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ARS Home » Pacific West Area » Pullman, Washington » Animal Disease Research » People & Locations » Margaret Highland (Maggie)

Margaret A Highland (Maggie)
Animal Disease Research
Veterinary Medical Officer

Phone: (509) 335-6327
Fax: (509) 335-8328
Room 3033

3033 ADBF, WASHINGTON STATE UNIV
PULLMAN , WA 991646630
Projects
Emerging Diseases, Q-fever: Genetics of Host Response and Transmission Risk for Coxiella burnetii
Cooperative Agreement (A)
  Accession Number: 429490
Identification of Host Factors and Immunopathogenesis of Pneumonia in Domestic and Bighorn Sheep
In-House Appropriated (D)
  Accession Number: 431731
Grand Mesa, Uncompahgre and Gunnison National Forests Plan Revision - U.S. Agricultural Research Service Cooperating Agency Agreement
Non-Funded Cooperative Agreement (N)
  Accession Number: 435542

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Mycoplasma ovipneumoniae associated with polymicrobial pneumonia in a free-ranging yearling caribou (Rangifer tarandus tarandus) from Alaska, USA -
Rovani, E.R., Beckman, K.B., Highland, M.A. 2019. Mycoplasma ovipneumoniae associated with polymicrobial pneumonia in a free-ranging yearling caribou (Rangifer tarandus tarandus) from Alaska, USA. Journal of Wildlife Diseases. https://www.jwildlifedis.org/doi/pdfplus/10.7589/2018-08-188.
Chapter 61: Caprine arthritis-encephalitis -
Murphy, B., Knowles, D.P., Highland, M.A. 2018. Chapter 61: Caprine arthritis-encephalitis. Book Chapter. https://www.anipedia.org/resources/caprine-arthritis-encephalitis/1027.
Chapter 60: Visna-maedi -
Murphy, B., Knowles, D., Highland, M.A. 2018. Chapter 60: Visna-maedi. Coetzer JAW, Oberem P., Thomson G.R., Maclachlan, N.J., Penrith, M.L., editors. Infectious Diseases of Livestock. Pretoria, South Africa: Anapedia. Available https://www.anipedia.org/resources/visna-maedi/1035.
Low-volume goat milk transmission of classical scrapie to lambs and goat kids -
Madsen-Bouterse, S.A., Highland, M.A., Dassanayake, R.P., Zhuang, D., Schneider, D.A. 2018. Low-volume goat milk transmission of classical scrapie to lambs and goat kids. PLoS One. https://doi.org/10.1371/journal.pone.0204281.
Identification of Mycoplasma ovipneumoniae in wildlife species beyond the subfamily caprinae -
Highland, M.A., Herndon, D.R., Bender, S., Hansen, L., Gerlach, R.F., Beckman, K.B. 2018. Identification of Mycoplasma ovipneumoniae in wildlife species beyond the subfamily caprinae. Emerging Infectious Diseases. https://wwwnc.cdc.gov/eid/article/24/12/18-0632_article.
Complete mitochondrial genome sequence of bighorn sheep -
Davenport, K.M., Duan, M., Hunter, S.S., New, D.D., Fagnan, M.W., Highland, M.A., Murdoch, B.M. 2018. Complete mitochondrial genome sequence of bighorn sheep. Genome Announcements. https://doi.org/10.1128/genomeA.00464-18.
A small intergenic region of lp17 is required for evasion of adaptive immunity and induction of disease pathology by the Lyme disease spirochete -
Casselli, T., Crowley, M.A., Highland, M.A., Tourand, Y., Bankhead, T. 2019. A small intergenic region of lp17 is required for evasion of adaptive immunity and induction of disease pathology by the Lyme disease spirochete. Cellular Microbiology. https://doi.org/10.1111/cmi.13029.
Passive transfer in domestic and bighorn lambs Total IgG in ewe sera and colostrum and serum IgG kinetics in lambs following colostrum ingestion are similar in domestic sheep and bighorn sheep (ovis aries and ovis canadensis) -
Highland, M.A., Berglund, A.K., Knowles, D.P. 2018. Total IgG concentrations in ewe sera and colostrum and kinetics in lambs following colostrum ingestion is similar in domestic sheep and bighorn sheep (ovis aries and ovis canadensis). Sheep and Goat Research Journal. 32:36-42.
High copy number of ovine gammaherpesvirus 2 DNA associated with malignant catarrhal fever-like syndrome in a lamb -
Phillips, I.L., Cunha, C.W., Galbraith, D., Highland, M.A., Bildfell, R.J., Li, H. 2018. High copy number of ovine gammaherpesvirus 2 DNA associated with malignant catarrhal fever-like syndrome in a lamb. Journal of Veterinary Diagnostic Investigation. https://doi.org/10.1177/1040638718766976.
Domestic sheep show average coxiella burnetii seropositivity generations after a sheep-associated human Q fever outbreak and lack detectable shedding by placental, vaginal, and fecal routes -
Oliveira, R.D., Mousel, M.R., Pabilonia, K.L., Highland, M.A., Taylor, J.B., Knowles, D.P., White, S.N. 2017. Domestic sheep show average coxiella burnetii seropositivity generations after a sheep-associated human Q fever outbreak and lack detectable shedding by placental, vaginal, and fecal routes. PLoS One. 12(11):30188054. https://doi.org/10.1371/journal.pone.0188054.
Underdominant KCC3b R31I association with blood sodium concentration in domestic sheep suggests role in oligomer function -
White, S.N., Oliveira, R.D., Mousel, M.R., Gonzalez, M.V., Highland, M.A., Herndon, M.K., Taylor, J.B., Knowles, D.P. 2017. Underdominant KCC3b R31I association with blood sodium concentration in domestic sheep suggests role in oligomer function. Animal Genetics. 48(5):626-627.
Small ruminant lentiviruses: Strain variation, viral tropism, and host genetics influence pathogenesis -
Highland, M.A. 2017. Small ruminant lentiviruses: Strain variation, viral tropism, and host genetics influence pathogenesis. Veterinary Pathology. 54(3):353-354.
Differences in leukocyte differentiation molecule abundances on domestic sheep (Ovis aries) and bighorn sheep (Ovis canadensis) neutrophils identified by flow cytometry -
Highland, M.A., Schneider, D.A., White, S.N., Madsen-Bouterse, S.A., Knowles Jr, D.P., Davis, W.C. 2016. Differences in leukocyte differentiation molecule abundances on domestic sheep (Ovis aries) and bighorn sheep (Ovis canadensis) neutrophils identified by flow cytometry . Comparative Immunology Microbiology and Infectious Diseases. doi: 10.1016/j.cimid.2016.04.006.
Differences in leukocyte differentiation molecule abundances on domestic sheep (Ovis aries) and bighorn sheep (Ovis canadensis) neutrophils identified by flow cytometry -
Highland, M.A., Schneider, D.A., White, S.N., Madsen-Bouterse, S.A., Knowles Jr, D.P., Davis, W.C. 2016. Differences in leukocyte differentiation molecule abundances on domestic sheep (Ovis aries) and bighorn sheep (Ovis canadensis) neutrophils identified by flow cytometry . Comparative Immunology Microbiology and Infectious Diseases. DOI: 10.1016/j.cimid.2016.04.006.
The sheep genome illuminates biology of the rumen and lipid metabolism -
Jiang, Y., Xie, M., Chen, W., Talbot, R., Maddox, J.F., Faraut, T., Wu, C., Muzny, D.M., Li, Y., Zhang, W., Stanton, J., Brauning, R., Barris, W.C., Hourlier, T., Aken, B., Searle, S.M., Adelson, D.L., Bian, C., Cam, G.R., Chen, Y., Chen, S., Desilva, U., Dixen, K., Dong, Y., Fan, G., Franklin, I.R., Fu, S., Fuentes-Utrilla, P., Guan, R., Highland, M.A., Holder, M., Huang, G., Ingham, A.B., Jhangiani, S.N., Kalra, D., Kovar, C.L., Lee, S.L., Liu, W., Liu, X., Lu, C., Lv, T., Mathew, T., Mcwilliam, S., Menzies, M., Pan, S., Robelin, D., Servin, B., Townley, D., Wang, W., Wei, B., White, S.N., Yang, X., Ye, C., Yue, Y., Zeng, P., Zhou, Q., Hansen, J.B., Kristensen, K., Gibbs, R., Flicek, P., Warkup, C.C., Jones, H.E., Oddy, H., Nicholas, F.W., Mcewan, J.C., Kijas, J., Wang, J., Worley, K., Archibald, A.L., Cockett, N., Xun, X., Wang, W., Dalrymple, B.P. 2014. The sheep genome illuminates biology of the rumen and lipid metabolism. Science. 344(6188):1168-1173.
Mutations in Ovis aries TMEM154 are associated with lower small ruminant lentivirus proviral concentration in one sheep flock -
Alshanbari, F.A., Mousel, M.R., Reynolds, J.O., Herrmann-Hoesing, L.M., Highland, M.A., Lewis, G.S., White, S.N. 2014. Mutations in Ovis aries TMEM154 are associated with lower small ruminant lentivirus proviral concentration in one sheep flock. Animal Genetics. 45(4):565-571.
Association analysis of variant near ZNF389 with ewe cumulative production in three sheep breeds -
White, S.N., Mousel, M.R., Gonzalez, M.V., Highland, M.A., Herrmann-Hoesing, L.M., Taylor, J.B., Knowles Jr, D.P. 2014. Association analysis of variant near ZNF389 with ewe cumulative production in three sheep breeds. Animal Genetics. 5(4):613-614.
Bighorn sheep pneumonia: Sorting out the cause of a polymicrobial disease -
Besser, T.E., Cassirer, F.E., Highland, M.A., Wollf, P., Justice-Allen, A., Mansfield, K., Davis, M.A., Foreyt, W. 2013. Bighorn sheep pneumonia: Sorting out the cause of a polymicrobial disease. Preventive Veterinary Medicine. 108(2-3):85-93.
Experimental induction of malignant catarrhal fever in pigs with ovine herpesvirus 2 by intranasal nebulization -
Li, H., Brooking, A., Cunha, C.W., Highland, M.A., O'Toole, D., Knowles Jr, D.P., Taus, N.S. 2012. Experimental induction of malignant catarrhal fever in pigs with ovine herpesvirus 2 by intranasal nebulization. Veterinary Microbiology. 159(3-4):485-489. doi:10.1016/j.vetmic.2012.04.016.
Causes of pneumonia epizootics among bighorn sheep, western United States, 2008-2010 Reprint Icon -
Besser, T.E., Highland, M.A., Baker, K., Cassirer, F.E., Anderson, N.J., Ramsey, J.M., Mansfield, K., Bruning, D.L., Wolff, P., Smith, J.B., Jenks, J.A. 2012. Causes of pneumonia epizootics among bighorn sheep, western United States, 2008-2010. Emerging Infectious Diseases. 18(3):406-14.