development of a monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and cyclopamine-KAAD. Journal of Pharmaceutical and Biomedical Analysis. 66: 282-6.
Poisonous Plants of the United States Reprint Icon -
Panter, K.E., Welch, K.D., Gardner, D.R., Lee, S.T., Green, B.T., Pfister, J.A., Cook, D., Davis, T.Z., Stegelmeier, B.L. 2012. Poisonous Plants of the United States. In: Guptra, R.C., editor. Veterinary Toxicology: Basic and Clinical Principles. 2nd edition. Boston, MA: Academic Press. p. 1031-79.
The good and the bad of poisonous plants: An introduction to the USDA-ARS Poisonous Plant Research Laboratory -
Welch, K.D., Panter, K.E., Gardner, D.R., Stegelmeier, B.L. 2012. The good and the bad of poisonous plants: An introduction to the USDA-ARS Poisonous Plant Research Laboratory. Journal of Medical Toxicology. 8(2): 153-9.
Influence of phenological stage on swainsonine concentrations and endophyte amounts in Oxytropis sericea -
Cook, D., Shi, L., Gardner, D.R., Pfister, J.A., Grum, D.S., Welch, K.D., Ralphs, M.H. 2012. Influence of phenological stage on swainsonine concentrations and endophyte amounts in Oxytropis sericea. Journal of Chemical Ecology. 38(2): 195-203.
The effect of 7,8-methylenedioxylycoctonine-type diterpenoid alkaloids on the toxicity of tall larkspur (Delphinium spp.) in cattle Reprint Icon -
Welch, K.D., Green, B.T., Gardner, D.R., Cook, D., Pfister, J.A., Panter, K.E. 2012. The effect of 7,8-methylenedioxylycoctonine-type diterpenoid alkaloids on the toxicity of tall larkspur (Delphinium spp.) in cattle. Journal of Animal Science. 90(7): 2394-401.
Toxicokinetics of norditerpenoid alkaloids from low larkspur (Delphinium andersonii) orally administered in cattle Reprint Icon -
Green, B.T., Welch, K.D., Gardner, D.R., Stegelmeier, B.L., Pfister, J.A., Cook, D., Panter, K.E. 2012. Toxicokinetics of norditerpenoid alkaloids from low larkspur (Delphinium andersonii) orally administered in cattle. American Journal of Veterinary Research. 73(8): 1318-24.
Benzofuran ketone dosage-dependent rayless goldenrod (Isocoma pluriflora) toxicosis in a caprine model -
Alkaloid profiling as an approach to differentiate Lupinus garfieldensis, Lupinus sabinianus, and Lupinus sericeus Reprint Icon -
Cook, D., Lee, S.T., Pfister, J.A., Stonecipher, C.A., Welch, K.D., Green, B.T., Panter, K.E. 2011. Alkaloid profiling as an approach to differentiate Lupinus garfieldensis, Lupinus sabinianus, and Lupinus sericeus. Phytochemical Analysis. 23(3): 278-84.
Potentiation of the actions of acetylcholine, epibatidine, and nicotine by methyllycaconitine at fetal muscle-type nicotinic acetylcholine receptors -
Green, B.T., Welch, K.D., Cook, D., Gardner, D.R. 2011. Potentiation of the actions of acetylcholine, epibatidine, and nicotine by methyllycaconitine at fetal muscle-type nicotinic acetylcholine receptors. European Journal of Pharmacology. 662(1-3):15-21.
Toxic plants -
Panter, K.E., Welch, K.D., Gardner, D.R. 2011. Toxic plants. In: Gupta, R.C., editor. Reproductive and Developmental Toxicology. San Diego, CA. Academic Press. p. 689-705.
The effects of methyllycaconitine on the response of TE-671 cells to acetylcholine and epibatidine Reprint Icon -
Green, B.T., Welch, K.D., Cook, D., Gardner, D.R. 2011. The effects of methyllycaconitine on the response of TE-671 cells to acetylcholine and epibatidine. FASEB Journal. 25: 798.5.
Effect of MDL-type alkaloids on tall larkspur toxicosis -
Welch, K.D., Gardner, D.R., Panter, K.E., Green, B.T., Cook, D., Pfister, J.A., Stegelmeier, B.L., Davis, T.Z. 2011. Effect of MDL-type alkaloids on tall larkspur toxicosis. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA: CAB International. 94:540-9. DOI: 10.1079/9781845938338.0540.
Toxic plants: Effects on reproduction and fetal and embryonic development in livestock -
Panter, K.E., Welch, K.D., Gardner, D.R. 2011. Toxic plants: Effects on reproduction and fetal and embryonic development in livestock. In: Gupta, R.C., editor. Reproductive and Developmental Toxicology. San Diego, CA: Academic Press. p. 689-704.
Comparison of the toxic effects of two duncecap larkspur (Delphinium occidentale) chemotypes in mice and cattle -
Cook, D., Green, B.T., Welch, K.D., Gardner, D.R., Pfister, J.A., Panter, K.E. 2011. Comparison of the toxic effects of two duncecap larkspur (Delphinium occidentale) chemotypes in mice and cattle. American Journal of Veterinary Research. 72(5):706-14.
The acute toxicity of the Death camas (Zigadenus spp.) alkaloid zygacine in mice, including the effect of methyllycaconitine co-administration on zygacine toxicity -
Welch, K.D., Panter, K.E., Gardner, D.R., Stegelmeier, B.L., Green, B.T., Pfister, J.A., Cook, D. 2011. The acute toxicity of the Death camas (Zigadenus spp.) alkaloid zygacine in mice, including the effect of methyllycaconitine co-administration on zygacine toxicity. Journal of Animal Science. 89(5):1650-7.
Swainsonine and endophyte relationships in Astragalus mollissimus and Astragalus lentiginosus -
Cook, D., Gardner, D.R., Grum, D.S., Pfister, J.A., Ralphs, M.H., Welch, K.D., Green, B.T. 2011. Swainsonine and endophyte relationships in Astragalus mollissimus and Astragalus lentiginosus. Journal of Agricultural and Food Chemistry. 59(4):1281-7.
Water hemlock poisoning in cattle: Ingestion of immature Cicuta maculata seed as the probable cause Reprint Icon -
Panter, K.E., Gardner, D.R., Stegelmeier, B.L., Welch, K.D., Holstege, D. 2011. Water hemlock poisoning in cattle: Ingestion of immature Cicuta maculata seed as the probable cause. Toxicon. 57(1):157-61. DOI:10.1016/j.toxicon.2010.11.009
Western juniper-induced abortions in beef cattle Reprint Icon -
Welch, K.D., Gardner, D.R., Panter, K.E., Stegelmeier, B.L., Parsons, C., Pfister, J.A., Cook, D. 2011. Western juniper-induced abortions in beef cattle. International Journal of Poisonous Plant Research. 1(1):72-9.
Lupine-Induced 'Crooked Calf Disease' in Washington and Oregon: Identification of the alkaloid profiles of Lupinus sericeus, Lupinus sulphureus, and Lupinus leucophyllus -
Cook, D., Lee, S.T., Gardner, D.R., Pfister, J.A., Welch, K.D., Green, B.T., Davis, T.Z., Panter, K.E. 2011. Lupine-Induced 'Crooked Calf Disease' in Washington and Oregon: Identification of the alkaloid profiles of Lupinus sericeus, Lupinus sulphureus and Lupinus leucophyllus. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. 97:566-71.
Distribution of Delphinium occidentale chemotypes and their potential toxicity -
Cook, D., Gardner, D.R., Pfister, J.A., Welch, K.D., Green, B.T., Lee, S.T. 2011. Distribution of Delphinium occidentale chemotypes and their potential toxicity. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. p. 606-11.
A toxicokinetic comparison of norditerpenoid alkaloids from Delphinium barbeyi and D. glaucescens in cattle Reprint Icon -
Green, B.T., Welch, K.D., Gardner, D.R., Stegelmeier, B.L., Pfister, J.A., Cook, D., Davis, T.Z. 2011. A toxicokinetic comparison of norditerpenoid alkaloids from Delphinium barbeyi and D. glaucescens in cattle. Journal of Applied Toxicology. 31(1):20-6. DOI 10.1002/jat.1563.
Determination of the relative toxicity of enantiomers with cell-based assays -
Green, B.T., Lee, S.T., Welch, K.D., Panter, K.E., Kem, W. 2011. Determination of the relative toxicity of enantiomers with cell-based assays. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. 100:581-7.
The physiological effects and toxicokinetics of tall larkspur (Delphinium barbeyi) alkaloids in cattle -
Green, B.T., Welch, K.D., Pfister, J.A., Cook, D., Stegelmeier, B.L., Lee, S.T., Gardner, D.R., Panter, K.E. 2011. The physiological effects and toxicokinetics of tall larkspur (Delphinium barbeyi) alkaloids in cattle. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. p. 557-65.
Acute toxicity of selenium compounds commonly found in selenium-accumulator plants -
Davis, T.Z., Stegelmeier, B.L., Green, B.T., Welch, K.D., Panter, K.E., Hall, J.O. 2011. Acute toxicity of selenium compounds commonly found in selenium-accumulator plants. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. 91:525-31.
The Actions of Piperidine Alkaloids at Fetal Muscle-Type and Autonomic-Type Nicotinic Acetylcholine Receptors Reprint Icon -
Green, B.T., Lee, S.T., Panter, K.E., Welch, K.D., Cook, D., Pfister, J.A., Kem, W.R. 2010. The Actions of Piperidine Alkaloids at Fetal Muscle-Type and Autonomic-Type Nicotinic Acetylcholine Receptors. Experimental Biology.
Plants teratogenic to livestock in the United States -
Panter, K.E., Welch, K.D., Lee, S.T., Gardner, D.R., Stegelmeier, B.L., Ralphs, M.H., Davis, T.Z., Green, B.T., Pfister, J.A., Cook, D. 2011. Plants teratogenic to livestock in the United States. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. 36:236-42.
Effect of MDL-Type alkaloids on tall larkspur toxicosis -
Dose-response evaluation of Veratrum californicum in sheep -
Welch, K.D., Lee, S.T., Gardner, D.R., Panter, K.E., Stegelmeier, B.L., Cook, D. 2011. Dose-Response evaluation of Veratrum californicum in sheep. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. 37:243-50.
Differences in ponderosa pine isocupressic acid concentrations across space and time -
Cook, D., Gardner, D.R., Pfister, J.A., Panter, K.E., Stegelmeier, B.L., Lee, S.T., Welch, K.D., Green, B.T., Davis, T.Z. 2010. Differences in ponderosa pine isocupressic acid concentrations across space and time. Rangelands. 32(2):14-7.
Actions of Piperidine Alkaloid Teratogens at Fetal Nicotinic Acetylcholine Receptors. Reprint Icon -
Green, B.T., Lee, S.T., Panter, K.E., Welch, K.D., Cook, D., Pfister, J.A., Kem, W.R. 2010. Actions of Piperidine Alkaloid Teratogens at Fetal Nicotinic Acetylcholine Receptors. Neurotoxicology and Teratology. 32:383-390. Published online at: http://dx.doi.org/10.1016/j.ntt.2010.01.011
The comparative pathology of locoweed poisoning in horses and other livestock -
Stegelmeier, B.L., Davis, T.Z., Welch, K.D., Green, B.T., Gardner, D.R., Lee, S.T., Ralphs, M.H., Pfister, J.A., Cook, D., Panter, K.E. 2011. The comparative pathology of locoweed poisoning in horses and other livestock. In: Riet-Correa, F., Pfister, J., Schild, A.L., Wierenga, T., editors. Poisoning by Plants, Mycotoxins, and Related Toxins. Cambridge, MA. CAB International. 48:309-10.
Swainsonine Concentrations and Endophyte Amounts of Undifilum oxytropis in Different Plant Parts of Oxytropis sericea Reprint Icon -
Cook, D., Gardner, D.R., Ralphs, M.H., Pfister, J.A., Welch, K.D., Green, B.T. 2009. Swainsonine Concentrations and Endophyte Amounts of Undifilum oxytropis in Different Plant Parts of Oxytropis sericea. Journal of Chemical Ecology, Vol. 35(10):1272-1278. (www.springerlink.com) DOI 0.1007/s10886-009-9710-9
Solutions to locoweed poisoning in New Mexico and the Western United States -
Graham, D., Creamer, R., Cook, D., Stegelmeier, B.L., Welch, K.D., Pfister, J.A., Panter, K.E., Cibils, A., Ralphs, M.H., Encinias, M., Mc Daniel, K., Thompson, D., Gardner, K. 2009. Solutions to locoweed poisoning in New Mexico and the Western United States. Rangelands. 31(6):3-8.
Quantitative PCR Method to Measure the Fungal Endopyte in Locoweeds Reprint Icon -
Cook, D., Gardner, D.R., Welch, K.D., Roper, J.M., Ralphs, M.H., Green, B.T. 2009. Quantitative PCR Method to Measure the Fungal Endopyte in Locoweeds. Journal of Agricultural and Food Chemistry. 57:6050-6054
Influence of 7, 8-methylenedioxylycoctonine-type Alkaloids on the Toxic Effects Associated with Ingestion of Tall Larkspurs (Delphinium spp.)in Cattle Reprint Icon -
Welch, K.D., Green, B.T., Gardner, D.R., Cook, D., Pfister, J.A., Stegelmeier, B.L., Panter, K.E., Davis, T.Z. 2010. Influence of 7, 8-methylenedioxylycoctonine-type Alkaloids on the Toxic Effects Associated with Ingestion of Tall Larkspurs (Delphinium spp.)in Cattle. American Journal of Veterinary Research. Vol 71, No 4, pp 487-492.
The Biogeographical Distribution of Duncecap Larkspur (Delphinium occidentale) Chemotypes and Their Potential Toxicity Reprint Icon -
Cook, D., Gardner, D.R., Pfister, J.A., Welch, K.D., Green, B.T., Lee, S.T. 2009. The Biogeographical Distribution of Duncecap Larkspur (Delphinium occidentale) Chemotypes and Their Potential Toxicity. Journal of Chemical Ecology 35:6443-652
Cyclopamine-induced Synophthalmia in Sheep: Defining a Critical Window and Toxicokinetic Evaluation Reprint Icon -
Welch, K.D., Panter, K.E., Lee, S.T., Gardner, D.R., Stegelmeier, B.L., Cook, D. 2009. Cyclopamine-induced Synophthalmia in Sheep: Defining a Critical Window and Toxicokinetic Evaluation. Journal of Applied Toxicology, 29:414-421. (www.interscience.wiley.com) DOI 10.1002/jat.1427
The Effect of Poisonous Range Plants on Abortions in Livestock Reprint Icon -
Welch, K.D., Davis, T.Z., Panter, K.E., Pfister, J.A., Green, B.T. 2009. The Effect of Poisonous Range Plants on Abortions in Livestock. Rangelands, 31(1):28-34. http://www.bioone.org/doi/pdf/10.2111/1551-501X-31.1.45?
Locoweed Poisoning in Cattle Reprint Icon -
Cook, D., Ralphs, M.H., Welch, K.D., Stegelmeier, B.L. 2009. Locoweed Poisoning in Cattle. Rangelands, 31(1):16-21. http://www.bioone.org/doi/pdf/10.2111/1551-501X-31.1.45?
Identifying Plant Poisoning in Livestock Reprint Icon -
Stegelmeier, B.L., Green, B.T., Panter, K.E., Welch, K.D., Hall, J.O. 2009. Identifying Plant Poisoning in Livestock. Rangelands 31(1):5-9 http://www.bioone.org/doi/pdf/10.2111/1551-501X-31.1.45?
Value of Plant Diversity for Diet Mixing and Sequencing in Herbivores Reprint Icon -
Provenza, F.D., Villalba, J.J., Wiedmeier, R.W., Layman, T., Owens, J., Lisonbee, L., Clemensen, A., Welch, K.D., Gardner, D.R., Lee, S.T. 2009. Value of Plant Diversity for Diet Mixing and Sequencing in Herbivores. Rangelands. 31(1):45-49. DOI:10.2111/1551-501X-31.1.45
Lupine Induced "Crooked Calf Disease": The Last 20 Years Reprint Icon -
Lee, S.T., Panter, K.E., Gay, C., Pfister, J.A., Ralphs, M.H., Gardner, D.R., Stegelmeier, B.L., Motteram, E., Cook, D., Welch, K.D., Green, B.T., Davis, T.Z. 2008. Lupine Induced "Crooked Calf Disease": The Last 20 Years. Rangelands. 30(6): 13-8.
The Alkaloid Profiles of Lupinus sulphureus Reprint Icon -
Cook, D., Lee, S.T., Gardner, D.R., Pfister, J.A., Welch, K.D., Green, B.T., Davis, T.Z., Panter, K.E. 2009. The Alkaloid Profiles of Lupinus sulphureus. Journal of Agriculture and Food Chemistry, 57(4):1646-1653.
Investigation of the Susceptibility of Various Strains of Mice to Methyllycaconitine Toxicosis Reprint Icon -
Welch, K.D., Green, B.T., Panter, K.E., Gardner, D.R., Pfister, J.A., Cook, D., Stegelmeier, B.L. 2009. Investigation of the Susceptibility of Various Strains of Mice to Methyllycaconitine Toxicosis. Journal of Animal Science, 87:1558-1564. doi:102527/jas.2008-1577
Serum Elimination Profiles of Methyllycaconitine and Deltaline in Cattle Following Oral Administration of Larkspur (Delphinium barbeyi) Reprint Icon -
Green, B.T., Welch, K.D., Gardner, D.R., Stegelmeier, B.L., Davis, T.Z., Cook, D., Lee, S.T., Pfister, J.A., Panter, K.E. 2009. Serum Elimination Profiles of Methyllycaconitine and Deltaline in Cattle Following Oral Administration of Larkspur (Delphinium barbeyi). American Journal of Veterinary Research, 70(7):926-931.
Steroselective Potencies and Relative Toxicities of Coniine Enantiomers -
Lee, S.T., Green, B.T., Welch, K.D., Pfister, J.A., Panter, K.E. 2008. Steroselective Potencies and Relative Toxicities of Coniine Enantiomers. Chemical Research in Toxicology. 21(10): 2061-2064. DOI 10.1021/tx800229w
Effect of body condition on consumption of pine needles (Pinus ponderosa) by beef cows -
Pfister, J.A., Panter, K.E., Gardner, D.R., Cook, D., Welch, K.D. 2008. Effect of body condition on consumption of pine needles (Pinus ponderosa) by beef cows. Journal of Animal Science. 86:3608-16. DOI: 10.2527/jas.2008-1000.
The effect of 7, 8-Methylenedioxylycoctonine -Type Diterpenoid Alkaloids on the Toxicity of Methyllycaconitine in Mice Reprint Icon -
Welch, K.D., Panter, K.E., Gardner, D.R., Green, B.T., Pfister, J.A., Cook, D., Stegelmeier, B.L. 2008. The effect of 7, 8-Methylenedioxylycoctonine -Type Diterpenoid Alkaloids on the Toxicity of Ethyllycaconitine in Mice. Journal of Animal Science, J. Anim. Sci. 86:2761-2770.
Effects of Larkspur (Delphinium barbeyi) on Heart Rate and Electrically Evoked Electromyographic Response of the External Anal Sphincter in Cattle. Reprint Icon -
Green, B.T., Pfister, J.A., Cook, D., Welch, K.D., Stegelmeier, B.L., Lee, S.T., Gardner, D.R., Knoppel, E.L., Panter, K.E. 2009. Effects of Larkspur (Delphinium barbeyi) on Heart Rate and Electrically Evoked Electromyographic Response of the External Anal Sphincter in Cattle. American Journal of Veterinary Research. 70(4):539-546
The effect of body condition on serum concentrations of two teratogenic alkaloids (anagyrine and ammodendrine) from Lupines (Lupinus spp.) that cause crooked calf disease. Reprint Icon -
Lee, S.T., Panter, K.E., Pfister, J.A., Gardner, D.R., Welch, K.D. 2008. The Effect of Body Condition on Serum Concentrations of Two Teratogenic Alkaloids (Anagyrine and Ammodendrine) From Lupines (Lupinus spp.) That Cause Crooked Calf Disease. Journal of Animal Science. 86:2771-2778 doi:10.2527/jas.2007-0610.
The Effect of High Deltaline Concentration on the Toxicity of Methyllycaconitine in Mice -
Welch, K.D., Panter, K.E., Gardner, D.R., Green, B.T., Pfister, J.A., Cook, D. 2008. The Effect of High Deltaline Concentration on the Toxicity of Methyllycaconitine in Mice. International Society on Toxicology Meeting.
Last Modified: 8/26/2016
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