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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Ruminant Diseases and Immunology Research » People & Locations » Timothy Reinhardt (Tim)
Timothy A Reinhardt (Tim)
Ruminant Diseases and Immunology Research
Research Animal Scientist

Phone: (515) 337-7540
Fax: (515) 337-7149
Room 1135

1920 DAYTON AVE
AMES , IA 50010
Projects
Non-antibiotic Approaches to Control Mastitis
In-House Appropriated (D)
  Accession Number: 432018

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Differential phenotype of immune cells in blood and milk following pegylated granulocyte colony stimulating factor (PEG-gCSF) therapy during a chronic Staphylococcus aureus infection in lactating Holsteins -
Synthetic bovine NK-lysin-derived peptide (bNK2A) does not require intra-chain disulfide bonds for bactericidal activity -
Dassanayake, R.P., Falkenberg, S.M., Nicholson, E.M., Briggs, R.E., Tatum, F.M., Sharma, V.K., Reinhardt, T.A. 2019. Synthetic bovine NK-lysin-derived peptide (bNK2A) does not require intra-chain disulfide bonds for bactericidal activity. PLoS One. 14(6). https://doi.org/10.1371/journal.pone.0218507.
Milk biosynthesis requires TMEM165, a Golgi cation exchanger -
Avian intestinal mucus modulates Campylobacter jejuni gene expression in a host-specific manner -
Looft, T.P., Cai, G., Choudhury, B., Lai, L.X., Lippolis, J.D., Reinhardt, T.A., Sylte, M.J., Casey, T.A. 2019. Avian intestinal mucus modulates Campylobacter jejuni gene expression in a host-specific manner. Frontiers in Microbiology. 9:3215. https://doi.org/10.3389/fmicb.2018.03215.
Membrane and cytoplasmic proteins of Mycobacterium avium subspecies paratuberculosis that bind to novel monoclonal antibodies -
Bannantine, J.P., Stabel, J.R., Lippolis, J.D., Reinhardt, T.A. 2018. Membrane and cytoplasmic proteins of Mycobacterium avium subspecies paratuberculosis that bind to novel monoclonal antibodies. Microorganisms. 11;6(4). https://doi.org/10.3390/microorganisms6040127.
Vitamin D status and responses in dairy cows naturally infected with Mycobacterium avium subsp. paratuberculosis -
Stabel, J.R., Reinhardt, T.A., Hempel, R.J. 2018. Vitamin D status and responses in dairy cows naturally infected with Mycobacterium avium subsp. paratuberculosis. Journal of Dairy Science. 102:1594-1600. https://doi.org/10.3168/jds.2018-15241.
Effects of vitamin D3 on macrophages from cows naturally infected with Mycobacterium avium subsp. paratuberculosis -
Symposium review: Omics in dairy and animal science--Promise, potential, and pitfalls -
Lippolis, J.D., Powell, E.J., Reinhardt, T.A., Thacker, T.C., Casas, E. 2019. Symposium review: Omics in dairy and animal science-Promise, potential, and pitfalls. Journal of Dairy Science. 102(5):4741-4754. https://doi.org/10.3168/jds.2018-15267.
Antimicrobial activity of bovine NK-lysin-derived peptides on Mycoplasma bovis -
Dassanayake, R.P., Falkenberg, S.M., Register, K.B., Samorodnitsky, D., Nicholson, E.M., Reinhardt, T.A. 2018. Antimicrobial activity of bovine NK-lysin-derived peptides on Mycoplasma bovis. PLoS One. 13(5):e0197677. https://doi.org/10.1371/journal.pone.0197677.
The effect of pegylated granulocyte colony stimulating factor therapy against experimental mastitis in lactating Holsteins -
Powell, E.J., Reinhardt, T.A., Casas, E., Lippolis, J.D. 2018. The effect of pegylated granulocyte colony-stimulating factor therapy against experimental mastitis in lactating Holsteins. Journal of Dairy Science. 101(9):8182-8193. https://doi.org/10.3168/jds.2018-14550.
Genomic and transcriptomic analysis of Escherichia coli strains associated with persistent and transient bovine mastitis and the role of colanic acid -
Lippolis, J.D., Holman, D.B., Brunelle, B.W., Thacker, T.C., Bearson, B.L., Reinhardt, T.A., Sacco, R.E., Casey, T. 2017. Genomic and transcriptomic analysis of Escherichia coli strains associated with persistent and transient bovine mastitis and the role of colanic acid. Infection and Immunity. 86(1):e00566-17. https://doi.org/10.1128/IAI.00566-17.
Genome sequences of Escherichia coli strains that cause persistent and transient mastitis -
Thacker, T.C., Lippolis, J.D., Brunelle, B.W., Casey, T., Reinhardt, T.A., Sacco, R.E., Holman, D.B. 2017. Genome sequences of Escherichia coli strains that cause persistent and transient mastitis. Genome Announcements. 5(34):e00775-17. https://doi.org/10.1128/genomeA.00775-17.
Vitamin D status of dairy cattle: Outcomes of current practices in the dairy industry Reprint Icon -
Nelson, C.D., Lippolis, J.D., Reinhardt, T.A., Sacco, R.E., Powell, T.L., Drewnoski, M.E., O'Neill, M., Beitz, D.C., Weiss, W.P. 2016. Vitamin D status of dairy cattle: Outcomes of current practices in the dairy industry. Journal of Dairy Science. 99:10150-10160.
Differential gene expression of three mastitis-causing Escherichia coli strains grown under planktonic, swimming, and swarming culture conditions Reprint Icon -
Lippolis, J.D., Brunelle, B.W., Reinhardt, T.A., Sacco, R.E., Thacker, T.C., Looft, T.P., Casey, T. 2016. Differential gene expression of three mastitis-causing Escherichia coli strains grown under planktonic, swimming, and swarming culture conditions. mSystems. 1(4):e00064-16.
Tumoral vitamin D synthesis by CYP27B1 1-alpha-hydroxylase delays mammary tumor progression in the PyMT-MMTV mouse model and its action involves NF-kappaB modulation Reprint Icon -
Li, J., Luco, A., Ochietti, B., Fadhil, I., Camirand, A., Reinhardt, T.A., St-Arnaud, R., Muller, W., Kremer, R. 2016. Tumoral vitamin D synthesis by CYP27B1 1-alpha-hydroxylase delays mammary tumor progression in the PyMT-MMTV mouse model and its action involves NF-kappaB modulation. Endocrinology. doi: 10.1210/en.2015-1824.
Parainfluenza virus 3 blocks antiviral mediators downstream of the interferon lambda receptor by modulating stat1 phosphorylation Reprint Icon -
Eberle, K.C., McGill, J.L., Reinhardt, T.A., Sacco, R.E. 2016. Parainfluenza virus 3 blocks antiviral mediators downstream of the interferon lambda receptor by modulating stat1 phosphorylation. Journal of Virology. 90:2948-2958. doi:10.1128/JVI.02502-15.
Effects of fractionated colostrum replacer and vitamins A, D, and E on haptoglobin and clinical health in neonatal Holstein calves challenged with Mycobacterium avium ssp. paratuberculosis Reprint Icon -
Krueger, L.A., Reinhardt, T.A., Beitz, D.C., Stuart, R.L., Stabel, J.R. 2016. Effects of fractionated colostrum replacer and vitamins A, D, and E on haptoglobin and clinical health in neonatal Holstein calves challenged with Mycobacterium avium ssp. paratuberculosis. Journal of Dairy Science. 99(4):2884-95. doi: 10.3168/jds.2015-10395.
Composition and potency characterization of Mycobacterium avium subsp. paratuberculosis purified protein derivatives Reprint Icon -
Capsel, R.T., Thoen, C.O., Reinhardt, T.A., Lippolis, J.D., Olsen, R., Stabel, J.R., Bannantine, J.P. 2016. Composition and potency characterization of Mycobacterium avium subsp. paratuberculosis purified protein derivatives. Veterinary Microbiology. 11(5):e0154685. doi: 10.1371/journal.pone.0154685.
MicroRNA expression profiles of bovine milk exosomes in response to Staphylococcus aureus infection -
Sun, J., Aswath, K., Schroeder, S.G., Lippolis, J.D., Reinhardt, T.A., Sonstegard, T.S. 2015. MicroRNA expression profiles of bovine milk exosomes in response to Staphylococcus aureus infection. Biomed Central (BMC) Genomics. 16:806.
ZAP-70, CTLA-4, and proximal T cell receptor signaling in cows infected with Mycobacterium avium subsp. paratuberculosis -
Leite, F.L., Eslabao, L.B., Pesch, B.A., Bannantine, J.P., Reinhardt, T.A., Stabel, J.R. 2015. ZAP-70, CTLA-4, and proximal T cell receptor signaling in cows infected with Mycobacterium avium subsp. paratuberculosis. Veterinary Immunology and Immunopathology. 167(1-2):15-21. doi: 10.1016/j.vetimm.2015.06.017.
Effect of feeding 25-hydroxyvitamin D3 with a negative cation-anion difference diet on calcium and vitamin D status of periparturient cows and their calves Reprint Icon -
Weiss, W.P., Azem, E., Steinberg, W., Reinhardt, T.A. 2015. Effect of feeding 25-hydroxyvitamin D3 with a negative cation-anion difference diet on calcium and vitamin D status of periparturient cows and their calves. Journal of Dairy Science. 98(8):5588-5600. doi:10.3168/jds.2014-9188.
Seasonal variation in vitamin D status of beef cattle reared in the central United States Reprint Icon -
Casas, E., Lippolis, J.D., Kuehn, L.A., Reinhardt, T.A. 2015. Seasonal variation in vitamin D status of beef cattle reared in the central United States. Domestic Animal Endocrinology. 52:71-74. DOI: 10.1016/j.domaniend.2015.03.003.
Chemoprevention activity of 25-hydroxyvitamin D in the MMTV-PyMT mouse model of breast cancer Reprint Icon -
Rossdeutscher, A., Li, J., Luco, A., Fadhil, I., Ochietti, B., Camirand, A., Huang, D., Reinhardt, T.A., Muller, W., Kremer, R. 2015. Chemoprevention activity of 25-hydroxyvitamin D in the MMTV-PyMT mouse model of breast cancer. Cancer Prevention Research. 8(2):120-128. DOI: 10.1158/1940-6207.CAPR-14-0110.
Envelope protein complexes of Mycobacterium avium subsp. paratuberculosis and their antigenicity Reprint Icon -
Leite, F.L., Reinhardt, T.A., Bannantine, J.P., Stabel, J.R. 2015. Envelope protein complexes of Mycobacterium avium subsp. paratuberculosis and their antigenicity. Veterinary Microbiology. 175(2-4):275-285.
Proteomic analysis reveals protein expression differences in Escherichia coli strains associated with persistent versus transient mastitis Reprint Icon -
Lippolis, J.D., Brunelle, B.W., Reinhardt, T.A., Sacco, R.E., Nonnecke, B.J., Dogan, B., Simpson, K., Schukken, Y. 2014. Proteomic analysis reveals protein expression differences in Escherichia coli strains associated with persistent versus transient mastitis. Journal of Proteomics. 108:373-381. DOI: 10.1016/j.jprpt.2014.06.008.
Acute phase response elicited by experimental bovine diarrhea virus (BVDV) infection is associated with decreased vitamin D and E status of vitamin-replete preruminant calves Reprint Icon -
Nonnecke, B.J., McGill, J.L., Ridpath, J.F., Sacco, R.E., Lippolis, J.D., Reinhardt, T.A. 2014. Acute phase response elicited by experimental bovine diarrhea virus (BVDV) infection is associated with decreased vitamin D and E status of vitamin-replete preruminant calves. Journal of Dairy Science. 97(9):5566-5579. DOI: 10.3168/jds.2014-8293.
MicroRNA content in milk exosomes as a phenotypic indicator of Staphylococcus aureus infection in the bovine mammary gland -
Jiajie, S., Kshama, A., Schroeder, S.G., Reinhardt, T.A., Lippolis, J.D., Sonstegard, T.S. 2014. MicroRNA content in milk exosomes as a phenotypic indicator of Staphylococcus aureus infection in the bovine mammary gland. BARC Poster Day, Poster 61, pp. 73.
Computational analysis of bovine milk exosomal miRNAs profiles derived from uninfected and Streptococcus uberis infected mammary gland -
Aswath, K., Jiajie, S., Schroeder, S.G., Reinhardt, T.A., Lippolis, J.D., Sonstegard, T.S. 2014. Computational analysis of bovine milk exosomal miRNAs profiles derived from uninfected and Streptococcus uberis infected mammary gland. BARC Poster Day, Poster 62, pp. 74.
Envelope protein complexes of Mycobacterium avium subsp. paratuberculosis and their antigenicity -
Leite, F.L., Reinhardt, T.A., Bannantine, J.P., Stabel, J.R. 2014. Envelope protein complexes of Mycobacterium avium subsp. paratuberculosis and their antigenicity [abstract]. International Colloquium on Paratuberculosis. p. 32.
ZAP-70, CTLA-4 and proximal T cell receptor signaling in cows infected with Mycobacterium avium subsp. paratuberculosis -
Leite, F.L., Eslabao, L.B., Pesch, B.A., Bannantine, J.P., Reinhardt, T.A., Stabel, J.R. 2014. ZAP-70, CTLA-4 and proximal T cell receptor signaling in cows infected with Mycobacterium avium subsp. paratuberculosis [abstract]. International Colloquium on Paratuberculosis. p. 144.
The Ca2+/H+ antiporter TMEM165 expression, localization in the developing, lactating and involuting mammary gland parallels the secretory pathway Ca2+ATPase (SPCA1) Reprint Icon -
Reinhardt, T.A., Lippolis, J.D., Sacco, R.E. 2014. The Ca2+/H+ antiporter TMEM165 expression, localization in the developing, lactating and involuting mammary gland parallels the secretory pathway Ca2+ATPase (SPCA1). Biochemical and Biophysical Research Communications. 445(2):417-421.
MicroRNA regulation of bovine monocyte inflammatory and metabolic networks in an in vivo infection model Reprint Icon -
Lawless, N., Reinhardt, T.A., Bryan, K., Baker, M., Pesch, B.A., Zimmerman, D.R., Zuelke, K.A., Sonstegard, T.S., O'Farrelly, C., Lippolis, J.D., Lynn, D.J. 2014. MicroRNA regulation of bovine monocyte inflammatory and metabolic networks in an in vivo infection model. Genes, Genomes, Genetics. 4(6):957-971. DOI: 10.1534/g3.113.009936.
Seasonal variation in vitamin D status of beef cattle reared in the midwest and Fed to NRC recommendations. -
Cellular calcium dynamics in lactation and breast cancer: From physiology to pathology Reprint Icon -
Cross, B.M., Breitwieser, G.E., Reinhardt, T.A., Rao, R. 2014. Cellular calcium dynamics in lactation and breast cancer: From physiology to pathology. American Journal of Physiology - Cell Physiology. 306(6):C515-C526.
Neonatal calf infection with respiratory syncytial virus: drawing parallels to the disease in human infants -
Sacco, R.E., McGill, J.L., Palmer, M.V., Lippolis, J.D., Reinhardt, T.A., Nonnecke, B.J. 2014. Neonatal calf infection with respiratory syncytial virus: drawing parallels to the disease in human infants. In: Rosenberg, H.F., Domachowske, J.B., editors. Pneumoviruses and Metapneumoviruses. Basel, Switzerland: MDPI AG. p. 46-69.
Proteomic differences between Escherichia coli strains that cause transient versus persistent intramammary infections [abstract] -
SPCA2 regulates Orai1 trafficking and store independent Ca2+ entry in a model of lactation Reprint Icon -
Cross, B.M., Hack, A., Reinhardt, T.A., Rao, R. 2013. SPCA2 regulates Orai1 trafficking and store independent Ca2+ entry in a model of lactation. PLoS One. 8(6):e67348.
A genome-wide association study identified CYP2J2 as a major gene controlling serum vitamin D in beef cattle Reprint Icon -
Casas, E., Leach, R.J., Reinhardt, T.A., Thallman, R.M., Lippolis, J.D., Bennett, G.L., Kuehn, L.A. 2013. A genome-wide association study identified CYP2J2 as a major gene controlling serum vitamin D in beef cattle. Journal of Animal Science. 91:3549-3556.
A genome-wide association study identified CYP2J2 as a major gene controlling serum Vitamin D status in beef cattle -
Casas, E., Leach, R.J., Reinhardt, T.A., Thallman, R.M., Lippolis, J.D., Bennett, G.L., Kuehn, L.A. 2013. A genome-wide association study identified CYP2J2 as a major gene controlling serum Vitamin D status in beef cattle. Journal of Animal Science Supplement. Vol.91(Supplement 2):62.Abstract No. 0185.
Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis Reprint Icon -
Reinhardt, T.A., Sacco, R.E., Nonnecke, B.J., Lippolis, J.D. 2013. Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis. Journal of Proteomics. 82:141-154.
Differential chemokine and cytokine production by neonatal bovine gamma delta T-cell subsets in response to viral toll-like receptor agonists and in vivo respiratory syncytial virus infection Reprint Icon -
McGill, J.L., Nonnecke, B.J., Lippolis, J.D., Reinhardt, T.A., Sacco, R.E. 2013. Differential chemokine and cytokine production by neonatal bovine gamma delta T-cell subsets in response to viral toll-like receptor agonists and in vivo respiratory syncytial virus infection. Immunology. 139(2):227-244.
Neonatal calf infection with respiratory syncytial virus: drawing parallels to the disease in human infants -
Sacco, R.E., McGill, J.L., Palmer, M.V., Lippolis, J.D., Reinhardt, T.A., Nonnecke, B.J. 2012. Neonatal calf infection with respiratory syncytial virus: drawing parallels to the disease in human infants. Viruses. 4(12):3731-3753.
Vitamin D signaling in the bovine immune system: A model for understanding human vitamin D requirements -
Nelson, C.D., Reinhardt, T.A., Lippolis, J.D., Sacco, R.E., Nonnecke, B.J. 2012. Vitamin D signaling in the bovine immune system: A model for understanding human vitamin D requirements. Nutrients. 4(3):181-196.
Differential expression of cytokines in response to respiratory syncytial virus infection of calves with high or low circulating 25-hydroxyvitamin D3 -
Sacco, R.E., Nonnecke, B.J., Palmer, M.V., Waters, W.R., Lippolis, J.D., Reinhardt, T.A. 2012. Differential expression of cytokines in response to respiratory syncytial virus infection of calves with high or low circulating 25-hydroxyvitamin D3. PLoS One. 7(3):e33074. Available: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0033074.
Bovine milk exosome proteome -
Reinhardt, T.A., Lippolis, J.D., Nonnecke, B.J., Sacco, R.E. 2012. Bovine milk exosome proteome. Journal of Proteomics. 75(5):1486-1492.
Treatment of an intramammary bacterial infection with 25-hydroxyvitamin D3 -
Lippolis, J.D., Reinhardt, T.A., Sacco, R.E., Nonnecke, B.J., Nelson, C.D. 2011. Treatment of an intramammary bacterial infection with 25-hydroxyvitamin D3. PLoS One. 6(10):e25479. Available: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184989/pdf/pone.0025479.pdf.
Innate immune response to a bovine mastitis pathogen profiled in milk and blood monocytes using a systems biology approach -
Regulation of Mycobacterium-specific mononuclear cell responses by 25-hydroxyvitamin D3 -
Nelson, C.D., Nonnecke, B.J., Reinhardt, T.A., Waters, W.R., Beitz, D.C., Lippolis, J.D. 2011. Regulation of Mycobacterium-specific mononuclear cell responses by 25-hydroxyvitamin D3. PLoS One. 6(6):e21674. Available: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0021674.
Utility, Limitations, and Promise of Proteomics in Animal Science -
Lippolis, J.D., Reinhardt, T.A. 2010. Utility, limitations, and promise of proteomics in animal science. Veterinary Immunology and Immunopathology. 138(4):241-251.
In vivo activation of the intracrine vitamin D pathway in innate immune cells and mammary tissue during a bacterial infection -
Nelson, C.D., Reinhardt, T.A., Beitz, D.C., Lippolis, J.D. 2010. In vivo activation of the intracrine vitamin D pathway in innate immune cells and mammary tissue during a bacterial infection. PLoS One. 5(11):e15469. Available: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0015469.
Methods and Approaches to Mass Spectroscopy Based Protein Identification -
Lippolis, J.D., Reinhardt, T.A. 2011. Methods and approaches to mass spectroscopy based protein identification. In: Whitfield, P.D. Eckersall, D., editors. Methods in animal proteomics. West Sussex, UK: Wiley-Blackwell. p. 77-102.
Prevalence of Subclinical Hypocalcemia in Dairy Herds -
Reinhardt, T.A., Lippolis, J.D., Mccluskey, B.J., Goff, J.P., Horst, R.L. 2011. Prevalence of Subclinical Hypocalcemia in Dairy Herds. The Veterinary Journal. 188:122-124.
1,25-Dihydroxyvitamin D3 Enhances Innate Immune Responses of Bovine Mammary Epithelial Cells that are Triggered by Toll-like Receptor Signaling -
Nelson, C.D., Reinhardt, T.A., Beitz, D.C., Lippolis, J.D. 2010. 1,25-Dihydroxyvitamin D3 Enhances Innate Immune Responses of Bovine Mammary Epithelial Cells that are Triggered by Toll-like Receptor Signaling [abstract]. Midwest Branch of the American Dairy Science Association. p. 30.
Vitamin D Signaling in the Bovine Mammary Gland is Part of the Innate Immune Response to Bacterial Pathogens -
Nelson, C.D., Reinhardt, T.A., Lippolis, J.D. 2010. Vitamin D Signaling in the Bovine Mammary Gland is Part of the Innate Immune Response to Bacterial Pathogens [abstract]. National Mastitis Council. p. 196.
Modulation of the Bovine Innate Immune Response by Production of 1alpha,25-Dihydroxyvitamin D3 in Bovine Monocytes Reprint Icon -
Nelson, C.D., Reinhardt, T.A., Thacker, T.C., Beitz, D.C., Lippolis, J.D. 2010. Modulation of the Bovine Innate Immune Response by Production of 1alpha,25-Dihydroxyvitamin D3 in Bovine Monocytes. Journal of Dairy Science. 93(3):1041-1049.
Improvement of the Innate Immune Response of Bovine Monocytes Via an Intracrine Vitamin D Signaling Pathway -
Nelson, C.D., Reinhardt, T.A., Beitz, D.C., Lippolis, J.D. 2009. Improvement of the Innate Immune Response of Bovine Monocytes Via an Intracrine Vitamin D Signaling Pathway [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 94.
Short Communication: The Preruminant Calf as a Model for Characterizing the Effects of Vitamin D Status in the Neonate -
Nonnecke, B.J., Reinhardt, T.A., Waters, W.R. 2009. Short Communication: The Preruminant Calf as a Model for Characterizing the Effects of Vitamin D Status in the Neonate. Journal of Dairy Science. 92(11):5692-5696.
Expression of Inducible Nitric Oxide Synthase is Up-Regulated by Production of 1,25-Dihydroxyvitamin D3 in Bovine Monocytes in Response to Toll-Like Receptor Signaling -
Nelson, C.D., Beitz, D.C., Reinhardt, T.A., Lippolis, J.D. 2009. Expression of Inducible Nitric Oxide Synthase is Up-Regulated by Production of 1,25-Dihydroxyvitamin D3 in Bovine Monocytes in Response to Toll-Like Receptor Signaling [abstract]. American Dairy Science Association. Paper No. 84.
Proteomics of mastitis causing Escherichia coli -
Lippolis, J.D., Reinhardt, T.A., Kehrli Jr, M.E. 2009. Proteomics of mastitis causing Escherichia coli. Proceedings of National Mastitis Council. 48:236-237.
Mammary gland involution is associated with rapid down regulation of major mammary Ca**2+-ATPases -
Reinhardt, T.A., Lippolis, J.D. 2009. Mammary gland involution is associated with rapid down regulation of major mammary Ca**2+-ATPases. Biochemical and Biophysical Research Communications. 378(1):99-102.
Vitamin D Status and Its Relationship to Body Fat, Final Height, and Peak Bone Mass in Young Women -
Kremer, R., Campbell, P.P., Reinhardt, T.A., Gilsanz, V. 2009. Vitamin D Status and Its Relationship to Body Fat, Final Height, and Peak Bone Mass in Young Women. Journal of Clinical Endocrinology and Metabolism. 94(1):67-73.
Proteomic changes in Escherichia coli when grown in fresh milk versus laboratory media -
Lippolis, J.D., Bayles, D.O., Reinhardt, T.A. 2009. Proteomic changes in Escherichia coli when grown in fresh milk versus laboratory media. Journal of Proteome Research. 8(1):149-158.
Vitamin D delays breast cancer progression in the PyVMT transgenic mouse model: local conversion of the precursor 25(OH)D3 into 1,25(OH)2D3 is safer and more effective than systemic administration of 1,25(OH)2D3 -
Rossdeutscher, L., Huang, D., Li, J., Reinhardt, T.A., Muller, W., Kremer, R. 2008. Vitamin D delays breast cancer progression in the PyVMT transgenic mouse model: local conversion of the precursor 25(OH)D3 into 1,25(OH)2D3 is safer and more effective than systemic administration of 1,25(OH)2D3 [abstract]. Journal of Bone and Mineral Research. 23(abstracts supplement):S53.
Vitamin D status in young women is strongly negatively related to body weight, body mass index and body fat, but is not associated to bone mass -
Kremer, R., Campbell, P., Reinhardt, T.A., Gilsanz, V. 2008. Vitamin D status in young women is strongly negatively related to body weight, body mass index and body fat, but is not associated to bone mass [abstract]. Journal of Bone and Mineral Research. 23(abstracts supplement):S290.
Serum 25-Hydroxvitamin D Concentrations in Captive and Free-Ranging, White-Tailed Deer (Odocoileus virginianus) -
Waters, W.R., Nonnecke, B.J., Gibbs, S.E., Yabsley, M.J., Schmitt, S.M., Cosgrove, M.K., Palmer, M.V., Thacker, T.C., Olsen, S.C., Horst, R.L., Reinhardt, T.A. 2009. Serum 25-Hydroxvitamin D Concentrations in Captive and Free-Ranging, White-Tailed Deer (Odocoileus virginianus). International Journal for Vitamin and Nutrition Research. 79(3):180-187.
Vitamin D status in young women and its relationship to body fat, final height and peak bone mass -
Metabolic alkalosis transition in renal proximal tubule cells facilitates an increase in CYP27B1, while blunting responsiveness to PTH -
Forster, M.A., Masilamani, S., Reinhardt, T.A., Beckman, M.J. 2008. Metabolic alkalosis transition in renal proximal tubule cells facilitates an increase in CYP27B1, while blunting responsiveness to PTH [abstract]. Journal of Bone and Mineral Research. 23(abstracts supplement):S422.
The promise of proteomics in animal science -
Lippolis, J.D., Reinhardt, T.A. 2008. The promise of proteomics in animal science [abstract]. 2008 Joint Annual Meeting of the American Dairy Science Association/American Society of Animal Science, July 7-11, 2008, Indianapolis, Indiana. 2008 CD-ROM.
Centennial Paper: Proteomics in animal science -
Lippolis, J.D., Reinhardt, T.A. 2008. Centennial Paper: Proteomics in animal science. Journal of Animal Science. 86(9):2430-2441.
Developmental changes in the milk fat globule membrane proteome during the transition from colostrum to milk -
Reinhardt, T.A., Lippolis, J.D. 2008. Developmental changes in the milk fat globule membrane proteome during the transition from colostrum to milk. Journal of Dairy Science. 91(6):2307-2318.
Toll-like receptor signaling increases production of 1,25-dihydroxyvitamin D3 in bovine macrophages -
Nelson, C.D., Beitz, D.C., Reinhardt, T.A., Lippolis, J.D. 2008. Toll-like receptor signaling increases production of 1,25-dihydroxyvitamin D3 in bovine macrophages [abstract). Experimental Biology 2008. p. 188.
Autocrine signaling mechanism of vitamin D in the bovine innate immune response -
Nelson, C.D., Beitz, D.C., Reinhardt, T.A., Lippolis, J.D. 2008. Autocrine signaling mechanism of vitamin D in the bovine innate immune response [abstract]. 2008 American Dairy Science Association, American Society of Animal Science, Midwestern Section, Annual Meeting. p. 37.
Adaptive changes in protein expression in Escherichia coli as a consequence of growth in milk -
Lippolis, J.D., Reinhardt, T.A. 2007. Adaptive changes in protein expression in Escherichia coli as a consequence of growth in milk [abstract]. Conference of Research Workers in Animal Diseases. p. 123.
Developmental changes in the milk fat globule membrane proteome during the transition from colostrum to milk -
Reinhardt, T.A. 2007. Developmental changes in the milk fat globule membrane proteome during the transition from colostrum to milk [abstract]. International Symposium on Milk Genomics and Human Health. p. 15-16.
Developmental changes in milk fat globule membrane proteome expression during the transition from colostrum to milk -
Reinhardt, T.A., Lippolis, J.D. 2007. Developmental changes in milk fat globule membrane proteome expression during the transition from colostrum to milk [abstract]. 2007 Joint Meeting-American Dairy Science Association, Poultry Science Association, Asociacion Mexicana de Produccion Animal, American Society of Animal Sciences. p. 58.
Changes in protein expression in Escherichia coli as a consequence of growth in milk whey -
Lippolis, J.D., Reinhardt, T.A. 2007. Changes in protein expression in Escherichia coli as a consequence of growth in milk whey [abstract]. 2007 Joint Meeting-American Dairy Science Association, Poultry Science Association, Asociacion Mexicana de Produccion Animal, American Society of Animal Sciences. p. 8.
Proteome and Differential Expression Analysis of Membrane and Cytosolic Proteins from Mycobacterium avium subsp. paratuberculosis Strains K-10 and 187. -
Radosevich, T.J., Reinhardt, T.A., Lippolis, J.D., Bannantine, J.P., Stabel, J.R. 2007. Proteome and Differential Expression Analysis of Membrane and Cytosolic Proteins from Mycobacterium avium subsp. paratuberculosis Strains K-10 and 187. Journal of Bacteriology. 189(3):1109-1117.
CHARACTERIZATION OF A FACTOR FROM BOVINE INTESTINE THAT PROTECTS AGAINST CRYPTOSPORIDIUM PARVUM INFECTION -
Akili, D., Heidari, M., Welter, L.M., Reinhardt, T.A., Harp, J.A. 2006. Characterization of a factor from bovine intestine that protects against Cryptosporidium parvum infection. Veterinary Parasitology. 142(1-2):168-172.
PROTEOME AND DIFFERENTIAL EXPRESSION ANALYSIS OF MEMBRANE AND CYTOSOLIC PROTEIN FROM MYCOBACTERIUM AVIUM SUBS PARATUBERCULOSIS STRAINS K10 AND 187 -
Radosevich, T.J., Stabel, J.R., Bannantine, J.P., Lippolis, J.D., Reinhardt, T.A. 2006. Proteome and Differential Expression Analysis of Membrane and Cytosolic Protein from Mycobacterium avium subs paratuberculosis Strains k10 and 187 [abstract]. American Society for Microbiology. p. 112.
NEUTROPHIL EXTRACELLULAR TRAP FORMATION BY BOVINE NEUTROPHILS IS NOT INHIBITED BY MILK -
Lippolis, J.D., Reinhardt, T.A., Goff, J.P., Horst, R.L. 2006. Neutrophil extracellular trap formation by bovine neutrophils is not inhibited by milk. Veterinary Immunology and Immunopathology. 113(1-2):248-255.
BOVINE MILK FAT GLOBULE MEMBRANE PROTEOME -
Reinhardt, T.A., Lippolis, J.D. 2006. Bovine milk fat globule membrane proteome. Journal of Dairy Research. 73(4):406-416.
BOVINE MILK FAT GLOBULE MEMBRANE PROTEOME -
Reinhardt, T.A., Lippolis, J.D. 2006. Bovine milk fat globule membrane proteome. Journal of Dairy Research. 73(4):406-416.
NEUTROPHIL EXTRACELLULAR TRAP FORMATION: AN IMPORTANT NEUTROPHIL KILLING MECHANISM THAT IS NOT INHIBITED IN MILK -
Lippolis, J.D., Reinhardt, T.A., Goff, J.P., Horst, R.L. 2006. Neutrophil extracellular trap formation: an important neutrophil killing mechanism that is not inhibited in milk [abstract]. American Dairy Science Association-American Society of Animal Science 2006 Joint Annual Meeting. p. 94.
PARTURITION AND HYPOCALCEMIA BLUNTS CALCIUM SIGNALS IN IMMUNE CELLS OF DAIRY CATTLE -
Kimura, K., Reinhardt, T.A., Goff, J.P. 2006. Parturition and hypocalcemia blunts calcium signals in immune cells of dairy cattle. Journal of Dairy Science. 89(7):2588-2595.
DIFFERENTIAL EXPRESSION ANALYSIS OF PROTEINS FROM NEUTROPHILS IN THE PERIPARTURIENT PERIOD AND NEUTROPHILS FROM DEXAMETHASONE-TREATED DAIRY COWS -
Lippolis, J.D., Peterson-Burch, B.D., Reinhardt, T.A. 2006. Differential expression analysis of proteins from neutrophils in the periparturient period and neutrophils from dexamethasone-treated dairy cows. Veterinary Immunology and Immunopathology. 111(3-4):149-164.
EXPRESSION LIBRARY IMMUNIZATION CONFERS PROTECTION AGAINST MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS INFECTION -
Huntley, J.F., Stabel, J.R., Paustian, M., Reinhardt, T.A., Bannantine, J.P. 2005. Expression Library Immunization Confers Protection against Mycobacterium avium subsp. paratuberculosis Infection. Infection and Immunity. 73(10):6877-6884.
CA2+-ADENOSINE TRIPHOSPHATASE PROTEIN EXPRESSION IN THE MAMMARY GLAND OF PERIPARTURIENT COWS -
Prapong, S., Reinhardt, T.A., Goff, J.P., Horst, R.L. 2005. Ca2+-adenosine triphosphatase protein expression in the mammary gland of periparturient cows. Journal of Dairy Science. 88(5):1741-1744.
DIFFERENTIAL EXPRESSION ANALYSIS OF IMMUNOSUPPRESSED VERSUS NORMAL NEUTROPHIL PROTEOME -
Lippolis, J.D., Reinhardt, T.A. 2005. Differential expression analysis of immunosuppressed versus normal neutrophil proteome [abstract]. American Society for Mass Spectrometry. p. 73.
ADAPTING TO THE TRANSITION BETWEEN GESTATION AND LACTATION: DIFFERENCES BETWEEN RAT, HUMAN AND DAIRY COW -
Horst, R.L., Goff, J.P., Reinhardt, T.A. 2005. Adapting to the transition between gestation and lactation: differences between rat, human and dairy cow. Journal of Mammary Gland Biology and Neoplasia. 10(2):141-156.
ENERGY AND PROTEIN EFFECTS ON THE IMMUNE SYSTEM -
Kehrli, Jr., M.E., Neill, J.D., Burvenich, C., Goff, J.P., Lippolis, J.D., Reinhardt, T.A., Nonnecke, B.J. 2006. Energy and protein effects on the immune system. In: Sejrsen, K., Hvelplund, T., Nielsen, M.O., editors. Ruminant Physiology. Wageningen, The Netherlands: Wageningen Academic Publishers. p. 455-471.
ENERGY AND PROTEIN EFFECTS ON THE IMMUNE SYSTEM -
PROTEOMIC SURVEY OF BOVINE NEUTROPHILS -
Lippolis, J.D., Reinhardt, T.A. 2005. Proteomic survey of bovine neutrophils. Veterinary Immunology and Immunopathology. 103(1-2):53-65.
NULL MUTATION IN THE GENE ENCODING PLASMA MEMBRANE CA2+-ATPASE ISOFORM 2 IMPAIRS CALCIUM TRANSPORT INTO MILK -
Reinhardt, T.A., Lippolis, J.D., Shull, G.E., Horst, R.L. 2004. Null mutation in the gene encoding plasma membrane CA2+-ATPase isoform 2 impairs calcium transport into milk. Journal of Biological Chemistry. 279(41):42369-42373.
VITAMIN D METABOLISM -
Horst, R.L., Reinhardt, T.A., Reddy, G.S. 2005. Vitamin D metabolism. In: Feldman, D., Pike, J.W., Glorieux, F.H., editors. Vitamin D. 2nd edition, Vol. I. London, UK: Elsevier Academic Press. p. 15-36.
CALCIUM PUMPS AND CALCIUM TRANSPORT IN THE MAMMARY GLAND -
Reinhardt, T.A. 2004. Calcium pumps and calcium transport in the mammary gland. Meeting Abstract.
COMPARATIVE PROTEOMIC ANALYSIS OF NORMAL AND PERIPARTURIENT BOVINE NEUTROPHILS DEMONSTRATING A REDUCTION OF MYELOPEROXIDASE DURING TRANSITION -
Lippolis, J.D., Goff, J.P., Reinhardt, T.A. 2004. Comparative proteomic analysis of normal and periparturient bovine neutrophils demonstrating a reduction of myeloperoxidase during transition [abstract]. Experimental Biology Meeting. Paper No. 776.3.
DECREASED NEUTROPHIL FUNCTION AS A CAUSE OF RETAINED PLACENTA IN DAIRY CATTLE -
Kimura, K., Goff, J.P., Kehrli Jr., M.E., Reinhardt, T.A. 2003. Decreased neutrophil function as a cause of retained placenta in dairy cattle [abstract]. ARS Immunology Research Workshop. p. 58.
USE OF MICRO ASSAY TECHNOLOGY TO COMPARE GENE EXPRESSION OF MICE INFECTED OR NOT INFECTED WITH CRYPTOSPORIDIUM PARVUM -
THE RAT ALTERNATIVELY SPLICED MRNA IS A CA2+-ATPASE AND LOCALIZED IN THE GOLGI -
DECREASED NEUTROPHIL FUNCTION AS A CAUSE OF RETAINED PLACENTA IN DAIRY CATTLE -
CHARACTERIZATION OF A FACTOR FROM BOVINE INTESTINE THAT PROTECTS AGAINST CRYPTOSPORIDIUM PARVUM INFECTION -
HYPOCALCEMIA BLUNTS IMMUNE RESPONSES DEPENDENT ON RELEASE OF INTRACELLULAR CA2+ ([CA2+]I) STORES -
ASSOCIATION BETWEEN RETAINED PLACENTA AND BLOOD INTERLEUKIN-8 CONCENTRATION AND LACK OF ASSOCIATION OF RETAINED PLACENTA WITH ENERGY AND CALCIUM METABOLIC PROFILES -
CALCITROIC ACID IS A MAJOR CATABOLIC METABOLITE IN THE METABOLISM OF 1-ALPHA-DIHYDROXYVITAMIN D2 -
PARTURITION BLUNTS CALCIUM SIGNALS IN IMMUNE CELLS -
VITAMIN D AND CALCIUM METABOLISM IN LACTATION -
DEMONSTRATION OF VITAMIN D RECEPTOR IMMUNOREACTIVITY IN OSTEOCLASTS OF HUMAN BONE -
CA2+ ATPASE PROTEIN EXPRESSION IN MAMMARY TISSUE: ALTERNATE SPLICING AND SECRETION OF PLASMA MEMBRANE CA2+ ATPASE 2BW -
CHARACTERIZATION OF VITAMIN D RECEPTOR IMMUNOREACTIVITY IN HUMAN BONE CELLS -
EXPRESSION OF CA2+ ATPASES IN BOVINE MAMMARY TISSUE AND MILK FAT MEMBRANES -
SUBCELLULAR LOCALIZATION OF CA2+ ATPASES IN LACTATING MAMMARY GLAND -
A COMPARISON OF THE RELATIVE EFFECTS OF 1,24-(OH)2D2, 1,24-(OH)2D3 AND 1,25-(OH)2D3 ON SELECTED VITAMIN D-REGULATED EVENTS IN THE RAT -
CA2+ ATPASE PROTEIN EXPRESSION IN MAMMARY TISSUE: ALTERNATE SPLICING AND SECRETION OF PLASMA MEMBRANE CA2+ ATPASE 2B -
EXPRESSION AND LOCALIZATION OF SECRETORY PATHWAY CA2+ ATPASE AND PLASMA MEMBRANE CA2+ ATPASE ISOTYPES IN BOVINE MAMMARY TISSUE DURING THE PERIPARTURIENT PERIOD -
METABOLISM OF 1,25-DIHYDROXYVITAMIN D2 BY HPK1A-RAS CELLS AND KIDNEY PERFUSION -
CA2+-ATPASE'S AND THEIR EXPRESSION IN THE MAMMARY GLAND OF PREGNANT AND LACTATING RATS -
CA2+-ATPASE PROTEIN EXPRESSION IN THE MAMMARY GLAND -
CALCITROIC ACID IS AN END PRODUCT OF 1,25-DIHYDROXYVITAMIN D2 METABOLISM -
FLOW CYTOMETRIC INTRACELLULAR IONIZED CALCIUM ANALYSIS OF IMMUNE CELLS IN PERIPARTURIENT DAIRY CATTLE -
1,25-DIHYDROXYVITAMIN D3 AND 9-CIS-RETINOIDS ARE SYNERGISTIC REGULATORS OF 24-HYDROXYLASE ACTIVITY IN THE RAT AND 1,25-DIHYDROXYVITAMIN D3 ALTERS RETINOIC ACID METABOLISM IN VIVO -
CA2+-ATPASE PROTEIN EXPRESSION IN THE MAMMARY GLAND OF PREGNANT AND LACTATING RATS -
RETINOIC ACID ENHANCES PROLIFERATIVE RESPONSES OF IL-6-DEPENDENT 7TD1.B3 CELLS IN: MANUAL OF STANDARDS FOR DIAGNOSTIC TESTS AND VACCINES, 4TH ED. PARIS: OFFICE INTL EPIZOOTIES. -
1,25-DIHYDROXYVITAMIN D3 ENHANCES MILK ANTIBODY TITERS TO ESCHERICHIA COLI J5 VACCINE -
CA2+-ATPASE'S AND THEIR EXPRESSION IN THE MAMMARY GLAND OF PREGNANT AND LACTATING RATS -
METABOLISM OF [9,11-3H]-1,25-DIHYDROXYVITAMIN D2 BY T-47D CELLS -
METABOLISM OF [9,11,3H]-1,25-DIHYDROXYVITAMIN D2 BY T-47D CELLS -
CA2+-ATPASES AND THEIR EXPRESSION IN THE MAMMARY GLAND OF PREGNANT AND LACTATING RATS -
DIETARY VITAMIN A AFFECTS THE CONCENTRATION OF VITAMIN E ASSOCIATED WITH PLASMA LIPOPROTEINS IN NEONATAL CALVES -
CA2+-ATPASE'S AND THEIR EXPRESSION IN THE MAMMARY GLAND OF PREGNANT AND LACTATING RATS -
UP-REGULATION OF CALCIUM ATPASE ISOTYPES AND 24-HYDROXYLASE IN BOVINE MAMMARY TISSUE DURING THE PERIPARTURIENT PERIOD -
PREGNANCY AND LACTATION INCREASE VITAMIN D-DEPENDENT INTESTINAL MEMBRANE CALCIUM ATPASE AND CALCIUM BINDING PROTEIN MRNA EXPRESSION -
LOCALIZATION OF 1,25-DIHYDROXYVITAMIN D RECEPTORS IN THE RAT HIPPOCAMPUS -
SELECTIVITY OF A C-TERMINAL PEPTIDE ANTISERUM FOR DIFFERENT DNA-BINDING STATES OF THE VITAMIN D RECEPTOR -
USE OF 1,25-DIHYDROXYVITAMIN D3 AS AN ADJUVANT ENHANCES ANTIBODY TITERS TO J-5 VACCINE IN THE COW -
SYNERGISM BETWEEN 1,25-DIHYDROXYVITAMIN D3 AND 9-CIS-RETINOIC ACID IN THE REGULATION OF THE RAT RENAL 24-HYDROXYLASE -
A COMPARISON OF THE RELATIVE EFFECTS OF 1,24(OH)2D2, 1,24(OH)2D3, AND 1,25(OH)2D3 ON CALCIUM METABOLISM IN THE RAT. -
REACTIVITY AND PHENOTYPE OF MONONUCLEAR LEUKOCYTES FROM NONGRAVID HEIFERS AFTER IN VITRO EXPOSURE TO 9,13-DI-CIS-RETINOIC ACID -
SYNERGISM BETWEEN 1,25-DIHYDROXYVITAMIN D3 AND 9-CIS-RETINOIC ACID IN THE REGULATION OF THE RAT RENAL 24-HYDROXYLASE -
1,25-DIHYDROXYVITAMIN D3 INHIBITS INTERFERON-GAMMA (IFN-GAMMA) SECRETION LECTIN-STIMULATED MONONUCLEAR LEUKOCYTES FROM DAIRY CATTLE -
CALCIUM AND VITAMIN D METABOLISM DURING LACTATION -
PREVENTING MILK FEVER IN DAIRY CATTLE -
ORAL ADMINISTRATION OF PUTRESCINE INHIBITS CRYPTOSPORIDIUM PARVUM INFECTIONOF NEONATAL C57BL-6 MICE AND IS INDEPENDENT OF NITRIC OXIDE SYNTHESIS -
FUNCTIONAL ASSESSMENT OF BOVINE MONOCYTES ISOLATED FROM PERIPHERAL BLOOD -
ORAL ADMINISTRATION OF PUTRESCINE INHIBITS CRYPTOSPORIDIUM PARVUM INFECTIONOF NEONATAL C57BL-6 MICE AND IS INDEPENDENT OF NITRIC OXIDE (NO) SYNTHESIS -
BOVINE CALCIUM-SENSING RECEPTOR GENE RESIDES ON CATTLE CHROMOSOME 1 -
VITAMIN D RECEPTOR HOMODIMER INTERACTIONS WITH THE MURINE OSTEOPONTIN RESPONSE ELEMENT -
NUCLEOTIDE SEQUENCE OF THE BOVINE VITMAIN D3 RECEPTOR -
RETINOIC ACID-INDUCED MODULATION OF INTERFERON-GAMMA (IFN-GAMMA) BY MITOGEN-STIMULATED PERIPHERAL BOVINE MONONUCLEAR LEUKOCYTES (PBML) -
1,25-DIHYDROXYVITAMIN D3 ENHANCES MILK ANTIBODY TITERS IN COWS VACCINATED WITH A J-5 VACCINE. -
CLONING AND SEQUENCING OF BOVINE INTERCELLULAR ADHESION MOLECULE (ICAM)-3 -
ORAL ADMINISTRATION OF PUTRESCINE REDUCES CRYPTOSPORIDIUM PARVUM OOCYST SHEDDING IN C57BL-6 AND TCR-DELTA-DEFICIENT MICE -
1,25-DIHYDROXYVITAMIN D3 INHIBITS SECRETION OF INTERFERON-GAMMA BY MITOGEN- AND ANTIGEN-STIMULATED BOVINE MONONUCLEAR LEUKOCYTES -
PREGNANCY AND LACTATION INCREASE VITAMIN D-DEPENDENT INTESTINAL MEMBRANE CALCIUM ATPASE AND CALCIUM BINDING PROTEIN MRNA EXPRESSION -
9,13-DI-CIS-RETINOIC ACID IS THE MAJOR CIRCULATING GEOMETRIC ISOMER OF RETINOIC ACID IN THE PERIPARTURIENT PERIOD -
IN VIVO PARATHYROID HORMONE STIMULATES IN VITRO BONE RESORPTION BY BOVINE MONOCYTES -
MILK FEVER AND DIETARY CATION-ANION BALANCE EFFECTS ON TISSUE VITAMIN D RECEPTOR CONCENTRATION IN PERIPARTURIENT DAIRY COWS -
THE ROLE OF DIETARY CALCIUM IN THE PHYSIOLOGY OF VITAMIN D TOXICITY: EXCESSDIETARY VITAMIN D3 BLUNTS PARATHYROID HORMONE INDUCTION OF KIDNEY 1-HYDROXYLASE -
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