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ARS Home » Southeast Area » New Orleans, Louisiana » Southern Regional Research Center » Food and Feed Safety Research » People & Locations » Brian Mack

Brian Michael Mack
Food and Feed Safety Research
Biological Science Technician

Phone: (504) 286-4378
Fax:
Room 2117

1100 ROBERT E. LEE BLVD
BLDG 001 SRRC
NEW ORLEANS , LA 70124

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Draft genome sequence of Erysiphe pulchra, a dogwood powdery mildew pathogen -
A metagenomics study of the corn kernel and silk microbiome following infection with aflatoxigenic and non-aflatoxigenic Aspergillus flavus strains -
Environmental interactions that influence secondary metabolism and development in the saprophytic crop pathogen Aspergillus flavus -
Whole genome comparison of Aspergillus flavus L-morphotype strain NRRL 3357 (type) and S-morphotype strain AF70 -
Gilbert, M.K., Mack, B.M., Moore, G.G., Downey, D.L., Lebar, M.D., Joarder, V., Losada, L., Yu, J., Nierman, W.C., Bhatnagar, D. 2018. Whole genome comparison of Aspergillus flavus L-morphotype strain NRRL 3357 (type) and S-morphotype strain AF70. PLoS One. 13(7):e0199169. https://doi.org/10.1371/journal.pone.0199169.
Identification and functional analysis of the aspergillic acid gene cluster in Aspergillus flavus -
Lebar, M.D., Cary, J.W., Majumdar, R., Carter-Wientjes, C.H., Mack, B.M., Wei, Q., Uka, V., De Saeger, S., Diana Di Mavungu, J. 2018. Identification and functional analysis of the aspergillic acid gene cluster in Aspergillus flavus. Fungal Genetics and Biology. 116:14-23.
Aspergillus flavus GPI-anchored protein-encoding ecm33 has a role in growth, development, aflatoxin biosynthesis, and maize infection -
Chang, P.-K., Zhang, Q., Scharfenstein, L.L., Mack, B.M., Yoshimi, A., Miyazawa, K., Abe, K. 2018. Aspergillus flavus GPI-anchored protein-encoding ecm33 has a role in growth, development, aflatoxin biosynthesis, and maize infection. Applied Microbiology and Biotechnology. https://doi.org/10.1007/s00253-018-9012-7.
Genome sequence of an aflatoxigenic pathogen of Argentinian peanut, Aspergillus arachidicola -
Moore, G.G., Mack, B.M., Beltz, S.B., Puel, O. 2018. Genome sequence of an aflatoxigenic pathogen of Argentinian peanut, Aspergillus arachidicola. BMC Genomics. 19:189. https://doi.org/10.1186/s12864-018-4576-2.
The Aspergillus flavus spermidine synthase (spds) gene, is required for normal development, aflatoxin production, and pathogenesis during infection of maize kernels -
Majumdar, R., Lebar, M.D., Mack, B.M., Minocha, R., Minocha, S., Carter-Wientjes, C.H., Sickler, C.M., Rajasekaran, K., Cary, J.W. 2018. The Aspergillus flavus spermidine synthase (spds) gene, is required for normal development, aflatoxin production, and pathogenesis during infection of maize kernels. Frontiers in Plant Science. 9:317. https://doi.org/10.3389/fpls.2018.00317.
Carbon dioxide mediates the response to temperature and water activity levels in Aspergillus flavus during infection of maize kernels -
Gilbert, M.K., Medina, A., Mack, B.M., Lebar, M.D., Rodriguez, A., Bhatnagar, D., Magan, N., Obrian, G., Payne, G. 2018. Carbon dioxide mediates the response to temperature and water activity levels in Aspergillus flavus during infection of maize kernels. Toxins. 10(1):5. https://doi.org/10.3390/toxins10010005.
The Aspergillus flavus homeobox gene, hbx1, is required for development and aflatoxin production -
Cary, J.W., Harris-Coward, P.Y., Scharfenstein, L.L., Mack, B.M., Chang, P.-K., Wei, Q., Lebar, M.D., Carter-Wientjes, C.H., Majumdar, R., Mitra, C., Banerjee, S., Chanda, A. 2017. The Aspergillus flavus homeobox gene, hbx1, is required for development and aflatoxin production. Toxins. 9(10):315. https://doi.org/10.3390/toxins9100315.
Interactions between water activity and temperature on the Aspergillus flavus transcriptome and aflatoxin B1 production -
Medina, A., Gilbert, M.K., Mack, B.M., OBrian, G.R., Rodriguez, A., Bhatnagar, D., Payne, G., Magan, N. 2017. Interactions between water activity and temperature on the Aspergillus flavus transcriptome and aflatoxin B1 production. International Journal of Food Microbiology. 256:36-44.
Transcriptome of Aspergillus flavus aswA (AFLA_085170) deletion strain related to sclerotial development and production of secondary metabolites -
Chang, P.-K., Scharfenstein, L.L., Mack, B.M., Li, R.W. 2017. Transcriptome of Aspergillus flavus aswA (AFLA_085170) deletion strain related to sclerotial development and production of secondary metabolites. National Center for Biotechnology Information (NCBI). Accession: SRP082149.
Effect of water activity, temperature, and carbon dioxide on the Aspergillus flavus transcriptome and aflatoxin B1 production -
Gilbert, M.K., Medina-Vaya, A., Mack, B.M., Lebar, M.D., Rodriguez, A., Bhatnagar, D., Magan, N., Obrian, G., Payne, G. 2017. Effect of water activity, temperature, and carbon dioxide on the Aspergillus flavus transcriptome and aflatoxin B1 production. National Center for Biotechnology Information (NCBI). Accession: PRJNA380582.
Naturally occurring high oleic acid cottonseed oil: identification and functional analysis of a mutant allele of Gossypium barbadense fatty acid desaturase-2 -
Shockey, J., Dowd, M., Mack, B., Gilbert, M., Scheffler, B., Ballard, L., Frelichowski, J., Mason, C. 2017. Naturally occurring high oleic acid cottonseed oil: identification and functional analysis of a mutant allele of Gossypium barbadense fatty acid desaturase-2. Planta. 245:611-622.
Draft genome sequence of an aflatoxigenic Aspergillus species, A. bombycis -
Moore, G.G., Mack, B.M., Beltz, S.B., Gilbert, M.K. 2016. Draft genome sequence of an aflatoxigenic Aspergillus species, A. bombycis. Genome Biology and Evolution. 8(11):3297-3300. doi:10.1093/gbe/evw238.
Use of functional genomics to assess the climate change impact on Aspergillus flavus and aflatoxin production -
Gilbert, M.K., Mack, B.M., Payne, G.A., Bhatnagar, D. 2016. Use of functional genomics to assess the climate change impact on Aspergillus flavus and aflatoxin production. World Mycotoxin Journal. 9(5):665-672. doi:10.3920/WMJ2016.2049.
Draft genome sequences of two closely related aflatoxigenic Aspergillus species obtained from the Ivory Coast -
Moore, G.G., Mack, B.M., Beltz, S.B. 2015. Draft genome sequences of two closely related aflatoxigenic Aspergillus species obtained from the Ivory Coast. Genome Biology and Evolution. 8(3):729-732.
RNA sequencing of an nsdC mutant reveals global regulation of secondary metabolic gene clusters in Aspergillus flavus -
Gilbert, M.K., Mack, B.M., Wei, Q., Bland, J.M., Bhatnagar, D., Cary, J.W. 2016. RNA sequencing of an nsdC mutant reveals global regulation of secondary metabolic gene clusters in Aspergillus flavus. Microbiological Research. 182:150-161.
Transcriptome analysis of Aspergillus flavus reveals veA-dependent regulation of secondary metabolite gene clusters, including the novel aflavarin cluster -
Cary, J.W., Han, Z., Yin, Y., Lohmar, J.M., Shantappa, S., Harris-Coward, P.Y., Mack, B.M., Ehrlich, K.C., Wei, Q., Arroyo-Manzanares, N., Uka, V., Vanhaecke, L., Bhatnagar, D., Yu, J., Nierman, W.C., Johns, M., Sorensen, D., Shen, H., De Saeger, S., Diana Di Mavungu, J., Calvo, A.M. 2015. Transcriptome analysis of Aspergillus flavus reveals veA-dependent regulation of secondary metabolite gene clusters, including the novel aflavarin cluster. Eukaryotic Cell. 14(10):983-997. doi: 10.1128/EC.00092-15.
Genomic sequence of the aflatoxigenic filamentous fungus Aspergillus nomius -
Moore, G.G., Mack, B.M., Beltz, S.B. 2015. Genomic sequence of the aflatoxigenic filamentous fungus Aspergillus nomius. BMC Genomics. 16:551. doi:10.1186/s12864-015-1719-6.
Analysis of an nsdC mutant in Aspergillus flavus reveals an extensive role in the regulation of several secondary metabolic gene clusters -
Comparison of expression of secondary metabolite biosynthesis cluster genes in Aspergillus flavus, A. parasiticus, and A. oryzae -
Ehrlich, K., Mack, B.M. 2014. Comparison of expression of secondary metabolite biosynthesis cluster genes in Aspergillus flavus, A. parasiticus, and A. oryzae. Toxins. 6:1916-1928.
RNA-seq analysis of an nsdC mutant in Aspergillus flavus -
Genomic sequence for the aflatoxigenic filamentous fungus Aspergillus nomius -
Transcriptomic profiles of Aspergillus flavus CA42, a strain that produces small sclerotia, by decanal treatment and after recovery -
Chang, P.-K., Scharfenstein, L.L., Mack, B.M., Yu, J., Ehrlich, K. 2014. Transcriptomic profiles of Aspergillus flavus CA42, a strain that produces small sclerotia, by decanal treatment and after recovery. Fungal Genetics and Biology. 68:39-47.
Transcriptomic profiling of decanal effects on Aspergillus flavus gene expression in development and secondary metabolism -
Chang, P-K., Scharfenstein, L.L., Yu, J., Mack, B.M., Ehrlich, K.C., Losada, L., Nierman, W.C., Bhatnagar, D. 2014. Transcriptomic profiling of decanal effects on Aspergillus flavus gene expression in development and secondary metabolism. National Center for Biotechnology Information (NCBI). Accession: SRX471362.
Testing the efficacy of eGFP-transformed Aspergillus flavus as biocontrol strains -
Moore, G.G., Mack, B.M., Beltz, S.B. 2013. Testing the efficacy of eGFP-transformed Aspergillus flavus as biocontrol strains. Food and Nutrition Sciences. 4:469-479. doi:10.4236/fns.2013.44060.
Association with AflR in endosomes reveals new functions for AflJ in aflatoxin biosynthesis -
Ehrlich, K., Mack, B.M., Wei, Q., Li, P., Roze, L.V., Dazzo, F., Cary, J.W., Bhatnagar, D., Linz, J.E. 2012. Association with AflR in endosomes reveals new functions for AflJ in aflatoxin biosynthesis. Toxins. 4:1582-1600.
Deletion of the Aspergillus flavus orthologue of A. nidulans fluG reduces conidiation and promotes production of sclerotia but does not abolish aflatoxin biosynthesis -
Chang, P-K., Scharfenstein, L.L., Mack, B.M., Ehrlich, K. 2012. Deletion of the Aspergillus flavus orthologue of A. nidulans fluG reduces conidiation and promotes production of sclerotia but does not abolish aflatoxin biosynthesis. Applied and Environmental Microbiology. 78(21):7557-7563.
NsdC and NsdD affect Aspergillus flavus morphogenesis and aflatoxin production -
Cary, J.W., Harris-Coward, P.Y., Ehrlich, K., Mack, B.M., Kale, S.P., Larey, C., Calvo, A.M. 2012. NsdC and NsdD affect Aspergillus flavus morphogenesis and aflatoxin production. Eukaryotic Cell. 11(9):1104-1111.