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Michael P Heaton (Mike)
Research Microbiologist


Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Introgression and disruption of migration routes have shaped the genetic integrity of wildebeest populations - (Peer Reviewed Journal)
Liu, X., Lin, L., Sinding, M.S., Bertola, L.D., Hanghoj, K., Quinn, L., Garcia-Erill, G., Rasmussen, M.S., Schubert, M., Pecnerova, P., Balboa, R.F., Li, Z., Heaton, M.P., Smith, T.P.L., Pinto, R., Wang, X., Kuja, J., Bruniche-Olsen, A., Meisner, J., Santander, C.G., Ogutu, J.O., Masembe, C., da Fonseca, R.R., Muwanika, V., Siegismund, H.R., Albrechtsen, A., Moltke, I., Heller, R. 2024. Introgression and disruption of migration routes have shaped the genetic integrity of wildebeest populations. Nature Communications. 15. Article 2921. https://doi.org/10.1038/s41467-024-47015-y.
African bush pigs exhibit porous species boundaries and appeared in Madagascar concurrently with human arrival - (Peer Reviewed Journal)
Balboa, R.F., Bertola, L., Bruniche-Olsen, A., Rasmussen, M., Liu, X., Besnard, G., Salmona, J., Santander, C.G., He, S., Zinner, D., Heaton, M.P., Smith, T.P., Moltke, I., Albrechtsen, A., Heller, R. et al. 2024. African bush pigs exhibit porous species boundaries and appeared in Madagascar concurrently with human arrival. Nature Communications. 15. Article 172. https://doi.org/10.1038/s41467-023-44105-1.
African bush pigs exhibit porous species boundaries and appeared in Madagascar concurrently with human arrival - ()
Balboa, R.F., Bertola, L., Bruniche-Olsen, A., Rasmussen, M., Liu, X., Santander, C.G., He, S., Zinner, D., Heaton, M.P., Smith, T.P.L., Muwanika, V., Masembe, C., Schubert, M., Kuja, J., Quinn, L., Garcia-Erill, G., Lin, L., Wang, X., Moltke, I., Albrechtsen, A., Heller, R., et. al. 2023. African bush pigs exhibit porous species boundaries and appeared in Madagascar concurrently with human arrival. bioRxiv. https://doi.org/10.1101/2023.08.23.553838.
First gene-edited calf with reduced susceptibility to a major viral pathogen - (Peer Reviewed Journal)
Workman, A.M., Heaton, M.P., Vander Ley, B., Webster, D., Sherry, L., Bostrom, J.R., Larson, S., Kalbfleisch, T., Harhay, G.P., Jobman, E., Carlson, D., Sonstegard, T.S. 2023. First gene-edited calf with reduced susceptibility to a major viral pathogen. Proceedings of the National Academy of Sciences-Nexus. 2(5). Article pgad125. https://doi.org/10.1093/pnasnexus/pgad125.
A CD46-edited calf with reduced susceptibility to bovine viral diarrhea virus - (Abstract Only)
Colonialism in Southern Africa leaves a lasting legacy of reduced genetic diversity in Cape buffalo - (Peer Reviewed Journal)
Quinn, L., Garcia-Erill, G., Santander, C., Bruniche-Olsen, A., Liu, X., Sinding, M.S., Heaton, M.P., Smith, T.P.L., Pecnerova, P., Bertola, L.D., Hanghoj, K., Rasmussen, M.S., De Jager, D., Siegismund, H.R., Albrechtsen, A., Heller, R., Moltke, I. 2023. Colonialism in Southern Africa leaves a lasting legacy of reduced genetic diversity in Cape buffalo. Molecular Ecology. Article 16851. https://doi.org/10.1111/mec.16851.
Genetic diversity and connectivity of moose (Alces americanus americanus) in eastern North America - (Peer Reviewed Journal)
Rosenblatt, E., Gieder, K., Donovan, T., Murdoch, J., Smith, T.P.L., Heaton, M.P., Kalbfleisch, T.S., Murdoch, B.M., Bhattarai, S., Pacht, E., Verbist, E., Basnayake, V., McKay, S. 2023. Genetic diversity and connectivity of moose (Alces americanus americanus) in eastern North America. Conservation Genetics. 24:235-248. https://doi.org/10.1007/s10592-022-01496-w.
First gene-edited calf with reduced susceptibility to a major viral pathogen - ()
Workman, A.M., Heaton, M.P., Vander Ley, B.L., Webster, D.A., Sherry, L., Larson, S., Kalbfleisch, T.S., Harhay, G.P., Jobman, E.E., Carlson, D.F., Sonstegard, T.S. 2022. First gene-edited calf with reduced susceptibility to a major viral pathogen. bioRxiv. Article 519336. https://doi.org/10.1101/2022.12.08.519336.
Impact of four ovine TMEM154 haplotypes on ewes during multiyear lentivirus exposure - (Peer Reviewed Journal)
Freking, B.A., Murphy, T.W., Chitko-McKown, C.G., Workman, A.M., Heaton, M.P. 2022. Impact of four ovine TMEM154 haplotypes on ewes during multiyear lentivirus exposure. International Journal of Molecular Sciences. 23(23). Article 14966. https://doi.org/10.3390/ijms232314966.
Using whole genome sequence to compare variant callers and breed differences of US sheep - (Peer Reviewed Journal)
Stegemiller, M.R., Redden, R.R., Notter, D.R., Taylor, T., Taylor, J.B., Cockett, N.E., Heaton, M.P., Kalbfleisch, T.S., Murdoch, B.M. 2023. Using whole genome sequence to compare variant callers and breed differences of US sheep. Frontiers in Genetics. 13. Article 1060882. https://doi.org/10.3389/fgene.2022.1060882.
Table 1. Genome sequence context for JMJD1C SNPs associated with bovine congestive heart failure (BCHF) - ()
Heaton, M., Harhay, G., Smith, T.P.L., Kuhn, K., Kalbfleisch, T.S., Jobman, E., Vander Ley, B. 2022. Table 1. Genome sequence context for JMJD1C SNPs associated with bovine congestive heart failure (BCHF). Figshare. Dataset. https://doi.org/10.6084/m9.figshare.19780558.v1.
Structural variant-based pangenome construction has low sensitivity to variability of haplotype-resolved bovine assemblies - (Peer Reviewed Journal)
Leonard, A.S., Crysnanto, D., Fang, Z., Heaton, M.P., Vander Ley, B.L., Herrera, C., Bollwein, H., Bickhart, D.M., Kuhn, K.L., Smith, T.P.L., Rosen, B.D., Pausch, H. 2022. Structural variant-based pangenome construction has low sensitivity to variability of haplotype-resolved bovine assemblies. Nature Communications. 13. Article 3012. https://doi.org/10.1038/s41467-022-30680-2.
Gaur genome reveals expansion of sperm odorant receptors in domesticated cattle - (Peer Reviewed Journal)
Low, W.Y., Rosen, B.D., Ren, Y., Bickhart, D.M., To, T., Martin, F.J., Billis, K., Sonstegard, T.S., Sullivan, S.T., Hiendleder, S., Williams, J.L., Heaton, M.P., Smith, T.P. 2022. Gaur genome reveals expansion of sperm odorant receptors in domesticated cattle. BMC Genomics. 23. Article 344. https://doi.org/10.1186/s12864-022-08561-1.
Association of ARRDC3 and NFIA variants with bovine congestive heart failure in feedlot cattle - (Peer Reviewed Journal)
Heaton, M.P., Harhay, G.P., Bassett, A.S., Clark, H.J., Carlson, J.M., Jobman, E.E., Sadd, H.R., Pelster, M.C., Workman, A.M., Kuehn, L.A., Kalbfleisch, T.S., Piscatelli, H., Carrie, M., Krafsur, G.M., Grotelueschen, D.M., Vander Ley, B.L. 2022. Association of ARRDC3 and NFIA variants with bovine congestive heart failure in feedlot cattle. F1000Research. 11. Article 385. https://doi.org/10.12688/f1000research.109488.1 .
An improved ovine reference genome assembly to facilitate in depth functional annotation of the sheep genome - (Peer Reviewed Journal)
Davenport, K.M., Bickhart, D.M., Worley, K.C., Murali, S.C., Salavati, M., Clark, E.L., Cockett, N., Heaton, M.P., Smith, T.P., Murdoch, B.M., Rosen, B.D. 2022. An improved ovine reference genome assembly to facilitate in depth functional annotation of the sheep genome. Gigascience. 11. Article giab096. https://doi.org/10.1093/gigascience/giab096.
Evaluating large spontaneous deletions in a bovine cell line selected for bovine viral diarrhea virus resistance - (Peer Reviewed Journal)
Workman, A.M., Heaton, M.P., Webster, D.A., Harhay, G.P., Kalbfleisch, T.S., Smith, T.P.L., Falkenberg, S.M., Carlson, D.F., Sonstegard, T.S. 2021. Evaluating large spontaneous deletions in a bovine cell line selected for bovine viral diarrhea virus resistance. Viruses. 13(11). Article 2147. https://doi.org/10.3390/v13112147.
Effect of TMEM154 E35K variant (haplotypes 1 and 3) on the incidence of ovine lentivirus infection and ewe productivity during lifetime exposure - (Peer Reviewed Journal)
Murphy, T.W., Chitko-McKown, C.G., Heaton, M.P., Freking, B.A. 2021. Effect of TMEM154 E35K variant (haplotypes 1 and 3) on the incidence of ovine lentivirus infection and ewe productivity during lifetime exposure. Journal of Animal Science. 99(11). Article skab304. https://doi.org/10.1093/jas/skab304.
Classification of small ruminant lentivirus subtype A2, subgroups 1 and 2 based on whole genome comparisons and complex recombination patterns [version 2; revised] - (Peer Reviewed Journal)
Association of TLR2 haplotypes encoding Q650 with reduced susceptibility to ovine Johne’s disease in Turkish sheep - (Peer Reviewed Journal)
Yaman, Y., Aymaz, R., Keles, M., Bay, V., Ün, C., Heaton, M.P. 2021. Association of TLR2 haplotypes encoding Q650 with reduced susceptibility to ovine Johne’s disease in Turkish sheep. Scientific Reports. 11. Article 7088. https://doi.org/10.1038/s41598-021-86605-4.
Evaluation of CD109, PCP4, and SEMA3D genes for their association with Ovine Johne’s disease in Turkish sheep - (Peer Reviewed Journal)
Yaman, Y., Aymaz, R., Keles, M., Bay, V., Hatipoglu, E., Kaptan, C., Baskurt, A., Yilmaz, O., Heaton, M.P. 2021. Evaluation of CD109, PCP4, and SEMA3D genes for their association with Ovine Johne’s disease in Turkish sheep. Animal Biotechnology. Article 1887880. https://doi.org/10.1080/10495398.2021.1887880.
Association of TLR2 haplotypes encoding Q650 with reduced susceptibility to ovine Johne’s disease in Turkish sheep - ()
Yaman, Y., Aymaz, R., Keles, M., Bay, V., Ün, C., Heaton, M.P. 2021. Association of TLR2 haplotypes encoding Q650 with reduced susceptibility to ovine Johne’s disease in Turkish sheep. Research Square. pg. 1-17. https://doi.org/10.21203/rs.3.rs-146053/v1.
A reference genome assembly of American bison, Bison bison bison - (Peer Reviewed Journal)
Oppenheimer, J., Rosen, B.D., Heaton, M.P., Vander Ley, B.L., Shafer, W.R., Schuetze, F.T., Stroud, B., Kuehn, L.A., McClure, J.C., Barfield, J.P., Blackburn, H.D., Kalbfleisch, T.S., Bickhart, D.M., Davenport, K.M., Kuhn, K.L., Green, R.E., Shapiro, B., Smith, T.P.L. 2021. A reference genome assembly of American bison, Bison bison bison. Journal of Heredity. 112(2):174-183. https://doi.org/10.1093/jhered/esab003.
A reference genome assembly of Simmental cattle, Bos taurus taurus - (Peer Reviewed Journal)
Heaton, M.P., Smith, T.P.L., Bickhart, D.M., Vander Ley, B.L., Kuehn, L.A., Oppenheimer, J., Shafer, W.R., Schuetze, F.T., Stroud, B., McClure, J.C., Barfield, J.P., Blackburn, H.D., Kalbfleisch, T.S., Davenport, K.M., Kuhn, K.L., Green, R.E., Shapiro, B., Rosen, B.D. 2021. A reference genome assembly of Simmental cattle, Bos taurus taurus. Journal of Heredity. 112(2):184-191. https://doi.org/10.1093/jhered/esab002.
Classification of small ruminant lentivirus subtype A2, subgroups 1 and 2 based on whole genome comparisons and complex recombination patterns - ()
Dickey, A.M., Smith, T.P.L., Clawson, M.L., Heaton, M.P., Workman, A.M. 2020. Classification of small ruminant lentivirus subtype A2, subgroups 1 and 2 based on whole genome comparisons and complex recombination patterns. F1000Research. 9:1449. https://doi.org/10.12688/f1000research.27898.1.
Using triallelic SNPs for determining parentage in North American yak (Bos grunniens) and estimating cattle (B. taurus) introgression - (Peer Reviewed Journal)
Kalbfleisch, T., Petersen, J.L., Tait, R.G., Qiu, J., Basnayake, V., Hackett, P.H., Heaton, M.P. 2020. Using triallelic SNPs for determining parentage in North American yak (Bos grunniens) and estimating cattle (B. taurus) introgression. F1000Research. 9:1096. https://doi.org/10.12688/f1000research.25803.1.
Reassembly of cattle immune gene clusters for quantitative analysis - (Abstract Only)
Resistance to bovine viral diarrhea virus (BVDV) infection in the bovine kidney CRIB cell line is not due to PTPN12, GRID2, or RABGAP1L mutations - (Abstract Only)
Workman, A.M., Heaton, M.P., Webster, D.A., Kalbfleisch, T.S., Smith, T.P., Carlson, D.F., Sonstegard, T.S. 2020. Resistance to bovine viral diarrhea virus (BVDV) infection in the bovine kidney CRIB cell line is not due to PTPN12, GRID2, or RABGAP1L mutations [abstract]. In: Proceedings of American Society for Virology Meeting, June 13-17, 2020, Fort Collins, Colorado. Poster No. P37-1.
Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle - (Peer Reviewed Journal)
Low, W., Tearle, R., Liu, C., Koren, S., Rhie, A., Bickhart, D.M., Rosen, B.D., Kronenberg, Z.N., Kingan, S.B., Tseng, E., Thibaud-Nissen, F., Martin, F., Billis, K., Ghurye, J., Hastie, A.R., Lee, J., Pang, A., Heaton, M.P., Phillippy, A.M., Hiendleder, S., Smith, T.P., Williams, J.L. 2020. Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle. Nature Communications. 11:2071. https://doi.org/10.1038/s41467-020-15848-y.
Continuous chromosome-scale haplotypes assembled from a single interspecies F1 hybrid of yak and cattle - (Peer Reviewed Journal)
Rice, E.S., Koren, S., Rhie, A., Heaton, M.P., Kalbfleisch, T., Hardy, T., Hackett, P., Bickhart, D.M., Rosen, B.D., Vander Ley, B., Maurer, N.W., Green, R.E., Phillippy, A.M., Petersen, J.L., Smith, T.P. 2020. Continuous chromosome-scale haplotypes assembled from a single interspecies F1 hybrid of yak and cattle. GigaScience. 9(4):1-9. https://doi.org/10.1093/gigascience/giaa029.
Detection of bovine viral diarrhea virus in stable flies following consumption of blood from persistently infected cattle - (Peer Reviewed Journal)
Carlson, J.M., Vander Ley, B.L., Lee, S.I., Grotelueschen, D.M., Walz, P.H., Workman, A.M., Heaton, M.P., Boxler, D.J. 2020. Detection of bovine viral diarrhea virus in stable flies following consumption of blood from persistently infected cattle. Journal of Veterinary Diagnostic Investigation. 32(1):108-111. https://doi.org/10.1177/1040638719898688.
Association of ARRDC3 and NF1A genes with bovine congestive heart failure - (Abstract Only)
Heaton, M.P., Harhay, G.P., Bassett, A.S., Clark, H.J., Carlson, J.M., Smith, H.R., Pelster, M.C., Workman, A.M., Grotelueschen, D.M., Vander Ley, B.L. 2020. Association of ARRDC3 and NF1A genes with bovine congestive heart failure. In: Plant and Animal Genome Conference Proceedings, January 11-15, 2020, San Diego, California. PE0326.
Progress report on a plains bison-Simmental interspecies cross for genome assembly by trio binning - ()
Heaton, M.P., Kuehn, L.A., Vander Ley, B.L., Clark, H.J., Shafer, W., Schuetze, F., Stroud, B., Barfield, J.P., Blackburn, H.D., Kalbfleisch, T.S., Rosen, B.D., Bickhart, D.M., Oppenheimer, J., Shapiro, B., Green, R.E., Smith, T.P. 2019. Progress report on a plains bison-Simmental interspecies cross for genome assembly by trio binning [abstract]. Fall Focus 2019, Manhattan, Kansas, August 25-27, 2019. Available: https://simmental.org.
Chromosome-length haplotigs for yak and cattle from trio binning assembly of an F1 hybrid - ()
Rice, E.S., Koren, S., Rhie, A., Heaton, M.P., Kalbfleisch, T.S., Hardy, T., Hackett, P.H., Bickhart, D.M., Rosen, B.D., Vander Ley, B., Maurer, N.W., Green, R.E., Phillippy, A.M., Petersen, J.L., Smith, T.P.L. 2019. Chromosome-length haplotigs for yak and cattle from trio binning assembly of an F1 hybrid. bioRxiv. 737171. https://doi.org/10.1101/737171.
Evaluation of EPAS1 variants for association with bovine congestive heart failure - (Peer Reviewed Journal)
Heaton, M.P., Bassett, A.S., Whitman, K.J., Krafsur, G.M., Lee, S., Carlson, J.M., Clark, H.J., Smith, H.R., Pelster, M.C., Basnayake, V., Grotelueschen, D.M., Vander Ley, B.L. 2019. Evaluation of EPAS1 variants for association with bovine congestive heart failure. F1000Research. 8:1189. https://doi.org/10.12688/f1000research.19951.1.
Association of TMEM154 variants with visna/maedi virus infection in Turkish sheep - (Peer Reviewed Journal)
Yaman, Y., Keles, M., Aymaz, R., Sevim, S., Sezenler, T., Onaldi, A.T., Kaptan, C., Baskurt, A., Koncagul, S., Oner, Y., Ozturk, E., Iriadam, M., Un, C., Heaton, M.P. 2019. Association of TMEM154 variants with visna/maedi virus infection in Turkish sheep. Small Ruminant Research. 177:61-67. https://doi.org/10.1016/j.smallrumres.2019.06.006.
Impact of CD46 knockout on bovine viral diarrhea virus (BVDV) replication in Madin-Darby bovine kidney cells - (Abstract Only)
Workman, A.M., Webster, D.A., Carlson, D.F., Heaton, M.P., Falkenberg, S.M., Neill, J.D., Sonstegard, T.S. 2019. Impact of CD46 knockout on bovine viral diarrhea virus (BVDV) replication in Madin-Darby bovine kidney cells [abstract]. In: Proceedings of American Society for Virology Meeting, July 20-24, 2019, Minneapolis, Minnesota. Poster No. P17-16.
A bovine CD18 signal peptide variant with increased binding activity to Mannheimia hemolytica leukotoxin - (Peer Reviewed Journal)
Workman, A.M., Chitko-McKown, C.G., Smith, T.P.L., Bennett, G.L., Kalbfleisch, T.S., Basnayake, V., Heaton, M.P. 2018. A bovine CD18 signal peptide variant with increased binding activity to Mannheimia hemolytica leukotoxin. F1000Research. 7:1985. https://doi.org/10.12688/f1000research.17187.1.
Evaluation of EPAS1 variants for association with bovine congestive heart failure - (Abstract Only)
Heaton, M.P., Bassett, A.S., Whitman, K.J., Krafsur, G.M., Lee, S.I., Carlson, J.M., Clark, H.J., Smith, H.R., Pelster, M.C., Basnayake, V., Grotelueschen, D.M., Vander Ley, B.L. 2019. Evaluation of EPAS1 variants for association with bovine congestive heart failure [abstract]. International Plant & Animal Genome XXVII Conference, January 12-16, 2019, San Diego, California. Abstract PO0365. Available: https://plan.core-apps.com/pag_2019/abstracts
First complete genome sequence of a genotype A2, subgroup 4 small ruminant lentivirus - (Peer Reviewed Journal)
Workman, A.M., Clawson, M.L., Heaton, M.P., Dickey, A.M. 2018. First complete genome sequence of a genotype A2, subgroup 4 small ruminant lentivirus. MICROBIOLOGY RESOURCE ANNOUNCEMENTS. 7(19):e01337-18. https://doi.org/10.1128/MRA.01337-18.
Structure-guided identification of a nonhuman morbillivirus with zoonotic potential - (Peer Reviewed Journal)
Abdullah, N., Kelly, J.T., Graham, S.C., Birch, J., Goncalves-Carneiro, D., Mitchell, T., Thompson, R.N., Lythgoe, K.A., Logan, N., Hosie, M.J., Bavro, V.N., Willett, B.J., Heaton, M.P., Bailey, D. 2018. Structure-guided identification of a nonhuman morbillivirus with zoonotic potential. Journal of Virology. 92(23):e01248-18. https://doi.org/10.1128/jvi.01248-18.
In search of a genetic cause for heart failure in beef cattle - (Abstract Only)
Heaton, M.P. 2018. In search of a genetic cause for heart failure in beef cattle. [abstract online]. Available: http://www.vbms.unl.edu.
Cardiopulmonary remodeling in fattened beef cattle: A naturally occurring large animal model of obesity-associated pulmonary hypertension with left heart disease - (Peer Reviewed Journal)
Krafsur, G.M., Neary, J.M., Garry, F., Holt, T., Gould, D.H., Mason, G.L., Thomas, M.G., Enns, R.M., Tuder, R.M., Heaton, M.P., Brown, R.D., Stenmark, K.R. 2019. Cardiopulmonary remodeling in fattened beef cattle: A naturally occurring large animal model of obesity-associated pulmonary hypertension with left heart disease. Pulmonary Circulation. 9(1):1-13. https://doi.org/10.1177/2045894018796804.
A SNP resource for studying North American moose - (Peer Reviewed Journal)
Kalbfleisch, T.S., Murdoch, B.M., Smith, T.P.L., Murdoch, J.D., Heaton, M.P., Mckay, S.D. 2018. A SNP resource for studying North American moose. F1000Research. 7(40):1-17. https://doi.org/10.12688/f1000research.13501.1.
Using cattle and sheep reference assemblies to develop genomic resources for North American moose - (Abstract Only)
Heaton, M.P. 2018. Using cattle and sheep reference assemblies to develop genomic resources for North American moose [abstract]. International Plant & Animal Genome XXVI Conference, January 13-17, 2018, San Diego, California. Abstract W153. Available: https://plan.core-apps.com/pag_2018/abstracts
Development and characterization of a bovine monocyte-derived macrophage cell line - (Abstract Only)
Chitko-Mckown, C.G., Bartens, M.C., Gibson, A.J., Holder, A., Vats, A., Brown, E., Kolakowski, J., Workman, A.M., Heaton, M.P., Kalbfleisch, T.S., Werling, D. 2021. Development and characterization of a bovine monocyte-derived macrophage cell line [abstract]. Conference of Research Workers in Animal Diseases Conference, December 3-5,2017, Chicago, Illinois. Abstract #141. Available: https://crwad.org/proceedings-archive/
Using sheep genomes from diverse U.S. breeds to identify missense variants in genes affecting fecundity Reprint Icon - (Peer Reviewed Journal)
Heaton, M.P., Smith, T.P.L., Freking, B.A., Workman, A.M., Bennett, G.L., Carnahan, J.K., Kalbfleisch, T.S. 2017. Using sheep genomes from diverse U.S. breeds to identify missense variants in genes affecting fecundity. F1000Research. 6:1303. https://doi.org/10.12688/f1000research.12216.1.
Effects of maternal lines and mating systems on lamb carcass merit - (Abstract Only)
Wall, K., King, D.A., Wheeler, T.L., Kerth, C., Bennett, G.L., Heaton, M.P., Leymaster, K., Shackelford, S.D. 2017. Effects of maternal lines and mating systems on lamb carcass merit. [Abstract]. American Meat Science Association Conference Reciprocal Proceedings. June 18-21, 2017, College Station, Texas. No 24.
Closed genomes and phenotypes of seven Histophilus somni isolates from beef calves with bovine respiratory disease complex - (Abstract Only)
Harhay, G.P., Harhay, D.M., Bono, J.L., Smith, T.P., Heaton, M.P., Clawson, M.L., Chitko-McKown, C.G., Capik, S.F., DeDonder, K.D., Apley, M.D., Lubbers, B.V., White, B.J., Larson, R.L. 2017. Closed genomes and phenotypes of seven Histophilus somni isolates from beef calves with bovine respiratory disease complex [Abstract]. American Society for Microbiology Microbe Meeting, June 1-5, 2017, New Orleans, LA. Poster #Sunday-869.
Complete genome sequences of two genotype A2 small ruminant lentiviruses isolated from infected U.S. sheep - (Peer Reviewed Journal)
Workman, A.M., Dickey, A.M., Heaton, M.P., Clawson, M.L., Smith, T.P.L. 2017. Complete genome sequences of two genotype A2 small ruminant lentiviruses isolated from infected U.S. sheep. Genome Announcements. 5(13):e00109-17.
Using an online genome resource to identify myostatin variation in U.S. sheep - (Abstract Only)
Heaton, M.P., Smith, T.P., Kalbfleisch, T.S. 2017. Using an online genome resource to identify myostatin variation in U.S. sheep [abstract]. International Plant & Animal Genome XXV Conference, January 14-18, 2017, San Diego, CA. Poster #P1147.
Triallelic SNPs for estimating cattle introgression, inbreeding, and determining parentage in North American yak - (Abstract Only)
Kalbfleisch, T.S., Petersen, J.L., Hackett, P., Basnayake, V., Qiu, J., Simpson, E.B., Heaton, M.P. 2017. Triallelic SNPs for estimating cattle introgression, inbreeding, and determining parentage in North American Yak [abstract]. International Plant & Animal Genome XXV Conference, January 14-18, 2017, San Diego, CA. Poster #P0111.
Genomic signatures of Mannheimia haemolytica that associate with the lungs of cattle with respiratory disease, an integrative conjugative element, and antibiotic resistance genes - (Peer Reviewed Journal)
Clawson, M.L., Murray, R.W., Sweeney, M.T., Apley, M.D., DeDonder, K.D., Capik, S.F., Larson, R.L., Lubbers, B.V., White, B.J., Kalbfleisch, T.S., Schuller, G., Dickey, A.M., Harhay, G.P., Heaton, M.P., Chitko-McKown, C.G., Brichta-Harhay, D.M., Bono, J.L., Smith, T.P.L. 2016. Genomic signatures of Mannheimia haemolytica that associate with the lungs of cattle with respiratory disease, an integrative conjugative element, and antibiotic resistance genes. BMC Genomics. 17:982. doi: 10.1186/s12864-016-3316-8.
Using diverse U.S. beef cattle genomes to identify missense mutations in EPAS1, a gene associated with pulmonary hypertension - (Peer Reviewed Journal)
Heaton, M.P., Smith, T.P.L., Carnahan, J.K., Basnayake, V., Qiu, J., Simpson, B., Kalbfleisch, T.S. 2016. Using diverse U.S. beef cattle genomes to identify missense mutations in EPAS1, a gene associated with pulmonary hypertension. F1000Research. 5:2003. doi:10.12688/f1000research.9254.2.
Using diverse U.S. beef cattle genomes to identify missense mutations in EPAS1, a gene associated with high-altitude pulmonary hypertension - (Abstract Only)
Heaton, M.P., Smith, T.P.L., Carnahan, J.K., Basnayake, V., Qiu, J., Simpson, B., Kalbfleisch, T.S. 2016. Using diverse U.S. beef cattle genomes to identify missense mutations in EPAS1, a gene associated with high-altitude pulmonary hypertension [abstract]. 35th International Society for Animal Genetics (ISAG), July 23-27, 2016, Salt Lake City, UT. Poster #P6026.
Identification of the pan and core genomes for Mannheimia haemolytica genotypes 1 and 2 - (Abstract Only)
Clawson, M.L., Schuller, G., Dickey, A.M., Bono, J.L., Murray, R.W., Sweeney, M.T., Apley, M.D., DeDonder, K.D., Capik, S.F., Larson, R.L., Lubbers, B.V., White, B.J., Harhay, G.P., Heaton, M.P., Chitko-McKown, C.G., Harhay, D.M., Smith, T.P. 2016. Identification of the pan and core genomes for Mannheimia haemolytica genotypes 1 and 2. American Society for Microbiology 2016 Meeting, July 16-20, 2016, Boston, MA. Poster No. Friday-060.
Genome sequencing, metabolic and antibiotic resistance phenotyping of diverse nasopharyngeal bacteria isolated from cattle in an epidemiological study of bovine respiratory disease - (Abstract Only)
Harhay, G.P., Harhay, D.M., Bono, J.L., Smith, T.P., Heaton, M.P., Clawson, M.L., Chitko-McKown, C.G., Capik, S.F., DeDonder, K.D., Apley, M.D., Lubbers, B.V., White, B.J., Larson, R.L. 2016. Genome sequencing, metabolic and antibiotic resistance phenotyping of diverse nasopharyngeal bacteria isolated from cattle in an epidemiological study of bovine respiratory disease [abstract]. American Society for Microbiology 2016 Meeting, July 16-20, 2016, Boston, MA. Poster No. Friday-057.
Resolving bovine viral diarrhea virus subtypes from persistently infected US beef calves with complete genome sequence - (Peer Reviewed Journal)
Workman, A.M., Heaton, M.P., Harhay, G.P., Smith, T.P.L., Grotelueschen, D.M., Sjeklocha, D.B., Brodersen, B.W., Petersen, J.L., Chitko-McKown, C.G. 2016. Resolving bovine viral diarrhea virus subtypes from persistently infected U.S. beef calves with complete genome sequence. Journal of Veterinary Diagnostic Investigation. 28(5):519-528.
Identification of conserved genomic regions and variation therein amongst Cetartiodactyla species using next generation sequencing - (Abstract Only)
De Silva, K., Heaton, M.P., Kalbfleisch, T.S. 2016. Identification of conserved genomic regions and variation therein amongst Cetartiodactyla species using next generation sequencing. UT-KBRIN Bioinformatics Summit 2016, April 8-10, 2016, Lake Barkley State Resort Park, Cadiz, KY. Poster #16.
Whole genome sequences of the USMARC sheep diversity panel v 2.4 aligned to the ovine reference genome assembly - ()
Heaton, M.P., Smith, T.P., Kalbfleisch, T.S. 2016. Whole genome sequences of the USMARC sheep diversity panel v 2.4 aligned to the ovine reference genome assembly. Internet Web Page. www.ars.usda.gov/Services/Docs.htm?docid=25585 and www.ars.usda.gov/Research/docs.htm?docid=25589.
A searchable, whole genome resource designed for protein variant analysis in diverse lineages of U.S. beef cattle - (Abstract Only)
Heaton, M.P., Kalbfleisch, T.S., Carnahan, J.K., Smith, T.P.L., Harhay, G.P., Simpson, B., Qiu, J. 2015. A searchable, whole genome resource designed for protein variant analysis in diverse lineages of U.S. beef cattle [abstract]. International Plant and Animal Genome XXIV Conference Proceedings, January 9-13, 2016, San Diego, CA. Poster #P0506.
Whole genome sequences of the USMARC beef cattle diversity panel v2.9 aligned to the bovine reference genome assembly - ()
Heaton, M.P., Smith, T.P., Kalbfleisch, T.S. 2015. Whole genome sequences of the USMARC beef cattle diversity panel v2.9 aligned to the bovine reference genome assembly. Internet Web Page. www.ars.usda.gov/Services/Docs.htm?docid=25585 and www.ars.usda.gov/Research/docs.htm?docid=25586.
Full-length coding sequence for 12 bovine viral diarrhea virus isolates from persistently infected cattle in a feedyard in Kansas - (Peer Reviewed Journal)
Workman, A.M., Harhay, G.P., Heaton, M.P., Grotelueschen, D.M., Sjeklocha, D.B., Smith, T.P.L. 2015. Full-length coding sequence for 12 bovine viral diarrhea virus isolates from persistently infected cattle in a feedyard in Kansas. Genome Announcements. 3(3):e00487-15. doi:10.1128/genomeA.00487-15.
Complete closed genome sequences of a Mannheimia haemolytica serotype A1 leukotoxin deletion mutant and its wild type parent strain - (Peer Reviewed Journal)
Heaton, M.P., Harhay, G.P., Smith, T.P.L., Bono, J.L., Chitko-McKown, C.G. 2015. Complete closed genome sequences of a Mannheimia haemolytica serotype A1 leukotoxin deletion mutant and its wild-type parent strain. Genome Announcements. 3(3):e00417-15. DOI: 10.1128/genomeA.00417-15.
Identification of a mannheimia haemolytica genetic subtype that causes bovine respiratory disease - (Abstract Only)
Clawson, M.L., Murray, R.W., Sweeney, M.T., Apley, M.D., DeDonder, K.D., Capik, S., Larson, R., Lubbers, B.V., Kalbfleisch, T.S., Schuller, G., Harhay, G.P., Heaton, M.P., Chitko-McKown, C.G., Workman, A.M., Harhay, D.M., Bono, J.L., Smith, T.P.L. [abstract]. 2015. Identification of a mannheimia haemolytica genetic subtype that causes bovine respiratory disease. American Society for Microbiology 2015, 115th General Meeting, May 30-June 2, 2015, New Orleans, LA. Poster #1410.
Effects of maternal lines and mating systems on susceptibility to parasitism in a pasture-lambing, low-input production system - (Abstract Only)
Jones, S., Chase, C.C., Heaton, M.P., Shuck, K.K., Leymaster, K.A., Keele, J.W. 2015. Effects of maternal lines and mating systems on susceptibility to parasitism in a pasture-lambing, low-input production system. [abstract] Joint Abstracts of the American Dairy Science and Society of Animal Science. Journal of Animal Science 93 (Supplement s3):786-787.
Design of a DNA panel for genomic studies in Russian cattle breeds - (Peer Reviewed Journal)
Yudin, N.S., Vasil'Eva, L.A., Belyavskaya, V.A., Aitnazarov, R.B., Smirnov, P.N., Heaton, M.P., Laegreid, W.W., Orlowa, G.V., Romashenko, A.G., Voevoda, M.I. 2015. Design of a DNA panel for genomic studies in Russian cattle breeds. Russian Journal of Genetics: Applied Research. 5(1):21-25.
Genetic subgroup of small ruminant lentiviruses that infects sheep homozygous for TMEM154 frameshift deletion mutation A4delta53 - (Peer Reviewed Journal)
Clawson, M.L., Redden, R., Schuller, G., Heaton, M.P., Workman, A.M., Chitko-McKown, C.G., Smith, T.P.L., Leymaster, K.A. 2015. Genetic subgroup of small ruminant lentiviruses that infects sheep homozygous for TMEM154 frameshift deletion mutation A4delta53. Veterinary Research. 46:22.
Incidence of infection in 39-month-old ewes with TMEM154 diplotypes "1 1," "1 3," and "3 3" after natural exposure to ovine progressive pneumonia virus Reprint Icon - (Peer Reviewed Journal)
Leymaster, K.A., Chitko-McKown, C.G., Heaton, M.P. 2015. Incidence of infection in 39-month-old ewes with TMEM154 diplotypes "1 1," "1 3," and "3 3" after natural exposure to ovine progressive pneumonia virus. Journal of Animal Science. 93(1):41-45.
Association of TMEM154 missense mutations with lentiviral infection and virus subtypes in sheep - (Proceedings)
Heaton, M.P., Leymaster, K.A., Clawson, M.L. 2014. Association of TMEM154 missense mutations with lentiviral infection and virus subtypes in sheep. In: Proceedings of the 10th World Congress of Genetics Applied to Livestock Production, August 17-22, 2014, Vancouver, BC, Canada. Available. Paper No. 352. https://asas.org/wcgalp-proceedings
SNPs for parentage testing and traceability in globally diverse breeds of sheep - (Peer Reviewed Journal)
Heaton, M.P., Leymaster, K.A., Kalbfleisch, T.S., Kijas, J.W., Clarke, S.M., McEwan, J., Maddox, J.F., Basnayake, V., Petrik, D.T., Simpson, B., Smith, T.P., Chitko-McKown, C.G. 2014. SNPs for parentage testing and traceability in globally diverse breeds of sheep. PLoS One. 9(4):e94851. DOI: 10.1371/JOURNAL.PONE.0094851.
Sequencing a North American yak genome - ()
Heaton, M.P. 2014. Sequencing a North American yak genome. International Yak Association. Online available. IYAK.org. http://0101.nccdn.net/1_5/11e/372/14c/HeatonIYAK2014_ARSapproved.pdf.
Worldwide patterns of ancestry, divergence, and admixture in domesticated cattle - (Peer Reviewed Journal)
Decker, J.E., Mckay, S.D., Rolf, M.M., Kim, J., Alcala, A., Sonstegard, T.S., Hanotte, O., Gotherstrom, A., Seabury, C.M., Praharani, L., Babar, M., Regitano, L. ., Yildiz, M., Heaton, M.P., Lui, W., Lei, C., Reecy, J.M., Saif-Ur-Rehman, M., Schnabel, R.D., Taylor, J.F. 2014. Worldwide patterns of ancestry, divergence, and admixture in domesticated cattle. PLoS Genetics. 10(3):e1004254.
Complete closed genome sequences of four Mannheimia varigena isolates from cattle with shipping fever - (Peer Reviewed Journal)
Harhay, G.P., Murray, R.W., Lubbers, B., Griffin, D., Koren, S., Phillippy, A.M., Harhay, D.M., Bono, J.L., Clawson, M.L., Heaton, M.P., Chitko-McKown, C.G., Smith, T.P. 2014. Complete closed genome sequences of four Mannheimia varigena isolates from cattle with shipping fever. Genome Announcements. 2(1):e00088-14.
Complete closed genome sequences of three Bibersteinia trehalosi nasopharyngeal isolates from cattle with shipping fever - (Peer Reviewed Journal)
Harhay, G.P., McVey, D.S., Koren, S., Phillippy, A.M., Bono, J.L., Harhay, D.M., Clawson, M.L., Heaton, M.P., Chitko-McKown, C.G., Korlach, J., Smith, T.P. 2014. Complete closed genome sequences of three Bibersteinia trehalosi nasopharyngeal isolates from cattle with shipping fever. Genome Announcements. 2(1):e00084-14.
SNPs for parentage testing and traceability in globally diverse breeds of sheep - (Abstract Only)
Heaton, M.P., Leymaster, K.A., Kalbfleisch, T.S., Kijas, J.W., Clarke, S.M., McEwan, J., Maddox, J.F., Basnayake, V., Petrik, D.T., Simpson, B., Smith, T.P., Chitko-McKown, C.G. 2014. SNPs for parentage testing and traceability in globally diverse breeds of sheep [Abstract]. Proceedings Plant and Animal Genome XXII Conference, January 11-15, 2014, San Diego, CA. Poster P614.
Mapping whole genome shotgun sequence and variant calling in mammalian species without their reference genomes - (Peer Reviewed Journal)
Kalbfleisch, T.S., Heaton, M.P. 2014. Mapping whole genome shotgun sequence and variant calling in mammalian species without their reference genomes. F1000 Research 2:244. doi: 10.12688/f1000research.2-244.v2.
Effects of TMEM154 haplotypes 1 and 3 on susceptibility to ovine progressive pneumonia virus following natural exposure in sheep - (Peer Reviewed Journal)
Leymaster, K.A., Chitko-McKown, C.G., Clawson, M.L., Harhay, G.P., Heaton, M.P. 2013. Effects of TMEM154 haplotypes 1 and 3 on susceptibility to ovine progressive pneumonia virus following natural exposure in sheep. Journal of Animal Science. 91(11):5114-5121.
Small ruminant lentivirus genetic subgroups associate with sheep TMEM154 genotypes - (Peer Reviewed Journal)
Sider, L.H., Heaton, M.P., Chitko-Mckown, C.G., Harhay, G.P., Smith, T.P.L., Leymaster, K.A., Laegreid, W.W., and Clawson, M.L. 2013. Small ruminant lentivirus genetic subgroups associate with sheep TMEM154 genotypes. Veterinary Research. 44:64. DOI: 10.1186/1297-9716-44-64.
Complete closed genome sequences of Mannheimia haemolytica serotypes A1 and A6 isolated from cattle - (Peer Reviewed Journal)
Harhay, G.P., Koren, S., Phillippy, A.M., McVey, D.S., Kuszak, J., Clawson, M.L., Harhay, D.M., Heaton, M.P., Chitko-McKown, C.G., Smith, T.P.L. 2013. Complete closed genome sequences of Mannheimia haemolytica serotypes A1 and A6 isolated from cattle. Genome Announcements. 1(3):e00188-13. DOI: 10.1128/GENOMEA.00188-13.
Characterization of ovine Nectin-4, a novel peste des petits ruminants virus (PPRV) receptor - (Peer Reviewed Journal)
Birch, J., Juleff, N., Heaton, M.P., Kalbfleisch, T., Kijas, J., Bailey, D. 2013. Characterization of ovine Nectin-4, a novel peste des petits ruminants virus (PPRV) receptor. Journal of Virology. 87(8):4756-4761.
Rhodotorula minuta fungemia in a ewe lamb - (Peer Reviewed Journal)
Chitko-McKown, C.G., Leymaster, K.A., Heaton, M.P., Griffin, D.D., Veatch, J.K., Jones, S., Clawson, M.L. 2013. Rhodotorula minuta fungemia in a ewe lamb. Transboundary and Emerging Diseases. doi:10.1111/tbed.12062. [Epub ahead of print].
Genetic testing for TMEM154 mutations associated with lentivirus susceptibility in sheep - (Peer Reviewed Journal)
Heaton, M.P., Kalbfleisch, T.S., Petrik, D.T., Simpson, B., Kijas, J.W., Clawson, M.L., Chitko MckKown, C.G., Harhay, G.P., Leymaster, K.A. 2013. Genetic testing for TMEM154 mutations associated with lentivirus susceptibility in sheep. PLoS One. 8(2):e55490. doi:10.1371/journal.pone.0055490.
Application of SMRT genome sequencing to reveal the methylomes of bacteria associated with respiratory disease outbreaks in beef cattle - (Abstract Only)
Harhay, G.P., McVey, D.S., Korlach, J., Roberts, R., Chitko-McKown, C.G., Clawson, M.L., Heaton, M.P., Harhay, D.M., Smith, T.P.L., Anton, B.P. 2013. Application of SMRT genome sequencing to reveal the methylomes of bacteria associated with respiratory disease outbreaks in beef cattle [Abstract]. Advances in Genome Biology and Technology Conference, February 20-23, 2013, Marco Island, FL. Page 99.
Genetic testing for TMEM154 mutations associated with lentivirus susceptibility in sheep - (Abstract Only)
Heaton, M.P., Kalbfleisch, T., Petrik, D.T., Simpson, B., Kijas, J., Clawson, M.L., Chitko-McKown, C.G., Leymaster, K.A., Harhay, G.P. 2013. Genetic testing for TMEM154 mutations associated with lentivirus susceptibility in sheep [abstract]. International Plant & Animal Genome XXI Conference. No. P0625.
Mutations in ovine TMEM154 associated with reduced risk of ovine lentivirus infection are also associated with reduced proviral concentration - (Abstract Only)
Alshanbari, F., Mousel, M.R., Reynolds, J.O., Hermann-Hoesing, L.M., Heaton, M.P., Lewis, G.S., Knowles Jr, D.P., White, S.N. 2012. Mutations in ovine TMEM154 associated with reduced risk of ovine lentivirus infection are also associated with reduced proviral concentration . Annual International Plant & Animal Genome Conference. Plant & Animal Genomes Conference XXI, Abstract 0624. San Diego, CA. January 14, 2013..
Consistent divergence times and allele sharing measured from cross-species application of SNP chips developed for three domestic species - (Peer Reviewed Journal)
Miller, J.M., Kijas, J.W., Heaton, M.P., McEwan, J.C., Coltman, D.W. 2012. Consistent divergence times and allele sharing measured from cross-species application of SNP chips developed for three domestic species. Molecular Ecology Resources. 12(6):1145-1150. doi:10.1111/1755-0998.12017.
Phylogenetic clades of ovine progressive pneumonia virus (OPPV) associate with sheep TMEM154 genotypes - (Abstract Only)
Sider, L.H., Clawson, M.L., Heaton, M.P., Chitko Mckown, C.G., Harhay, G.P., Smith, T.P.L., Leymaster, K.A. 2012. Phylogenetic clades of ovine progressive pneumonia virus (OPPV) associate with sheep TMEM154 genotypes. The 58th Genomic Congress, September 11-14, 2012. Foz de Iguacu, Brazil. Poster No. GM001.
Reduced OPP susceptibility in naturally exposed lambs with homozygous TMEM154 K35 genotypes - (Abstract Only)
Chitko Mckown, C.G., Leymaster, K.A., Heaton, M.P., Clawson, M.L., Harhay, G.P. 2012. Reduced OPP susceptibility in naturally exposed lambs with homozygous TMEM154 K35 genotypes [abstract]. Immunology 2012. The 99th Annual Meeting of the American Association for Immunology, May 4-8, 2012, Boston, Massachusetts. Page 275. Abstract No. 170.3. Poster No. P1246.
Genome wide analysis of the world's sheep breeds reveals high levels of historic mixture and strong recent selection - (Peer Reviewed Journal)
Kijas, J.W., Lenstra, J.A., Porto Neto, L., Mcculloch, R., Whan, V., Gietzen, K., Paiva, S., Gill, C., Barendse, W., Ciani, E., Raadsma, H., Mcewan, J., Dalrymple, B., Heaton, M.P., et al. 2012. Genome wide analysis of the world's sheep breeds reveals high levels of historic mixture and strong recent selection. PLoS Biology. 10(2): e1001258. DOI:10.1371/journal.pbio.1001258.
Development of a SNP panel for parentage assignment in sheep - (Abstract Only)
Kijas, J.W., Mcewan, J., Clarke, S.M., Maddox, J.F., Mcculloch, R., Driver, F., Ilic, K., Heaton, M.P. 2012. Development of a SNP panel for parentage assignment in sheep [abstract]. Plant & Animal Genome XX Conference, January 14-18, 2012, San Diego, California. Poster #P0577.
Application of combined SMRT and long-read pyrosequencing to produce reference genome sequences of bacteria associated with respiratory disease outbreaks in beef cattle - (Abstract Only)
Harhay, G.P., Mcvey, D.S., Kitzmiller, A., Clamp, M., Osborne, B., Dwan, C., Zhang, J., Sisneros, N., Wang, S., Peluso, P., Bono, J.L., Chitko Mckown, C.G., Clawson, M.L., Heaton, M.P., Harhay, D.M., Smith, T.P.L. [abstract]. 2012. Application of combined SMRT and long-read pyrosequencing to produce reference genome sequences of bacteria associated with respiratory disease outbreaks in beef cattle. Advances in Genome Biology and Technology, February 15-18, 2012, Marco Island, Florida. Poster No. 129.
Reduced lentivirus susceptibility in sheep with TMEM154 mutations - (Peer Reviewed Journal)
Heaton, M.P., Clawson, M.L., Chitko-Mckown, C.G., Leymaster, K.A., Smith, T.P.L., Harhay, G.P., White, S.N., Herrmann-Hoesing, L.M., Mousel, M.R., Lewis, G.S., Kalbfleisch, T.S., Keen, J.E., Laegreid, W.W. 2012. Reduced lentivirus susceptibility in sheep with TMEM154 mutations. PLoS Genetics. 8(1): e1002467. DOI: 10.1371/journal.pgen.1002467.
A case report describing detection of Rhodoturola minuta fungemia in an ewe lamb - (Abstract Only)
Chitko Mckown, C.G., Leymaster, K.A., Heaton, M.P., Griffin, D.D., Veatch, J.K., Jones, S.A., Clawson, M.L. 2011. A case report describing detection of Rhodoturola minuta fungemia in an ewe lamb [Abstract]. Proceeding of the 2011 Conference of Research Workers in Animal Diseases, December 4-6, 2011, Chicago, Illinois. p. 95.
Discovery of a lentivirus susceptibility gene in sheep - (Abstract Only)
Heaton, M.P. 2011. Discovery of a lentivirus susceptibility gene in sheep. Queenstown Molecular Biology 2011 Meeting Abstracts.
Ovine Reference Materials and Assays for Prion Genetic Testing - (Peer Reviewed Journal)
Heaton, M.P., Leymaster, K.A., Kalbfleisch, T.S., Freking, B.A., Smith, T.P., Clawson, M.L., Laegreid, W.W. 2010. Ovine Reference Materials and Assays for Prion Genetic Testing. BioMed Central (BMC) Veterinary Research [serial online]. 6:23. Available: http://www.biomedcentral.com/1746-6148/6/23.
Ovine Reference Materials and Assays for Prion Genetic Testing - (Abstract Only)
Heaton, M.P., Leymaster, K.A., Kalbfleisch, T.S., Freking, B.A., Smith, T.P., Clawson, M.L., Laegreid, W.W. 2009. Ovine Reference Materials and Assays for Prion Genetic Testing [abstract]. Plant and Animal Genomes XVIII Conference. Abstract No. P577. Available: http://www.intl-pag.org/18/abstracts/
Discovery, Validation and Characterization of 1039 Cattle Single Nucleotide Polymorphisms - (Peer Reviewed Journal)
Donthu, R., Larkin, D.M., Heaton, M.P., Lewin, H.A. 2010. Discovery, Validation and Characterization of 1039 Cattle Single Nucleotide Polymorphisms. Animal Genetics. 41(4):421-423.
Resolving the Evolution of Extant and Extinct Ruminants With High-Throughput Phylogenomics - (Peer Reviewed Journal)
Decker, J.E., Pires, J.C., Conant, G.C., McKay, S.D., Heaton, M.P., Chen, K., Cooper, A., Vilkki, J., Seabury, C.M., Caetano, A.R., Johnson, G.S., Brenneman, R.A., Hanotte, O., Eggert, L.S., Wiener, P., Kim, J.J., Kim, K.S., Sonstegard, T.S., Van Tassell, C.P., Neibergs, H.L., McEwan, J.C., Brauning, R., Coutinho, L.L., Babar, M.E., Wilson, G.A., McClure, M.C., Rolf, M.M., Kim, J., Schnabel, R.D., Taylor, J.F. 2009. Resolving the Evolution of Extant and Extinct Ruminants With High-Throughput Phylogenomics. Proceedings of the National Academy of Sciences. 106(44):18644-18649.
Frequent Missense and Insertion/Deletion Polymorphisms in the Ovine Shadoo Gene Parallel Species-Specific Variation in PrP - (Peer Reviewed Journal)
Daude, N., Wohlgemuth, S., Rogaeva, E., Farid, A.H., Heaton, M.P., Westaway, D. 2009. Frequent Missense and Insertion/Deletion Polymorphisms in the Ovine Shadoo Gene Parallel Species-Specific Variation in PrP. PLoS One [serial online]. 4(8):e6538.
HIGH-THROUGHPUT PHYLOGENOMICS: FROM ANCIENT DNA TO SIGNATURES OF HUMAN ANIMAL HUSBANDRY - (Abstract Only)
Decker, J.E., Pires, J.C., Conant, G.C., Mckay, S.D., Heaton, M.P., Vilkki, J., Seabury, C.M., Caetano, A.R., Johnson, G.S., Brenneman, R.A., Hanotte, O., Eggert, L.S., Wiener, P., Kim, J., Kim, K.S., Sonstegard, T.S., Van Tassell, C.P., Neibergs, H.L., Chen, K., Cooper, A., Mcewan, J.C., Brauning, R., Coutinho, L.L., Babar, M.E., Wilson, G.A., Mcclure, M.C., Rolf, M.M., Kim, J., Schnabel, R.D., Taylor, J.F. 2009. HIGH-THROUGHPUT PHYLOGENOMICS: FROM ANCIENT DNA TO SIGNATURES OF HUMAN ANIMAL HUSBANDRY. Cold Spring Harbor Meeting.
Development and Characterization of a High Density SNP Genotyping Assay for Cattle - (Peer Reviewed Journal)
Matukumalli, L.K., Lawley, C.T., Schnabel, R.D., Taylor, J.F., Allan, M.F., Heaton, M.P., O'Connell, J., Moore, S.S., Smith, T.P., Sonstegard, T.S., Van Tassell, C.P. 2009. Development and Characterization of a High Density SNP Genotyping Assay for Cattle. PLoS One. 4(4):e5350. Available: http://dx.doi.org/10.1371/journal.pone.0005350.
A Genome Wide Survey of SNP Variation Reveals the Genetic Structure of Sheep Breeds - (Peer Reviewed Journal)
Kijas, J.W., Townley, D., Dalrymple, B.P., Heaton, M.P., Maddox, J.F., McGrath, A., Wilson, P., Ingersoll, R.G., McCulloch, R., McWilliam, S., Tang, D., McEwan, J., Cockett, N., Oddy, V.H., Nicholas, F.W., Raadsma, H. 2009. A Genome Wide Survey of SNP Variation Reveals the Genetic Structure of Sheep Breeds. PLoS One [serial online]. 4(3):e4668. Available: http://www.plosone.org.
A web-based genome browser for 'SNP-aware' assay design - (Abstract Only)
Morris, J.P., Heaton, M.P., Kalbfleisch, T.S. 2009. A web-based genome browser for 'SNP-aware' assay design [abstract]. Plant and Animal Genomes XVII Conference. Abstract No. CP843. Available: http://www.intl-pag.org/17/abstracts/
Prevalence of the prion gene E211K variant in U.S. cattle - (Peer Reviewed Journal)
Heaton, M.P., Keele, J.W., Harhay, G.P., Richt, J., Koohmaraie, M., Wheeler, T.L., Shackelford, S.D., Casas, E., King, D.A., Sonstegard, T.S., Van Tassell, C.P., Neibergs, H.L., Chase, C.C., Kalbfleisch, T.S., Smith, T.P., Clawson, M.L., Laegreid, W.W. 2008. Prevalence of the prion gene E211K variant in U.S. cattle. BioMed Central (BMC) Veterinary Research [journal online]. 4:25. Available: (http://www.biomedcentral.com/1746-6148/4/25).
Scrapie resistance in ARQ sheep - (Peer Reviewed Journal)
Laegreid, W.W., Clawson, M.L., Heaton, M.P., Green, B.T., Orourke, K.I., Knowles Jr, D.P. 2008. Scrapie resistance in ARQ sheep. Journal of Virology. 82(20):10318-10320. Available: DOI:10.1128/JVI.00710-08.
A sequencing strategy for identifying variation throughout the prion gene of BSE-affected cattle - (Peer Reviewed Journal)
Clawson, M.L., Heaton, M.P., Keele, J.W., Smith, T.P., Harhay, G.P., Richt, J., Laegreid, W.W. 2008. A sequencing strategy for identifying variation throughout the prion gene of BSE-affected cattle. BMC Research Notes [journal online]. 1:32. Available: http://www.biomedcentral.com/1756-0500/1/32.
Association of a bovine prion gene haplotype with atypical BSE - (Peer Reviewed Journal)
Clawson, M.L., Richt, J., Baron, T., Biacabe, A., Czub, S., Heaton, M.P., Smith, T.P., Laegreid, W.W. 2008. Association of a bovine prion gene haplotype with atypical BSE. PLoS One [serial online]. 3(3):e1830. Available: http://www.plosone.org.
Prevalence of the prion gene E211K variant in U.S. cattle - (Abstract Only)
Heaton, M.P., Keele, J.W., Harhay, G.P., Richt, J., Koohmaraie, M., Wheeler, T.L., Shackelford, S.D., Casas, E., King, D.A., Sonstegard, T.S., Van Tassell, C.P., Neibergs, H.L., Chase, C.C., Kalbfleisch, T.S., Smith, T.P., Clawson, M.L., Laegreid, W.W. 2008. Prevalence of the prion gene E211K variant in U.S. cattle (abstract). Plant and Animal Genome XVI Conference. Poster No. P538.
Scrapie resistance in ARQ sheep - (Abstract Only)
Laegreid, W.W., Clawson, M.L., Heaton, M.P., Green, B.T., Orourke, K.I., Knowles Jr, D.P. 2008. Scrapie resistance in ARQ sheep (abstract). Plant and Animal Genome XVI Conference. Poster No. P550.
Association of Escherichia coli O157:H7 tir polymorphisms in human infection - (Peer Reviewed Journal)
Bono, J.L., Keen, J.E., Clawson, M.L., Durso, L.M., Heaton, M.P., Laegreid, W.W. 2007. Association of Escherichia coli O157:H7 tir polymorphisms with human infection. BMC Infectious Diseases. 7:98.
Genome scan for BSE susceptibility and/or resistance in European Holstein cattle - (Abstract Only)
Murdoch, B., Mckay, S., Prasad, A., Marques, E., Kolbehdari, D., Wang, Z., Stella, A., Clawson, M.L., Heaton, M.P., Laegreid, W.W., Moore, S., Williams, J. 2007. Genome scan for BSE susceptibility and/or resistance in European Holstein cattle [abstract]. Prion 2007 Conference. Abstract No. P03.126.
Prion gene haplotypes of U.S. cattle - (Peer Reviewed Journal)
Clawson, M.L., Heaton, M.P., Keele, J.W., Smith, T.P., Harhay, G.P., Laegreid, W.W. 2006. Prion gene haplotypes of U.S. cattle. BioMed Central (BMC) Genetics. 7:51.
Polymorphisms and haplotype structure of bovine PRND (doppel) and PRNT - (Abstract Only)
Laegreid, W.W., Clawson, M.L., Smith, T.P., Harhay, G.P., Keele, J.W., Heaton, M.P. 2007. Polymorphisms and haplotype structure of bovine PRND (doppel) and PRNT [abstract]. Plant and Animal Genome XV Conference. Poster No. P535.
Genome adaptations of a tripartite motif protein for retroviral defense in cattle and sheep - (Abstract Only)
Smith, T.P., Heaton, M.P., Snelling, W.M., Ylinen, L., Keckesova, Z., Webb, B.L., Towers, G.J. 2007. Genome adaptations of a tripartite motif protein for retroviral defense in cattle and sheep [abstract]. Plant and Animal Genome XV Conference. Poster No. P540.
A rapid sequence-based method for comprehensive polymorphism identification within a 25.2-kb region of the bovine prion gene in BSE-affected cattle - (Abstract Only)
Clawson, M.L., Heaton, M.P., Keele, J.W., Smith, T.P., Harhay, G.P., Laegreid, W.W. 2007. A rapid sequence-based method for comprehensive polymorphism identification within a 25.2-kb region of the bovine prion gene in BSE-affected cattle [abstract]. Plant and Animal Genome XV Conference. Poster No. P533.
A marker set for parentage-based DNA traceback in beef and dairy cattle - (Abstract Only)
Heaton, M.P., Snelling, W.M., Smith, T.P., Keele, J.W., Harhay, G.P., Wiedmann, R.T., Bennett, G.L., Freking, B.A., Van Tassell, C.P., Sonstegard, T.S., Gasbarre, L.C., Moore, S.S., Murdoch, B., Mckay, S.D., Kalbfleisch, T., Laegreid, W.W. 2007. A marker set for parentage-based DNA traceback in beef and dairy cattle [abstract]. Plant and Animal Genome XV Conference. Poster No. P516.
Development of a web services based system for dissemination of single nucleotide polymorphism data - (Abstract Only)
Heaton, M.P., Morris, J., Eltonsy, N., Rouchka, E., Kalbfleisch, T. 2007. Development of a web services based system for dissemination of single nucleotide polymorphism data [abstract]. Plant and Animal Genome XV Conference. Poster No. P517.
LINKAGE DISEQUILIBRIUM ACROSS SIX PRION GENE REGIONS SPANNING 20 KBP IN U.S. SHEEP - (Peer Reviewed Journal)
Green, B.T., Heaton, M.P., Clawson, M.L., Laegreid, W.W. 2006. Linkage disequilibrium across six prion gene regions spanning 20 kbp in U.S. sheep. Mammalian Genome. 17(11):1121.1129.
CHARACTERIZATION OF 954 BOVINE FULL-CDS CDNA SEQUENCES - (Peer Reviewed Journal)
Harhay, G.P., Sonstegard, T.S., Keele, J.W., Heaton, M.P., Clawson, M.L., Snelling, W.M., Wiedmann, R.T., Van Tassell, C.P., Smith, T.P. 2005. Characterization of 954 bovine full-CDS cDNA sequences. Biomed Central (BMC) Genomics 6:166 (11 pp).
EVALUATION OF ASSOCIATIONS BETWEEN PRION HAPLOTYPES AND GROWTH, CARCASS, AND MEAT QUALITY TRAITS IN A DORSET X ROMANOV SHEEP POPULATION - (Peer Reviewed Journal)
Isler, B.J., Freking, B.A., Thallman, R.M., Heaton, M.P., Leymaster, K.A. 2006. Evaluation of associations between prion haplotypes and growth, carcass, and meat quality traits in a Dorset x Romanov sheep population. Journal of Animal Science. 84:783-788.
IN SILICO DISCOVERY, MAPPING, AND GENOTYPING OF 1,039 CATTLE SNPS ON A PANEL OF EIGHTEEN BREEDS - (Abstract Only)
Donthu, R., Larkin, D.M., Heaton, M.P., Lewin, H.A. 2006. In silico discovery, mapping, and genotyping of 1,039 cattle SNPs on a panel of eighteen breeds [abstract]. Plant and Animal Genome Conference Proceedings. p. 235.
USE OF BOVINE SINGLE NUCLEOTIDE POLYMORPHISM MARKERS FOR CONFIRMATION OF IDENTITY AND PARENTAGE - (Abstract Only)
Laegreid, W.W., Clawson, M.L., Heaton, M.P. 2005. Use of bovine single nucleotide polymorphism markers for confirmation of identity and parentage [abstract]. United States Animal Health Association. p. 710.
LINKAGE DISEQUILIBRIUM AND HAPLOTYPE STRUCTURE IN THE PRION GENE OF U.S. BEEF AND DAIRY CATTLE - (Abstract Only)
Clawson, M.L., Heaton, M.P., Keele, J.W., Smith, T.P., Laegreid, W.W. 2006. Linkage disequilibrium and haplotype structure in the prion gene of U.S. beef and dairy cattle (abstract). Plant and Animal Genome Conference Proceedings. p. 145.
A FREELY-AVAILABLE SET OF REFERENCE DNAS FOR GENOTYPING THE MAJOR SCRAPIE SUSCEPTIBILITY ALLELES IN SHEEP - (Abstract Only)
Heaton, M.P., Leymaster, K.A., Clawson, M.L., Freking, B.A., Laegreid, W.W. 2006. A freely-available set of reference DNAs for genotyping the major scrapie susceptibility alleles in sheep [abstract]. Plant and Animal Genome Conference Proceedings. p. 239.
DISCRIMINTION OF ESCHERICHIA COLI O157:H7 ISOLATES BY GENOTYPING SINGLE NUCLEOTIDE POLYMORPHISMS - (Abstract Only)
Bono, J.L., Keen, J.E., Clawson, M.L., Heaton, M.P., Chitko Mckown, C.G., Miller, L.C., Laegreid, W.W. 2005. Discrimintion of Escherichia coli O157:H7 isolates by genotyping single nucleotide polymorphisms. [abstract] American Society of Microbiologists. p. 318.
BOVINE SINGLE NUCLEOTIDE POLYMORPHISMS (SNPS) AND THEIR USE IN ANIMAL IDENTIFICATION, PARENTAGE TESTING, AND TRACEBACK - (Abstract Only)
Heaton, M.P. 2005. Bovine single nucleotide polymorphisms (SNPs) and their use in animal identification, parentage testing, and traceback [abstract]. Midwestern Section of the American Society of Animal Science. p.8.
EFFECTS OF PRION HAPLOTYPE ON GROWTH AND CARCASS TRAITS IN SHEEP - (Peer Reviewed Journal)
Isler, B.J., Freking, B.A., Heaton, M.P., Thallman, R.M., Leymaster, K.A. 2005. Effects of prion haplotype on growth and carcass traits in sheep [abstract]. Midwestern Section of the American Society of Animal Science. 83(Suppl. 2):44-45
IDENTIFICATION OF POLYMORPHISMS IN NON-CODING REGIONS OF THE OVINE PRNP GENE - (Abstract Only)
Green, B.T., Clawson, M.L., Heaton, M.P., Chitko Mckown, C.G., Fox, J.M., Laegreid, W.W. 2004. Identification of polymorphisms in non-coding regions of the ovine PRNP gene [abstract]. Research Workers in Animal Diseases Conference. p. 90.
USE OF BOVINE SNP MARKERS TO VERIFY SAMPLE TRACKING IN BEEF PROCESSING - (Abstract Only)
Heaton, M.P., Keen, J.E., Clawson, M.L., Harhay, G.P., Bauer, N., Shultz, C., Green, B.T., Durso, L.M., Chitko Mckown, C.G., Laegreid, W.W. Use of bovine SNP markers to verify sample tracking in beef processing [abstract]. Plant and Animal Genome Conference Proceedings. p. 124.
USE OF BOVINE SINGLE NUCLEOTIDE POLYMORPHISM MARKERS TO VERIFY SAMPLE TRACKING IN BEEF PROCESSING - (Peer Reviewed Journal)
Heaton, M.P., Keen, J.E., Clawson, M.L., Harhay, G.P., Bauer, N., Schultz, C., Green, B.T., Durso, L.M., Chitko Mckown, C.G., Laegreid, W.W. 2005. Use of bovine single nucleotide polymorphism markers to verify sample tracking in beef processing. Journal of the American Veterinary Medical Association 226(8):1311-1314.
DISCRIMINATION OF ESCHERICHIA COLI O157:H7 FROM OTHER BACTERIA BY GENOTYPING SINGLE NUCLEOTIDE POLYMORPHISMS - (Abstract Only)
Bono, J.L., Keen, J.E., Clawson, M.L., Heaton, M.P., Fox, J.M., Chitko McKown, C.G., Laegreid, W.W. 2004. Discrimination of Escherichia coli O157:H7 from other bacteria by genotyping single nucleotide polymorphisms [abstract]. American Society for Microbiology. Paper No. C-311.
CORRELATION OF SRY AND ZFY ALLELES OF THE Y CHROMOSOME IN U.S. BEEF CATTLE - (Abstract Only)
CLAWSON, M.L., HEATON, M.P., FOX, J.M., CHITKO MCKOWN, C.G., SMITH, T.P., LAEGREID, W.W. CORRELATION OF SRY AND ZFY ALLELES OF THE Y CHROMOSOME IN U.S. BEEF CATTLE. PLANT AND ANIMAL GENOME CONFERENCE PROCEEDINGS. 2004. ABSTRACT NO. P310.
PRION GENE SEQUENCE VARIATION WITHIN DIVERSE GROUPS OF U.S. SHEEP, BEEF CATTLE, AND DEER - (Abstract Only)
HEATON, M.P., LEYMASTER, K.A., FREKING, B.A., HAWK, D.A., KEELE, J.W., LAEGREID, W.W. PRION GENE SEQUENCE VARIATION WITHIN DIVERSE GROUPS OF U.S. SHEEP, BEEF CATTLE, AND DEER. PLANT AND ANIMAL GENOME CONFERENCE PROCEEDINGS. 2004. ABSTRACT NO. P311.
ACCURATE DETERMINATION OF PRNP HAPLOTYPES IN U.S. SHEEP - (Abstract Only)
HEATON, M.P., LEYMASTER, K.A., FREKING, B.A., LAEGREID, W.W. ACCURATE DETERMINATION OF PRNP HAPLOTYPES IN U.S. SHEEP. PLANT AND ANIMAL GENOME CONFERENCE PROCEEDINGS. 2004. ABSTRACT NO. P312.
GENETIC RISK FACTORS FOR FAILURE OF PASSIVE TRANSFER IN THE BOVINE NEONATAL FC RECEPTOR - (Abstract Only)
LAEGREID, W.W., CLAWSON, M.L., HEATON, M.P., KEEN, J.E., CHITKO MCKOWN, C.G., FOX, J.M., SMITH, T.P., SNELLING, W.M., KEELE, J.W. GENETIC RISK FACTORS FOR FAILURE OF PASSIVE TRANSFER IN THE BOVINE NEONATAL FC RECEPTOR. PLANT AND ANIMAL GENOME CONFERENCE PROCEEDINGS. ABSTRACT NO. P642.
MALE-SPECIFIC SRY AND ZFY HAPLOTYPES IN U.S. BEEF CATTLE - (Peer Reviewed Journal)
Clawson, M.L., Heaton, M.P., Fox, J.M., Chitko Mckown, C.G., Smith, T.P., Laegreid, W.W. 2004. Male-specific SRY and ZFY haplotypes in U.S. beef cattle. Animal Genetics. 35(3):246-249.
EVALUATION OF A REAL-TIME PCR KIT FOR DETECTING ESCHERICHIA COLI O157 IN BOVINE FECAL SAMPLES - (Peer Reviewed Journal)
BONO, J.L., KEEN, J.E., MILLER, L.C., FOX, J.M., CHITKO MCKOWN, C.G., HEATON, M.P., LAEGREID, W.W. EVALUATION OF A REAL-TIME PCR KIT FOR DETECTING ESCHERICHIA COLI O157 IN BOVINE FECAL SAMPLES. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 2004. V. 70. P. 1855-1857.
BETA-2-MICROGLOBULIN HAPLOTYPES IN U.S. BEEF CATTLE AND ASSOCIATION WITH FAILURE OF PASSIVE TRANSFER IN NEWBORN CALVES - (Peer Reviewed Journal)
Clawson, M.L., Heaton, M.P., Chitko Mckown, C.G., Fox, J.M., Smith, T.P., Snelling, W.M., Keele, J.W., Laegreid, W.W. 2004. Beta-2-microglobulin haplotypes in u.s. beef cattle and association with failure of passive transfer in newborn calves. Mammalian Genome. 2004. V. 15. P. 227-236.
GENE EXPRESSION PROFILING OF BOVINE MACROPHAGES IN RESPONSE TO ESCHERICHIA COLI O157:H7 LIPOPOLYSACCHARIDE - (Abstract Only)
CHITKO MCKOWN, C.G., FOX, J.M., MILLER, L.C., HEATON, M.P., BONO, J.L., KEEN, J.E., GROSSE, W.M., LAEGREID, W.W. GENE EXPRESSION PROFILING OF BOVINE MACROPHAGES IN RESPONSE TO ESCHERICHIA COLI O157:H7 LIPOPOLYSACCHARIDE. IMMUNOLOGY RESEARCH WORKSHOP. 2003. ABSTRACT NO. 23.
GENE EXPRESSION PROFILING OF BOVINE MACROPHAGES IN RESPONSE TO ESCHERICHIA COLI O157:H7 LIPOPOLYSACCHARIDE - (Peer Reviewed Journal)
CHITKO MCKOWN, C.G., FOX, J.M., MILLER, L.C., HEATON, M.P., BONO, J.L., KEEN, J.E., GROSSE, W.M., LAEGREID, W.W. GENE EXPRESSION PROFILING OF BOVINE MACROPHAGES IN RESPONSE TO ESCHERICHIA COLI O157:H7 LIPOPOLYSACCHARIDE. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. 2004. V. 28. P. 635-645.
EFFECT OF EXOGENOUS GLUCOCORTICOIDS AND DIETARY CHANGE ON WINTER AND SUMMER STEC O157 FECAL SHEDDING IN NATURALLY-INFECTED BEEF CATTLE - (Abstract Only)
KEEN, J.E., LAEGREID, W.W., CHITKO MCKOWN, C.G., BONO, J.L., FOX, J.M., CLAWSON, M.L., HEATON, M.P. EFFECT OF EXOGENOUS GLUCOCORTICOIDS AND DIETARY CHANGE ON WINTER AND SUMMER STEC O157 FECAL SHEDDING IN NATURALLY-INFECTED BEEF CATTLE. RESEARCH WORKERS IN ANIMAL DISEASES CONFERENCE PROCEEDINGS. 2003. ABSTRACT NO. 83.
PRION GENE SEQUENCE VARIATION WITHIN DIVERSE GROUPS OF U.S. SHEEP, BEEF CATTLE, AND DEER - (Peer Reviewed Journal)
HEATON, M.P., LEYMASTER, K.A., FREKING, B.A., HAWK, D.A., SMITH, T.P., KEELE, J.W., SNELLING, W.M., FOX, J.M., CHITKO MCKOWN, C.G., LAEGREID, W.W. PRION GENE SEQUENCE VARIATION WITHIN DIVERSE GROUPS OF U.S. SHEEP, BEEF CATTLE, AND DEER. MAMMALIAN GENOME. 2003. V. 14. P. 765-777.
ASSOCIATION OF NOS2A HAPLOTYPES AND BACTERICIDAL ACTIVITY OF BOVINE MONOCYTE-DERIVED MACROPHAGES - (Abstract Only)
CHITKO MCKOWN, C.G., HEATON, M.P., GROSSE, W.M., KEEN, J.E., BONO, J.L., CLAWSON, M.L., FOX, J.M., MILLER, L.C., LAEGREID, W.W. ASSOCIATION OF NOS2A HAPLOTYPES AND BACTERICIDAL ACTIVITY OF BOVINE MONOCYTE-DERIVED MACROPHAGES. AMERICAN ASSOCIATION OF IMMUNOLOGISTS PROCEEDINGS. 2003. Abstract No. 150.1.
BETA2-MICROGLOBULIN HAPLOTYPE STRUCTURE IN U.S. BEEF CATTLE AND CORRELATION WITH SERUM IGG CONCENTRATION IN NEWBORN CALVES - (Abstract Only)
CLAWSON, M.L., HEATON, M.P., LAEGREID, W.W. BETA2-MICROGLOBULIN HAPLOTYPE STRUCTURE IN U.S. BEEF CATTLE AND CORRELATION WITH SERUM IGG CONCENTRATION IN NEWBORN CALVES. PLANT AND ANIMAL GENOME CONFERENCE PROCEEDINGS. 2003. Abstract No. P261.
ASSOCIATION OF BOVINE NEONATAL FC RECEPTOR GENE (FCGRT) HAPLOTYPES WITH SERUM IGG CONCENTRATION IN NEWBORN CALVES - (Peer Reviewed Journal)
LAEGREID, W.W., HEATON, M.P., KEEN, J.E., GROSSE, W.M., CHITKO MCKOWN, C.G., SMITH, T.P., KEELE, J.W., BENNETT, G.L., BESSER, T.E. ASSOCIATION OF BOVINE NEONATAL FC RECEPTOR GENE ALPHA-CHAIN GENE (FCGRT) HAPLOTYPES WITH SERUM IgG CONCENTRATION IN NEWBORN CALVES. MAMMALIAN GENOME. 2002. v. 13. p. 704-710.
EVALUATION OF SINGLE NUCLEOTIDE POLYMORPHISMS IN CAPN1 FOR ASSOCIATION WITH MEAT TENDERNESS IN CATTLE. - (Peer Reviewed Journal)
Page, B.T., Casas, E., Heation, M.P., Cullen, N.G., Hyndman, D.L., Morris, C.A., Crawford, A.M., Wheeler, T.L., Koohmaraie, M., Keele, J.W., Smith, T.P.L. Journal Animal Science. 2002. v. 80. p. 3077-3085.
SELECTION AND USE OF SNP MARKERS FOR ANIMAL IDENTIFICATION AND PATERNITY ANALYSIS IN U.S. BEEF CATTLE - (Peer Reviewed Journal)
Mammalian Genome. 2002. v. 13. p. 272-281.
SELECTION AND USE OF SINGLE NUCLEOTIDE POLYMORPHISM (SNP) MARKERS FOR ANIMAL IDENTIFICATION AND PATERNITY ANALYSIS IN U.S. BEEF CATTLE - (Abstract Only)
HAPLOTYPE STRUCTURE OF THE BOVINE NEONATAL FC RECEPTOR (BFCRN) GENE IN U.S.BEEF CATTLE AND ASSOCIATION WITH SERUM IGG CONCENTRATION IN NEWBORN CALVES - (Abstract Only)
DISTRIBUTION OF INDUCIBLE NITRIC OXIDE SYNTHASE (NOS2) HAPLOTYPES IN U.S. BEEF CATTLE - (Abstract Only)
DNA SEQUENCE DIVERSITY AND HAPLOTYPE RELATIONSHIPS AT GENE LOCI IN U.S. BEEF CATTLE POPULATIONS - (Abstract Only)
INTERLEUKIN-8 HAPLOTYPE STRUCTURE FROM NUCLEOTIDE SEQUENCE VARIATION IN COMMERCIAL POPULATIONS OF U.S. BEEF CATTLE - (Peer Reviewed Journal)
Heaton, M.P., Chitko Mckown, C.G., Grosse, W.M., Keele, J.W., Keen, J.E., Laegreid, W.W. 2001. Interleukin-8 haplotype structure from nucleotide sequence variation in commercial populations of U.S. beef cattle. Mammalian Genome. 12:219-226.
ALLELIC VARIATION IN BOTH CODING AND NON-CODING REGIONS OF THE BOVINE INTERLEUKIN-13 GENE - (Abstract Only)
ESTIMATION OF DNA SEQUENCE DIVERSITY IN BOVINE CYTOKINE GENES - (Peer Reviewed Journal)
Heaton, M.P., Grosse, W.M., Kappes, S.M., Keele, J.W., Chitko Mckown, C.G., Cundiff, L.V., Braun, A., Little, D.P., Laegreid, W.W. 2001. Estimation of DNA sequence diversity in bovine cytokine genes. Mammalian Genome. 12:32-37.
IDENTIFICATION OF ALLELIC VARIATION WITHIN THE BOVINE INTERLEUKIN-13 GENE - (Abstract Only)
ALLELIC VARIATION IN THE BOVINE INTERLEUKIN-10 GENE - (Abstract Only)
STRUCTURE OF THE GENES FOR PORCINE ENDOMETRIAL SECRETED AND MEMBRANE FOLATE BINDING PROTEINS - (Peer Reviewed Journal)
Vallet, J.L., Smith, T.P., Sonstegard, T.S., Heaton, M.P., Fahrenkrug, S.C. 2001. Structure of the genes for porcine endometrial secreted and membrane folate binding proteins. Domestic Animal Endocrinology. 21(1):55-72.
INTERLEUKIN-8 HAPLOTYPE STRUCTURE FROM NUCLEOTIDE SEQUENCE VARIATION IN COMMERCIAL POPULATIONS OF U.S. BEEF CATTLE - (Abstract Only)
CHARACTERIZATION OF THE GENE FOR PORCINE ENDOMETRIAL/PLACENTAL MEMBRANE FOLATE BINDING PROTEIN (MFBP) - (Abstract Only)
Vallet, J.L., Smith, T.P., Sonstegard, T.S., Heaton, M.P., Fahrenkrug, S.C. 2000. Characterization of the gene for porcine endometrial/placental membrane folate binding protein (mFBP) [abstract]. Journal of Animal Science. 78(Supplement 2):77. (Abstract No. 231)
DEVELOPMENT OF SINGLE NUCLEOTIDE POLYMORPHISM (SNP) MARKERS FOR BOVINE NEONATAL FC RECEPTOR - (Abstract Only)
SINGLE NUCLEOTIDE POLYMORPHISMS (SNPS) IN THE BOVINE INDUCIBLE NITRIC OXIDE SYNTHASE (BNOS2) GENE - (Abstract Only)
SNP FREQUENCY AND HAPLOTYPE DIVERSITY IN BEEF CATTLE CYTOKINE GENES - (Abstract Only)
SINGLE NUCLEOTIDE POLYMORPHISM (SNP) DISCOVERY AND LINKAGE MAPPING OF BOVINE CYTOKINE GENES - (Peer Reviewed Journal)
Grosse, W.M., Kappes, S.M., Laegreid, W.W., Keele, J.W., Chitko Mckown, C.G., Heaton, M.P. 1999. Single nucleotide polymorphism (SNP) discovery and linkage mapping of bovine cytokine genes. Mammalian Genome. 10:1062-1069.
IDENTIFICATION, SINGLE NUCLEOTIDE POLYMORPHISM (SNP) DISCOVERY, AND LINKAGE MAPPING OF BOVINE IMMUNE RESPONSE GENES - (Abstract Only)
GENETIC VARIATION IN BEEF CATTLE CYTOKINE GENES: FREQUENCY OF SNPS IN THE MARC REFERENCE FAMILY - (Abstract Only)
DEVELOPMENT OF SINGLE NUCLEOTIDE POLYMORPHISM (SNP) MARKERS FOR BOVINE C-X-C CHEMOKINE GENES - (Abstract Only)
IDENTIFICATION AND GENETIC MAPPING OF BOVINE CHEMOKINE GENES EXPRESSED IN EPITHELIAL CELLS - (Peer Reviewed Journal)
MAPPING BOVINE AND OVINE GENES WITH INTRONIC SINGLE NUCLEOTIDE POLYMORPHISMS - (Abstract Only)
STRUCTURE OF THE GENE FOR PORCINE ENDOMETRIAL FOLATE BINDING PROTEIN - (Abstract Only)
EXPRESSION-BASED GENE IDENTIFICATION AND SINGLE NUCLEOTIDE POLYMORPHISM (SNP) MAPPING IN CATTLE - (Abstract Only)
ESTIMATION OF GENOMIC COVERAGE AND GENETIC LENGTH OF THE BOVINE GENOME - (Proceedings)
GENE EXPRESSION IN BOVINE EPITHELIAL CELLS: IDENTIFICATION OF CHEMOKINE GENES INDUCED BY ESCHERICHIA COLI O157:H7 LIPOPOLYSACCHARIDE - (Abstract Only)
CATTLE GENE MAPPING: ESTIMATION OF CHROMOSOME COVERAGE BY FLUORESCENCE IN SITU HYBRIDIZATION OF MICROSATELLITES AT THE ENDS OF THE LINKAGE GROUPS FOR BTA1, 3, 15, 16, 17, 20, 22, 28 AND 29 - (Proceedings)
DIRECTED COSMID ISOLATION FOR PHYSICAL ASSIGNMENT BY FISH: PCR-BASED ITERATIVE SCREENING OF RANDOM GENOMIC LIBRARIES - (Peer Reviewed Journal)