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United States Department of Agriculture

Agricultural Research Service

Huawei Zeng
Research Molecular Biologist


Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Opposing impacts on healthspan and longevity by limiting dietary selenium in Telomere Dysfunctional mice -
Loss of selenium-binding protein 1 decreases sensitivity to clastogens and intracellular selenium content in HeLa cells -
Zhai, C., Wu, R., Zeng, H., Cheng, W. 2016. Loss of selenium-binding protein 1 decreases sensitivity to clastogens and intracellular selenium content in HeLa cells. PLoS One. 11(7):DOI:10.1371/journal.pone.0158650.
Colonic inflammation and enhanced-beta-catenin signaling accompany an increase of the Lachnospiraceae/Streptococcaceae in the hind gut of high-fat diet-fed mice -
Novel correlations between microbial taxa and amino acid metabolites in mouse cecal contents -
Taussig, D.P., Jackson, M., Zeng, H., Combs, Jr., G.F. 2016. Novel correlations between microbial taxa and amino acid metabolites in mouse cecal contents [abstract]. Keystone Symposia: Microbiota, Metabollic Disorders and Beyond, April 17-21, 2016, Newport, Rhode Island. p 75.
Butyrate plays differential roles in cellular signaling in cancerous HCT116 and noncancerous NCM460 colon cells -
Zeng, H., Taussig, D.P., Cheng, W., Hakkak, R. 2016. Butyrate plays differential roles in cellular signaling in cancerous HCT116 and noncancerous NCM460 colon cells [abstract]. Federation of American Societies for Experimental Biology Conference, April 1-6, 2016, San Diego, California. 30:688.9.
Colonic inflammation and enhanced-beta-catenin signaling accompany an increase of the Lachnospiraceae/Streptococcaceae in the hind gut of high-fat diet-fed mice -
Zeng, H., Ishaq, S.L., Zhao, F., Wright, A.G. 2016. Colonic inflammation and enhanced-beta-catenin signaling accompany an increase of the Lachnospiraceae/Streptococcaceae in the hind gut of high-fat diet-fed mice [abstract]. Federation of American Societies for Experimental Biology Conference, April 1-6, 2016, San Diego, California. 30:1166.4.
Climatic thresholds for concentrations of minerals and heavy metals in Argentinean soybeans Reprint Icon -
Marioli Nobile, C.G., Balzarini, M., Aguate, F.M., Grosso, N., Soldini, D.O., Zeng, H., Cheng, W., Martinez, M. 2016. Climatic thresholds for concentrations of minerals and heavy metals in Argentinean soybeans. Agronomy Journal. 108(2):532-539.
Integrating multiple analytical datasets to compare metabolite profiles of mouse colonic-cecal contents and feces Reprint Icon -
Zeng, H., Grapov, D., Fahrmann, J., Fiehn, O., Combs, G.F. 2015. Integrating multiple analytical datasets to compare metabolite profiles of mouse colonic-cecal contents and feces. Metabolites. 5:489-501.
Short and long-term soy diet vs. casein protects liver steatosis independent of the arginine content Reprint Icon -
Hakkak, R., Zeng, H., Korourian, S. 2015. Short and long-term soy diet vs. casein protects liver steatosis independent of the arginine content. British Journal of Nutrition [epub ahead of print]. http://online.liebertpub.com/doi/10.1089/jmf.2015.0002.
Butyrate and deoxycholic acid play common and distinct roles in HCT116 human colon cell proliferation Reprint Icon -
Zeng, H., Claycombe, K.J., Reindl, K.M. 2015. Butyrate and deoxycholic acid play common and distinct roles in HCT116 human colon cell proliferation. Journal of Nutritional Biochemistry. 26:1022-1028.
The inhibitory efficacy of methylseleninic acid against colon cancer xenografts in C57BL/6 mice Reprint Icon -
Zeng, H., Wu, M. 2015. The inhibitory efficacy of methylseleninic acid against colon cancer xenografts in C57BL/6 mice. Nutrition and Cancer. 67(5):831-838.
Integrated datasets characterize metabolic interactions between mouse’s colonic mucosa, colonic-cecal contents and feces -
Zeng, H., Grapov, D., Jackson, M.I., Fahrmann, J., Fiehn, O., Combs, G.F. 2015. Integrated datasets characterize metabolic interactions between mouse’s colonic mucosa, colonic-cecal contents and feces [abstract]. Journal of Federation of American Societies for Experimental Biology. 29:748.7.
Butyrate and deoxycholic acid play common and distinct roles in HCT116 human colon cell proliferation -
Zeng, H., Claycombe, K.J., Reindl, K.M. 2015. Butyrate and deoxycholic acid play common and distinct roles in HCT116 human colon cell proliferation [abstract]. Journal of Federation of American Societies for Experimental Biology. 29:752.4.
Methylseleninic acid sensitizes Notch3-activated OVCA429 ovarian cancer cells to carboplatin Reprint Icon -
Tzeng, T.J., Fu, Y., Zeng, H., Cheng, W. 2014. Methylseleninic acid sensitizes Notch3-activated OVCA429 ovarian cancer cells to carboplatin. PLoS One. 9(7):e101664.
Methylselenol, a selenium metabolite, inhibits colon cancer cell growth and cancer xenografts in C57BL/6 mice -
Zeng, H. 2014. Methylselenol, a selenium metabolite, inhibits colon cancer cell growth and cancer xenografts in C57BL/6 mice [abstract]. Federation of American Societies for Experimental Biology Conference. 28(1):374.2.
Mechanisms linking dietary fiber, gut microbiota and colon cancer prevention Reprint Icon -
Zeng, H., Lazarova, D.L., Bordonaro, M. 2014. Mechanisms linking dietary fiber, gut microbiota and colon cancer prevention. World Journal of Gastrointestinal Oncology. 6(2):41-51.
Dietary effects on adipocyte metabolism and epigenetics -
Claycombe, K.J., Zeng, H., Combs, G.F. 2015. Dietary effects on adipocyte metabolism and epigenetics. In: Ho, E. Domann, F. Nutrition and Epigenetics. Boca Raton, FL. CRC Press. p. 323-335.
Decreased levels of miR-224 and the passenger strand of miR-221 increase MBD2, suppressing maspin and promoting colorectal tumor growth and metastasis in mice Reprint Icon -
Yuan, K., Xie, K., Fox, J., Zeng, H., Gao, H., Huang, C., Wu, M. 2013. Decreased levels of miR-224 and the passenger strand of miR-221 increase MBD2, suppressing maspin and promoting colorectal tumor growth and metastasis in mice. Gastroenterology. 145:853–864.
Methylselenol, a selenium metabolite, modulates p53 pathway and inhibits the growth of MC-26 colon cancer xenografts in balb/c mice -
Zeng, H., Cheng, W., Johnson, L.K. 2012. Methylselenol, a selenium metabolite, modulates p53 pathway and inhibits the growth of MC-26 colon cancer xenografts in balb/c mice. Journal of Nutritional Biochemistry. DOI:10.1016/j.nutbio.2012.04.008.
Activation of ERK signaling and induction of colon cancer cell death by piperlongumine Reprint Icon -
Randhawa, H., Kibble, K., Zeng, H., Mayer, M.P., Reindl, K.M. 2013. Activation of ERK signaling and induction of colon cancer cell death by piperlongumine. Toxicology In Vitro. 27:1626-1633.
Fatty liver accompanies an increase in Lactobacillus species in the hind gut of C57BL/6 mice fed a high-fat diet Reprint Icon -
Zeng, H., Liu, J., Jackson, M.I., Zhao, F., Yan, L., Combs, G.F. 2013. Fatty liver accompanies an increase in Lactobacillus species in the hind gut of C57BL/6 mice fed a high-fat diet. Journal of Nutrition. doi:10.3945/jn.112.172460.
Selenium in bone health: roles in antioxidant protection and cell proliferation Reprint Icon -
Zeng, H., Cao, J.J., Combs, G.F. 2013. Selenium in bone health: roles in antioxidant protection and cell proliferation. Nutrients. 5:97-110.
Methylselenol, a selenium metabolite, inhibits colon cancer cell growth in vitro and in vivo -
Zeng, H. 2013. Methylselenol, a selenium metabolite, inhibits colon cancer cell growth in vitro and in vivo. Federation of American Societies for Experimental Biology Conference. 27:860.13.
Fatty liver accompanies an increase of Lactobacillus acidophilus in the hind gut of C57/BL mice fed a high-fat diet -
Zeng, H., Liu, J., Jackson, M.I., Yan, L., Combs, G.F. 2013. Fatty liver accompanies an increase of Lactobacillus acidophilus in the hind gut of C57/BL mice fed a high-fat diet. Federation of American Societies for Experimental Biology Conference. 27:1067.4.
S-Adenosylmethionine-dependent protein methylation Is required for expression of selenoprotein P and gluconeogenic enzymes in HepG2 human hepatocytes Reprint Icon -
Jackson, M.I., Cao, J.J., Zeng, H., Uthus, E.O., Combs, G.F. 2012. S-Adenosylmethionine-dependent protein methylation Is required for expression of selenoprotein P and gluconeogenic enzymes in HepG2 human hepatocytes. Journal of Biological Chemistry. 287(43):36455-36464.
Selenium and the regulation of cell cycle and apoptosis -
Selenium deficiency decreases antioxidative capacity and is detrimental to bone microarchitecture in mice Reprint Icon -
Cao, J.J., Gregoire, B.R., Zeng, H. 2012. Selenium deficiency decreases antioxidative capacity and is detrimental to bone microarchitecture in mice. Journal of Nutrition. 142:1526-1531.
8-oxoguanine DNA glycosylase 1-deficiency modifies allergic airway inflammation by regulating STAT6 and IL-4 in cells and in mice -
Li, G., Yuan, K., Fox, J., Gaid, M., Seeger, D., Weaver, A., Breitwieser, W., Bansal, A.K., Zeng, H., Gao, H., Wu, M. 2012. 8-oxoguanine DNA glycosylase 1-deficiency modifies allergic airway inflammation by regulating STAT6 and IL-4 in cells and in mice. Free Radicals in Biology and Medicine. 15;52(2):392-401.
Effect of dietary selenium and cancer cell xenograft on peripheral T and B lymphocytes in adult nude mice Reprint Icon -
Cheng, W., Holmstrom, A., Li, X., Wu, R.T., Zeng, H., Xiao, Z. 2012. Effect of dietary selenium and cancer cell xenograft on peripheral T and B lymphocytes in adult nude mice. Biological Trace Element Research. 146:230-235.
Methylselenol, a selenium metabolite, plays common and different roles in cancerous colon HCT116 cell and noncancerous NCM460 colon cell proliferation Reprint Icon -
Zeng, H., Briske Anderson, M.J., Wu, M., Moyer, M.P. 2012. Methylselenol, a selenium metabolite, plays common and different roles in cancerous colon HCT116 cell and noncancerous NCM460 colon cell proliferation. Nutrition and Cancer. 64(1):128-135.
Differential responses to selenomethioinine supplementation by sex and genotype in healthy adults Reprint Icon -
Combs, G.F., Jackson, M.I., Watts, J.J., Johnson, L.K., Zeng, H., Idso, J.P., Schomburg, L., Hoeg, A., Hoefig, C.S., Chiang, E.C., Waters, D.J., Tsuji, P.A., Davis, C.D., Milner, J.A. 2012. Differential responses to selenomethioinine supplementation by sex and genotype in healthy adults. British Journal of Nutrition. 107:1514-1525.
Determinants of selenium status in healthy adults Reprint Icon -
Combs, G.F., Watts, J.J., Jackson, M.I., Johnson, L.K., Zeng, H., Scheett, A.J., Uthus, E.O., Schomburg, L., Hoeg, A., Hoefig, C.S., Davis, C.D., Milner, J.A. 2011. Determinants of selenium status in healthy adults. Nutrition Journal. 10(75):1-10.
Nutritional and supranutritional levels of selenate differentially suppress prostate tumor growth in adult but not young nude mice -
Holmstrom, A., Zeng, H., Lei, K., Cheng, W., Wu, R. 2012. Nutritional and supranutritional levels of selenate differentially suppress prostate tumor growth in adult but not young nude mice. Journal of Nutritional Biochemistry. 23(9):1086-91.
Methylselenol, a selenium metabolite, plays a critical role in inhibiting colon cancer cell growth in vitro and in vivo -
Dietary selenium intake increases exon-specific DNA methylation of p53 gene in rat liver and colon mucosa -
Dietary selenomethionine intake increases exon-specific DNA methylation of p53 gene in rat liver and colon mucosa Reprint Icon -
Zeng, H., Yan, L., Cheng, W., Uthus, E.O. 2011. Dietary selenomethionine intake increases exon-specific DNA methylation of p53 gene in rat liver and colon mucosa. Journal of Nutrition. 141(8):1464-1468.
Obesity-related colon cancer: dietary factors and their mechanisms of anticancer action Reprint Icon -
Zeng, H., Lazarova, D.L. 2011. Obesity-related colon cancer: dietary factors and their mechanisms of anticancer action. Clinical and Experimental Pharmacology and Physiology. 39:161-167.
Encapsulation of selenium in chitosan nanoparticles improves selenium availability and protects cells from selenium-induced DNA damage response -
Zhang, S., Luo, Y., Zeng, H., Wang, Q., Tian, F., Song, J., Cheng, W. 2011. Encapsulation of selenium in chitosan nanoparticles improves selenium availability and protects cells from selenium-induced DNA damage response. Journal of Nutritional Biochemistry. 22(12):1137-42.
Chemical form of selenium affects its uptake, transport and glutathione peroxidase activity in the human intestinal Caco-2 cell model Reprint Icon -
Zeng, H., Jackson, M.I., Cheng, W., Combs, G.F. 2010. Chemical form of selenium affects its uptake, transport and glutathione peroxidase activity in the human intestinal Caco-2 cell model. Biological Trace Element Research. 143:1209-1218.
Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep Reprint Icon -
Nielsen, F.H., Johnson, L.K., Zeng, H. 2010. Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep. Magnesium Research. 23(4):158-68.
Obesity decreases serum selenium levels in DMBA-induced mammary tumor using Obese Zucker Rat Model -
Hakkak, R., Zeng, H., Lacher, C.P., Johnson, L.K., Korourian, S. 2011. Obesity decreases serum selenium levels in DMBA-induced mammary tumor using Obese Zucker Rat Model. Federation of American Societies for Experimental Biology Conference. 25:977.12.
Effect of dietary selenium on T cell immunity and cancer xenograft in nude mice -
Holmstrom, A., Li, X., Wu, R.T., Xiao, Z., Zeng, H., Lei, K.Y., Cheng, W. 2011. Effect of dietary selenium on T cell immunity and cancer xenograft in nude mice. Federation of American Societies for Experimental Biology Conference. 25:110.5.
Methylselenol, a selenium metabolite, plays a critical role in inhibiting colon cancer cell growth in vitro and in vivo -
Zeng, H., Briske Anderson, M.J. 2011. Methylselenol, a selenium metabolite, plays a critical role in inhibiting colon cancer cell growth in vitro and in vivo. Federation of American Societies for Experimental Biology Conference. 25:110.4.
Chemical form of selenium affects its uptake and transport in the human intestinal cell model, Caco-2 -
Zeng, H., Jackson, M.I., Cheng, W., Combs, G.F. 2011. Chemical form of selenium affects its uptake and transport in the human intestinal cell model, Caco-2. Federation of American Societies for Experimental Biology Conference. 25:786.2.
Host DNA repair proteins in response to Pseudomonas aeruginosa in lung epitehlial cells and in mice Reprint Icon -
Wu, M., Huang, H., Zhang, W., Kannan, S.H., Weaver, A., Mckibben, M., Herington, D., Zeng, H., Gao, H. 2011. Host DNA repair proteins in response to Pseudomonas aeruginosa in lung epitehlial cells and in mice. Infection and Immunity. 79(1):75-87.
Sulforaphane plays common and different roles in tumorigenic and nontumorigenic colon cell growth -
Zeng, H., Trujillo, O., Moyer, M.P., Botnen, J.H. 2010. Sulforaphane plays common and different roles in tumorigenic and nontumorigenic colon cell growth [abstract]. American Institute for Cancer Research . Poster No. 40.
Prolonged sulforaphane treatment activates survival signaling in nontumorigenic NCM460 colon cells but apoptotic signaling in tumorigenic HCT116 colon cells Reprint Icon -
Zeng, H., Trujillo, O.N., Moyer, M.P., Botnen, J.H. 2011. Prolonged sulforaphane treatment activates survival signaling in nontumorigenic NCM460 colon cells but apoptotic signaling in tumorigenic HCT116 colon cells. Nutrition and Cancer. 63(2):248-255.
The von Hippel-Lindau (VHL) tumor-suppressor gene is down-regulated by selenium deficiency in Caco-2 cells and rat colon mucosa Reprint Icon -
Uthus, E.O., Begaye, A., Ross, S., Zeng, H. 2010. The von Hippel-Lindau (VHL) tumor-suppressor gene is down-regulated by selenium deficiency in Caco-2 cells and rat colon mucosa. Biological Trace Element Research. 2011 142:223-231.
Pinto beans as a course of bioavailable selenium to support bone structure in mice -
Cao, J.J., Gregoire, B.R., Zeng, H. 2010. Pinto beans as a course of bioavailable selenium to support bone structure in mice [abstract]. Journal of Bone and Mineral Research. 25(Supplement 1).
Methylselenol, a Selenium Metabolite, Plays Common and Different Roles in Colonic Cancer and Nontumorigenic Colonic Cell Growth Reprint Icon -
Zeng, H., Briske Anderson, M.J., Moyer, M.P. 2010. Methylselenol, a Selenium Metabolite, Plays Common and Different Roles in Colonic Cancer and Nontumorigenic Colonic Cell Growth. Journal of Federation of American Societies for Experimental Biology. 24:916.5.
Prolonged Sulforaphane Treatment Activates Extracellular-Regulated Kinase 1/2 Signaling in Nontumorigenic Colon Cells but not Colon Cancer Cells Reprint Icon -
Zeng, H., Trujillo, O., Moyer, M.P., Botnen, J.H. 2010. Prolonged Sulforaphane Treatment Activates Extracellular-Regulated Kinase 1/2 Signaling in Nontumorigenic Colon Cells but not Colon Cancer Cells. Journal of Federation of American Societies for Experimental Biology. 24:928.4.
Effect of Chitosan on the Induction of DNA Damage Response by Selenium Compounds Reprint Icon -
Zhang, S., Zeng, H., Luo, Y., Wang, Q., Cheng, W. 2010. Effect of Chitosan on the Induction of DNA Damage Response by Selenium Compounds. Journal of Federation of American Societies for Experimental Biology. 24:lb251.
Methylselenol, a Selenium Metabolite, Induces Cell Cycle Arrest in G1 Phase and Apoptosis via the Extracellular-Regulated Kinase 1/2 Pathway and Other Cancer Signaling Genes Reprint Icon -
Zeng, H., Wu, M., Botnen, J.H. 2009. Methylselenol, a Selenium Metabolite, Induces Cell Cycle Arrest in G1 Phase and Apoptosis via the Extracellular-Regulated Kinase 1/2 Pathway and Other Cancer Signaling Genes. Journal of Nutrition. 139:1613-1618.
Deoxycholic Acid and Selenium Metabolite Methylselenol Exert Common and Distinct Effects on Cell Cycle, Apoptosis, and MAP Kinase Pathway in HCT116 Human Colon Cancer Cells Reprint Icon -
Zeng, H., Botnen, J.H., Briske Anderson, M.J. 2010. Deoxycholic Acid and Selenium Metabolite Methylselenol Exert Common and Distinct Effects on Cell Cycle, Apoptosis, and MAP Kinase Pathway in HCT116 Human Colon Cancer Cells. Nutrition and Cancer. 62(1):85-92.
Selenium as an Essential Micronutrient: Roles in Cell Cycle and Apoptosis Reprint Icon -
Zeng, H. 2009. Selenium as an Essential Micronutrient: Roles in Cell Cycle and Apoptosis. Molecules. 14(3):1263-1278.
High Dietary Intake of Sodium Selenite Does Not Affect Gene Mutation Frequency in Rat Colon and Liver Reprint Icon -
Zeng, H., Uthus, E.O., Ross, S., Davis, C.D. 2009. High Dietary Intake of Sodium Selenite Does Not Affect Gene Mutation Frequency in Rat Colon and Liver. Biological Trace Element Research. DOI 10.0017/s/12011-009-8348-3. Available: http://www.springerlink.com/humana+press/biochemistry.journal/12011.
Deoxycholic acid and selenium metabolite methylselenol exert common and distinct effects on cell cycle, apoptosis, and MAP kinase pathway in HCT116 human colon cancer cells Reprint Icon -
Zeng, H., Botnen, J.H., Briske Anderson, M.J. 2009. Deoxycholic acid and selenium metabolite methylselenol exert common and distinct effects on cell cycle, apoptosis, and MAP kinase pathway in HCT116 human colon cancer cells. Journal of Federation of American Societies for Experimental Biology. 23:338.8.
Genetic Determinants of Responses to Selenium Supplementation Reprint Icon -
Combs, G.F., Zeng, H., Jackson, M.I., Johnson, L.K., Hoeg, A., Schomburg, L., Davis, C.D., Milner, J.A. 2009. Genetic Determinants of Responses to Selenium Supplementation. Journal of Federation of American Societies for Experimental Biology. 23:346.3.
Differential effects of deoxycholic acid versus selenium metabolite methylselenol on cell cycle, apoptosis, and MAP kinase pathway in HCT116 human colon cancer cells -
Zeng, H., Botnen, J.H., Briske Anderson, M.J. 2009. Differential effects of deoxycholic acid versus selenium metabolite methylselenol on cell cycle, apoptosis, and MAP kinase pathway in HCT116 human colon cancer cells. American Association of Cancer Research Meeting. Published in Abstracts of Poster Presentations. No. 4.
Selenium is critical for cancer-signaling gene expression but not cell proliferation in human colon Caco-2 cells Reprint Icon -
Zeng, H., Botnen, J.H. 2008. Selenium is critical for cancer-signaling gene expression but not cell proliferation in human colon Caco-2 cells. Biofactors. 31(2007):155-164
Molecular mechanisms of cancer prevention by selenium Reprint Icon -
Zeng, H. 2008. Molecular mechanisms of cancer prevention by selenium. [abstract]. BIT Life Sciences' 1st World Cancer Congress. p. 365.
Selenium is critical for the regulation of tumor suppressor and pro-inflammatory gene expresssion in human colon Caco-2 cells Reprint Icon -
Zeng, H., Botnen, J.H. 2008. Selenium is critical for the regulation of tumor suppressor and pro-inflammatory gene expresssion in human colon Caco-2 cells. [abstract] Journal of Federation of American Societies for Experimental Biology. 22:696.2.
High dietary intake of sodium selenite does not affect gene mutation frequency in rat colon and liver Reprint Icon -
Zeng, H., Uthus, E.O., Ross, S.A., Davis, C.D. 2008. High dietary intake of sodium selenite does not affect gene mutation frequency in rat colon and liver. [abstract] Journal of Federation of American Societies for Experimental Biology. 22:146.7.
A selenium-deficient Caco-2 cell model for assessing differential incorporation of chemical or food selenium into glutathione peroxidase Reprint Icon -
Zeng, H., Botnen, J.H., Johnson, L.K. 2008. A selenium-deficient Caco-2 cell model for assessing differential incorporation of chemical or food selenium into glutathione peroxidase. Biological Trace Element Research. 123:98-108.
Selenium is critical for cancer-signaling gene expression but not cell proliferation in human colon Caco-2 cells -
Zeng, H., Botnen, J.H. 2007. Selenium is critical for cancer-signaling gene expression but not cell proliferation in human colon Caco-2 cells. In: American Association of Cancer Research Meeting, Advances in Colon Cancer Research, November 14-17, Cambridge, MA. p. A6.
Selenium as an anticancer nutrient: roles in cell proliferation and tumor cell invasion Reprint Icon -
Zeng, H., Combs, G.F. 2008. Selenium as an anticancer nutrient: roles in cell proliferation and tumor cell invasion. Journal of Nutritional Biochemistry. 19:1-7.
The von Hippel-Lindau (VHL) tumor-suppressor gene is down-regulated in Caco-2 cells incubated in low-selenium (Se) media -
Uthus, E.O., Begaye, A., Ross, S.A., Zeng, H. 2007. The von Hippel-Lindau (VHL) tumor-suppressor gene is down-regulated in Caco-2 cells incubated in low-selenium (Se) media [abstract]. Journal of Federation of American Societies for Experimental Biology. 21(5):A717.
Chemical forms of selenium affect glutatione peroxidase activity in human Caco-2 cell model -
Zeng, H., Botnen, J.H. 2007. Chemical forms of selenium affect glutatione peroxidase activity in human Caco-2 cell model [abstract]. Journal of Federation of American Societies for Experimental Biology. 21(5):A105.
Copper deficiency decreases the protein expression of Complex IV but not Complex I, II, III and V in mitochondrial respiratory chain in rat heart -
Zeng, H., Saari, J.T., Johnson, W.T. 2007. Copper deficiency decreases the protein expression of Complex IV but not Complex I, II, III and V in mitochondrial respiratory chain in rat heart [abstract]. Journal of Federation of American Societies for Experimental Biology. 21(5):A722.
Copper deficiency decreases the protein expression of Complex IV but not Complex I, II, III, or V in mitochondrial respiratory chain in rat heart -
Zeng, H., Saari, J.T., Johnson, W.T. 2007. Copper deficiency decreases complex IV but not complex I, II, III, or V in the mitochondrial respiratory chain in rat heart. Journal of Nutrition. 137:14-18.
CARDIAC NITRIC OXIDE SYNTHASES ARE ELEVATED IN DIETARY COPPER DEFICIENCY -
Saari, J.T., Wold, L.E., Duan, J., Ren, J., Carlson, H.L., Bode, A.M., Lentsch, A.B., Zeng, H., Schuschke, D.A. 2006. Cardiac nitric oxide synthases are elevated in dietary copper deficiency. Journal of Nutritional Biochemistry. doi:10.1016/j.jnutbio.2006.07.006.
THE SELENIUM METABOLITE METHYLSELENOL INHIBITS THE MIGRATION AND INVASION POTENTIAL OF HT1080 TUMOR CELLS -
Zeng, H., Briske-Anderson, M.J., Idso, J.P., Hunt, C. 2006. The selenium metabolite methylselenol inhibits the migration and invasion potential of HT1080 tumor cells. Journal of Nutrition. 136:1528-1532.
NEW FINDINGS ON PROTEIN EXPRESSION ON COPPER DEFICIENT RAT HEART WITH PROTEOMIC APPROACH -
Zeng, H., Saari, J.T. 2006. New findings on protein expression on copper deficient rat heart with proteomic approach [abstract]. FASEB J. 20(4):A553.
SELENIUM METABOLITE METHYLSELENOL INHIBITS MIGRATION AND INVASION POTENTIAL OF HT1080 TUMOR CELLS -
Zeng, H., Briske Anderson, M.J., Idso, J.P., Hunt, C. 2006. Selenium metabolite methylselenol inhibits migration and invasion potential of HT1080 tumor cells [abstract]. FASEB J. 20(5):A1011.
COPPER DEFICIENCY INCREASES FIBULIN-5 (DANCE/EVEC) BUT DECREASES CYTOCHROME C OXIDASE VIB EXPRESSION IN RAT HEART -
Zeng, H., Saari, J.T., Dahlen, G.M. 2005. Copper deficiency increases fibulin-5 (dance/evec) but decreases cytochrome c oxidase vib expression in rat heart. Inorganic Biochemistry. 100:186-91.
MECHANISTIC ASPECTS OF THE INTERACTION BETWEEN SELENIUM AND ARSENIC -
Zeng, H., Uthus, E.O., Combs, G.F. 2005. Mechanistic aspects of the interaction between selenium and arsenic. Inorganic Biochemistry. 99:1269-74.
INHIBITORY EFFECT OF PROLONGED-BUTYRATE TREATMENT ON MIGRATION AND INVASION OF HT1080 TUMOR CELLS -
Zeng, H., Briske-Anderson, M. 2005. Inhibitory effect of prolonged-butyrate treatment on migration and invasion of HT1080 tumor cells [abstract]. The Federation of American Societies for Experimental Biology Journal. 19(5):A1693.
PROLONGED BUTYRATE TREATMENT INHIBITS THE MIGRATION AND INVASION OF POTENTIAL HT1080 TUMOR CELLS -
Zeng, H., Briske Anderson, M.J. 2005. Prolonged butyrate treatment inhibits the migration and invasion of potential HT1080 tumor cells. Journal of Nutrition. 135:291-295.
INCREASED TYPE I COLLAGEN CONTENT AND DNA BINDING ACTIVITY OF A SINGLE-STRANDED CYTOSINE-RICH SEQUENCE IN THE HIGH-SALT BUFFER PROTEIN EXTRACT OF THE COPPER-DEFICIENT RAT HEART -
Zeng, H., Saari, J.T. 2004. Increased type I collagen content and DNA binding activity of a single-stranded, cytosine-rich sequence in the high-salt buffer protein extract of the copper-deficient rat heart. Journal of Nutritional Biochemistry. 15:694-99.
IRON ABSORPTION BY HETEROZYGOUS CARRIERS OF THE HFE C282Y MUTATION ASSOCIATED WITH HEMOCHROMATOSIS -
Hunt, J.R., Zeng, H. 2004. Iron absorption by heterozygous carriers of the HFE C282Y mutation associated with hemochromatosis. American Journal of Clinical Nutrition. 80:924-31.
INCREASED TYPE I COLLAGEN CONTENT AND DNA BINDING ACTIVITY OF A SINGLE-STRANDED CYTOSINE-RICH SEQUENCE IN THE NUCLEAR EXTRACT OF THE COPPER-DEFICIENT RAT HEART -
Zeng, H., Saari, J.T. 2004. Increased type I collagen content and DNA binding activity of a single-stranded cytosine-rich sequence in the nuclear extract of the copper-deficient rat heart [abstract]. The Federation of American Societies for Experimental Biology Journal. 18:A914.
HEME AND NONHEME IRON ABSORPTION IN HUMANS HETEROZYGOUS FOR THE C282Y HFE MUTATION ASSOCIATED WITH HEMOCHROMATOSIS -
Hunt, J.R., Zeng, H. 2004. Heme and nonheme iron absorption in humans heterozygous for the C282Y HFE mutation associated with hemochromatosis. Journal of Federation of American Societies for Experimental Biology. 18:A766-A767.
COPPER INHIBITION OF SELENITE-INDUCED CELL CYCLE ARREST APPEARS TO BE EXTRACELLULAR -
Zeng, H., Botnen, J.H. 2004. Copper inhibition of selenite-induced cell cycle arrest appears to be extracellular. Journal of Federation of American Societies for Experimental Biology. 18:A914.
THIOREDOXIN REDUCTASE IN HUMAN HEPATOMA CELLS IS TRANSCRIPTIONALLY REGULATED BY SULFORAPHANE AND OTHER ELECTROPHILES VIA AN ANTIOXIDANT RESPONSE ELEMENT -
Hintze, K.J., Wald, K.A., Zeng, H., Jeffery, E.H., Finley, J.W. 2003. Thioredoxin reductase by sulforaphane and other electrophiles via an antioxidant response element. Journal of Nutrition. 133:2721-2727.
THIOREDOXIN REDUCTASE IN HUMAN HEPATOMA CELLS IS TRANSCRIPTIONALLY REGULATED BY SULFORAPHANE AND OTHER ELECTROPHILES VIA AN ANTIOXIDANT RESPONSE ELEMENT -
Hintze, K.J., Wald, K., Jeffery, E.H., Finley, J.W., Zeng, H. 2003. Thioredoxin reductase in human hepatoma cells is transcriptionally regulated by sulforaphane and other electrophiles via an antioxidant response element. Journal of Nutrition. 133:2721-2727.
DOWN-REGULATION OF PROLIFERATING CELL NUCLEAR ANTIGEN GENE EXPRESSION OCCURS DURING CELL CYCLE ARREST INDUCED BY HUMAN FECAL WATER IN COLONIC HT-29 CELLS -
Zeng, H., Davis, C.D. 2003. Down-regulation of proliferating cell nuclear antigen gene expression occurs during cell cycle arrest induced by human fecal water in colonic HT-29 cells. Journal of Nutrition. 133:2682-2687.
HEME AND NONHEME IRON ABSORPTION IN HUMANS WITH C282Y AND H63D HFE MUTATIONS ASSOCIATED WITH HEMOCHROMATOSIS -
Hunt, J.R., Zeng, H. 2003. Heme and nonheme iron absorption in humans with the C282Y and H63D mutations associated with hemochromatosis [abstract]. BioIron 2003 Symposium, May 4-9, 2003, Washington, D.C. Abstract #62. p.166.
COPPER MAY INTERACT WITH SELENITE EXTRACELLULARLY IN CULTURED HT-29 CELLS -
Zeng, H. and Botnen, J.H. 2004. Copper may interact with selenite extracellularly in cultured HT-29 cells. Journal of Nutritional Biochemistry. 15:179-184.
GENOMIC AND PROTEOMIC TECHNIQUES AND THEIR APPLICATION IN SELENIUM RESEARCH -
Zeng, H. 2003. Genomic and proteomic techniques and their application in selenium research. Current Pharmacogenomics. 1:59-65.
IMPACT OF ESTROGEN REPLACEMENT ON VENTRICULAR MYOCYTE CONTRACTILE FUNCTION AND PROTEIN KINASE B/AKT ACTIVATION -
Ren, J., Kinze, K., Roughead, Z.K., Duan, J., Colligan, P.B., Ren, B.H., Lee, K.J., Zeng, H. 2003. Impact of estrogren replacement on ventricular myocyte contractile function and protein kinase B/AKT activation. American Journal of Physiology. 284:H1800-H1807.
EFFECT OF SELENIUM-ENRICHED BROCCOLI DIET ON DIFFERENTIAL GENE EXPRESSION IN MIN MOUSE LIVER -
Zeng, H., Davis, C.D., Finley, J.W. 2003. Effect of selenium-enriched broccoli diet on differential gene expression in min mouse liver [abstract]. Journal of Federation of American Societies for Experimental Biology. 17(5):A1159.
THE MOLECULAR BASIS OF SELENITE/SELENO-METHIONINE AT PHYSIOLOGICAL CONCENTRATIONS IN PROMOTION OF HL-60 CELL CYCLE PROGRESSION -
Zeng, H. 2002. The molecular basis of selenite/seleno-methionine at physiological concentrations in promotion of HL-60 cell cycle progression [abstract]. The Federation of American Societies for Experimental Biology Journal. 16:A264.
SELENITE AND SELENOMETHIONINE PROMOTE HL-60 CELL CYCLE PROGRESSION -
Zeng, H. 2002. Selenite and selenomethionine promote HL-60 cell cycle progression. Journal of Nutrition. 132:674-679.
HEME AND NONHEME IRON ABSORPTION BY HUMANS WITH THE C282Y AND H63D HFE MUTATIONS ASSOCIATED WITH HEMOCHROMATOSIS -
Hunt, J.R., Zeng, H. 2002. Heme and nonheme iron absorption by humans with the C282Y and H63D HFE mutations associated with hemochromatosis [abstract]. The Federation of American Societies for Experimental Biology Journal. 16:A22.
SELENIUM-ENRICHED BROCCOLI DECREASES INTESTINAL TUMORIGENESIS IN MULTIPLE INTESTINAL NEOPLASIA (MIN) MICE -
Davis, C.D., Zeng, H., Finley, J.W. 2002. Selenium-enriched broccoli decreases intestinal tumorigenesis in multiple intestinal neoplasia (Min) mice. Journal of Nutrition. 132:307-309.
ARSENIC SUPPRESSES NECROSIS INDUCED BY SELENITE IN HUMAN LEUKEMIA HL-60 CELLS -
Zeng, H. 2001. Arsenic suppresses necrosis induced by selenite in human leukemia HL-60 cells. Biological Trace Element Research. 83:1-15.
THE EFFECT OF ARSENIC ON THE SELENIUM-INDUCED CELL DEATH PATHWAY -
Zeng, H. 2001. The effect of arsenic on the selenium-induced cell death pathway [abstract]. The Federation of American Societies for Experimental Biology Journal. 15:A604.
Last Modified: 8/26/2016
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