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ARS Home » Southeast Area » New Orleans, Louisiana » Southern Regional Research Center » Food and Feed Safety Research » People & Locations » Brian Mack

Brian Michael Mack
Food and Feed Safety Research
Biological Science Technician

Phone: (504) 286-4378
Fax:
Room 2117

1100 ROBERT E. LEE BLVD
BLDG 001 SRRC
NEW ORLEANS , LA 70124

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Environmental interactions that influence secondary metabolism and development in the saprophytic crop pathogen Aspergillus flavus -
Whole genome comparison of Aspergillus flavus L-morphotype strain NRRL 3357 (type) and S-morphotype strain AF70 -
Identification and functional analysis of the aspergillic acid gene cluster in Aspergillus flavus -
Lebar, M.D., Cary, J.W., Majumdar, R., Carter-Wientjes, C.H., Mack, B.M., Wei, Q., Uka, V., De Saeger, S., Diana Di Mavungu, J. 2018. Identification and functional analysis of the aspergillic acid gene cluster in Aspergillus flavus. Fungal Genetics and Biology. 116:14-23.
Aspergillus flavus GPI-anchored protein-encoding ecm33 has a role in growth, development, aflatoxin biosynthesis, and maize infection -
Chang, P.-K., Zhang, Q., Scharfenstein, L.L., Mack, B.M., Yoshimi, A., Miyazawa, K., Abe, K. 2018. Aspergillus flavus GPI-anchored protein-encoding ecm33 has a role in growth, development, aflatoxin biosynthesis, and maize infection. Applied Microbiology and Biotechnology. https://doi.org/10.1007/s00253-018-9012-7.
Genome sequence of an aflatoxigenic pathogen of Argentinian peanut, Aspergillus arachidicola -
Moore, G.G., Mack, B.M., Beltz, S.B., Puel, O. 2018. Genome sequence of an aflatoxigenic pathogen of Argentinian peanut, Aspergillus arachidicola. BMC Genomics. 19:189. https://doi.org/10.1186/s12864-018-4576-2.
The Aspergillus flavus spermidine synthase (spds) gene, is required for normal development, aflatoxin production, and pathogenesis during infection of maize kernels -
Majumdar, R., Lebar, M.D., Mack, B.M., Minocha, R., Minocha, S., Carter-Wientjes, C.H., Sickler, C.M., Rajasekaran, K., Cary, J.W. 2018. The Aspergillus flavus spermidine synthase (spds) gene, is required for normal development, aflatoxin production, and pathogenesis during infection of maize kernels. Frontiers in Plant Science. 9:317. https://doi.org/10.3389/fpls.2018.00317.
Carbon dioxide mediates the response to temperature and water activity levels in Aspergillus flavus during infection of maize kernels -
Gilbert, M.K., Medina, A., Mack, B.M., Lebar, M.D., Rodriguez, A., Bhatnagar, D., Magan, N., Obrian, G., Payne, G. 2018. Carbon dioxide mediates the response to temperature and water activity levels in Aspergillus flavus during infection of maize kernels. Toxins. 10(1):5. doi:10.3390/toxins10010005.
The Aspergillus flavus homeobox gene, hbx1, is required for development and aflatoxin production -
Cary, J.W., Harris-Coward, P.Y., Scharfenstein, L.L., Mack, B.M., Chang, P.-K., Wei, Q., Lebar, M.D., Carter-Wientjes, C.H., Majumdar, R., Mitra, C., Banerjee, S., Chanda, A. 2017. The Aspergillus flavus homeobox gene, hbx1, is required for development and aflatoxin production. Toxins. 9(10):315. doi:10.3390/toxins9100315.
Interactions between water activity and temperature on the Aspergillus flavus transcriptome and aflatoxin B1 production -
Medina, A., Gilbert, M.K., Mack, B.M., OBrian, G.R., Rodriguez, A., Bhatnagar, D., Payne, G., Magan, N. 2017. Interactions between water activity and temperature on the Aspergillus flavus transcriptome and aflatoxin B1 production. International Journal of Food Microbiology. 256:36-44.
Transcriptome of Aspergillus flavus aswA (AFLA_085170) deletion strain related to sclerotial development and production of secondary metabolites -
Chang, P.-K., Scharfenstein, L.L., Mack, B.M., Li, R.W. 2017. Transcriptome of Aspergillus flavus aswA (AFLA_085170) deletion strain related to sclerotial development and production of secondary metabolites. National Center for Biotechnology Information (NCBI). Accession: SRP082149.
Effect of water activity, temperature, and carbon dioxide on the Aspergillus flavus transcriptome and aflatoxin B1 production -
Gilbert, M.K., Medina-Vaya, A., Mack, B.M., Lebar, M.D., Rodriguez, A., Bhatnagar, D., Magan, N., Obrian, G., Payne, G. 2017. Effect of water activity, temperature, and carbon dioxide on the Aspergillus flavus transcriptome and aflatoxin B1 production. National Center for Biotechnology Information (NCBI). Accession: PRJNA380582.
Naturally occurring high oleic acid cottonseed oil: identification and functional analysis of a mutant allele of Gossypium barbadense fatty acid desaturase-2 -
Shockey, J., Dowd, M., Mack, B., Gilbert, M., Scheffler, B., Ballard, L., Frelichowski, J., Mason, C. 2017. Naturally occurring high oleic acid cottonseed oil: identification and functional analysis of a mutant allele of Gossypium barbadense fatty acid desaturase-2. Planta. 245:611-622.
Draft genome sequence of an aflatoxigenic Aspergillus species, A. bombycis -
Moore, G.G., Mack, B.M., Beltz, S.B., Gilbert, M.K. 2016. Draft genome sequence of an aflatoxigenic Aspergillus species, A. bombycis. Genome Biology and Evolution. 8(11):3297-3300. doi:10.1093/gbe/evw238.
Use of functional genomics to assess the climate change impact on Aspergillus flavus and aflatoxin production -
Gilbert, M.K., Mack, B.M., Payne, G.A., Bhatnagar, D. 2016. Use of functional genomics to assess the climate change impact on Aspergillus flavus and aflatoxin production. World Mycotoxin Journal. 9(5):665-672. doi:10.3920/WMJ2016.2049.
Draft genome sequences of two closely related aflatoxigenic Aspergillus species obtained from the Ivory Coast -
Moore, G.G., Mack, B.M., Beltz, S.B. 2015. Draft genome sequences of two closely related aflatoxigenic Aspergillus species obtained from the Ivory Coast. Genome Biology and Evolution. 8(3):729-732.
RNA sequencing of an nsdC mutant reveals global regulation of secondary metabolic gene clusters in Aspergillus flavus -
Gilbert, M.K., Mack, B.M., Wei, Q., Bland, J.M., Bhatnagar, D., Cary, J.W. 2016. RNA sequencing of an nsdC mutant reveals global regulation of secondary metabolic gene clusters in Aspergillus flavus. Microbiological Research. 182:150-161.
Transcriptome analysis of Aspergillus flavus reveals veA-dependent regulation of secondary metabolite gene clusters, including the novel aflavarin cluster -
Cary, J.W., Han, Z., Yin, Y., Lohmar, J.M., Shantappa, S., Harris-Coward, P.Y., Mack, B.M., Ehrlich, K.C., Wei, Q., Arroyo-Manzanares, N., Uka, V., Vanhaecke, L., Bhatnagar, D., Yu, J., Nierman, W.C., Johns, M., Sorensen, D., Shen, H., De Saeger, S., Diana Di Mavungu, J., Calvo, A.M. 2015. Transcriptome analysis of Aspergillus flavus reveals veA-dependent regulation of secondary metabolite gene clusters, including the novel aflavarin cluster. Eukaryotic Cell. 14(10):983-997. doi: 10.1128/EC.00092-15.
Genomic sequence of the aflatoxigenic filamentous fungus Aspergillus nomius -
Moore, G.G., Mack, B.M., Beltz, S.B. 2015. Genomic sequence of the aflatoxigenic filamentous fungus Aspergillus nomius. BMC Genomics. 16:551. doi:10.1186/s12864-015-1719-6.
Analysis of an nsdC mutant in Aspergillus flavus reveals an extensive role in the regulation of several secondary metabolic gene clusters -
Comparison of expression of secondary metabolite biosynthesis cluster genes in Aspergillus flavus, A. parasiticus, and A. oryzae -
Ehrlich, K., Mack, B.M. 2014. Comparison of expression of secondary metabolite biosynthesis cluster genes in Aspergillus flavus, A. parasiticus, and A. oryzae. Toxins. 6:1916-1928.
RNA-seq analysis of an nsdC mutant in Aspergillus flavus -
Genomic sequence for the aflatoxigenic filamentous fungus Aspergillus nomius -
Transcriptomic profiles of Aspergillus flavus CA42, a strain that produces small sclerotia, by decanal treatment and after recovery -
Chang, P.-K., Scharfenstein, L.L., Mack, B.M., Yu, J., Ehrlich, K. 2014. Transcriptomic profiles of Aspergillus flavus CA42, a strain that produces small sclerotia, by decanal treatment and after recovery. Fungal Genetics and Biology. 68:39-47.
Transcriptomic profiling of decanal effects on Aspergillus flavus gene expression in development and secondary metabolism -
Chang, P-K., Scharfenstein, L.L., Yu, J., Mack, B.M., Ehrlich, K.C., Losada, L., Nierman, W.C., Bhatnagar, D. 2014. Transcriptomic profiling of decanal effects on Aspergillus flavus gene expression in development and secondary metabolism. National Center for Biotechnology Information (NCBI). Accession: SRX471362.
Testing the efficacy of eGFP-transformed Aspergillus flavus as biocontrol strains -
Moore, G.G., Mack, B.M., Beltz, S.B. 2013. Testing the efficacy of eGFP-transformed Aspergillus flavus as biocontrol strains. Food and Nutrition Sciences. 4:469-479. doi:10.4236/fns.2013.44060.
Association with AflR in endosomes reveals new functions for AflJ in aflatoxin biosynthesis -
Ehrlich, K., Mack, B.M., Wei, Q., Li, P., Roze, L.V., Dazzo, F., Cary, J.W., Bhatnagar, D., Linz, J.E. 2012. Association with AflR in endosomes reveals new functions for AflJ in aflatoxin biosynthesis. Toxins. 4:1582-1600.
Deletion of the Aspergillus flavus orthologue of A. nidulans fluG reduces conidiation and promotes production of sclerotia but does not abolish aflatoxin biosynthesis -
Chang, P-K., Scharfenstein, L.L., Mack, B.M., Ehrlich, K. 2012. Deletion of the Aspergillus flavus orthologue of A. nidulans fluG reduces conidiation and promotes production of sclerotia but does not abolish aflatoxin biosynthesis. Applied and Environmental Microbiology. 78(21):7557-7563.
NsdC and NsdD affect Aspergillus flavus morphogenesis and aflatoxin production -
Cary, J.W., Harris-Coward, P.Y., Ehrlich, K., Mack, B.M., Kale, S.P., Larey, C., Calvo, A.M. 2012. NsdC and NsdD affect Aspergillus flavus morphogenesis and aflatoxin production. Eukaryotic Cell. 11(9):1104-1111.