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United States Department of Agriculture

Agricultural Research Service

Related Topics

Barbara Shukitt-Hale
Boston, Massachusetts
Psychology

Phone: (617) 556-3118
Fax: (617) 556-3222

USDA-ARS-HNRCA
711 WASHINGTON STREET
BOSTON , MA 021110000

Projects
The Effects of Raspberries on Inflammation, Psychomotor and Cognitive Behavior
General Cooperative Agreement (A)
  Accession Number: 430255
Effects of Tart Cherry Serum Metabolites on Stress-Induced Neurotoxicity in Brain Cells
General Cooperative Agreement (A)
  Accession Number: 430694
Effects of blackcurrant serum metabolites and PCSO-524 (PCSO) on stress-induced neurotoxicity in brain cells
General Cooperative Agreement (A)
  Accession Number: 430713
Nutrition, Brain, and Aging
Appropriated (D)
  Accession Number: 429012
Individual Differences in the Neurochemical and Behavioral Response to Exposure to Protons and HZE Particles
Interagency Reimbursable Agreement (I)
  Accession Number: 423720
Effects of Blackcurrant Serum Metabolites and PCSO-524 (PCSO) on Stress-Induced Neurotoxicity in Brain Cells
Interagency Reimbursable Agreement (I)
  Accession Number: 428466
Effects of Tart Cherry Serum Metabolites on Stress Induced Neurotoxicity in Brain Cells
Interagency Reimbursable Agreement (I)
  Accession Number: 430332
The Role of Strawberries in Aging: Effects of Strawberry Supplementation on Mobility and Cognition in Older Adults
Specific Cooperative Agreement (S)
  Accession Number: 429846
The Role of Strawberries in Aging: Effects of Strawberry Supplementation on Mobility and Cognition in Older Adults
Trust (T)
  Accession Number: 422734
The Effects of Raspberries on Inflammation, Psychomotor and Cognitive Behavior
Trust (T)
  Accession Number: 429308

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Berry fruit can improve age-associated neuronal and cognitive deficits: from the laboratory to the clinic -
Shukitt Hale, B., Miller, M.G., Thangthaeng, N., Fisher, D.R., Bielinski, D., Kelly, M.E., Tammy, S. 2016. Berry fruit can improve age-associated neuronal and cognitive deficits: from the laboratory to the clinic. American Aging Association. 72:61.
Preserving brain function in aging: The anti-glycative potential of berry fruit -
Thangthaeng, N., Poulose, S.M., Miller, M.G., Shukitt Hale, B. 2016. Preserving brain function in aging: the anti-glycative potential of berry fruit. NeuroMolecular Medicine. 18:465-473, doi: 10.1007/s12017-016-8400-3.
Dietary strawberry improves cognition in older adults: a randomized, double-blind, placebo-controlled study -
Miller, M.G., Thangthaeng, N., Scott, T.M., Shukitt Hale, B. 2016. Dietary strawberry improves cognition in older adults: a randomized, double-blind, placebo-controlled study. Federation of American Societies for Experimental Biology Conference. vol. 30 no. 1 Supplement 679.18.
Anthocyanin-rich blueberry diets enhance protection of critical brain regions exposed to acute levels of 56Fe cosmic radiation -
Poulose, S.M., Kelly, M.E., Bielinski, D.F., Miller, M.G., Rabin, B.M., Shukitt Hale, B. 2016. Anthocyanin-rich blueberry diets enhance protection of critical brain regions exposed to acute levels of 56Fe cosmic radiation. Federation of American Societies for Experimental Biology Conference. Vol. 30 No. 1 Supplement 679.4.
Red raspberries can improve motor function in aged rats -
Galli, R.L., Carey, A.N., Luskin, K.A., Bielinski, D.F., Shukitt Hale, B. 2016. Red raspberries can improve motor function in aged rats. Journal of Berry Research. 6:97-103.
Daily supplementation with mushroom (Agaricus bisporus) improves balance and working memory in aged rats -
Thangthaeng, N., Miller, M., Gomes, S., Shukitt Hale, B. 2015. Daily supplementation with mushroom (Agaricus bisporus) improves balance and working memory in aged rats. Nutrition Research. 35:1079-1084.
The beneficial effects of berries on cognition, motor behavior, and neuronal function in aging -
Shukitt Hale, B., Bielinski, D., Lau, F., Willis, L.M., Carey, A., Joseph, J. 2015. The beneficial effects of berries on cognition, motor behavior, and neuronal function in aging. British Journal of Nutrition. doi: 10.1017/S0007114515003451.
Effects of pterostilbene and resveratrol on brain and behavior -
Poulose, S.M., Thangthaeng, N., Miller, M.G., Shukitt Hale, B. 2015. Effects of pterostilbene and resveratrol on brain and behavior. Neurochemistry International. 89:227-233.
Comparison of the effectiveness of exposure to low LET helium particles (4He) and gamma rays (137Cs) on the disruption of cognitive performance -
Rabin, B.M., Carrihihll-Knoll, K.L., Shukitt Hale, B. 2015. Comparison of the effectiveness of exposure to low LET helium particles (4He) and gamma rays (137Cs) on the disruption of cognitive performance. Radiation Research. 184:266-272.
Effects of berry supplementation on mobility and cognition among older adults -
Miller, M.G., Shukitt Hale, B. 2015. Effects of berry supplementation on mobility and cognition among older adults. Berry Health Benefits Symposium, 2015 Berry Health Benefits Symposium Pre-Proceedings; October 13-15, 2015,Madison, Wisconsin, p. 24-25.
Effects of strawberry supplementation on mobility and cognition in older adults -
Miller, M.G., Thangthaeng, N., Scott, T.M., Shukitt Hale, B. 2015. Effects of strawberry supplementation on mobility and cognition in older adults. Society for Neuroscience Abstracts and Proceedings. Program #767.05.
Aging and walnut-rich diet supplementation affects the expression of immediate-early genes in critical brain regions -
Poulose, S.M., Bielinski, D.F., Crott, J.W., Roe, A.J., Thangthaeng, N., Shukitt Hale, B. 2015. Aging and walnut-rich diet supplementation affects the expression of immediate-early genes in critical brain regions. Society for Neuroscience Abstracts and Proceedings. Society for Neuroscience Abstracts 2015, Program #767.04.
Blueberries affect neuroinflammation and cognition differentially depending on individual cognitive baseline status -
Thangthaeng, N., Miller, M.G., Poulose, S.M., Bielinski, D.F., Fisher, D.R., Shukitt Hale, B. 2015. Blueberries affect neuroinflammation and cognition differentially depending on individual cognitive baseline status. Society for Neuroscience Abstracts and Proceedings. Society for Neuroscience Abstracts 2015, Program #767.03.
The effects of nutrition on cognition and motor function in aging -
(Program Booklet) Nutraceuticals in Neurodegeneration and Aging, Satellite meeting to the 25th ISN-13th APSN Biennial Meeting, 2015 (no page numbers exist)Shukitt Hale, B. 2015. The effects of nutrition on cognition and motor function in aging. Meeting Abstract.
Polyphenols found in berry fruit improve age-associated changes in cognitive function and brain inflammation -
Shukitt Hale, B. 2015. Polyphenols found in berry fruit improve age-associated changes in cognitive function and brain inflammation. Polyphenols Actualites [abstract]. 7th International Conference on Polyphenols and Health (Program), p. 50.
Acute effects of exposure to 56Fe and 16O particles on learning and memory -
Rabin, B.M., Poulose, S.M., Carrihill-Knoll, K.L., Ramirez, F., Bielinski, D.F., Heroux, N., Shukitt Hale, B. 2015. Acute effects of exposure to 56Fe and 16O particles on learning and memory. Radiation Research. 184:143-150.
Walnuts improve neuronal and behavioral function in aging -
Shukitt Hale, B., Thangthaeng, N., Fisher, D.R., Bielinski, D.F., Poulose, S.M. 2015. Walnuts improve neuronal and behavioral function in aging. Federation of European Nutrition Societies European Nutrition Conference. Annals of Nutrition and Metabolism. Vol. 67 (Suppl. 1) p. 463.
Effect of blueberries and insulin on glucose induced neurotoxicity in brain cells in vitro -
Hininger-Favier, I., Thangthaeng, N., Shukitt Hale, B., Poulose, S. 2015. Effect of blueberries and insulin on glucose induced neurotoxicity in brain cells in vitro. Federation of European Nutrition Societies European Nutrition Conference. Annals of Nutrition and Metabolism (2015), vol 67 (Suppl.1), p. 467-468.
Lack of reliability in the disruption of cognitive performance following exposure to protons -
Rabin, B.M., Heroux, N.A., Shukitt Hale, B., Carrihill-Knoll, K.L., Beck, Z., Baxter, C. 2015. Lack of reliability in the disruption of cognitive performance following exposure to protons. Radiation and Environmental Biophysics. 54:285-295.
Effects of dietary blueberry on cognition and in vivo and in vitro inflammatory status -
Miller, M.G., Fisher, D.R., Kelly, M.E., Bielinski, D.F., Shukitt Hale, B. 2015. Effects of dietary blueberry on cognition and in vivo and in vitro inflammatory status. Federation of American Societies for Experimental Biology Conference. 29:900.2.
Effects of aging and walnut diet on DNA methylation and expression of immediate-early genes in critical brain regions -
Poulose, S.M., Bielinski, D.F., Crott, J.W., Roe, A.J., Thangthaeng, N., Shukitt Hale, B. 2015. Effects of aging and walnut diet on DNA methylation and expression of immediate-early genes in critical brain regions. Federation of American Societies for Experimental Biology Conference. FASEB Journal - EB abstracts 2015.
Differential effects of blueberry polyphenols on age-associated neuroinflammation and cognition -
Thangthaeng, N., Miller, M.G., Poulose, S.M., Bielinski, D.F., Fisher, D.R., Shukitt Hale, B. 2015. Differential effects of blueberry polyphenols on age-associated neuroinflammation and cognition. Federation of American Societies for Experimental Biology Conference. 29:756-758.
Protective effects of blueberry and strawberry diets on neuronal stress following exposure to 56Fe particles -
Poulose, S.M., Bielinski, D., Carrihill-Knoll, K.L., Rabin, B.M., Shukitt Hale, B. 2014. Protective effects of blueberry and strawberry diets on neuronal stress following exposure to 56Fe particles. Brain Research. 1593:9-18.
Serum metabolites from walnut-fed aged rats attenuate stress-induced neurotoxicity in BV-2 microglial cells -
Fisher, D.R., Poulose, S.M., Bielinski, D.F., Shukitt Hale, B. 2014. Serum metabolites from walnut-fed aged rats attenuate stress-induced neurotoxicity in BV-2 microglial cells. Nutritional Neuroscience. DOI: http://dx.doi.org/10.1179/1476830514Y.0000000150.
Effects of age on the disruption of cognitive performance by exposure to space radiation -
Rabin, B., Shukitt Hale, B., Carrihill-Knoll, K. 2014. Effects of age on the disruption of cognitive performance by exposure to space radiation. Journal of Behavioral and Brain Science. 4:297-307.
Mobility and cognition: End points for dietary interventions in aging -
Miller, M.G., Hamilton, D.A., Joseph, J.A., Shukitt Hale, B. 2014. Mobility and cognition: End points for dietary interventions in aging. Nutrition and Aging. 2:213-222.
Serum metabolites from blueberry-supplemented older adults attenuate stress-induced neurotoxicity in HAPI microglial cells dependent on baseline cognitive status -
Shukitt Hale, B., Miller, M.G., Fisher, D.R. 2014. Serum metabolites from blueberry-supplemented older adults attenuate stress-induced neurotoxicity in HAPI microglial cells dependent on baseline cognitive status. Society for Neuroscience Abstracts and Proceedings. 2014. Program #144.16.
Acute effects of exposure to space radiation on CNS function and cognitive performance -
Rabin, B.M., Shukitt Hale, B., Carrihill-Knoll, K.L., Bielinski, D.F., Poulose, S.M., Heroux, N.A., Baxter, C. 2014. Acute effects of exposure to space radiation on CNS function and cognitive performance. Society for Neuroscience Abstracts and Proceedings. 2014. Program #559.13.
Effects of dietary blueberry supplementation on older adults -
Miller, M.G., Joseph, J.A., Shukitt Hale, B. 2014. Effects of dietary blueberry supplementation on older adults. Society for Neuroscience Abstracts and Proceedings. 2014 Program #144.19.
Tart cherry extracts reduce inflammatory stress signaling and enhance calcium buffering in microglial and neuronal cell lines -
Fisher, D.R., Bielinski, D., Kelly, M.E., Shukitt Hale, B. 2014. Tart cherry extracts reduce inflammatory stress signaling and enhance calcium buffering in microglial and neuronal cell lines. Society for Neuroscience Abstracts and Proceedings 2014. Program #144.18.
Walnut extracts protect cultured microglia against LPS-induced neurotoxicity via modulation of intracellular calcium concentration -
Thangthaeng, N., Poulose, S., Fisher, D.R., Shukitt Hale, B. 2014. Walnut extracts protect cultured microglia against LPS-induced neurotoxicity via modulation of intracellular calcium concentration. Society for Neuroscience Abstracts and Proceedings. 2014. Program #144.17.
Cognition: the new frontier for nuts and berries -
Pribis, P., Shukitt Hale, B. 2014. Cognition: the new frontier for nuts and berries. American Journal of Clinical Nutrition. 100(suppl):347S–352S.
Cerebral blood volume and vasodilation are independently diminished by aging and hypertension: A near infrared spectroscopy study -
Differential protective effects of serum metabolites from young and old walnut-fed rats against stress-induced neurotoxicity in BV-2 microglial cells -
Shukitt Hale, B., Fisher, D.R., Bielinski, D.F., Poulose, S.M. 2014. Differential protective effects of serum metabolites from young and old walnut-fed rats against stress-induced neurotoxicity in BV-2 microglial cells. [abstract]. American Aging Association. 127:73.
Effects of dietary blueberry supplementation on older adults -
Miller, M.G., Joseph, J.A., Shukitt Hale, B. 2014. Effects of dietary blueberry supplementation on older adults [abstract]. American Aging Association. Paper # 75, p. 53.
A voyage to Mars: space radiation, aging, and nutrition -
Rabin, B., Shukitt Hale, B. 2014. A voyage to Mars: space radiation, aging, and nutrition. Nutrition and Aging. 2:233-241.
Blueberry supplementation improves memory in middle-aged mice fed a high-fat diet -
Carey, A.N., Gomes, S.M., Shukitt Hale, B. 2014. Blueberry supplementation improves memory in middle-aged mice fed a high-fat diet. Journal of Agricultural and Food Chemistry. 62:3972-3978.
Comparison of the effects of partial-or-whole-body exposures to 16O particles on cognitive performance in rats -
Rabin, B.M., Shukitt Hale, B., Carrihill-Knoll, K.L. 2014. Comparison of the effects of partial-or-whole-body exposures to 16O particles on cognitive performance in rats. Radiation Research. 181:251-257.
Cognitive effects of partial and whole body exposures to 160 particles -
Rabin, B., Shukitt Hale, B., Gomes, S., Carrihill-Knoll, K. 2014. Cognitive effects of partial and whole body exposures to 160 particles. Journal of Radiation Research. 55:100-101. DOI: 10.1093/jrr/rrt187.
Neuronal stress following exposure to 56Fe particles and the effects of antioxidant-rich diets -
Poulose, S.M., Bielinski, D., Carrihill-Knoll, K., Rabin, B., Shukitt Hale, B. 2014. Neuronal stress following exposure to 56Fe particles and the effects of antioxidant-rich diets. Journal of Radiation Research. 55:73-74. DOI: 10.1093/jrr/rrt155.
Restoration of stressor-induced calcium dysregulation and autophagy inhibition by polyphenol-rich acai (Euterpe sps.) fruit pulp extracts in rodent brain cells in vitro -
Poulose, S.M., Fisher, D.R., Bielinski, D., Gomes, S., Rimando, A., Schauss, A., Shukitt Hale, B. 2014. Restoration of stressor-induced calcium dysregulation and autophagy inhibition by polyphenol-rich acai (Euterpe sps.) fruit pulp extracts in rodent brain cells in vitro. Nutrition. 30: 853-862.
Role of walnuts in maintaining brain health with age -
Poulose, S.M., Miller, M.G., Shukitt Hale, B. 2014. Role of walnuts in maintaining brain health with age. Journal of Nutrition. 144 (4 Suppl):561S-566S.
Tart cherries improve working memory in aged rats -
Shukitt Hale, B., Miller, M.G., Bielinski, D.F., Poulose, S.M. 2013. Tart cherries improve working memory in aged rats. Society for Neuroscience Abstracts and Proceedings. 2013. Program # 252.03.
Performance deficit produced by partial body exposures to space radiation -
Rabin, B.M., Shukitt Hale, B., Carrihill-Knoll, K.L., Gomes, S., Heroux, N. 2013. Performance deficit produced by partial body exposures to space radiation. Society for Neuroscience Abstracts and Proceedings. 2013. Program #445.06.
Cognitive effects of proton irradiation at differing energy levels -
Heroux, N., Carrihill-Knoll, K., Rabin, B.M., Shukitt Hale, B. 2013. Cognitive effects of proton irradiation at differing energy levels. Society for Neuroscience Abstracts and Proceedings. 2013. Program # 766.15.
Dietery acai fruit improves cognition in aged rats -
Miller, M.G., Fisher, D.R., Carey, A.N., Poulose, S.M., Shukitt Hale, B. 2013. Dietery acai fruit improves cognition in aged rats. Society for Neuroscience Abstracts and Proceedings. 2013. Program # 252.04.
Dietery walnut alters neurochemical and behavioral functions in young and old rats -
Poulose, S.M., Fisher, D.R., Miller, M.M., Bielinski, D.F., Ramirez, F., Shukitt Hale, B. 2013. Dietery walnut alters neurochemical and behavioral functions in young and old rats. Society for Neuroscience Abstracts and Proceedings. 2013. Program #252.02.
Stilbenes and anthocyanins reduce stress signaling in BV-2 mouse microglia -
Carey, A.N., Fisher, D.R., Rimando, A.M., Gomes, S.M., Bielinski, D.F., Shukitt Hale, B. 2013. Stilbenes and anthocyanins reduce stress signaling in BV-2 mouse microglia. Journal of Agricultural and Food Chemistry. 61: 5979-5986.
Overview of the health properties of blueberries -
Elks, C.M., Francis, J., Stull, A.J., Cefalu, W.T., Shukitt Hale, B., Ingram, D.K. 2013. Overview of the health properties of blueberries. In: Skinner, M and Hunter D. editors. Bioactives in Fruit: Health Benefits and Functional Food. Hoboken, NJ. Wiley-Blackwell. p. 251-271.
Assessment of berry fruit's effects on mobility and cognition in aging -
Shukitt Hale, B., Miller, M. 2013. Assessment of berry fruit's effects on mobility and cognition in aging. American Aging Association. 42nd Annual Meeting, Pre-conference, Aging and Nutrition Program, Aging: Prevention, Reversal and Slowing. Abstract #2, p. 31.
Berry effects on cognition and motor function in aging -
Shukitt Hale, B., Miller, M. 2013. Berry effects on cognition and motor function in aging. Berry Health Benefits Symposium. 2013 Pre-Proceedings, p. 33.
Effect of berries on cognitive and neurochemical functions -
Poulose, S.M., Shukitt Hale, B. 2013. Effect of berries on cognitive and neurochemical functions. Meeting Abstract. First International Symposium on Elderberry Proceedings, p. 50.
Neuronal stress following exposure to 56Fe particles and the effects of antioxidant-rich diets -
Poulose, S.M., Bielinski, D.F., Carrihill-Knoll, K.L., Rabin, B.M., Shukitt Hale, B. 2013. Neuronal stress following exposure to 56Fe particles and the effects of antioxidant-rich diets. Heavy Ion in Therapy and Space Radiation Symposium Program & Abstracts, Session #NASA-01, p. 49.
Nutritional interventions protect against age-related deficits in behavior: from animals to humans -
Shukitt Hale, B., Miller, M.G. 2013. Nutritional interventions protect against age-related deficits in behavior: from animals to humans. Federation of American Societies for Experimental Biology Conference. Abstract 27:862.10.
Blueberry supplementation improves memory in middle-aged mice consuming a high fat diet -
Carey, A.N., Shukitt Hale, B. 2013. Blueberry supplementation improves memory in middle-aged mice consuming a high fat diet. Federation of American Societies for Experimental Biology Conference. Abstract 27:1083.5.
Blueberries and strawberries activate neuronal housekeeping in critical brain regions of stress-induced young rats -
Poulose, S.M., Bielinski, D.F., Carrihill-Knoll, K., Rabin, B.M., Shukitt Hale, B. 2013. Blueberries and strawberries activate neuronal housekeeping in critical brain regions of stress-induced young rats. Federation of American Societies for Experimental Biology Conference. Abstract 27:637.39.
Dietary acai fruit improves cognition and mobility in aged rats -
Miller, M.G., Fisher, D.R., Carey, A.N., Poulose, S.M., Shukitt Hale, B. 2013. Dietary acai fruit improves cognition and mobility in aged rats. Federation of American Societies for Experimental Biology Conference. Abstract 27:1083.3.
Effects of 17Beta-estradiol on cognitive performance of ovariectomized female rats exposed to 56Fe particles -
Rabin, B., Carrihill-Knoll, K., Long, L., Pitts, S., Shukitt Hale, B. 2013. Effects of 17Beta-estradiol on cognitive performance of ovariectomized female rats exposed to 56Fe particles. Journal of Behavioral and Brain Science. 3:67-73.
Coffee, but not caffeine, has positive effects on cognition and psychomotor behavior in aging Reprint Icon -
Shukitt Hale, B., Miller, M.G., Chu, Y., Lyle, B., Joseph, J. 2013. Coffee, but not caffeine, has positive effects on cognition and psychomotor behavior in aging. Age. 35:2183-2192.
Walnuts and Berries for the Brain -
Shukitt Hale, B. 2013. Walnuts and Berries for the Brain. The 6th International Congress on Vegetarian Nutrition Progam #2, p.30.
Changes in gene expression in the rat hippocampus following exposure to 56 fe particles and protection by berry diets -
Shukitt Hale, B., Lau, F., Cheng, V., Luskin, K., Carey, A., Carrihill-Knoll, K., Rabin, B., Joseph, J.A. 2013. Changes in gene expression in the rat hippocampus following exposure to 56 fe particles and protection by berry diets. Central Nervous System Agents in Medicinal Chemistry. 13:36-42.
Functional role of walnuts and acai fruits on brain health -
Poulose, S.M., Shukitt Hale, B. 2013. Functional role of walnuts and acai fruits on brain health. IN: Patil, B.S., Jayaprakasha, G.K., Roa, C.O., Mahattanatawee, K. Eds. Tropical and Subtropical Fruits. American Chemical Society Publications, Washington DC. p.171-187.
Berry fruit and nuts: their role in reducing oxidative stress and inflammation in the aging brain -
Miller, M.G., Shukitt Hale, B., Joseph, J.A. 2012. Berry fruit and nuts: their role in reducing oxidative stress and inflammation in the aging brain. In: Carkeet, C., Grann, K., Randolph, R. K., Venzon, D.S., Izzy, S. Phytochemicals: Health Promotion and Therapeutic Potential. CRC Press. p. 181-204.
Acai fruit improves motor and cognitive function in aged rats -
Shukitt Hale, B., Carey, A.N., Miller, M., Poulose, S.M. 2012. Acai fruit improves motor and cognitive function in aged rats [abstract]. Society for Neuroscience Abstracts and Proceedings. Paper No. 865:04.
The effects of blueberry supplementation in middle aged mice consuming a high fat diet -
Carey, A.N., Shukitt Hale, B. 2012. The effects of blueberry supplementation in middle aged mice consuming a high fat diet [abstract]. Society for Neuroscience Abstracts and Proceedings. Paper No. 865:01.
Human cognition and mobility in aging: a model for berry fruit interventions -
Miller, M., Shukitt Hale, B. 2012. Human cognition and mobility in aging: a model for berry fruit interventions [abstract]. Society for Neuroscience Abstracts and Proceedings. Paper No. 865:03.
Sex differences in operant responding and survivability following exposure to space radiation -
Carrihill-Knoll, K., Rabin, B., Shukitt Hale, B. 2012. Sex differences in operant responding and survivability following exposure to space radiation [abstract]. Society for Neuroscience Abstracts and Proceedings. 915:14.
Serum metabolites from walnut-fed aged rats attenuate stress-induced neurotoxicity in brain cells in vitro -
Poulose, S.M., Fisher, D.R., Bielinski, D., Shukitt Hale, B. 2012. Serum metabolites from walnut-fed aged rats attenuate stress-induced neurotoxicity in brain cells in vitro [abstract]. Society for Neuroscience Abstracts and Proceedings. Paper No. 865:02.
Blueberries and neuronal aging -
Shukitt Hale, B. 2012. Blueberries and neuronal aging. Gerontology Journal. 58:518-523.
Walnut diet reduces accumulation of polyubiquitinated proteins and inflammation in the brain of aged rats -
Poulose, S., Bielinski, D., Shukitt Hale, B. 2012. Walnut diet reduces accumulation of polyubiquitinated proteins and inflammation in the brain of aged rats. Journal of Nutritional Biochemistry. DOI: 10.1016/j.jnutbio.2012.06.09.
Improving brain signaling in aging: could berries be the answer? -
Poulose, S.M., Carey, A.N., Shukitt Hale, B. 2012. Improving brain signaling in aging: could berries be the answer?. Popular Publication. 8:887-889.
The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells -
Carey, A.N., Fisher, D.R., Joseph, J.J., Shukitt Hale, B. 2013. The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells. Nutritional Neuroscience. 16(1):13-20.
The beneficial effects of tree nuts on the aging brain -
Carey, A.N., Poulose, S.M., Shukitt Hale, B. 2012. The beneficial effects of tree nuts on the aging brain. Nutrition and Aging. 1:55-67.
Berry fruit enhances beneficial signaling in brain -
Miller, M., Shukitt Hale, B. 2012. Berry fruit enhances beneficial signaling in brain. Journal of Agricultural and Food Chemistry. 60:5709-5715.
Anthocyanin-rich acai (Euterpe oleracea mart.) fruit pulp fractions attenuate inflammatory stress signaling in mouse brain BV-2 microglial cells -
Poulose, S.M., Fisher, D.R., Larson, J., Bielinski, D.F., Rimando, A.M., Carey, A.N., Schauss, A.G., Shukitt Hale, B. 2012. Anthocyanin-rich acai (Euterpe oleracea mart.) fruit pulp fractions attenuate inflammatory stress signaling in mouse brain BV-2 microglial cells. Journal of Agricultural and Food Chemistry. 60:1084-1093.
Dietary supplementation with coffee improves motor and cognitive performance in aged rats -
Carey, A.N., Shukitt Hale, B. 2011. Dietary supplementation with coffee improves motor and cognitive performance in aged rats [abstract]. Gerontological Society of America. Program No. 955-17.
Effects of flavonoids on cognitive performance -
Poulose, S.M., Shukitt Hale, B. 2012. Effects of flavonoids on cognitive performance. In: Spencer, J., Crozier, A., editors. Flavonoids and Related Compounds: Bioavailability and Function. United Kingdom: Taylor and Francis Group LLC, CRC Press. p. 393-411.
The behavioral and neuronal signaling benefits of polyphenols -
Shukitt Hale, B. 2011. The behavioral and neuronal signaling benefits of polyphenols. 5th International Conference on Polyphenols and Health [abstract}. Abstract No. 068.
Coffee and Alzheimer’s disease - animal & cellular evidences -
Miller, M.G., Shukitt Hale, B. 2012. Coffee and Alzheimer’s disease - animal & cellular evidences. In: Chu, YiFang, editor. Coffee: Emerging Health Effects and Disease Prevention. New York, NY: John Wiley. p. 77-96.
Exposure to O-16 particle irradiation causes age-like decrements in rats through increased oxidative stress, inflammation and loss of autophagy -
Poulose, S.M., Bielinski, D., Carrihill-Knoll, K., Rabin, B.M., Shukitt Hale, B. 2011. Exposure to O-16 particle irradiation causes age-like decrements in rats through increased oxidative stress, inflammation and loss of autophagy.Radiation Research. 176:761-769.
Low-dose pterostilbene but not resveratrol is a potent neuromodulator in aging and Alzheimer’s Disease -
Chang, J., Rimando, A.M., Pallas, M., Camins, A., Porquet, D., Reeves, J., Shukitt Hale, B., Smith, M.A., Joseph, J.A., Casadesus, G. 2011. Low-dose pterostilbene but not resveratrol is a potent neuromodulator in aging and Alzheimer’s Disease. Neurobiology of Aging. 33:2062-2071.
A blueberry enriched diet attenuates nephropathy in a rat model of hypertension via reduction in oxidative stress -
Elks, C.M., Mariappan, N., Shukitt Hale, B., Joseph, J.A., Ingram, D.K., Francis, J. 2011. A blueberry enriched diet attenuates nephropathy in a rat model of hypertension via reduction in oxidative stress. PLoS One. 6(9)e24028.
Food for thought: what Jim Joseph taught me about aging and nutrition -
Operant responding following exposure to HZE particles and its relationship to particle energy and LET -
Rabin, B.M., Carrihill-Knoll, K., Shukitt Hale, B. 2011. Operant responding following exposure to HZE particles and its relationship to particle energy and LET. Advances in Space Research. 48:370-377.
Interaction between age of irradiation and age of testing in the disruption of operant performance using a ground-based model for exposure to cosmic rays -
Rabin, B.M., Joseph, J.A., Shukitt Hale, B., Carrihill-Knoll, K. 2012. Interaction between age of irradiation and age of testing in the disruption of operant performance using a ground-based model for exposure to cosmic rays. American Aging Association. 34:121-131.
Short-term nutritional folate deficiency in rats has a greater effect on choline and acetylcholine metabolism in the peripheral nervous system than in the brain, and this effect escalates with age -
Crivello, N., Blusztajn, J., Joseph, J.A., Shukitt Hale, B., Smith, D. 2010. Short-term nutritional folate deficiency in rats has a greater effect on choline and acetylcholine metabolism in the peripheral nervous system than in the brain, and this effect escalates with age. Nutrition Research. 30(10):722-730.
Differential protection among fractionated blueberry polyphenolic families against DA-, ABeta 42 and LPS-induced decrements in Ca2+ buffering in primary hippocampal cells -
Joseph, J.A., Shukitt Hale, B., Brewer, G.J., Weikel, K.A., Kalt, W., Fisher, D.R. 2010. Differential protection among fractionated blueberry polyphenolic families against DA-, ABeta 42 and LPS-induced decrements in Ca2+ buffering in primary hippocampal cells. Journal of Agriculture and Food Chemistry. 58:8196-8204.
Short-term blueberry-enriched antioxidant diet prevents and reverses object recognition memory loss in aged rats -
Malin, D.H., Lee, D.R., Goyarzu, P., Chang, Y., Ennis, L.J., Beckett, E., Shukitt Hale, B., Joseph, J.A. 2011. Short-term blueberry-enriched antioxidant diet prevents and reverses object recognition memory loss in aged rats. Nutrition. 27:338-342.
Blueberry supplementation improves memory in older adults -
Krikorian, R., Shidler, M., Nash, T., Kalt, W., Vinqvist-Tymchuk, M., Shukitt Hale, B., Joseph, J.A. 2010. Blueberry supplementation improves memory in older adults. Journal of Agricultural and Food Chemistry. 58:3996-4000.
Survival and cardioprotective benefits of long-term blueberry enriched diet in dilated cardiomyopathy following myocardial infarction in rats -
Ismayil, A., Spangler, E., Shukitt Hale, B., Joseph, J.A., Ingram, D., Talan, M. 2009. Survival and cardioprotective benefits of long-term blueberry enriched diet in dilated cardiomyopathy following myocardial infarction in rats. PLoS One. 4(11):e7975.
Concord Grape Juice Supplementation Improves Memory Function In Older Adults with Mild Cognitive Impairment -
Krikorian, R., Nash, T.A., Shidler, M.D., Shukitt Hale, B., Joseph, J.A. 2009. Concord Grape Juice Supplementation Improves Memory Function In Older Adults with Mild Cognitive Impairment. British Journal of Nutrition. 103:730-734.
Dietary polyunsaturated fatty acids improve cholinergic transmission in the aged brain -
Willis, L., Shukitt Hale, B., Joseph, J.A. 2009. Dietary polyunsaturated fatty acids improve cholinergic transmission in the aged brain. Genes and Nutrition. 4:309-314.
Fruits, Nuts, and Brain Aging: Nutritional Interventions Targeting Age-Related Neuronal and Behavioral Deficits -
Joseph, J.A., Shukitt Hale, B., Willis, L. 2009. Fruits, Nuts, and Brain Aging: Nutritional Interventions Targeting Age-Related Neuronal and Behavioral Deficits. In: Packer, L., Sies, H., Eggersdorfer, M., and Cadenas, E., editors. Micronutrients and Brain Health. Boca Raton, FL: CRC Press. p. 179-188.
Blueberry-enriched diet protects rat heart from ischemic damage -
Ahmet, I., Spangler, E., Shukitt Hale, B., Juhaszova, M., Sollott, S.J., Joseph, J.A., Ingram, D.K., Talan, M. 2009. Blueberry-enriched diet protects rat heart from ischemic damage. PLoS One. 4(5934):1-10.
Grape juice, berries and walnuts affect brain aging and behavior -
Joseph, J.A., Shukitt Hale, B., Willis, L. 2009. Grape juice, berries and walnuts affect brain aging and behavior. Journal of Nutrition. 139:1813S-1817S.
Mitigation of oxidative stress and inflammatory signaling by fruit and walnut polyphenols: implications for cognitive aging -
Joseph, J.J., Shukitt Hale, B., Willis, L. 2010. Mitigation of oxidative stress and inflammatory signaling by fruit and walnut polyphenols: implications for cognitive aging. In: Santos-Buelga, C., Escribano-Bailon, M., Lattanzio V., editors. Recent Advances in Polyphenol Research. Volume 2. Oxford, England: Blackwell Publishing Ltd. 2:283-293.
Modulation of cognition and behavior in aged animals: role of antioxidant and essential fatty acid rich plant foods -
Willis, L., Shukitt Hale, B., Joseph, J.A. 2009. Modulation of cognition and behavior in aged animals: role of antioxidant and essential fatty acid rich plant foods. American Journal of Clinical Nutrition. 89:1602S-1606S.
Effects of Blackberries on Motor and Cognitive Function in Aged Rats -
Shukitt Hale, B., Cheng, V., Joseph, J.A. 2009. Effects of Blackberries on Motor and Cognitive Function in Aged Rats. Nutritional Neuroscience.12:135-140.
Effects of heavy particle irradiation on diet on object recognition memory in rats -
Rabin, B.M., Carrihill-Knoll, K., Hinchman, M., Shukitt Hale, B., Joseph, J.A., Foster, B.C. 2009. Effects of heavy particle irradiation on diet on object recognition memory in rats. Advances in Space Research. 43:1193-1199.
Plum Juice, but Not Dried Plum Powder, is Effective in Mitigating Cognitive Deficits in Aged Rats -
Shukitt Hale, B., Kalt, W., Carey, A., Vinqvist-Tymchuk, M., Mcdonald, J., Joseph, J.A. 2009. Plum Juice, but Not Dried Plum Powder, is Effective in Mitigating Cognitive Deficits in Aged Rats. Nutrition.25:567-573.
Recent Advances in Berry Supplementation and Age-Related Cognitive Decline -
Willis, L., Shukitt Hale, B., Joseph, J.A. Recent Advances in Berry Supplementation and Age-Related Cognitive Decline. Current Opinion in Clinical Nutrition and Metabolic Care. 2009. 12:91-94.
Cellular and Behavioral Effects of Stilbene Resveratrol Analogs: Implications for Reducing the Deleterious Effects of Aging -
Joseph, J.A., Fisher, D.R., Cheng, V., Rimando, A.M., Shukitt Hale, B. 2008. Cellular and Behavioral Effects of Stilbene Resveratrol Analogs: Implications for Reducing the Deleterious Effects of Aging. Journal of Agriculture and Food Chemistry.56(22)10544-10551.
Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by methionine without lowering homocysteine -
Troen, A.M., Chao, W., Crivello, N.A., Shukitt Hale, B., Smith, D., Selhub, J., Rosenberg, I. 2008. Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by methionine without lowering homocysteine. Journal of Nutrition. 138(12):2502-2509.
Dose-Dependent Effects of Walnuts on Motor and Cognitive Function in Aged Rats -
Willis, L., Shukitt Hale, B., Cheng, V., Joseph, J.A. 2009. Dose-Dependent Effects of Walnuts on Motor and Cognitive Function in Aged Rats. British Journal of Nutrition. 101:1140-1144.
B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice -
Troen, A.M., Shea-Budgell, M., Shukitt Hale, B., Smith, D., Selhub, J., Rosenberg, I. 2008. B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice. Proceedings of the National Academy of Sciences. 105(34):12474-12479.
Effects of Berry Fruits on Neurocognitive Deficits Produced by Exposure to Space Radiation -
Rabin, B.M., Joseph, J.A., Shukitt Hale, B. 2008. Effects of Berry Fruits on Neurocognitive Deficits Produced by Exposure to Space Radiation. In: Arora, R. Herbal Radiomodulators Applications in Medicine, Homeland Defence and Space. Wallingford, UK: Institute of Nuclear Medicine and Allied Sciences. p.151-161.
Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus -
Shukitt Hale, B., Lau, F.C., Carey, A.N., Galli, R.L., Spangler, E.L., Ingram, D.K., Joseph, J.A. 2008. Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus. Nutritional Neuroscience. 11(4):172-182.
"Brainberries" and Aging -
Joseph, J.A., Shukitt Hale, B. 2008. "Brainberries" and Aging. Clinical Nutrition Insight.34:1-4.
Berry Fruit Supplementation in the Aging Brain -
Shukitt Hale, B., Lau, F.C., Joseph, J.A. 2008. Berry Fruit Supplementation in the Aging Brain. Journal of Agriculture and Food Chemistry. 56:636-641.
Polyphenols and Polyunsaturate Fatty Acids: The Pollyanna's of Age-Related Cognitive Decline, Neurodegenerative Disease -
Joseph, J.A., Smith, M.A., Perry, G., Shukitt Hale, B. 2008. Polyphenols and Polyunsaturate Fatty Acids: The Pollyanna's of Age-Related Cognitive Decline, Neurodegenerative Disease. In Coulston, A.M. and Boushey, C.J., editors. Nutrition in the Prevention and Treatment of Disease. 2nd edition. San Diego: Elsevier. p. 269-287.
Blueberries and Human Health: A Review of Current Research -
Kalt, W., Joseph, J.A., Shukitt Hale, B. 2007. Blueberries and Human Health: A Review of Current Research. Journal of American Pomological Society. 61:151-160.
Aging modifies brain region-specific vulnerability to experimental oxidative stress induced by low dose hydrogen peroxide -
Denissova, N., Rosenberg, I., Shukitt Hale, B., Bielinski, D., Dallal, G., Joseph, J.A. 2007. Aging modifies brain region-specific vulnerability to experimental oxidative stress induced by low dose hydrogen peroxide. American Aging Association. 29:191-203.
Dietary modulation of the effects of exposure to 56FE particles -
Rabin, B.M., Joseph, J.A., Shukitt Hale, B., Carey, A.N. 2007. Dietary modulation of the effects of exposure to 56FE particles. Advances in Space Research. 40(4):576-580.
A blueberry-enriched diet provides cellular protection against oxidative stress and attenuates a kainate-induced learning impairment in rats -
Duffy, K.B., Spangler, E.L., Devan, B.D., Guo, Z., Bowker, J.L., Janas, A.M., Hagapanos, A., Minor, R.K., Decabo, R., Mouton, P.R., Shukitt Hale, B., Joseph, J.A., Ingram, D.K. 2008. A blueberry-enriched diet provides cellular protection against oxidative stress and attenuates a kainate-induced learning impairment in rats. Neurobiology of Aging. 29:1680-1689.
Amphetamine-Induced Taste Aversion Learning in Young and Old F-344 Rats Following Exposure to 56Fe Particles -
Carrihill-Knoll, K.L., Rabin, B.M., Shukitt Hale, B., Joseph, J.A., Carey, A. 2007. Amphetamine-Induced Taste Aversion Learning in Young and Old F-344 Rats Following Exposure to 56Fe Particles. Pharmacology, Biochemistry and Behavior. 29(2):69-76.
Fruit Polyphenols and their effects on Neuronal Signaling and Behavior in Senescence. -
Joseph, J.A., Shukitt Hale, B., Lau, F.C. 2007. Fruit Polyphenols and their effects on Neuronal Signaling and Behavior in Senescence. Annals of the New York Academy of Sciences. 1100:470-485.
Interaction between age and exposure to 56Fe particles on behavior and neurochemistry -
Carey, A.N., Shukitt Hale, B., Rabin, B.M., Joseph, J.A. 2007. Interaction between age and exposure to 56Fe particles on behavior and neurochemistry. Advances in Space Research. 39:987-993.
Elevated plus-maze performance of Fischer-344 rats as a function of age and of exposure to 56Fe particles -
Rabin, B.M., Carrihill-Knoll, K.L., Carey, A.N., Shukitt Hale, B., Joseph, J.A., Foster, B.C. 2007. Elevated plus-maze performance of Fischer-344 rats as a function of age and of exposure to 56Fe particles. Advances in Space Research. 39:981-986.
Exposure to 56Fe irradiation accelerates normal brain aging and produces deficits in spatial learning and memory -
Shukitt Hale, B., Casadesus, G., Carey, A.N., Rabin, B.M., Joseph, J.A. 2007. Exposure to 56Fe irradiation accelerates normal brain aging and produces deficits in spatial learning and memory. Advances in Space Research. 39:1087-1092.
Nutritional Intervention in Brain Aging: Reducing the Effects of Inflammation and Oxidative Stress -
Lau, F.C., Shukitt Hale, B., Joseph, J.A. 2007. Nutritional Intervention in Brain Aging: Reducing the Effects of Inflammation and Oxidative Stress. Inflammation in the Pathogenesis of Chronic Diseases:The COX-2 controversy. Subcellular Biochemistry. Volume 42. New York, NY:Springer Publication. p.299-318.
BENEFICIAL EFFECTS OF FRUIT EXTRACTS ON NEURONAL FUNCTION AND BEHAVIOR IN A RODENT MODEL OF ACCELERATED AGING -
Shukitt Hale, B., Carey, A.N., Jenkins, D., Rabin, B.M., Joseph, J.A. 2007. Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging. Neurobiology of Aging.28:1187-1194.
Beneficial effects of berryfruit polyphenols on neuronal behavioral aging -
Lau, F.C., Shukitt Hale, B., Joseph, J.A. 2006. Beneficial effects of berryfruit polyphenols on neuronal behavioral aging. Journal of the Science of Food and Agriculture.86:2251-2255.
DIETARY SUPPLEMENTATION WITH BLUEBERRY EXTRACT IMPROVES SURVIVAL OF TRANSPLANTED DOPAMINE NEURONS -
Mcguire, S.O., Sortwell, C.E., Shukitt Hale, B., Joseph, J.A., Hejna, M.J., Collier, T.J. 2006. Dietary supplementation with blueberry extract improves survival of transplanted dopamine neurons. Nutritional Neuroscience. 9(5/6): 251-258.
BHT blocks NfkB activation and Ethanol-Induced Brain Damage -
Crews, F.T., Nixon, K., Kim, D., Joseph, J.A., Shukitt Hale, B., Qin, L., Zou, J. 2006. Bht blocks nfkb activation and ethanol-induced brain damage. Alcoholism: Clinical and Experimental.30(11):1938-1949.
A blueberry-enriched antioxidant diet reduces an age-related deficit in one trial per day discriminative reward learning -
Goyarzu, P., Malin, D.H., Moon, W.D., Moy, E., Moy, D., Jennings, R., Lippold, S., Shukitt Hale, B., Joseph, J.A. 2006. A blueberry-enriched antioxidant diet reduces an age-related deficit in one trial per day discriminative reward learning. Society for Neuroscience Abstracts and Proceedings.
The cognitive impact of nutritional homocysteinemia in apolipoprotein-E deficient mice -
Troen, A.M., Shukitt Hale, B., Chao, W., Alburquerque, B., Smith, D.E., Selhub, J., Rosenberg, I. 2006. The cognitive impact of nutritional homocysteinemia in apolipoprotein-E deficient mice. Journal of Alzheimer's Disease. 9(4): 381-92.
Blueberries and the Aging Brain: Beyond Antioxidants -
Mark, D.A., Shukitt Hale, B., Joseph, J.A. 2006. Blueberries and the Aging Brain: Beyond Antioxidants. The Food Journal.49(2):50-55.
BLUEBERRY POLYPHENOLS INCREASE CAENORHABDITIS ELEGANS SURVIVAL DURING AGING AND THERMAL STRESS -
Wilson, M.A., Shukitt Hale, B., Kalt, W., Ingram, D.K., Joseph, J.A., Wolkow, C.A. 2006. Blueberry polyphenols increase caenorhabditis elegans survival during aging and thermal stress. Aging Cell. (5):55-68
AGE RELATED NEURONAL AND BEHAVIORAL DEFICITS ARE IMPROVED BY POLYPHENOL RICH BLUEBERRY SUPPLEMENTATION -
Lau, F.C., Shukitt Hale, B., Joseph, J.A. 2005. Age related neuronal and behavioral deficits are improved by polyphenol rich blueberry supplementation. CRC Press. p. 499.
THE BENEFICIAL EFFECTS OF FRUIT POLYPHENOLS ON BRAIN AGING -
Lau, F.C., Shukitt Hale, B., Joseph, J.A. 2005. The beneficial effects of fruit polyphenols on brain aging. Neurobiology of Aging. 26S:S128-S132.
EFFECTS OF CONCORD GRAPE JUICE ON COGNITIVE AND MOTOR DEFICITS IN AGING -
Shukitt Hale, B., Carey, A.N., Simon, L.E., Mark, D.A., Joseph, J.A. 2006. Effects of Concord Grape Juice on Cognitive and Motor Deficits in Aging. Nutrition. 22:295-302.
EFFECTS OF AGE AND EXPOSURE TO GOUND-BASED MODELS OF COSMIC RAYS ON ELEVATED PLUS MAZE PERFORMANCE IN RATS -
Carrihill-Knoll, K.L., Maloney, B.K., Rabin, B.M., Shukitt Hale, B., Joseph, J.A., Carey, A.N. 2005. Effects of age and exposure to gound-based models of cosmic rays on elevated plus maze performance in rats. Society for Neuroscience Abstracts and Proceedings. Abstract No. 656.10.
DIFFERENTIAL EFFECTS OF BLUEBERRY EXTRACT PREPARATIONS ON COGNTIVE AND MOTOR FUNCTION IN AGING: THE ROLE OF PHENOLICS -
Shukitt Hale, B., Carey, A.N., Kalt, W., Mcdonald, J., Vinqvist, M., Joseph, J.A. 2005. Differential effects of blueberry extract preparations on cogntive and motor function in aging: the role of phenolics. Society for Neuroscience Abstracts and Proceedings. Abstract No. 93.5.
OXIDATIVE STRESS AND INFLAMMATION IN BRAIN AGING: NUTRITIONAL CONSIDERATIONS -
Joseph, J.A., Shukitt Hale, B., Casadesus, G., Fisher, D.R. 2005. Oxidative stress and inflammation in brain aging: nutritional considerations. Neurochemical Research. Volume(30):927-935
THE EFFECTS OF ANTIOXIDANTS IN THE SENESCENT AUDITORY CORTEX -
De Rivera, C., Shukitt Hale, B., Joseph, J.A., Mendelson, J.R. 2006. The effects of antioxidants in the senescent auditory cortex. Neurobiology of Aging. 27(7):1035-1044.
DIETARY SUPPLEMENTATION WITH FRUIT POLYPHENOLICS AMELIORATES AGE-RELATED DEFICITS IN BEHAVIOR AND NEURONAL MARKERS OF INFLAMMATION AND OXIDATIVE STRESS -
Shukitt Hale, B., Meterko, V., Carey, A.N., Bielinski, D., Mcguie, T., Galli, R., Joseph, J.A. 2005. Dietary supplementation with fruit polyphenolics ameliorates age-related deficits in behavior and neuronal markers of inflammation and oxidative stress. Age. 2005, 27, 49-57.
REVERSING THE DELETERIOUS EFFECTS OF AGING ON NEURONAL COMMUNICATION AND BEHAVIOR: THE BENEFICIAL PROPERTIES OF FRUIT POLYPHENOLICS -
Joseph, J.A., Shukitt Hale, B., Casadesus, G. 2005. Reversing the deleterious effects of aging on neuronal communication and behavior: the beneficial properties of fruit polyphenolics. American Journal of Clinical Nutrition 2005, 81 (Suppl.) 313S-316S
EFFECT OF DIET ON THE DISRUPTION OF OPERANT RESPONDING AT DIFFERENT AGES FOLLOWING EXPOSURE TO FE56 PARTICLES -
Rabin, B.M., Carrihill-Knoll, K.L., Carey, A.N., Shukitt Hale, B., Joseph, J.A. 2005. Effect of diet on the disruption of operant responding at different ages following exposure to fe56 particles. Age. 205, 27, 69-73.
DIET AS A FACTOR IN BEHAVIORAL RADIATION PROTECTION FOLLOWING EXPOSURE TO HEAVY PARTICLES -
Rabin, B.M., Shukitt Hale, B., Joseph, J.A., Tood, P. 2005. Diet as a factor in behavioral radiation protection following exposure to heavy particles. American Society for Gravitation and Space Biology 18(2)June 2005.
ANTHOCYANINS IN AGED BLUEBERRY-FED RATS ARE FOUND CENTRALLY AND MAY ENHANCE MEMORY -
Andres-Lacueva, C., Shukitt Hale, B., Galli, R.L., Jaurengui, O., Lamuela-Raventos, R.M., Joseph, J.A. 2005. Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory. Nutritional Neuroscience, April 2005:8(2): 111-120.
BLUEBERRY SUPPLEMENTED DIET REVERSES AGE-RELATED DECLINE IN HIPPOCAMPAL HSP70 NEUROPROTECTION -
Galli, R.L., Bielinski, D.F., Szprengiel, A., Shukitt Hale, B., Joseph, J.A. 2006. Blueberry supplemented diet reverses age-related decline in hippocampal hsp70 neuroprotection. Neurobiology of Aging 27 (2006)344-350.
EFFECTS OF AGE AND DIET ON THE HEAVY PARTICLE-INDUCED DISRUPTIONS OF OPERANT RESPONDING PRODUCED BY A GROUND-BASED MODEL FOR EXPOSURE TO COSMIC RAYS -
Rabin, B.M., Joseph, J.A., Shukitt Hale, B., 2005. Effects of age and diet on the heavy particle-induced disruptions of operant responding produced by a ground-based model for exposure to cosmic rays. Brain Research 1036(2005) 122-129.
A LONGITUDINAL STUDY OF OPERANT RESPONDING IN RATS IRRADIATED AT TWO MONTHS OF AGE -
Rabin, B.M., Joseph, J.A., Shukitt Hale, B. 2005. A longitudinal study of operant responding in rats irradiated at two months of age. Radiation Research. 164:552-555.
MODULATION OF HIPPOCAMPAL PLASTICITY AND COGNITIVE BEHAVIOR BY SHORT-TERM BLUEBERRY SUPPLEMENTATION IN AGED RATS -
Casadesus, G., Shukitt Hale, B., Stellwagen, H.M., Zhu, X., Lee, H., Smith, M.A., Joseph, J.A. 2004. Modulation of hippocampal plasticity and cognitive behavior by short-term blueberry supplementation in aged rats. Nutritional Neuroscience, Volume 7 Number 5/6 (October/December 2004), pp.309-316
HIPPOCAMPAL NEUROGENESIS AND PSA-NCAM EXPRESSION FOLLOWING EXPOSURE TO 56FE PARTICLES MIMICS THAT SEEN DURING AGING -
Casadesus, G., Stellwagen, H.M., Shukitt Hale, B., Rabin, B.M., Joseph, J.A. 2005. Hippocampal neurogenesis and psa-ncam expression following exposure to 56fe particles mimics that seen during aging. Gerontology Journal. 40 249-254
FLAVONOIDS AND THE BRAIN: INTERACTIONS AT THE BLOOD BRAIN BARRIER AND THEIR PHYSIOLOGICAL EFFECT ON THE CNS -
Youdim, K.A., Shukitt Hale, B., Joseph, J.A. 2004. Flavonoids and the brain: interactions at the blood brain barrier and their physiological effect on the cns. Free Radical Biology and Medicine, VOL 37, NO11 PP. 1683-1693.
THE BENEFICIAL EFFECTS OF FRUIT AND VEGETABLE SUPPLEMENTATION ON NEURONAL SIGNALING AND BEHAVIOR IN AGING: BEYOND ANTIOXIDANTS -
Joseph, J.A., Shukitt Hale, B., Casadesus, G. 2006. The beneficial effects of fruit and vegetable supplementation on neuronal signaling and behavior in aging: beyond antioxidants. In: Stagg, J.J. and Foster, J. G. Editors. Nutrients, Stress and Medical Disorders. Totowa, MJ:Humana Press. p. 67-82
FRUIT POLYPHENOLS PREVENT INFLAMMATORY MEDIATED DECREMENTS IN COGNITION -
Shukitt Hale, B., Carey, A.N., Belinski, D., Lau, F.C., Galli, R.L., Spangler, E.L., Ingram, D.K., Joseph, J.A. 2004. Fruit polyphenols prevent inflammatory mediated decrements in cognition. Soc. Neurosci. Abs. 2004, 30,565.5.
NUTRITION AND COMMUNICATION IN THE AGED BRAIN: CAN YOU HEAR US NOW? -
Joseph, J.A., Shukitt Hale, B., Smith, M. 2004. Nutrition and communication in the aged brain: can you hear us now? Acarology International Congress Proceedings.
THE BENEFICIAL PROPERTIES OF FRUIT POLYPHENOLS ON NEURONAL COMMUNICATION AND BEHAVIOR IN AGING -
Joseph, J.A., Shukitt Hale, B., Casadesus, G. 2004. The beneficial properties of fruit polyphenols on neuronal communication and behavior in aging. In: Stagg, J.J., Foster, J.G. editors. Medicinal and Aromatic Plants: Production, Business and Applications. West Virginia: Mountain State University Press. p.18-30.
DIETARY SUPPLEMENTATION WITH BLUEBERRY EXTRACT DECREASES INFLAMMATION AFTER BRAIN INJURY IN RATS: IMPLICATIONS FOR NEURAL TRANSPLANTATION -
Mcguire, S.O., Hejna, M.J., Shukitt Hale, B., Joseph, J.A., Collier, T.J., Lorens, S.A. Dietary supplementation with blueberry extract decreases inflammation after brain injury in rats: implications for neural transplantation. 2004 Society for Neuroscience Abstracts and Proceedings.
BLUEBERRY SUPPLEMENTED DIET: EFFECTS ON OBJECT RECOGNITION MEMORY & NUCLEAR FACTOR KAPPA B LEVELS IN AGED RATS -
Goyarzu, P., Malin, D.H., Lau, F.C., Taglialatela, G., Moon, W.D., Jennings, R., Moy, E., Moy, D., Lippold, S., Shukitt Hale, B., Joseph, J.A. 2004. Blueberry supplemented diet: effects on object recognition memory & nuclear factor kappa b levels in aged rats. Nutritional Neuroscience. 7(2):75-83.
FRUIT POLYPHENOLICS AND SIGNALING IN THE AGED BRAIN:ALTERING MOTOR AND COGNITIVE DEFICITS -
Joseph, J.A., Shukitt Hale, B. 2004. Fruit polyphenolics and signaling in the aged brain:altering motor and cognitive deficits. In: Ozben, T., Chevion. M., editors. Frontiers in Aging and Neurodegenerative Disorders: Fundamental Aspects, Clinical Perspectives and New Insights. Amsterdam, The Netherlands:IOS Press. p. 170-181.
HEAVY PARTICLE IRRADIATION, NEUROCHEMISTRY AND BEHAVIOR: THRESHOLDS, DOSE-RESPONSE CURVES AND RECOVERY OF FUNCTION -
Rabin, B.M., Joseph, J.A., Shukitt Hale, B. 2004. Heavy particle irradiation, neurochemistry and behavior: thresholds, dose-response curves and recovery of function. Advances in Space Research. 33:1330-1333.
THE EFFECTS OF HEAVY PARTICLE IRRADIATION ON EXPLORATION AND RESPONSE TO ENVIRONMENTAL CHANGE -
Casadesus, G., Shukitt Hale, B., Cantuti-Castelvetri, I., Rabin, B.M., Joseph, J.A. 2004. The effects of heavy particle irradiation on exploration and response to environmental change. Advances in Space Research.
AGE-RELATED INCREASE IN BRAIN NFK-B IS ATTENUATED BY BLUEBERRY-ENRICHED ANTIOXIDANT DIET -
Goyarzu, P., Lau, F.C., Kaufmann, J., Jennings, R., Taglialatela, G., Shukitt Hale, B., Joseph, J.A., Malin, D. Age-related increase in brain nfk-b is attenuated by blueberry-enriched antioxidant diet. Soc. Neurosci. Abs. 2003, 29, 98.3
RATS FED A BLUEBERRY-ENRICHED DIET EXHIBIT GREATER PROTECTION AGAINST A KAINATE-INDUCED LEARNING IMPAIRMENT -
Spangler, E., Duffy, K., Devon, B., Guo, Z., Bowker, J., Shukitt Hale, B., Joseph, J.A., Ingram, D.K. 2003. Rats fed a blueberry-enriched diet exhibit greater protection against a kainate-induced learning impairment. Soc. Neurosci. Abs. 2003, 29, 638.12.
AGE-RELATED INCREASED IN BRAIN NF-KB IS ATTENUATED BY BLUEBERRY-ENRICHED ANTIOXIDANT DIET -
Goyarzu, P., Lau, F.C., Kaufmann, J., Jennings, R., Taglialatela, G., Shukitt Hale, B., Joseph, J.A., Malin, D. 2003. Age-related increased in brain nf-kb is attenuated by blueberry-enriched antioxidant diet. Society for Neuroscience Abstracts and Proceedings.
EFFECTS OF ANTIOXIDANT DIETS ON AGE- AND HEAVY PARTICLE-INDUCED DISRUPTION OF OPERANT RESPONDING IN RATS -
Rabin, B.M., Jenkins, D.G., Joseph, J.A., Shukitt Hale, B. 2003. Effects of antioxidant diets on age- and heavy particle-induced disruption of operant responding in rats. Society for Neuroscience Abstracts and Proceedings.
MECHANISMS INVOLVED IN BLUEBERRY ENHANCEMENTS OF MOTOR AND COGNITIVE FUNCTION IN YOUNG AND OLD RATS -
Shukitt Hale, B., Carey, A.N., Casadesus, G., Galli, R.L., Joseph, J.A. 2003. Mechanisms involved in blueberry enhancements of motor and cognitive function in young and old rats. Soc. Neurosci. Abs. 2003, 29. 633.14
PHYTOCHEMICALS IN FOODS AND EVERAGES: EFFECTS ON THE CNS -
Shukitt Hale, B., Carey, A.N., Joseph, J.A. Phytochemicals in foods and everages: Effects on the Central Nervous System. In lieberman, H.R., Kanarek, R.B., and Prasad, C.eds. Nutritional Neuroscience. CRC Press, Taylor & Francis Group, LLC Boca Raton, FL, 2005, 393-404.
BLUEBERRY SUPPLEMENTATION ENHANCES SIGNALING AND PREVENTS BEHAVIORAL DEFICITS IN ALZHEIMER DISEASE MODEL -
Joseph, J.A., Arendash, G., Gordon, M., Diamond, D., Shukitt Hale, B., and Morgan, D. Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr. Neurosci. 2003, 6: 153-162.
EFFECT OF AGE ON THE RADIAL ARM WATER MAZE - A TEST OF SPATIAL LEARNING AND MEMORY -
Shukitt Hale, B., Szprengiel, A., Joseph, J.A. 2004. Effect of age on the radial arm water maze - a test of spatial learning and memory. Neurobiology of Aging. 25(2):223-229.
COGNITIVE DEFICITS INDUCED BY 56FE RADIATION EXPOSURE -
Shukitt-Hale, B., Casadesus, G., Cantuti-Castelvetri, I., Rabin, B.M., and Joseph, J.A. Cognitive deficits induced by 56Fe radiation exposure. Adv. Space Res. 2003, 31: 119-126.
LONG-TERM CHANGES IN AMPHETAMINE-INDUCED REINFORCEMENT AND AVERSION IN RATS FOLLOWING EXPOSURE TO 56FE PARTICLES -
Rabin, B.M., Joseph, J.A., and Shukitt-Hale, B. Long-term changes in amphetamine-induced reinforcement and aversion in rats following exposure to 56Fe particles. Adv. Space Res. 2003, 31: 127-133.
BRAIN SIGNALING AND BEHAVIORAL RESPONSES INDUCED BY EXPOSURE TO 56FE RADIATION -
DENISOVA, N.A., SHUKITT HALE, B., RABIN, B., JOSEPH, J.A. BRAIN SIGNALING AND BEHAVIORAL RESPONSES INDUCED BY EXPOSURE TO 56FE RADIATION. RADIATION RESEARCH. 2002.158(6):725-34.
DOPAMINE NEUROTOXICITY: AGE-DEPENDENT BEHAVIORAL AND HISTOLOGICAL EFFECTS -
Cantuti-Castelvetri, I., Shukitt-Hale, B., and Joseph, J.A. Dopamine neurotoxicity: Age-dependent behavioral and histological effects. Neurobio. Aging 2003, 24: 697-706.
INTERACTION BETWEEN HEAVY PARTICLES IRRADIATION AND AGE IN THE DISRUPTION OF FIXED-RATION OPERANT RESPONDING IN RATS -
Rabin, B.M., Shukitt-Hale, B., Joseph, J.A., Buhler, L.L., Jenkins, D.G., and Eggleston, A.M. Interaction between heavy particle irradiation and age in the disruption of fixed - ratio operant responding in rats. Soc. Neurosci. Abs. 2002, 28, 889.11.
POLYPHENOLICS CAN LOCALIZE WITHIN THE BRAINS OF AGED RATS FED A BLUEBERRY-SUPPLEMENTED DIET -
Shukitt-Hale, B., Andres-Lacueva, C., Galli, R.L., Jauregui, O., Lamuela-Raventos, R.M., and Joseph, J.A. Polyphenolics can localize within the brains of aged rats fed a blueberry - supplemented diet. Soc. Neurosci. Abs. 2002, 28, 294.6. 
MODULATION OF HIPPOCAMPAL NEUROGENESIS AND COGNITIVE PERFORMANCE IN THE AGED RAT: THE BLUEBERRY EFFECT -
Casadesus, G., Stellwagen, H., Szprengiel, A., Galli, R.L., Smith, M.A., Shukitt Hale, B., Joseph, J.A. 2002. Modulation of hippocampal neurogenesis and cognitive performance in the aged rat: the blueberry effect. Society for Neuroscience Abstracts and Proceedings.
DIETARY SUPPLEMENTATION WITH FRUIT POLYPHENOLICS AMELIORATES AGE-RELATED DEFICITS IN BEHAVIOR AND NEURONAL MARKERS OF INFLAMMATION AND OXIDATIVE STRESS -
Galli, R.L., Shukitt Hale, B., Bielinski, D.F., Andres-Lacueva, C., Joseph, J.A. 2002. Dietary supplementation with fruit polyphenolics ameliorates age-related deficits in behavior and neuronal markers of inflammation and oxidative stress. Society for Neuroscience Abstracts and Proceedings.
DIETARY SUPPLEMENTATION WITH BLUEBERRY EXTRACTS IMPROVES THE SURVIVAL AND FUNCTION OF GRAFTED EMBRYONIC DOPAMINE NEURONS IN RATS -
Mcguire, S.O., Shukitt Hale, B., Joseph, J.A., Sortwell, C.E., Fleming, M.F., Marchionini, D.M., Kanaan, N.M., Daley, B., Collier, T.J. 2002. Dietary supplementation with blueberry extracts improves the survival and function of grafted embryonic dopamine neurons in rats. Society for Neuroscience Abstracts and Proceedings.
EFFECTS OF HEAVY PARTICLES IRRADIATION AND DIET ON AMPHETAMINE- AND LITHIUM CHLORIDE-INDUCED TASTE AVOIDANCE LEARNING IN RATS -
RABIN, B.M., SHUKITT HALE, B., SZPRENGIEL, A., JOSEPH, J.A. EFFECTS OF HEAVY PARTICLES IRRADIATION AND DIET ON AMPHETAMINE- AND LITHIUM CHLORIDE-INDUCED TASTE AVOIDANCE LEARNING IN RATS. BRAIN RESEARCH.853:31-6.
PRACTICING CALORIC RESTRICTION OR EATING A DIET HIGH IN ANTIOXIDANTS: EQUIVALENT PATHS TO SUCCESSFUL AGING? -
CASADESUS, G., SHUKITT HALE, B., JOSEPH, J.A. PRACTICING CALORIC RESTRICTION OR EATING A DIET HIGH IN ANTIOXIDANTS: EQUIVALENT PATHS TO SUCCESSFUL AGING?. NEUROBIOLOGY OF AGING. 23(5):747-69,2002.
AGE-RELATED DECLINES IN THE LOCOMOTOR RESPONSE TO ENVIRONMENTAL NOVELTY ANDHOME-CAGE ACTIVITY -
Casadesus, G., Shukitt-Hale, B., and Joseph, J.A. Automated measurement of age-related changes in the locomotor response to environmental novelty and home-cage activity. Mech. Ageing Develop. 2001, 122: 1887 1897.
EFFECT OF AGE ON OBJECT EXPLORATION, HABITUATION, AND RESPONSE TO SPATIAL AAND NON-SPATIAL CHANGE -
Shukitt-Hale, B., Casadesus, G., Cantuti-Castelvetri, I., and Joseph, J.A. Effect of age on object exploration, habituation, and response to spatial and non-spatial change. Behav. Neurosci. 2001, 115: 1059-1064.
SHORT-TERM DIETARY SUPPLEMENTATION OF BLUEBERRY POLYPHENOLICS: BENEFICIAL EFFECTS ON AGING BRAIN PERFORMANCE AND PERIPHERAL TISSUE FUNCTION -
Youdim, K.A., Shukitt-Hale, B., Martin, A., Wang, H., Denisova, N., Bickford, P.C., and Joseph, J.A. Short-term dietary supplementation of blueberry polyphenolics: Beneficial effects on aging brain performance and peripheral tissue function. Nutr. Neurosci. 2000, 3: 383-397.
EFFECTS OF EXPOSURE TO 56FE PARTICLES ON THE ACQUISITION OF A CONDITIONED PLACE PREFERENCE IN RATS -
Rabin, B. M., Shukitt-Hale, B., Joseph, J. A., and Denisova, N. Effects of exposure to 56Fe particles on the acquisition of a conditioned place preference in rats. Physica Medica 2001, 17 (Suppl. 1): 196-197.
PSYCHOMOTOR AND SPATIAL MEMORY PERFORMANCE IN AGING MALE FISCHER 344 RATS -
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Last Modified: 5/2/2016
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