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ARS Home » Northeast Area » Beltsville, Maryland (BARC) » Beltsville Agricultural Research Center » Animal Biosciences & Biotechnology Laboratory » People & Locations » Mathias Schmelcher

Mathias Schmelcher (PhD)
Animal Biosciences & Biotechnology Laboratory
Research Molecular Biologist

Phone: (301) 504-5687
Fax: (301) 504-8571
Room 116

10300 BALTIMORE AVENUE
BLDG 230 BARC-EAST
BELTSVILLE, MD 20705

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Triple-acting lytic enzyme treatment of drug-resistant and intracellular Staphylococcus aureus - (Peer Reviewed Journal)
Becker, S.C., Roach, D.R., Chauhan, V., Shen, Y., Foster Frey, J.A., Powell, A.M., Buchannan, G., Lease, R., Mohammadi, H., Harty, W.J., Simmons, C.B., Schmelcher, M., Camp, M.J., Shields, K., Dowd, M., Dong, S., Baker, J.R., Sheen, T.R., Doran, K.S., Pritchard, D.G., Almeida, R., Nelson, D.C., Marriott, I., Lee, J.C., Donovan, D.M. 2016. Triple-acting lytic enzyme treatment of drug-resistant and intracellular Staphylococcus aureus. Scientific Reports. 6:25063.
The streptococcal phage SA2 and B30 endolysins act synergistically and kill mastitis causing streptococci in milk - (Peer Reviewed Journal)
Schmelcher, M., Pohl, C.S., Donovan, D.M. 2015. The streptococcal phage SA2 and B30 endolysins act synergistically and kill mastitis causing streptococci in milk. Applied and Environmental Microbiology. 99(20):8475-86.
Staphylococcus haemolyticus prophage endolysin relies on CHAP endopeptidase lytic activity for lysis from without - (Peer Reviewed Journal)
Schmelcher, M., Korobova, O., Schischkova, N., Kiseleva, N., Kopylov, P., Pryamchuk, S., Donovan, D.M., Abaev, I. 2012. Staphylococcus haemolyticus prophage endolysin relies on CHAP endopeptidase lytic activity for lysis from without. FEMS Microbiology Letters. 162(2-3):289-298.
Staphylococcal phage 2638a endolysin is lytic for Staphylococcus aureus and harbors an inter-lytic-domain cryptic translational start site. - (Peer Reviewed Journal)
Abaev, I., Foster Frey, J.A., Korobova, O., Shishkova, N., Kopylov, P., Pyramchuk, S., Schmelcher, M., Becker, S.C., Donovan, D.M. 2013. Staphylococcal phage 2638a endolysin is lytic for Staphylococcus aureus and harbors an inter-lytic-domain cryptic translational start site. Applied and Environmental Microbiology. 97(8):3449-3456.
Chimeric phage lysins act synergistically with lysostaphin to kill mastitis causing staphylococcus aureus in murine mammary glands - (Peer Reviewed Journal)
Schmelcher, M., Powell, A.M., Becker, S.C., Camp, M.J., Donovan, D.M. 2012. Chimeric phage lysins act synergistically with lysostaphin to kill mastitis causing staphylococcus aureus in murine mammary glands. Applied and Environmental Microbiology. 78(7):2297-305.
Endolysins as antimicrobials ()
Nelson, D.C., Schmelcher, M., Rodirguez, L., Klumpp, J., Pritchard, D.G., Dong, S., Donovan, D.M. 2012. Endolysins as antimicrobials. Advances in Virus Research.
Peptidoglycan Hydrolases for Control of Mastitis Pathogens - (Abstract Only)
Schmelcher, M., Becker, S.C., Foster Frey, J.A., Donovan, D.M. 2009. Peptidoglycan Hydrolases for Control of Mastitis Pathogens. Evergreen International Phage Meeting.
Engineering Antimicrobials Refractory to Resistance - (Abstract Only)
Becker, S.C., Pohl, C.S., Mohammadi, H., Schmelcher, M., Foster Frey, J.A., Lease, R.A., Don, S., Baker, J.R., Pritchard, D.G., Donovan, D.M. 2009. Engineering Antimicrobials Refractory to Resistance. Evergreen International Phage Meeting.
ENGINEERING OF PEPTIDOGLYCAN HYDROLASES FOR CONTROL OF PATHOGENIC BACTERIA - (Abstract Only)
Schmelcher, M., Loessner, M.J., Donovan, D.M. 2009. ENGINEERING OF PEPTIDOGLYCAN HYDROLASES FOR CONTROL OF PATHOGENIC BACTERIA. BARC Poster Day.