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ARS Home » Pacific West Area » Pullman, Washington » Animal Disease Research » People & Locations » W Carl Johnson (Carl)
W Carl Johnson (Carl)
Animal Disease Research
Microbiologist

Phone: (509) 335-3512
Fax: (509) 335-8328

308 BUSTAD HALL, WSU
PULLMAN, WA 991646630

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Differential expression of calcium-dependent protein kinase 4, tubulin tyrosine ligase, and methyltransferase by xanthurenic acid-induced Babesia bovis sexual stages Reprint Icon - (Peer Reviewed Journal)
Hussein, H.E., Johnson, W.C., Taus, N.S., Capelli-Peixoto, J., Suarez, C.E., Mousel, M.R., Ueti, M.W. 2021. Differential expression of calcium-dependent protein kinase 4, tubulin tyrosine ligase, and methyltransferase by xanthurenic acid-induced Babesia bovis sexual stages. Parasites & Vectors. 14:395. https://doi.org/10.1186/s13071-021-04902-3.
Molecular and serological detection of piroplasms in horses from Nigerian Reprint Icon - (Peer Reviewed Journal)
Idoko, I.S., Edah, R.E., Adamu, A.M., Machunga-Mambula, S., Okubanjo, O.O., Balogun, E.O., Adamu, S., Johnson, W.C., Kappmeyer, L.S., Mousel, M.R., Ueti, M.W. 2021. Molecular and serological detection of piroplasms in horses from Nigerian. Pathogens. 10(5). Article 508. https://doi.org/10.3390/pathogens10050508.
Transcriptome dataset of Babesia bovis life stages within vertebrate and invertebrate hosts Reprint Icon - (Peer Reviewed Journal)
Ueti, M.W., Johnson, W.C., Kappmeyer, L.S., Herndon, D.R., Mousel, M.R., Reif, K.E., Taus, N.S., Ifeonu, O.O., Silva, J.C., Suarez, C.E., Brayton, K.A. 2020. Transcriptome dataset of Babesia bovis life stages within vertebrate and invertebrate hosts. Data in Brief. 33. Article 106533. https://doi.org/10.1016/j.dib.2020.106533.
Comparative analysis of gene expression between Babesia bovis blood stages and kinetes allowed by improved genome annotation. Reprint Icon - (Peer Reviewed Journal)
Ueti, M.W., Johnson, W.C., Kappmeyer, L.S., Herndon, D.R., Mousel, M.R., Reif, K.E., Taus, N.S., Ifeonu, O.O., Silva, J.C., Suarez, C.E., Brayton, K.A. 2020. Comparative analysis of gene expression between Babesia bovis blood stages and kinetes allowed by improved genome annotation.. International Journal for Parasitology. 51(2-3):123-136. https://doi.org/10.1016/j.ijpara.2020.08.006.
Molecular detection of Theileria species and Babesia caballi from horses in Nigeria Reprint Icon - (Peer Reviewed Journal)
Philip, M.W., Kappmeyer, L.S., Johnson, W.C., Kudi, C.A., Oluyinka, O.O., Balogun, E.O., Richard, E.E., Onoja, E., Sears, K.P., Ueti, M.W. 2020. Molecular detection of Theileria species and Babesia caballi from horses in Nigeria. Parasitology Research. 119:2955-2963. https://doi.org/10.1007/s00436-020-06797-y.
Quantitative analysis of Anaplasma marginale acquisition and transmission by Dermacentor andersoni fed in vitro Reprint Icon - (Peer Reviewed Journal)
Vimonish, R., Johnson, W.C., Mousel, M.R., Brayton, K.A., Scoles, G.A., Noh, S.M., Ueti, M.W. 2020. Quantitative analysis of Anaplasma marginale acquisition and transmission by Dermacentor andersoni fed in vitro. Scientific Reports. 10:740. https://doi.org/10.1038/s41598-019-57390-y.
Identification of proteins expressed by Babesia bigemina kinetes Reprint Icon - (Peer Reviewed Journal)
Bohaliga, G.A.R., Johnson, W.C., Taus, N.S., Hussein, H.E., Bastos, R.G., Suarez, C.E., Scoles, G.A., Ueti, M.W. 2019. Identification of proteins expressed by Babesia bigemina kinetes. Parasites & Vectors. 12(1). https://doi.org/10.1186/s13071-019-3531-7.
Silencing expression of the Rhipicephalus microplus vitellogenin receptor gene blocks Babesia bovis transmission and interferes with oocyte maturation Reprint Icon - (Peer Reviewed Journal)
Hussein, H.E., Johnson, W.C., Taus, N.S., Suarez, C.E., Scoles, G.A., Ueti, M.W. 2019. Silencing expression of the Rhipicephalus microplus vitellogenin receptor gene blocks Babesia bovis transmission and interferes with oocyte maturation. Parasites & Vectors. https://doi.org/10.1186/s13071-018-3270-1.
Silencing expression of the Rhipicephalus microplus vitellogenin receptor gene blocks Babesia bovis transmission and interferes with oocyte maturation Reprint Icon - (Peer Reviewed Journal)
Hala, H.E., Johnson, W.C., Taus, N.S., Suarez, C.E., Scoles, G.A., Ueti, M.W. 2019. Silencing expression of the Rhipicephalus microplus vitellogenin receptor gene blocks Babesia bovis transmission and interferes with oocyte maturation. Parasites & Vectors. 12(1):7. https://doi.org/10.1186/s13071-018-3270-1.
Identification of a putative methyltransferase gene of Babesia bigemina as a novel molecular biomarker uniquely expressed in parasite tick stages. Reprint Icon - (Peer Reviewed Journal)
Bohaliga, G.A., Johnson, W.C., Taus, N.S., Hussein, H.E., Ueti, M.W. 2018. Identification of a putative methyltransferase gene of Babesia bigemina as a novel molecular biomarker uniquely expressed in parasite tick stages. Parasites & Vectors. 11(1):480. https://doi.org/10.1186/s13071-018-3052-9.
First report of Anaplasma marginale infection in goats, Brazil Reprint Icon - (Peer Reviewed Journal)
Dasilva, N.B., Ueti, M.W., Johnson, W.C., Mira, A., Schnittger, L., Valente, J.D., Vidotto, O., Masterson, H.E., Taus, N.S., Vieira, T.S. 2018. First report of Anaplasma marginale infection in goats, Brazil. PLOS Neglected Tropical Diseases. https://doi.org/10.1371/journal.pone.0202140.
First report of Anaplasma marginale infection in goats, Brazi Reprint Icon - (Peer Reviewed Journal)
Dasilva, N.B., Ueti, M.W., Johnson, W.C., Mira, A., Schnittger, L., Valente, J.D., Vidotto, O., Masterson, H.E., Taus, N.S., Vieira, T.S. 2018. First report of Anaplasma marginale infection in goats, Brazi. PLoS One. 13(8):e0202140. https://doi.org/10.1371/journal.pone.0202140.
Spherical body protein 2 truncated copy 11 as a specific babesia bovis attenuation marker Reprint Icon - (Peer Reviewed Journal)
Gallego-Lopez, G., Lau, A., Johnson, W.C., Ueti, M.W., Suarez, C.E. 2018. Spherical body protein 2 truncated copy 11 as a specific babesia bovis attenuation marker. Parasites & Vectors. 11:169. https://doi.org/10.1186/s13071-018-2782-z.
Molecular detection and characterization of theileria spp infecting cattle in Sennar State, Sudan Reprint Icon - (Peer Reviewed Journal)
Mohamad, S.B., Alagib, A., Abdelkareim, T.B., Haasan, M.M., Johnson, W.C., Hussein, H.E., Taus, N.S., Ueti, M.W. 2018. Molecular detection and characterization of theileria spp infecting cattle in Sennar State, Sudan. Parasitology Research. 117(4):1271-1276. https://doi.org/10.1007/s00436-018-5775-0.
The babesia bovis hap2 gene is not required for blood stage replication, but expressed upon in vitro sexual stage induction Reprint Icon - (Peer Reviewed Journal)
Hussein, H.E., Bastos, R.G., Schneider, D.A., Johnson, W.C., Adham, F.K., Davis, W.C., Laughery, J.M., Herndon, D.R., Alzan, H.F., Ueti, M.W., Suarez, C.E. 2017. The babesia bovis hap2 gene is not required for blood stage replication, but expressed upon in vitro sexual stage induction. PLOS Neglected Tropical Diseases. 11(10):e0005965. https://doi.org/10.1371/journal.pntd.0005965.
The transcription factor relish controls anaplasma marginale infection in the bovine tick rhipicephalus microplus - (Peer Reviewed Journal)
Capelli-Peixoto, J., Carvalho, D.D., Johnson, W.C., Scoles, G.A., Fogaça, A.C., Daffre, S., Ueti, M.W. 2017. The transcription factor relish controls anaplasma marginale infection in the bovine tick rhipicephalus microplus. Developmental and Comparative Immunology. doi: 10.1016/j.dci.2017.04.005.
Analysis of stage-specific protein expression during babesia bovis development within female rhipicephalus microplus - (Peer Reviewed Journal)
Johnson, W.C., Taus, N.S., Reif, K.E., Bohaliga, G., Kappmeyer, L.S., Ueti, M.W. 2017. Analysis of stage-specific protein expression during babesia bovis development within female rhipicephalus microplus. Journal of Proteome Research. 16(3):1327-1338.
A virulent babesia bovis strain failed to infect white-tailed deer (Odocoileus virginianus) Reprint Icon - (Peer Reviewed Journal)
Ueti, M.W., Olafson, P.U., Freeman, J.M., Johnson, W.C., Scoles, G.A. 2015. A virulent babesia bovis strain failed to infect white-tailed deer (Odocoileus virginianus). PLoS One. doi: 10.1371/journal.pone.0131018.
Ovine leukocyte profiles do not associate with variation in the prion gene, but are breed-dependent - (Peer Reviewed Journal)
Mousel, M.R., White, S.N., Herndon, D.R., Reynolds, J.O., Gonzalez, M., Johnson, W.C., Ueti, M.W., Taylor, J.B., Knowles Jr, D.P. 2015. Ovine leukocyte profiles do not associate with variation in the prion gene, but are breed-dependent. Animal Genetics. 47(1):136-37.
Loss of immunization-induced epitope-specific CD4 T-cell response following anaplasma marginale infection requires presence of the T-cell epitope on the pathogen and is not associated with an increase in lymphocytes - (Peer Reviewed Journal)
Brown, W.C., Turse, J.E., Lawrence, P.K., Johnson, W.C., Scoles, G.A., Deringer, J.R., Sutten, E.L., Han, S., Norimine, J. 2015. Loss of immunization-induced epitope-specific CD4 T-cell response following anaplasma marginale infection requires presence of the T-cell epitope on the pathogen and is not associated with an increase in lymphocytes. Clinical and Vaccine Immunology. 22(7):742-53.
Association of anaplasma marginale strain superinfection with infection prevalence within tropical regions - (Peer Reviewed Journal)
Castañeda-Ortiz, E.J., Ueti, M.W., Minerva, C., Mosqueda, J.J., Mousel, M.R., Johnson, W.C., Palmer, G.H. 2015. Association of anaplasma marginale strain superinfection with infection prevalence within tropical regions. PLoS One. doi: 10.1371/journal.pone.0120748.
Lymphocytes and macrophages are infected by theileria equi, but T cells and B cells are not required to establish infection in vivo - (Peer Reviewed Journal)
Ramsay, J.D., Ueti, M.W., Johnson, W.C., Scoles, G.A., Knowles Jr, D.P., Mealey, R.H. 2013. Lymphocytes and macrophages are infected by theileria equi, but T cells and B cells are not required to establish infection in vivo. PLoS One. DOI: 10.1371.
A divergent artiodactyl MYADM-like repeat is associated with erythrocyte traits and weight of lamb weaned in domestic sheep - (Peer Reviewed Journal)
Gonzalez, M.V., Mousel, M.R., Herndon, D.R., Jiang, Y., Dalrymple, B.P., Reynolds, J.O., Johnson, W.C., Herrmann-Hoesing, L.M., White, S.N. 2013. A divergent artiodactyl MYADM-like repeat is associated with erythrocyte traits and weight of lamb weaned in domestic sheep. PLoS One. 8(8):e74700. doi: 10.1371/journal.pone.0074700.
Differential expression of three members of the multidomain adhesion CCp family in babesia bigemina, babesia bovis and theileria equi - (Peer Reviewed Journal)
Bastos, R., Suarez, C.E., Laughery, J., Johnson, W.C., Ueti, M.W., Knowles Jr, D.P. 2013. Differential expression of three members of the multidomain adhesion CCp family in babesia bigemina, babesia bovis and theileria equi. PLoS One. Plos ONE 8(7): e67765.
Identification and characterization of a genome-wide significant region associated with red blood cell phenotypes in domestic sheep - (Abstract Only)
Gonzalez, M.V., Mousel, M.R., Reynolds, J.O., Johnson, W.C., Herrmann-Hoesing, L.M., Lewis, G.S., Knowles Jr, D.P., White, S.N. 2012. Identification and characterization of a genome-wide significant region associated with red blood cell phenotypes in domestic sheep. Annual International Plant & Animal Genome Conference. Plant & Animal Genomes Conference XXI, Abstract 0617. San Diego, CA. January 14, 2013..
Ovine progressive pneumonia virus is transmitted more effectively via aerosol nebulization than oral administration - (Peer Reviewed Journal)
Herrmann-Hoesing, L.M., White, S.N., Neiswanger-Broughton, L.E., Johnson, W.C., Noh, S.M., Schneider, D.A., Li, H., Taus, N.S., Reynolds, J.O., Truscott, T.C., Dassanayake, R.P., Knowles Jr, D.P. 2012. Ovine progressive pneumonia virus is transmitted more effectively via aerosol nebulization than oral administration. Open Journal of Veterinary Medicine. 2(3):113-119.
A novel neutralization sensitive and subdominant RAP-1-related antigen (RRA) is expressed by babesia bovis merozoites - (Peer Reviewed Journal)
Suarez, C.E., Laughery, J., Bastos, R., Johnson, W.C., Norimine, J., Asenzo, G., Brown, W.C., Florin-Christensen, M., Goff, W.L. 2011. A novel neutralization sensitive and subdominant RAP-1-related antigen (RRA) is expressed by Babesia bovis merozoites. Parasitology. 10.1017/S0031182011000321.
Dynamics of bovine spleen cell populations during the response to acute Babesia bovis infection: an immunohistological study - (Peer Reviewed Journal)
Schneider, D.A., Yan, H., Bastos, R.G., Johnson, W.C., Gavin, P.R., Allen, A.J., Barrington, G.M., Hoesing, L.M., Knowles Jr, D.P., Goff, W.L. 2010. Dynamics of bovine spleen cell populations during the response to acute Babesia bovis infection: an immunohistological study. Parasite Immunology. Available: onlinelibrary.wiley.com/doi/10.1111/j.1365-3024.2010.01249.x/pdf.
The bovine spleen: Interactions among splenic cell populations in the innate immunologic control of hemoparasitic infections ()
Goff, W.L., Bastos, R.G., Brown, W.C., Johnson, W.C., Schneider, D.A. 2010. The bovine spleen: interactions among splenic cell populations in the innate immunologic control of hemoparasitic infections. Veterinary Immunology and Immunopathology. 138:1-14.
Validation of a Competitive Enzyme-Linked Immunosorbent Assay for Detection of Babesia bigemina Antibodies in Cattle - (Peer Reviewed Journal)
Goff, W.L., Johnson, W.C., Molloy, J.B., Jorgensen, W.K., Waldron, S.J., Figueroa, J.V., Matthee, O., Adams, D.S., Mcguire, T.C., Pino, I., Mosqueda, J., Palmer, G.H., Suarez, C.E., Knowles Jr, D.P., Mcelwain, T.F. 2008. Validation of a Competitive Enzyme-Linked Immunosorbent Assay for Detection of Babesia bigemina Antibodies in Cattle. Clinical and Vaccine Immunology. 15(9):1316-1321.
Bovine NK cells acquire cytotoxic activity and produce IFN-gamma after stimulation by Mycobacterium bovis BCG- or Babesia bovis-exposed splenic dendritic cells - (Peer Reviewed Journal)
Bastos, R.G., Johnson, W.C., Mwangi, W., Brown, W.C., Goff, W.L. 2008. Bovine NK cells acquire cytotoxic activity and produce IFN-gamma after stimulation by Mycobacterium bovis BCG- or Babesia bovis-exposed splenic dendritic cells. Veterinary Immunology and Immunopathology. 124:302-312.
Bovine WC1- gamma delta T-cells incubated with IL-15 express the natural cytotoxicity receptor CD335 (NKp46) and produce IFN-gamma in response to exogenous IL-12 and IL-18 - (Peer Reviewed Journal)
Johnson, W.C., Bastos, R.G., Davis, W.C., Goff, W.L. 2008. Bovine WC1- gamma delta T-cells incubated with IL-15 express the natural cytotoxicity receptor CD335 (NKp46) and produce IFN-gamma in response to exogenous IL-12 and IL-18. Developmental and Comparative Immunology. 32:1002-1010.
Differential response of splenic monocytes and DC from cattle to microbial stimulation with Mycobacterium bovis BCG and Babesia bovis merozoites - (Peer Reviewed Journal)
Bastos, R.G., Johnson, W.C., Brown, W.L., Goff, W.L. 2007. Differential response of splenic monocytes and DC from cattle to microbial stimulation with Mycobacterium bovis BCG and Babesia bovis merozoites. Veterinary Immunology and Immunopathology. 115(3-4):334-345.
Validation of a Competitive Enzyme-Linked Immunosorbent Assay for Detection of Antibodies against Babesia bovis - (Peer Reviewed Journal)
Goff, W.L., Molloy, J.B., Johnson, W.C., Suarez, C.E., Pino, I., Rhalem, A., Sahibi, H., Ceci, L., Carelli, G., Adams, D.S., Mcguire, T.C., Knowles Jr, D.P., Mcelwain, T.F. 2006. Validation of a Competitive Enzyme-Linked Immunosorbent Assay for Detection of Antibodies against Babesia bovis. Clinical and Vaccine Immunology. 13(11):1212-1216.
BOVINE SPLENIC NK CELLS SYNTHESIZE IFN-GAMMA IN RESPONSE TO IL-12-CONTAINING SUPERNATANTS FROM BABESIA BOVIS-EXPOSED MONOCYTE CULTURES - (Peer Reviewed Journal)
Goff, W.L., Storset, A.K., Johnson, W.C., Brown, W.C. 2006. Bovine splenic NK cells synthesize IFN-gamma in response to IL-12-containing supernatants from Babesia bovis-exposed monocyte cultures. Parasite Immunology. 28:221-228.
IMPROVED DIAGNOSTICS FOR EQUINE PIROPLASMOSIS SURVEILLANCE AND CONTROL PROGRAMS - (Proceedings)
Goff, W.L., Rhalem, A., Lasri, S., Johnson, W.C., Sahibi, H., Knowles Jr, D.P. 2006. Improved diagnostics for equine piroplasmosis surveillance and control programs. 9th Congress of the World Equine Veterinary Association. p.265-266.
THE INNATE IMMUNE RESPONSE TO CALVES IN BOOPHILUS MICROPLUS TICK TRANSMITTED BABESIA BOVIS INVOLVES TYPE-1 CYTOKINE INDUCTION AND NK-LIKE CELLS IN THE SPLEEN - (Peer Reviewed Journal)
Goff, W.L., Johnson, W.C., Horn, R.H., Barrington, G.M., Knowles Jr, D.P. 2003. The innate immune response to calves in boophilus microplus tick transmitted babesia bovis involves type-1 cytokine induction and nk-like cells in the spleen. Parasite Immunology. 25:185-188
COMPETITIVE ENZYME-LINKED IMMUNOSORBENT ASSAY BASED ON A RHOPTRY-ASSOCIATED PROTEIN 1 EPITOPE SPECIFICALLY IDENTIFIES BABESIA BOVIS-INFECTED CATTLE - (Peer Reviewed Journal)
Goff, W.L., McElwain, T.F., Suarez, C.E., Johnson, W.C., Brown, W.C., Norimine, J., Knowles, D.P. Competitive enzyme-linked immunosorbent assay based on a rhoptry-associated protein-1 epitope specifically identifies Babesia bovis-infected cattle. Clinical and Diagnostic Laboratory Immunology. 2002. v. 10. p. 38-43.
IL-4 AND IL-10 INHIBITION OF IFN-GAMMA AND TNF-ALPHA DEPENDENT NITRIC OXIDE PRODUCTION FROM BOVINE MONONUCLEAR PHAGOCYTES EXPOSED TO BABESIA BOVIS MEROZOITES - (Peer Reviewed Journal)
THE AGE RELATED INNATE IMMUNE RESPONSE IN CALVES TO BABESIA BOVIS INVOLVES IL-12 INDUCTION AND IL-10 MODULATION - (Peer Reviewed Journal)
THE ROLE OF IL-10 IN INOS AND CYTOKINE MRNA EXPRESSION DURING IN VITRO DIFFERENTIATION OF BOVINE MONONUCLEAR PHAGOCYTES - (Peer Reviewed Journal)
BABESIA BOVIS IMMUNITY: IN VITRO AND IN VIVO EVIDENCE FOR IL-10 REGULATION OF IFN-GAMMA AND INOS - (Peer Reviewed Journal)
BABESIA BOVIS: IDENTIFICATION OF MEROZOITE SURFACE PROTEINS IN SOLUBLE CULTURE DERIVED EXOANTIGEN - (Peer Reviewed Journal)
ASSESSMENT OF BOVINE MONONUCLEAR PHAGOCYTES AND NEUTROPHILS FOR INDUCED L-ARGININE-DEPENDENT NITRIC OXIDE PRODUCTION - (Peer Reviewed Journal)
ASSESSMENT OF BOVINE MONOCYTE/MACROPHAGES AND NEUTROPHILS FOR INDUCED L-ARGININE-DEPENDENT NITRIC OXIDE PRODUCTION - (Peer Reviewed Journal)
REACTIVE OXYGEN AND NITORGEN INTERMEDIATES AND PRODUCTS FROM POLYAMINE DEGRADATION ARE BABESIACIDAL IN VITRO - (Peer Reviewed Journal)
DEVELOPMENT OF CONVENTIONAL SUBUNIT VACCINES FOR ANAPLASMOSIS AND BABESIOSIS - (Peer Reviewed Journal)